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Filip Garbicz
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Journal Articles

A Novel Ribonuclease Targeting Small Molecule RNA-Degrader (MYC-RiboTAC) Overcomes MYC Dependency in Multiple Myeloma

Domenico Maisano, Tenghui Wang, Yuquan Tong, Vanessa Favasuli, Na Liu, Claire Gao, Chandraditya Chakraborty, Giulia Giorgetti, Francesco Ladisa, Marcello Turi, Francesca Barello, Michela Cumerlato, Anil Aktas-Samur, Mehmet K. Samur, Michael Cameron, Filip Garbicz, Ruben D. Carrasco, Mariateresa Fulciniti, Annamaria Gulla, Jessica Childs-Disney, Matthew D. Disney, Eugenio Morelli, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2024-205528
Published: 2024
Journal Articles

CDK12/13: A Promising New Therapeutic Target in ALL

Julia Dudkiewicz, Filip Garbicz, Pawel Krzysztof Wlodarski
Journal: Blood
Blood (2023) 142 (Supplement 1): 2266.
https://doi.org/10.1182/blood-2023-190038
Published: 2023
Journal Articles

Transcriptomic Features Influencing Anti-Myeloma Drug Resistance in Human Multiple Myeloma Cell Lines

Filip Garbicz, Irena Misiewicz-Krzeminska, Ruben D. Carrasco, Przemysław Juszczyński
Journal: Blood
Blood (2023) 142 (Supplement 1): 1943.
https://doi.org/10.1182/blood-2023-190247
Published: 2023
Journal Articles

PIM1 Point Mutations Increase Migration of Diffuse Large B-Cell Lymphoma (DLBCL) Cells

Aleksandra Zolyniak, Dorota Komar, Sonia Debek, Filip Garbicz, Michal Pawlak, Przemysław Juszczyński
Journal: Blood
Blood (2023) 142 (Supplement 1): 2772.
https://doi.org/10.1182/blood-2023-189077
Published: 2023
Journal Articles

Epigenetic and Transcriptional Consequences of PIM Kinase Activity and Inhibition in Diffuse Large B-Cell Lymphoma (DLBCL)

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Zolyniak, Michal Pawlak, Ewa Jablonska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Małgorzata Bajor, Nazli Serin, Bjoern Chapuy, Przemysław Juszczyński
Journal: Blood
Blood (2023) 142 (Supplement 1): 5713.
https://doi.org/10.1182/blood-2023-189958
Published: 2023
Journal Articles

Immunoregulatory CD71 + Erythroid Cells (CECs) Expand in Multiple Myeloma and Impair Control of L. Monocytogenes Infection

Tomasz M. Grzywa, Karol Czubak, Karolina Sidor, Zofia Pilch, Aneta Bragiel-Pieczonka, Grazyna Hoser, Anna Rodziewicz-Lurzynska, Milena Małecka-Giełdowska, Joanna Barankiewicz, Filip Garbicz, Olga Ciepiela, Przemyslaw Juszczynski, Michal Wegrzynowicz, Tomasz Skirecki, Jakub Golab, Dominika Nowis
Journal: Blood
Blood (2022) 140 (Supplement 1): 12538–12539.
https://doi.org/10.1182/blood-2022-164577
Published: 2022
Journal Articles

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Filip Garbicz, Sonia Debek, Anna Szumera-Ciećkiewicz, Joanna Barankiewicz, Dorota Komar, Michał Pawlak, Aleksandra Matrejek, Thorsten Stuehmer, Aleksander Salomon-Perzynski, Agata Malenda, Julia Ostrowska, Julia Dudkiewicz, Krzysztof Brzózka, Tomasz Rzymski, Daniela Bellarosa, Ewa Lech-Marańda, Monika Prochorec-Sobieszek, Zofia Pilch, Dominika Nowis, Jakub Golab, Helen Tanton, Teru Hideshima, David M. Dorfman, Irena Misiewicz-Krzeminska, Tomasz Sewastianik, Ruben D. Carrasco, Maciej Szydlowski, Przemyslaw Juszczynski
Journal: Blood
Blood (2022) 140 (Supplement 1): 4189–4190.
https://doi.org/10.1182/blood-2022-168770
Published: 2022
Journal Articles

PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Matrejek, Michał Pawlak, Ewa Jabłońska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Daniela Bellarosa, Nazli Serin, Malgorzata Bajor, Bjoern Chapuy, Przemyslaw Juszczynski
Journal: Blood
Blood (2022) 140 (Supplement 1): 3044–3045.
https://doi.org/10.1182/blood-2022-167734
Published: 2022
Journal Articles

MEN1703-Mediated PIM Kinases Inhibition Impairs Protumoral and Immunosuppressive Phenotype and Functions of Macrophages in Classical Hodgkin Lymphoma

Maciej Szydlowski, Filip Garbicz, Ewa Kurtz, Justyna Żurańska, Michał Seweryn, Michał Pawlak, Patryk Górniak, Kamil Sokół, Anna Szumera-Ciećkiewicz, Monika Kawecka, Daria Owczarek, Beata Puton, Monika Prochorec-Sobieszek, Daniela Bellarosa, Michał Kurlapski, Jan Zaucha, Paweł Wołkow, Przemyslaw Juszczynski
Journal: Blood
Blood (2022) 140 (Supplement 1): 6441–6442.
https://doi.org/10.1182/blood-2022-156894
Published: 2022
Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Maciej Szydlowski, PhD, Filip Garbicz, MD, Ewa Jabłońska, PhD, Patryk Górniak, PhD, Beata Pyrzynska, PhD, Kamil Bojarczuk, PhD, Dorota Komar, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Ciećkiewicz, MD PhD, Grzegorz Rymkiewicz, MDPhD, Magdalena Cybulska, DVM, Małgorzata Statkiewicz, Marta Gajewska, PhD, MIchał Mikula, PhD, Aniela Golas, PhD, Joanna Domagała, MSc, Magdalena Winiarska, Agnieszka Graczyk-Jarzynka, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Joanna Barankiewicz, MD, Bartosz Pula, MDPhD, Michael R Green, PhD, Dominika Nowis, MD PhD, Jakub Golab, Andrea Massimiliano Tomirotti, PhD, Krzysztof Brzózka, PhD, Mariana Pacheco-Blanco, Kristyna Kupcova, Ondrej Havranek, MDPhD, Bjoern Chapuy, MDPhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-134778
Published: 2020
Journal Articles

Hodgkin Lymphoma Reed-Sternberg Cells Induce Immunosuppressive and Pro-Angiogenic Phenotype of Tumor-Associated Macrophages in a Paracrine Manner

Maciej Szydlowski, PhD, Michał Pawlak, PhD, Filip Garbicz, MD, Patryk Górniak, PhD, Justyna Żurańska, PhD, Magdalena Król, PhD, Bartłomiej Taciak, Maciej Białasek, Anna Szumera-Ciećkiewicz, MD PhD, Kamil Sokół, Monika Stańczak, Msc, Daria Owczarek, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Emilia Bialopiotrowicz, PhD, Michał Kurlapski, Jan Zaucha, MDPhD, Paweł Wołkow, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-134886
Published: 2020
Journal Articles

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Filip Garbicz, MD, Anna Szumera-Ciećkiewicz, MD PhD, Joanna Barankiewicz, MD, Dorota Komar, PhD, Michał Pawlak, PhD, Sonia Dębek, MSc, Aleksandra Matrejek, MSc, Thorsten Stuehmer, PhD, Aleksander Salomon-Perzynski, MD, Agata Malenda, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Andrea Massimiliano Tomirotti, PhD, Ewa Lech-Marańda, MD PhD, Monika Prochorec-Sobieszek, MD PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134979
Published: 2020