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Journal Articles

Measuring H3K27me3 Reduction after in-Vivo Administration of Ftx-6058; A Potent Polycomb Repressive Complex 2 (PRC2) Inhibitor

Mark Roth, Keqiang Xie

Blood (2021) 138 (Supplement 1): 4164.

https://doi.org/10.1182/blood-2021-150770

Published: 2021

Journal Articles

Ftx-6058 Induces Fetal Hemoglobin Production and Ameliorates Disease Pathology in Sickle Cell Mice

David Matson, Keqiang Xie, Mark Roth, Billy Stuart, Paul Bruno, Ivan Efremov, Lorin Thompson, Serena Silver, Christopher Moxham

Blood (2021) 138 (Supplement 1): 2018.

https://doi.org/10.1182/blood-2021-151426

Published: 2021

Journal Articles

In Vivo Characterization of Ftx-6058, a Novel Small Molecular Fetal Hemoglobin Inducer for Sickle Cell Disease

Keqiang Xie, Mark Roth, Ivan Efremov, Serena Silver, Lucienne Ronco, Lorin Thompson, Kim Stickland, Christopher Moxham, Owen Wallace

Blood (2020) 136 (Supplement 1): 26–27.

https://doi.org/10.1182/blood-2020-139566

Published: 2020

Journal Articles

Induction of Fetal Hemoglobin By FTX6058, a Novel Small Molecule Development Candidate

Peter Rahl, Ivan Efremov, Billy Stuart, Keqiang Xie, Mark Roth, Richard Barnes, Kingsley Appiah, David Peters, Qingyi Li, Steven Kazmirski, Paul Bruno, Kim Stickland, Lucienne Ronco, Diego Cadavid, Lorin Thompson, Owen Wallace, Christopher Moxham

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-142056

Published: 2020