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Peter Littlewood
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Journal Articles

Safety and Efficacy Results from CLI120-001 a Phase 1 Study in RR-AML and HR-MDS: Update from Higher Dose Levels

Ewa Lech Marańda, Elżbieta Patkowska, Natalia Jakacka, Camille N. Abboud, Howard A. Burris, Scott R. Solomon, Noemi Angelosanto, Tomasz Rzymski, Peter Littlewood, Kamil Kuś, Agnieszka Sroka-Porada, Renata Dudziak, Hendrik Nogai, Axel Glasmacher, Terrence Bradley, Gautam Borthakur, Elie Mouhayar, Paweł Steckiewicz, Sylwia Kościółek- Zgódka, Agata Szymańska, Jan Maciej Zaucha
Journal: Blood
Blood (2023) 142 (Supplement 1): 2913.
https://doi.org/10.1182/blood-2023-186620
Published: 2023
Journal Articles

Multiomics Analysis Confirms Effective Target Engagement for RVU120 - a First-in-Class CDK8/19 Kinase Inhibitor in AML and MR-MDS Patients and Reveals the Mechanism of Action

Tomasz Rzymski, Agnieszka Sroka-Porada, Magdalena Kozakowska, Urszula Głowniak-Kwitek, Karolina Bukowska-Strakova, Marta Obacz, Peter Littlewood, Kamil Kuś, Kristina Goller, Kinga Kęska, Urszula Pakulska, Kamila Kozłowska-Tomczyk, Monika Madej, Milena Mazan, Przemyslaw Juszczynski, Jan M. Zaucha, Agnieszka Zarzycka, Noemi Angelosanto, Hendrik Nogai, Krzysztof Brzózka
Journal: Blood
Blood (2022) 140 (Supplement 1): 5939–5940.
https://doi.org/10.1182/blood-2022-168906
Published: 2022
Journal Articles

CDK 8/19 Kinase Inhibitor RVU120 in Patients with AML or Higher-Risk MDS: Safety and Efficacy Results from New Dose Escalation Cohorts

Camille Abboud, Sr., Jan Maciej Zaucha, Scott R. Solomon, Terrence Bradley, Elie Mouhayar, Noemi Angelosanto, Hendrik Nogai, Renata Dudziak, Tomasz Rzymski, Peter Littlewood, Krzysztof Brzózka, Axel Glasmacher, Gautam Borthakur, Howard A. Burris, Sr., Ewa Lech Marańda
Journal: Blood
Blood (2022) 140 (Supplement 1): 6228–6229.
https://doi.org/10.1182/blood-2022-163150
Published: 2022
Journal Articles

CLI120-001 Phase Ib Study of RVU120(SEL120) in Patients with AML and High Risk MDS: Updated Safety/Efficacy Results from Initial Dose Escalation

Camille Abboud, Sr., Gautam Borthakur, Scott R. Solomon, Howard A. Burris, Sr., Terrence Bradley, JAN Maciej Zaucha, Sr., Ewa Lech-Marańda, Krzysztof Brzozka, Tomasz Rzymski, Peter Littlewood, Elie Mouhayar, Setareh Shamsili, Noemi Angelosanto
Journal: Blood
Blood (2021) 138 (Supplement 1): 3418.
https://doi.org/10.1182/blood-2021-151030
Published: 2021