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Journal Articles

Title: Single-Cell Transcriptome Analyses Further Elucidate the Mechanism of Action of Eed Inhibition on HbF Induction

Summer Xia Han, Emily M Fitz, Allysa Allen, Avik Choudhuri, Caroline V Sartain, Paul A Bruno, Jeffrey W Jacobs, Billy Stuart
Journal: Blood
Blood (2023) 142 (Supplement 1): 3870.
https://doi.org/10.1182/blood-2023-189996
Published: 2023
Journal Articles

HbF Inducing Eed Inhibitor Ftx-6058 Selectively and Reversibly Impacts Bone Marrow in Wild-Type Mice

Emily M Fitz, Allysa Allen, Lynn Edwards, Suchi Raghunathan, Briana Steward, David J Matson, Caroline V Sartain, Paul A Bruno, Jeffrey W Jacobs, Billy Stuart
Journal: Blood
Blood (2023) 142 (Supplement 1): 5265.
https://doi.org/10.1182/blood-2023-190115
Published: 2023
Journal Articles

Ftx-6058 Induces Fetal Hemoglobin Production and Ameliorates Disease Pathology in Sickle Cell Mice

David Matson, Keqiang Xie, Mark Roth, Billy Stuart, Paul Bruno, Ivan Efremov, Lorin Thompson, Serena Silver, Christopher Moxham
Journal: Blood
Blood (2021) 138 (Supplement 1): 2018.
https://doi.org/10.1182/blood-2021-151426
Published: 2021
Journal Articles

Induction of Fetal Hemoglobin By FTX6058, a Novel Small Molecule Development Candidate

Peter Rahl, Ivan Efremov, Billy Stuart, Keqiang Xie, Mark Roth, Richard Barnes, Kingsley Appiah, David Peters, Qingyi Li, Steven Kazmirski, Paul Bruno, Kim Stickland, Lucienne Ronco, Diego Cadavid, Lorin Thompson, Owen Wallace, Christopher Moxham
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-142056
Published: 2020
Journal Articles

In Vitro Characterization of FTX6058, a Novel Small Molecule Fetal Hemoglobin Inducer for Sickle Cell Disease

Billy Stuart, Peter Rahl, Kingsley Appiah, Ivan Efremov, Lorin Thompson, Owen Wallace, Christopher Moxham
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
https://doi.org/10.1182/blood-2020-141145
Published: 2020
Journal Articles

Mechanisms of Globin Regulation and Modeling Fetal Hemoglobin Reactivation

Billy Stuart, Michael Cameron, Angela Cacace, Peter Rahl
Journal: Blood
Blood (2017) 130 (Supplement 1): 4768.
https://doi.org/10.1182/blood.V130.Suppl_1.4768.4768
Published: 2017