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Elzbieta Patkowska
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Journal Articles

Correlation of Baseline Gene Mutations With Quizartinib Efficacy in Patients With FLT3 -ITD-Positive Newly Diagnosed Acute Myeloid Leukemia in the Phase 3 QuANTUM-First Trial

Mark J. Levis, Pau Montesinos, Hee-Je Kim, Radovan Vrhovac, Elzbieta Patkowska, Pavel Zak, Po-Nan Wang, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander E. Perl, Mitsuhiro Yazawa, Jaime E. Connolly Rohrbach, Venkat Thodima, Ken C. N. Chang, Li Liu, Karima Imadalou, Akash Nahar, Kristy Burns, Harry P. Erba
Journal: Blood
Blood (2024) 144 (Supplement 1): 848.
https://doi.org/10.1182/blood-2024-203303
Published: 2024
Journal Articles

A Polish Adult Leukemia Group (PALG) Prospective International Randomized Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) in Acute Myeloid Leukemia (AML) Patients ≤ 60 Years Old (PALG-AML1/2016) - Topline Results

Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Libura, Sebastian Giebel, Michał Soin, Damian Mikulski, Kacper Kościelny, Wojciech Fendler, Magdalena Czemerska, Agata Majchrzak, Anna Kopinska, Krzysztof Woźniczka, Martyna Włodarczyk, Karol Wójcik, Grzegorz Helbig, Małgorzata Raźny, Marta Sobas, Tomasz Wróbel, Donata Szymczak, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Edyta Cichocka, Janusz Hałka, Elzbieta Patkowska, Marzena Wątek, Jolanta Wozniak, Ewa Lech-Maranda, Agata Obara, Agnieszka Kopacz, Katarzyna Dulik, Grzegorz Charlinski, Jerzy Holowiecki, Andi Rustani, Ameenah Sukkur, Nuria Mencia-Trinchant, Pinkal Desai, Michael Samuel, Justin D. Kaner, Michal Bar-Natan, Jonathan Canaani, Ellen K. Ritchie, Monica L Guzman, Sylvie D Freeman, Gail J. Roboz
Journal: Blood
Blood (2024) 144 (Supplement 1): 970.
https://doi.org/10.1182/blood-2024-202365
Published: 2024
Journal Articles

Quantum-First: Effects of Quizartinib (Q) on RFS, OS, CIR, and MRD in Newly Diagnosed (nd) Patients (pts) with FMS-like Tyrosine Kinase 3-Internal Tandem Duplication-Positive ( FLT3 -ITD+) Acute Myeloid Leukemia (AML) Who Received Continuation (CONT) Therapy (tx)

Mark J. Levis, Harry Erba, Pau Montesinos, Elzbieta Patkowska, Jorge E. Cortes, Herve Dombret, Alexander E. Perl, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Li Liu, Yasser M. Mostafa Kamel, Karima Imadalou, Abderrahmane Laadem, Mikkael A. Sekeres, Kristy Burns
Journal: Blood
Blood (2024) 144 (Supplement 1): 2890.
https://doi.org/10.1182/blood-2024-207305
Published: 2024
Journal Articles

Safety and Efficacy Results from CLI120-001 a Phase 1 Study in RR-AML and HR-MDS: Update from Higher Dose Levels

Ewa Lech Marańda, Elżbieta Patkowska, Natalia Jakacka, Camille N. Abboud, Howard A. Burris, Scott R. Solomon, Noemi Angelosanto, Tomasz Rzymski, Peter Littlewood, Kamil Kuś, Agnieszka Sroka-Porada, Renata Dudziak, Hendrik Nogai, Axel Glasmacher, Terrence Bradley, Gautam Borthakur, Elie Mouhayar, Paweł Steckiewicz, Sylwia Kościółek- Zgódka, Agata Szymańska, Jan Maciej Zaucha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2913.
https://doi.org/10.1182/blood-2023-186620
Published: 2023
Journal Articles

Stratification Using ECOG, ADL and HCT-CI Scales, but Not CGA Enables Identifying Elderly AML Patients Fit for Intensive Chemotherapy - a Multicenter Study from Polish Adult Leukemia Group

Bozena Katarzyna Budziszewska, Michał Łomiak, Joanna Barankiewicz, Elzbieta Patkowska, Grzegorz Helbig, Lukasz Bolkun, Anna Irga-Staniukiewicz, Anna Kiżewska, Agnieszka Piekarska, Anna Koclęga, Agnieszka Pluta, Marta Kuydowicz, Sylwia Kościółek- Zgódka, Edyta Cichocka, Agata Malenda, Karol Wójcik, Tomasz Gromek, Piotr Małecki, Sebastian Grosicki, Agnieszka Wierzbowska, Ewa Lech-Maranda
Journal: Blood
Blood (2023) 142 (Supplement 1): 4218.
https://doi.org/10.1182/blood-2023-189713
Published: 2023
Journal Articles

Quantum-First Trial: FMS-like Tyrosine Kinase 3-Internal Tandem Duplication ( FLT3 -ITD)-Specific Measurable Residual Disease (MRD) Clearance Assessed through Induction (IND) and Consolidation (CONS) Is Associated with Improved Overall Survival (OS) in Newly Diagnosed (nd) FLT3 -ITD+ AML Patients (pts)

Alexander Perl, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E Rohrbach, Ken C N Chang, Li Liu, Yasser Mostafa Kamel, Karima Imadalou, Arnaud Lesegretain, Jorge Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F Schlenk, Mark J. Levis
Journal: Blood
Blood (2023) 142 (Supplement 1): 832.
https://doi.org/10.1182/blood-2023-186785
Published: 2023
Journal Articles

Pre-Transplant Multiparameter Flow Cytometric Measurable Residual Disease in Acute Myeloid Leukemia As an Independent Prognostic Factor for Survival after Myeloablative Allogeneic Hematopoietic Cell Transplantation

Anna Czyz, Malgorzata Maria Sobczyk Kruszelnicka, Tomasz Czerw, Sebastian Giebel, Magdalena Dutka, Agnieszka Piekarska, Maria Bieniaszewska, Jan Zaucha, Maciej Majcherek, Marta Anna Sobas, Tomasz Wróbel, Barbara Nasilowska-Adamska, Halaburda Kazimierz, Andrzej Szczepaniak, Lidia Gil, Anna Kopinska, Grzegorz Helbig, Sylwia Bartyzel-Palinska, Patrycja Mensah-Glanowska, Agnieszka Tomaszewska, Agnieszka Pluta, Elzbieta Patkowska, Jolanta Wozniak, Agnieszka Balana, Donata Szymczak, Jolanta Parulska, Ameenah Sukkur, Andi Rustani, Nuria Mencia Trinchant, Pinkal Desai, Michael Samuel, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz, Agnieszka Wierzbowska
Journal: Blood
Blood (2022) 140 (Supplement 1): 7747–7749.
https://doi.org/10.1182/blood-2022-167407
Published: 2022
Journal Articles

Prognostic Impact of Persistent Measurable Residual Disease in Patients with Acute Myeloid Leukemia FLT3+ Treated with Intensive Chemotherapy Plus Midostaurin - a Retrospective Study of the Polish Adult Leukemia Group (PALG)

Elzbieta Patkowska, Alicja Sadowska-Klasa, Jan Zaucha, Andrzej Szczepaniak, Lidia Gil, Lukasz Bolkun, Michal Gorka, Marta Antonina Libura, Renata Guzicka-Kazimierczak, Marta Anna Sobas, Anna Koclega, Jolanta Wozniak, Krzysztof Lewandowski, Iwona Solarska, Magdalena Wojtas, Aleksandra Leszczynska, Zuzanna Kandula, Edyta Subocz, Edyta Cichocka, Katarzyna Krawczyk, Dorota Hawrylecka, Agnieszka Pluta, Agnieszka Wierzbowska, Sebastian Giebel, Ewa Lech-Marańda
Journal: Blood
Blood (2022) 140 (Supplement 1): 11836–11837.
https://doi.org/10.1182/blood-2022-170126
Published: 2022
Journal Articles

Treatment and Disease Characteristics of Chronic Myeloid Leukemia in Blast Crisis: The European Leukemianet Blast Crisis Registry

Annamaria Brioli, Elza Lomaia, Christian Fabisch, Tomasz Sacha, Hana Klamová, Elena Morozova, Aleksandra Golos, Philipp Ernst, Ulla Olsson-Strömberg, Jiri Mayer, Franck E. Nicolini, Han Bao, Fausto Castagnetti, Elzbieta Patkowska, Klaus Hirschbühl, Edyta Paczkowska, Anne Parry, Astghik Voskanyan, Susanne Saussele, Georg-Nikolaus Franke, Alexander Kiani, Edgar Faber, Krzysztof Lewandowski, Stefan W. Krause, Elke Dammann, Peter Anhut, Justyna Gil, Thomas Südhoff, Sonja Heibl, Markus Pfirrmann, Andreas Hochhaus, Michael Lauseker
Journal: Blood
Blood (2022) 140 (Supplement 1): 818–820.
https://doi.org/10.1182/blood-2022-162252
Published: 2022
Journal Articles

Impact of Allogeneic Hematopoietic Cell Transplantation in First Complete Remission in Addition to FLT3 Inhibition with Quizartinib in Acute Myeloid Leukemia with FLT3 -Internal Tandem Duplication: Results from the Quantum-First Trial

Richard F. Schlenk, Pau Montesinos, Antonio Romero-Aguilar, Radovan Vrhovac, Elżbieta Patkowska, Hee-Je Kim, Pavel Zak, Po-Nan Wang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Aziz Benzohra, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Alexander E. Perl, Mark J. Levis, Harry P. Erba
Journal: Blood
Blood (2022) 140 (Supplement 1): 2130–2132.
https://doi.org/10.1182/blood-2022-169011
Published: 2022
Journal Articles

Prospective Assessment of Measurable Residual Disease Kinetics in Intensively Treated Patients with Acute Myeloid Leukemia - Results of the Polish Adult Leukemia Group PALG-AML1/2016 Study

Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Antonina Libura, Sebastian Giebel, Piotr Stelmach, Magdalena Czemerska, Piotr Strzałka, Anna Kopinska, Krzysztof Wozniczka, Grzegorz Helbig, Karol Wojcik, Malgorzata Razny, Marta Anna Sobas, Tomasz Wróbel, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Edyta Cichocka, Janusz Halka, Elzbieta Patkowska, Marzena Watek, Jolanta Wozniak, Ewa Lech-Marańda, Agnieszka Kopacz, Katarzyna Dulik, Jerzy Holowiecki, Michal Soin, Damian Mikulski, Ewelina Perdas, Wojciech Fendler, Ameenah Sukkur, Andi Rustani, Nuria Mencia Trinchant, Pinkal Desai, Sangmin Lee, Michael Samuel, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 6241–6243.
https://doi.org/10.1182/blood-2022-156950
Published: 2022
Journal Articles

A Polish Acute Leukemia Group Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in Acute Myeloid Leukemia (AML) Patients ≤ 60 Years Old (PALG-AML1/2016)

Agnieszka Wierzbowska, Anna Czyz, Agnieszka Pluta, Marta Antonina Libura, Sebastian Giebel, Piotr Stelmach, Magdalena Czemerska, Kinga Krawiec, Anna Kopinska, Krzysztof Wozniczka, Grzegorz Helbig, Janusz Halka, Marta Anna Sobas, Tomasz Wróbel, Andrzej Szczepaniak, Lidia Gil, Magdalena Dutka, Maria Bieniaszewska, Tomasz Gromek, Marek Hus, Elzbieta Patkowska, Marzena Watek, Ewa Lech-Marańda, Agnieszka Kopacz, Katarzyna Dulik, Jerzy Holowiecki, Agata Obara, Edyta Cichocka, Krzysztof Gawronski, Monika Mordak-Domagala, Ameenah Sukkur, Andi Rustani, Pinkal Desai, Michael Samuel, Nuria Mencia Trinchant, Sangmin Lee, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 9013–9015.
https://doi.org/10.1182/blood-2022-166184
Published: 2022
Journal Articles

Quantum-First Trial: FLT3 -ITD-Specific MRD Clearance Is Associated with Improved Overall Survival

Mark J. Levis, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E. Connolly Rohrbach, Ken CN Chang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander Perl
Journal: Blood
Blood (2022) 140 (Supplement 1): 546–548.
https://doi.org/10.1182/blood-2022-162739
Published: 2022
Journal Articles

Phase 3 trial of gilteritinib plus azacitidine vs azacitidine for newly diagnosed FLT3 mut+ AML ineligible for intensive chemotherapy

Clinical Trials & Observations
Eunice S. Wang, Pau Montesinos, Mark D. Minden, Je-Hwan Lee, Michael Heuser, Tomoki Naoe, Wen-Chien Chou, Kamel Laribi, Jordi Esteve, Jessica K. Altman, Violaine Havelange, Anne-Marie Watson, Carlo Gambacorti-Passerini, Elzbieta Patkowska, Shufang Liu, Ruishan Wu, Nisha Philipose, Jason E. Hill, Stanley C. Gill, Elizabeth Shima Rich, Ramon V. Tiu
Journal: Blood
Blood (2022) 140 (17): 1845–1857.
https://doi.org/10.1182/blood.2021014586
Published: 2022
Includes: Supplemental data
Journal Articles

Phase 3, Open-Label, Randomized Study of Gilteritinib and Azacitidine Vs Azacitidine for Newly Diagnosed FLT3 -Mutated Acute Myeloid Leukemia in Patients Ineligible for Intensive Induction Chemotherapy

Eunice S. Wang, Pau Montesinos, Mark D. Minden, Je-Hwan Lee, Michael Heuser, Tomoki Naoe, Wen-Chien Chou, Kamel Laribi, Jordi Esteve, Jessica K. Altman, Violaine Havelange, Anne-Marie Watson, Elzbieta Patkowska, Shufang Liu, Ruishan Wu, Nisha Philipose, Jason E. Hill, Stanley Gill, Elizabeth Shima Rich, Ramon V. Tiu
Journal: Blood
Blood (2021) 138 (Supplement 1): 700.
https://doi.org/10.1182/blood-2021-145379
Published: 2021
Journal Articles

The Prognostic Value of Early Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Treated with Intensive Chemotherapy - Preliminary Results of Polish Adult Leukemia Group PALG-AML1/2016 Study

Agnieszka Wierzbowska, Agnieszka Pluta, Anna Czyz, Marta Antonina Libura, Sebastian Giebel, Magdalena Czemerska, Piotr Stelmach, Michal Soin, Anna Kopinska, Krzysztof Wozniczka, Grzegorz Helbig, Marta Sobas, Tomasz Wróbel, Andrzej Szczepaniak, Lidia Gil, Karol Wojcik, Malgorzata Razny, Magdalena Dutka, Maria Bieniaszewska, Janusz Halka, Tomasz Gromek, Marek Hus, Elzbieta Patkowska, Jolanta Wozniak, Edyta Cichocka, Agata Obara, Agnieszka Kopacz, Katarzyna Dulik, Jerzy Holowiecki, Damian Mikulski, Ewelina Perdas, Wojciech Fendler, Nicole M. Cruz, Nuria Mencia-Trinchant, Pinkal Desai, Sangmin Lee, Michael B. Samuel, Justin D. Kaner, Ellen Ritchie, Monica L. Guzman, Gail J. Roboz
Journal: Blood
Blood (2021) 138 (Supplement 1): 3453.
https://doi.org/10.1182/blood-2021-153520
Published: 2021
Journal Articles

Results from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 302 Patients with Relapsed or Refractory (r/r) Acute Myeloid Leukemia after Intensive Chemotherapy (ASTRAL-2 Study)

Gail J. Roboz, Guillermo Sanz, Elizabeth A. Griffiths, Karen Yee, Hagop Kantarjian, Christian Recher, Michael T. Byrne, Elzbieta Patkowska, Hee-Je Kim, Xavier Thomas, Ine Moors, Wendy Stock, Arpad Illes, Pierre Fenaux, Yasushi Miyazaki, Takahiro Yamauchi, Casey L. O'Connell, Yong Hao, Harold N. Keer, Mohammad Azab, Hartmut Dohner
Journal: Blood
Blood (2021) 138 (Supplement 1): 2344.
https://doi.org/10.1182/blood-2021-147769
Published: 2021
Journal Articles

A Multicenter Prospective Study on Efficacy and Safety of Ponatinib in Patients with Chronic Myeloid Leukemia Resistant or Intolerant to Previous Therapy: A 3-Year Report

Tomasz Sacha, MDPhD, Elzbieta Szczepanek, Paulina Dumnicka, PhD, Joanna Gora-Tybor, MD PhD, Joanna Niesiobedzka-Krezel, MDPhD, Witold Prejzner, MD PhD, Ewa Wasilewska, MDPhD, Janusz Kloczko, MDPhD, Hanna Ciepluch, MD, Wioletta Makowska, MD, Elzbieta Patkowska, MD, Joanna Wasilewska, MD, Grazyna Bober, MD, Malgorzata Kopera, MDPhD, Ryszard Wichary, MD, Renata Kroll-Balcerzak, MDPhD, Tomasz Gromek, MDPhD, Malgorzata Wach, MDPhD, Anna Rudkowska-Kazanowska, MD, Magdalena Swiniarska, MD, Edyta Paczkowska, MDPhD, Ewa Medras, MD, Monika Joks, MD, Marta Oller, MD, Renata Kasza, MD, Aleksandra Kostyra, MD, Justyna Gil, MD, Olga Grzybowska-Izydorczyk, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-141523
Published: 2020
Journal Articles

A Polish Acute Leukemia Group Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in Acute Myeloid Leukemia (AML) Patients ≤ 60 Years Old (PALG-AML1/2016)

Agnieszka Wierzbowska, MDPhD, Agnieszka Pluta, MDPhD, Marta Antonina Libura, MDPhD, Anna Czyz, MDPhD, Sebastian Giebel, MDPhD, Piotr Stelmach, MDPhD, Magdalena Czemerska, MDPhD, Anna Kopinska, MD, Krzysztof Wozniczka, MDPhD, Grzegorz Helbig, MDPhD, Karol Wojcik, MD, Malgorzata Razny, MDPhD, Marta Sobas, MDPhD, Tomasz Wrobel, MDPhD, Andrzej Szczepaniak, MDPhD, Lidia Gil, MDPhD, Alicja Sadowska-Klasa, MD, Jan Zaucha, MDPhD, Tomasz Gromek, MDPhD, Marek Hus, MDPhD, Edyta Cichocka, MDPhD, Janusz Halka, MDPhD, Elzbieta Patkowska, Jolanta Wozniak, PhD, Agata Obara, MD, Beata Blajer-Olszewska, MD, Katarzyna Dulik, MD, Jerzy Holowiecki, MDPhD, Michal Soin, M.Sc., Tadeusz Robak, MDPhD, Nicole M. Cruz, MD, Nuria Mencia-Trinchant, PhD, Pinkal Desai, MDMPH, Sangmin Lee, MD, Michael B. Samuel, MD, Justin D. Kaner, MD, Ellen Ritchie, MD, Monica L. Guzman, PhD, Gail J. Roboz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-140694
Published: 2020
Journal Articles

Pharmacological Induction of NOXA Sensitizes High-Risk B Cell Acute Lymphoblastic Leukemia Cells to Venetoclax

Klaudyna Fidyt, MSc, Julia Cyran, Agata Pastorczak, Nicholas T. Crump, Angelika Muchowicz, Agnieszka Goral, Krzysztof Domka, Lukasz Komorowski, Karolina Siudakowska, Agnieszka Graczyk-Jarzynka, Elzbieta Patkowska, Magdalena Winiarska, Jakub Golab, Thomas A. Milne, Malgorzata Firczuk, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-139318
Published: 2020