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Ewa Jablonska
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Journal Articles

Epigenetic and Transcriptional Consequences of PIM Kinase Activity and Inhibition in Diffuse Large B-Cell Lymphoma (DLBCL)

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Zolyniak, Michal Pawlak, Ewa Jablonska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Małgorzata Bajor, Nazli Serin, Bjoern Chapuy, Przemysław Juszczyński
Journal: Blood
Blood (2023) 142 (Supplement 1): 5713.
https://doi.org/10.1182/blood-2023-189958
Published: 2023
Journal Articles

PIM Kinases Regulate Super-Enhancer-Dependent Gene Expression in Diffuse Large B-Cell Lymphoma

Sonia Debek, Dorota Komar, Filip Garbicz, Aleksandra Matrejek, Michał Pawlak, Ewa Jabłońska, Maciej Szydlowski, Magdalena Skrzypczak, Sylwia Radomska, Daniela Bellarosa, Nazli Serin, Malgorzata Bajor, Bjoern Chapuy, Przemyslaw Juszczynski
Journal: Blood
Blood (2022) 140 (Supplement 1): 3044–3045.
https://doi.org/10.1182/blood-2022-167734
Published: 2022
Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Maciej Szydlowski, PhD, Filip Garbicz, MD, Ewa Jabłońska, PhD, Patryk Górniak, PhD, Beata Pyrzynska, PhD, Kamil Bojarczuk, PhD, Dorota Komar, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Ciećkiewicz, MD PhD, Grzegorz Rymkiewicz, MDPhD, Magdalena Cybulska, DVM, Małgorzata Statkiewicz, Marta Gajewska, PhD, MIchał Mikula, PhD, Aniela Golas, PhD, Joanna Domagała, MSc, Magdalena Winiarska, Agnieszka Graczyk-Jarzynka, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Joanna Barankiewicz, MD, Bartosz Pula, MDPhD, Michael R Green, PhD, Dominika Nowis, MD PhD, Jakub Golab, Andrea Massimiliano Tomirotti, PhD, Krzysztof Brzózka, PhD, Mariana Pacheco-Blanco, Kristyna Kupcova, Ondrej Havranek, MDPhD, Bjoern Chapuy, MDPhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-134778
Published: 2020
Journal Articles

SIRT1 and HSP90alpha Are Functionally Linked and Control Mitotic Chromosome Segregation and Cell Viability in a Subset of Dlbcls

Emilia Bialopiotrowicz, PhD, Monika Noyszewska-Kania, MSc, Ewa Jabłońska, PhD, Tomasz Sewastianik, PhD, Monika Stańczak, Msc, Anna Szumera-Ciećkiewicz, MD PhD, Katarzyna Borg, PhD, Aleksandra Bluszcz, Msc, Sonia Dębek, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Polak, PhD, Patryk Górniak, PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-139319
Published: 2020
Journal Articles

Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma

Maciej Szydłowski, Monika Prochorec-Sobieszek, Anna Szumera-Ciećkiewicz, Edyta Derezińska, Grażyna Hoser, Danuta Wasilewska, Olga Szymańska-Giemza, Ewa Jabłońska, Emilia Białopiotrowicz, Tomasz Sewastianik, Anna Polak, Wojciech Czardybon, Michał Gałęzowski, Renata Windak, Jan Maciej Zaucha, Krzysztof Warzocha, Krzysztof Brzózka, Przemysław Juszczyński
Journal: Blood
Blood (2017) 130 (12): 1418–1429.
https://doi.org/10.1182/blood-2017-01-760702
Published: 2017
Includes: Supplemental data
Journal Articles

Functional Link Between Heat Shock Protein HSP90alpha and Sirtuin 1 (SIRT1) in the Pathogenesis of Diffuse Large B Cell Lymphoma

Emilia Bialopiotrowicz, PhD, Tomasz Sewastianik, PhD, Monika Noyszewska-Kania, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Patryk Gorniak, PhD, Anna Polak, PhD, Przemyslaw Kiliszek, PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4120.
https://doi.org/10.1182/blood.V128.22.4120.4120
Published: 2016
Journal Articles

Downregulation of Deptor By MiR-155 Promotes Cell Survival through Activation of PI3K/AKT and NFkB Signaling in ABC-Type Diffuse Large B-Cell Lymphomas

Ewa Jablonska, PhD, Patryk Gorniak, PhD, Weronika Prusisz, MSc, Przemyslaw Kiliszek, PhD, Maciej Szydlowski, PhD, Tomasz Sewastianik, PhD, Emilia Bialopiotrowicz, PhD, Anna Polak, PhD, Monika Prochorec-Sobieszek, MD PhD Prof, Anna Szumera-Cieckiewicz, MD PhD, Krzysztof Warzocha, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1761.
https://doi.org/10.1182/blood.V128.22.1761.1761
Published: 2016
Journal Articles

Microenvironment-Induced Expression of PIM Kinases Supports Chronic Lymphocytic Leukemia Cells Survival and Promotes CXCR4-mTOR Pathway Dependent Migration

Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Bartosz Pula, MD PhD, Monika Noyszewska-Kania, MSc, Hanna Makuch-Lasica, MSc, Grazyna Nowak, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Tomasz Sewastianik, PhD, Anna Polak, PhD, Ewa Lech-Maranda, MD PhD, Bozena Katarzyna Budziszewska, MD PhD, Maja Wasylecka, MD, Katarzyna Borg, PhD, Krzysztof Warzocha, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3239.
https://doi.org/10.1182/blood.V128.22.3239.3239
Published: 2016
Journal Articles

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas

Maciej Szydlowski, Przemyslaw Kiliszek, Tomasz Sewastianik, Ewa Jablonska, Emilia Bialopiotrowicz, Patryk Gorniak, Anna Polak, Sergiusz Markowicz, Eliza Nowak, Monika A. Grygorowicz, Monika Prochorec-Sobieszek, Anna Szumera-Cieckiewicz, Agata Malenda, Ewa Lech-Maranda, Krzysztof Warzocha, Przemyslaw Juszczynski
Journal: Blood
Blood (2016) 127 (6): 739–748.
https://doi.org/10.1182/blood-2015-06-654111
Published: 2016
Includes: Supplemental data
Journal Articles

MiR-155 Amplifies AKT and NFkB Signaling By Targeting Multiple Regulators of BCR Signal in DLBCL

Ewa Jablonska, PhD, Patryk Gorniak, PhD, Weronika Prusisz, MSc, Przemyslaw Kiliszek, MSc, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Emilia Bialopiotrowicz, PhD, Anna Polak, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2455.
https://doi.org/10.1182/blood.V126.23.2455.2455
Published: 2015
Journal Articles

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Anna Polak, MSc, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Dominika Nowis, MDPhD, Jakub Golab, MD PhD, Sebastian Giebel, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4917.
https://doi.org/10.1182/blood.V126.23.4917.4917
Published: 2015
Journal Articles

FOXO1-p300-Txn Circuit Regulates Oxidative Stress Responses in Diffuse Large B-Cell Lymphomas Characterized By Enhanced Oxidative Phosphorylation

Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Emilia Bialopiotrowicz, PhD, Ewa Jablonska, PhD, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Tomasz S. Kaminski, MSc, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 466.
https://doi.org/10.1182/blood.V126.23.466.466
Published: 2015
Journal Articles

FOXO1 Activation Is an Effector of SYK and AKT Inhibition in Tonic BCR Signal-Dependent Diffuse Large B-Cell Lymphomas

Przemyslaw Kiliszek, MSc, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Anna Polak, MSc, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Agata Malenda, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 314.
https://doi.org/10.1182/blood.V126.23.314.314
Published: 2015
Journal Articles

Expression of PIM Kinases in Reed-Sternberg Cells Fosters Immune Privilege and Tumor Cell Survival in Classical Hodgkin Lymphoma

Maciej Szydlowski, PhD, Monika Prochorec-Sobieszek, MD PhD, Anna Szumera-Cieckiewicz, MD PhD, Grazyna Hoser, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Anna Polak, MSc, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Krzysztof Warzocha, MD PhD, Jan Maciej Zaucha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 819.
https://doi.org/10.1182/blood.V126.23.819.819
Published: 2015
Journal Articles

Activity of PIM Kinases in Chronic Lymphocytic Leukemia Modulates Tumor Cell Survival and Stromal Interactions through a Pleiotropic Mechanism Involving Modulation of CXCR4 - mTOR Pathway

Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Maciej Szydlowski, PhD, Tomasz Sewastianik, MSc, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Ewa Jablonska, PhD, Bozena Katarzyna Budziszewska, MD PhD, Bartosz Pula, MD, Maja Wasylecka, MD, Katarzyna Borg, PhD, Hanna Makuch-Lasica, MSc, Grazyna Nowak, MSc, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Krzysztof Brzozka, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1549.
https://doi.org/10.1182/blood.V126.23.1549.1549
Published: 2015
Journal Articles

HIF1-Alpha and MYC Transcription Factor Signatures in B-Cell Acute Lymphoblastic Leukemia Are Associated with Positive Minimal Residual Disease Status: Therapeutic Implications

Tomasz Sewastianik, MSc, Patryk Gorniak, PhD, Przemyslaw Kiliszek, MSc, Anna Polak, MSc, Emilia Bialopiotrowicz, PhD, Ewa Jablonska, PhD, Maciej Szydlowski, PhD, Ewa Lech-Maranda, MD PhD, Katarzyna Borg, PhD, Hanna Makuch-Lasica, MSc, Adam Zabek, MSc, Piotr Mlynarz, PhD, Tomasz Stoklosa, MD PhD, Sebastian Giebel, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1436.
https://doi.org/10.1182/blood.V126.23.1436.1436
Published: 2015
Journal Articles

A Novel Pan-PIM Kinase Inhibitor, SEL24-B489, Induces Apoptosis and Inhibits Proliferation of Diffuse Large B-Cell Lymphoma Cells through Inhibition of Protein Translation and Attenuation of Myc and NFkB Activity

Ewa Jablonska, PhD, Maciej Szydlowski, PhD, Emilia Bialopiotrowicz, PhD, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Anna Polak, MSc, Krzysztof Warzocha, MD PhD, Wojciech Czardybon, PhD, Michal Galezowski, PhD, Renata Windak, PhD, Aniela Golas, PhD, Krzysztof Brzozka, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 706.
https://doi.org/10.1182/blood.V126.23.706.706
Published: 2015
Journal Articles

Evaluation of TNF Superfamily Molecules Release by Neutrophils and B Leukemic Cells of Patients with Chronic B – Cell Lymphocytic Leukemia

Jolanta Sawicka-Powierza, Ewa Jablonska, Janusz Kloczko, Jaroslaw Piszcz, Marzena Garley, Wioletta Ratajczak-Wrona
Journal: Blood
Blood (2010) 116 (21): 4855.
https://doi.org/10.1182/blood.V116.21.4855.4855
Published: 2010