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Journal Articles

Immunoregulatory CD71 + Erythroid Cells (CECs) Expand in Multiple Myeloma and Impair Control of L. Monocytogenes Infection

Tomasz M. Grzywa, Karol Czubak, Karolina Sidor, Zofia Pilch, Aneta Bragiel-Pieczonka, Grazyna Hoser, Anna Rodziewicz-Lurzynska, Milena Małecka-Giełdowska, Joanna Barankiewicz, Filip Garbicz, Olga Ciepiela, Przemyslaw Juszczynski, Michal Wegrzynowicz, Tomasz Skirecki, Jakub Golab, Dominika Nowis

Blood (2022) 140 (Supplement 1): 12538–12539.

https://doi.org/10.1182/blood-2022-164577

Published: 2022

Journal Articles

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Blood (2022) 140 (Supplement 1): 4189–4190.

https://doi.org/10.1182/blood-2022-168770

Published: 2022

Journal Articles

Hypoxia Regulates the Immunoregulatory Properties of CD71 + Erythroid Cells

Tomasz M. Grzywa, Magdalena Justyniarska, Anna Sosnowska, Patrycja Szpak, Karol Czubak, Klaudyna Fidyt, Ilona Kalaszczynska, Milena Małecka-Giełdowska, Olga Ciepiela, Agnieszka Tomaszewska, Grzegorz W Basak, Jakub Golab, Dominika Nowis

Blood (2022) 140 (Supplement 1): 8166–8167.

https://doi.org/10.1182/blood-2022-157738

Published: 2022

Journal Articles

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Blood (2020) 136 (Supplement 1): 33–34.

https://doi.org/10.1182/blood-2020-134778

Published: 2020

Journal Articles

Pharmacological Induction of NOXA Sensitizes High-Risk B Cell Acute Lymphoblastic Leukemia Cells to Venetoclax

Klaudyna Fidyt, MSc, Julia Cyran, Agata Pastorczak, Nicholas T. Crump, Angelika Muchowicz, Agnieszka Goral, Krzysztof Domka, Lukasz Komorowski, Karolina Siudakowska, Agnieszka Graczyk-Jarzynka, Elzbieta Patkowska, Magdalena Winiarska, Jakub Golab, Thomas A. Milne, Malgorzata Firczuk, PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-139318

Published: 2020

Journal Articles

HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies

Blood (2017) 130 (14): 1628–1638.

https://doi.org/10.1182/blood-2016-08-736066

Published: 2017

Includes: Supplemental data

Journal Articles

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Anna Polak, MSc, Przemyslaw Kiliszek, MSc, Tomasz Sewastianik, MSc, Maciej Szydlowski, PhD, Ewa Jablonska, PhD, Emilia Bialopiotrowicz, PhD, Patryk Gorniak, PhD, Sergiusz Markowicz, PhD, Eliza Nowak, MSc, Monika A. Grygorowicz, MSc, Dominika Nowis, MDPhD, Jakub Golab, MD PhD, Sebastian Giebel, MD PhD, Ewa Lech-Maranda, MD PhD, Krzysztof Warzocha, MD PhD, Przemyslaw Juszczynski, MD PhD

Blood (2015) 126 (23): 4917.

https://doi.org/10.1182/blood.V126.23.4917.4917

Published: 2015

Journal Articles

Peroxiredoxins-1 and 2 Affect Proliferation and Survival of Lymphoma Cells

Malgorzata Firczuk, PhD, Anna Trzeciecka, MDStudent, Malgorzata Bajor, PhD, Angelika Muchowicz, PhD, Radoslaw Zagozdzon, MD PhD, Joanna Barankiewicz, MD, Antoni Domagala, MDStudent, Szymon Klossowski, M.Sc., Agata Malinowska, M.Sc., Justyna Chlebowska, M.Sc., Ryszard Ostaszewski, PhD, Jakub Golab, MD PhD, Dominika Nowis, MD, PhD

Blood (2014) 124 (21): 1693.

https://doi.org/10.1182/blood.V124.21.1693.1693

Published: 2014

Journal Articles

SK053, an Inhibitor of Enzymes Involved in Allosteric Disulfide Bonds Formation, Targets Expression of Histone Genes and Induces Differentiation of Human AML Cell

Justyna Chlebowska, M.Sc., Pawel Gaj, PhD, Piotr Stawinski, M.Sc., Michal Lazniewski, M.Sc., Malgorzata Firczuk, PhD, Karolina Furs, Radoslaw Sadowski, Szymon Klossowski, M.Sc., Ryszard Ostaszewski, PhD, Jakub Golab, MD PhD, Krzysztof Giannopoulos, MD PhD, Rafal Ploski, MD, PhD, Dominika Nowis, MD, PhD

Blood (2014) 124 (21): 3503.

https://doi.org/10.1182/blood.V124.21.3503.3503

Published: 2014

Journal Articles

HDAC Inhibitors As Potential New Agents Improving the Efficacy of Monoclonal Antibodies

Malgorzata Bobrowicz, MSc, Michal Dwojak, DMD, Agata Malenda, MD PhD, Kamil Bojarczuk, MSc, Marta Siernicka, MSc, Beata Pyrzynska, PhD, Ewa Lech-Maranda, MD PhD, Tomasz Stoklosa, MD PhD, Magdalena Winiarska, PhD, Jakub Golab, MD PhD

Blood (2014) 124 (21): 3641.

https://doi.org/10.1182/blood.V124.21.3641.3641

Published: 2014

Journal Articles

HDAC6 Inhibition Increases CD20 Level and Improves The Efficacy Of Anti-CD20 Monoclonal Antibodies

Malgorzata Bobrowicz, MSc, Michal Dwojak, Kamil Bojarczuk, MSc, Magdalena Winiarska, PhD, Jakub Golab, M.D., Ph.D.

Blood (2013) 122 (21): 4406.

https://doi.org/10.1182/blood.V122.21.4406.4406

Published: 2013

Journal Articles

SK053 An Inhibitor Of Enzymes Involved In Allosteric Disulfide Bonds Formation Induces Differentiation Of Human AML Cells

Justyna Chlebowska, M.Sc., Malgorzata Firczuk, Ph.D., Karolina Furs, Angelika Muchowicz, Ph.D., Radoslaw Sadowski, Adam D. Staruch, M.D., Szymon Klossowski, M.Sc., Ryszard Ostaszewski, Ph.D., Anna Paulina Dabrowska-Iwanicka, M.D., Ph.D., Jakub Golab, M.D., Ph.D., Dominika Nowis, M.D., Ph.D.

Blood (2013) 122 (21): 4215.

https://doi.org/10.1182/blood.V122.21.4215.4215

Published: 2013

Journal Articles

Inhibitors Of B-Cell Receptor Molecules Affect Surface CD20 and Impair Antitumor Activity Of Anti-CD20 Monoclonal Antibodies

Kamil Bojarczuk, MSc, Magdalena Winiarska, PhD, Malgorzata Bobrowicz, MSc, Michal Dwojak, Nina Miazek, Piotr Zapala, Dimitar G Efremov, MD, PhD, Jakub Golab, M.D., Ph.D.

Blood (2013) 122 (21): 4217.

https://doi.org/10.1182/blood.V122.21.4217.4217

Published: 2013

Journal Articles

Inhibitors Of Src Family and AKT Regulate The Activity Of CD20 Promoter

Beata Pyrzynska, PhD, Kamil Bojarczuk, MSc, Magdalena Winiarska, PhD, Jacek Bil, MD, PhD, Nina Miazek, Piotr Zapala, Malgorzata Bobrowicz, MSc, Michal Dwojak, Marta Siernicka, Jakub Golab, M.D., Ph.D.

Blood (2013) 122 (21): 1838.

https://doi.org/10.1182/blood.V122.21.1838.1838

Published: 2013

Journal Articles

Prenyl Transferases Are Involved in the Regulation of CD20 Levels and Influence Anti-CD20 Monoclonal Antibody-Mediated Activation of Complement-Dependent Cytotoxicity,

Dominika Nowis, MD, PhD, Magdalena Winiarska, PhD, Jacek Bil, MD, PhD, Angelika Muchowicz, MSc, Malgorzata Wanczyk, MSc, Eliza Glodkowska-Mrowka, MD, Kamil Bojarczuk, BSc, Malgorzata Firczuk, PhD, Ewa Wilczek, PhD, Malgorzata Wachowska, MSc, Justyna Chlebowska, MSc, Michal Dwojak, Marta Miaczynska, PhD, Tomasz Stoklosa, MD, PhD, Jakub Golab, MD, PhD

Blood (2011) 118 (21): 3722.

https://doi.org/10.1182/blood.V118.21.3722.3722

Published: 2011

Journal Articles

Sorafenib Affects Membrane Complement Inhibitors and Improves Antitumor Activity of Rituximab,

Jakub Golab, MD, PhD, Jacek Bil, MD, PhD, Kamil Bojarczuk, BSc, Dominika Nowis, MD, PhD, Marcin Okroj, Ph.D., Grzegorz Basak, MD, PhD, Tomasz Stoklosa, MD, PhD, Magdalena Winiarska, PhD

Blood (2011) 118 (21): 3723.

https://doi.org/10.1182/blood.V118.21.3723.3723

Published: 2011

Journal Articles

Src Family Tyrosine Kinases Are Involved in the Transcriptional Regulation of CD20 Levels

Magdalena Winiarska, PhD, Jacek Bil, MD, PhD, Kamil Bojarczuk, BSc, Dominika Nowis, MD, PhD, Malgorzata Wanczyk, MSc, Michal Dwojak, Grzegorz Basak, MD, PhD, Tomasz Stoklosa, MD, PhD, Jakub Golab, MD, PhD

Blood (2011) 118 (21): 1661.

https://doi.org/10.1182/blood.V118.21.1661.1661

Published: 2011

Journal Articles

Bortezomib modulates surface CD20 in B-cell malignancies and affects rituximab-mediated complement-dependent cytotoxicity

Jacek Bil, Magdalena Winiarska, Dominika Nowis, Kamil Bojarczuk, Anna Dąbrowska-Iwanicka, Grzegorz W. Basak, Kazimierz Sułek, Marek Jakobisiak, Jakub Golab

Blood (2010) 115 (18): 3745–3755.

https://doi.org/10.1182/blood-2009-09-244129

Published: 2010

Includes: Supplemental data

Journal Articles

Statins Impair Antitumor Effects of CD20 mAb by Inducing Conformational Changes of CD20.

Blood (2007) 110 (11): 2341.

https://doi.org/10.1182/blood.V110.11.2341.2341

Published: 2007

Journal Articles

A Combination of Retinoic Acid and Proteasome Inhibitors for the Treatment of Leukemias Is Potentially Dangerous

Cezary Wójcik, Izabella Młynarczuk, Graz˙yna Hoser, Jerzy Kawiak, Tomasz Stokłosa, Jakub Gołab, Sherwin Wilk

Blood (1999) 94 (5): 1827–1828.

https://doi.org/10.1182/blood.V94.5.1827

Published: 1999

NARROW

Immunoregulatory CD71 + Erythroid Cells (CECs) Expand in Multiple Myeloma and Impair Control of L. Monocytogenes Infection

Super-Enhancer-Driven PIM Kinase Upregulation in Multiple Myeloma Maintains the Plasma Cell-Specific Oncogenic and Microenvironmental Circuits, and Can be Efficiently Targeted By the Pan-PIM Inhibitor MEN1703

Hypoxia Regulates the Immunoregulatory Properties of CD71 + Erythroid Cells

Inhibition of PIM Kinases in Diffuse Large B-Cell Lymphoma Cells Targets MYC-Dependent Transcriptional Program, Increases CD20 Expression and Augments the Efficacy of Anti-CD20 Antibodies

Pharmacological Induction of NOXA Sensitizes High-Risk B Cell Acute Lymphoblastic Leukemia Cells to Venetoclax

HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies

MEK1 Inhibitor Selumetinib Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia Cells (B-ALL) to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

Peroxiredoxins-1 and 2 Affect Proliferation and Survival of Lymphoma Cells

SK053, an Inhibitor of Enzymes Involved in Allosteric Disulfide Bonds Formation, Targets Expression of Histone Genes and Induces Differentiation of Human AML Cell

HDAC Inhibitors As Potential New Agents Improving the Efficacy of Monoclonal Antibodies

HDAC6 Inhibition Increases CD20 Level and Improves The Efficacy Of Anti-CD20 Monoclonal Antibodies

SK053 An Inhibitor Of Enzymes Involved In Allosteric Disulfide Bonds Formation Induces Differentiation Of Human AML Cells

Inhibitors Of B-Cell Receptor Molecules Affect Surface CD20 and Impair Antitumor Activity Of Anti-CD20 Monoclonal Antibodies

Inhibitors Of Src Family and AKT Regulate The Activity Of CD20 Promoter

Prenyl Transferases Are Involved in the Regulation of CD20 Levels and Influence Anti-CD20 Monoclonal Antibody-Mediated Activation of Complement-Dependent Cytotoxicity,

Sorafenib Affects Membrane Complement Inhibitors and Improves Antitumor Activity of Rituximab,

Src Family Tyrosine Kinases Are Involved in the Transcriptional Regulation of CD20 Levels

Bortezomib modulates surface CD20 in B-cell malignancies and affects rituximab-mediated complement-dependent cytotoxicity

Statins Impair Antitumor Effects of CD20 mAb by Inducing Conformational Changes of CD20.

A Combination of Retinoic Acid and Proteasome Inhibitors for the Treatment of Leukemias Is Potentially Dangerous

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American Society of Hematology

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American Society of Hematology

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