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Michael Cameron
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Journal Articles

REM-422, a Small Molecule MYB mRNA Degrader, Demonstrates Anti-Leukemic Activity As Monotherapy and in Combination with Standards of Care in Preclinical Models of AML

Samantha Levin-Furtney, Michael Thomas, Alycen M. Harney, Mengge Shan, Alexander Ivliev, Adam Stefek, Michael Cameron, Sudeep Prajapati, Michael Seiler, Dominic Reynolds, Silvia Buonamici, Charles Kung
Journal: Blood
Blood (2024) 144 (Supplement 1): 826.
https://doi.org/10.1182/blood-2024-208725
Published: 2024
Journal Articles

A Novel Ribonuclease Targeting Small Molecule RNA-Degrader (MYC-RiboTAC) Overcomes MYC Dependency in Multiple Myeloma

Domenico Maisano, Tenghui Wang, Yuquan Tong, Vanessa Favasuli, Na Liu, Claire Gao, Chandraditya Chakraborty, Giulia Giorgetti, Francesco Ladisa, Marcello Turi, Francesca Barello, Michela Cumerlato, Anil Aktas-Samur, Mehmet K. Samur, Michael Cameron, Filip Garbicz, Ruben D. Carrasco, Mariateresa Fulciniti, Annamaria Gulla, Jessica Childs-Disney, Matthew D. Disney, Eugenio Morelli, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2024-205528
Published: 2024
Journal Articles

REM-422, a Potent, Selective, Oral Small Molecule mRNA Degrader of the MYB Oncogene, Demonstrates Anti-Tumor Activity in Mouse Xenograft Models of AML

Sudeep Prajapati, Michael Cameron, Bryan M. Dunyak, Mengge Shan, Y. Amy Siu, Samantha Levin-Furtney, Joshua Powe, Eileen T.M. Burchfiel, Sarah E. Cabral, Alycen M. Harney, Regina K. Keenan, Kevin M. Larpenteur, Jesper L.V. Maag, Andrew R. Snyder, Dan T. Nguyen, Cecile Blaustein, Silvia Buonamici, Dominic Reynolds, Matthew J. Schnaderbeck, Michael Seiler, Frédéric H. Vaillancourt, Peter Smith, Zaven Kaprielian, Charles Kung
Journal: Blood
Blood (2023) 142 (Supplement 1): 1425.
https://doi.org/10.1182/blood-2023-182676
Published: 2023
Journal Articles

The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTK Cys481 ibrutinib resistance

Guang Yang, Jinhua Wang, Li Tan, Manit Munshi, Xia Liu, Amanda Kofides, Jiaji G. Chen, Nicholas Tsakmaklis, Maria G. Demos, Maria Luisa Guerrera, Lian Xu, Zachary R. Hunter, Jinwei Che, Christopher J. Patterson, Kirsten Meid, Jorge J. Castillo, Nikhil C. Munshi, Kenneth C. Anderson, Michael Cameron, Sara J. Buhrlage, Nathanael S. Gray, Steven P. Treon
Journal: Blood
Blood (2021) 138 (20): 1966–1979.
https://doi.org/10.1182/blood.2021011405
Published: 2021
Includes: Supplemental data
Journal Articles

Mechanisms of Globin Regulation and Modeling Fetal Hemoglobin Reactivation

Billy Stuart, Michael Cameron, Angela Cacace, Peter Rahl
Journal: Blood
Blood (2017) 130 (Supplement 1): 4768.
https://doi.org/10.1182/blood.V130.Suppl_1.4768.4768
Published: 2017
Journal Articles

Discovery of a small-molecule type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRα, Kit, and Src kinases: novel type II inhibitor of gatekeeper mutants

Ellen Weisberg, Hwan Geun Choi, Arghya Ray, Rosemary Barrett, Jianming Zhang, Taebo Sim, Wenjun Zhou, Markus Seeliger, Michael Cameron, Mohammed Azam, Jonathan A. Fletcher, Maria Debiec-Rychter, Mark Mayeda, Daisy Moreno, Andrew L. Kung, Pasi Antero Janne, Roya Khosravi-Far, Junia V. Melo, Paul W. Manley, Sophia Adamia, Catherine Wu, Nathanael Gray, James D. Griffin
Journal: Blood
Blood (2010) 115 (21): 4206–4216.
https://doi.org/10.1182/blood-2009-11-251751
Published: 2010
Includes: Supplemental data