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Pavel Zak
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Journal Articles

Complications of Modern Immunotherapy (CAR-T and BsAb), a Single Centre Experience

Tereza Sokolova, Alzbeta Zavrelova, David Belada, Pavel Zak, Jakub Radocha
Journal: Blood
Blood (2024) 144 (Supplement 1): 6957.
https://doi.org/10.1182/blood-2024-193235
Published: 2024
Journal Articles

Correlation of Baseline Gene Mutations With Quizartinib Efficacy in Patients With FLT3 -ITD-Positive Newly Diagnosed Acute Myeloid Leukemia in the Phase 3 QuANTUM-First Trial

Mark J. Levis, Pau Montesinos, Hee-Je Kim, Radovan Vrhovac, Elzbieta Patkowska, Pavel Zak, Po-Nan Wang, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander E. Perl, Mitsuhiro Yazawa, Jaime E. Connolly Rohrbach, Venkat Thodima, Ken C. N. Chang, Li Liu, Karima Imadalou, Akash Nahar, Kristy Burns, Harry P. Erba
Journal: Blood
Blood (2024) 144 (Supplement 1): 848.
https://doi.org/10.1182/blood-2024-203303
Published: 2024
Journal Articles

Quantum-First Trial: FMS-like Tyrosine Kinase 3-Internal Tandem Duplication ( FLT3 -ITD)-Specific Measurable Residual Disease (MRD) Clearance Assessed through Induction (IND) and Consolidation (CONS) Is Associated with Improved Overall Survival (OS) in Newly Diagnosed (nd) FLT3 -ITD+ AML Patients (pts)

Alexander Perl, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E Rohrbach, Ken C N Chang, Li Liu, Yasser Mostafa Kamel, Karima Imadalou, Arnaud Lesegretain, Jorge Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F Schlenk, Mark J. Levis
Journal: Blood
Blood (2023) 142 (Supplement 1): 832.
https://doi.org/10.1182/blood-2023-186785
Published: 2023
Journal Articles

Real World Population- Based Data from Nationwide Registry Support the Existence of Accelerated Phase in Newly Diagnosed Chronic Myeloid Leukemia (CML) Patients Even in Tyrosine Kinase Inhibitors (TKIs) Era

Tomas Hornak, Jiri Mayer, Petra Cicatkova, Lukas Semerad, Anezka Kvetkova, Hana Klamova, Edgar Faber, Petra Belohlavkova, Michal Karas, Lukas Stejskal, Eduard Cmunt, Olga Cerna, Dana Srbova, Hana Zizkova, Lucia Vrablova, Ivana Skoumalova, Jaroslava Voglova, Tereza Jurkova, Marika Chrapava, Tomas Jurcek, Ivana Jeziskova, Marie Jarosova, Katerina Machova Polakova, Tomas Papajik, Pavel Zak, Pavel Jindra, Daniela Zackova
Journal: Blood
Blood (2023) 142 (Supplement 1): 3166.
https://doi.org/10.1182/blood-2023-174455
Published: 2023
Journal Articles

Impact of Allogeneic Hematopoietic Cell Transplantation in First Complete Remission in Addition to FLT3 Inhibition with Quizartinib in Acute Myeloid Leukemia with FLT3 -Internal Tandem Duplication: Results from the Quantum-First Trial

Richard F. Schlenk, Pau Montesinos, Antonio Romero-Aguilar, Radovan Vrhovac, Elżbieta Patkowska, Hee-Je Kim, Pavel Zak, Po-Nan Wang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Aziz Benzohra, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Alexander E. Perl, Mark J. Levis, Harry P. Erba
Journal: Blood
Blood (2022) 140 (Supplement 1): 2130–2132.
https://doi.org/10.1182/blood-2022-169011
Published: 2022
Journal Articles

Quantum-First Trial: FLT3 -ITD-Specific MRD Clearance Is Associated with Improved Overall Survival

Mark J. Levis, Harry P. Erba, Pau Montesinos, Radovan Vrhovac, Elzbieta Patkowska, Heeje Kim, Pavel Zak, Po-Nan Wang, Jaime E. Connolly Rohrbach, Ken CN Chang, James Hanyok, Li Liu, Yasser Mostafa Kamel, Arnaud Lesegretain, Jorge E. Cortes, Mikkael A. Sekeres, Hervé Dombret, Sergio Amadori, Jianxiang Wang, Richard F. Schlenk, Alexander Perl
Journal: Blood
Blood (2022) 140 (Supplement 1): 546–548.
https://doi.org/10.1182/blood-2022-162739
Published: 2022
Journal Articles

Remission and Survival after Single Versus Double Induction with 7+3 for Newly Diagnosed Acute Myeloid Leukemia: Results from the Planned Interim Analysis of Randomized Controlled SAL-Daunodouble Trial

Christoph Röllig, MD MSC, Björn Steffen, MD, Nael Alakel, MD, Regina Herbst, MD, Richard Noppeney, MD, Maher Hanoun, MD PhD, Zdenek Racil, MD PhD, Kerstin Schäfer-Eckart, MD, Alwin Krämer, MD, Andreas Neubauer, Professor Dr, Claudia D Baldus, MD, Christoph Schliemann, Prof., MD, Martin Kaufmann, MD, Jolana Mertova, Edgar Jost, Dirk Niemann, MD, Jan Novak, Stefan W Krause, Sebastian Scholl, Gerhard Held, Professor Dr, Stefani B. Parmentier, Tomáš Szotkowski, MD PhD, Pavel Zak, MD, Andreas Rank, PD Dr, Maxi Wass, MD, Sebastian Buske, Michael Kramer, Frank Fiebig, Annett Haake, Johannes Schetelig, MDMSc, Uwe Platzbecker, Christian Thiede, MD, Carsten Müller-Tidow, MD, Wolfgang E. Berdel, Prof., MD, Hubert Serve, MD PhD, Gerhard Ehninger, MD, Jiri Mayer, Martin Bornhäuser, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–3.
https://doi.org/10.1182/blood-2020-140246
Published: 2020
Journal Articles

Serum Levels of Selected Cytokines in B-Cell Precursor Acute Lymphoblastic Leukemia and Their Association with Prognostic Factors and Survival

Jan M Horacek, MD PhD, Tomas Kupsa, MD PhD, Jan Vanek, PhD, Ladislav Jebavy, MD PhD, Pavel Zak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5078.
https://doi.org/10.1182/blood-2019-122667
Published: 2019
Journal Articles

The Influence of FLT3-ITD Mutation on Baseline Levels of Selected Cytokines and Soluble Adhesion Molecules in Acute Myeloid Leukemia with Mutated NPM-1

Tomas Kupsa, MD PhD, Jan M Horacek, MD PhD, Ladislav Jebavy, MD PhD, Pavel Zak, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5111.
https://doi.org/10.1182/blood-2019-126433
Published: 2019
Journal Articles

Impact of Comorbidities and Concomitant Medications on Survival of Patients with Chronic Lymphocytic Leukemia: Analysis of an Unselected Patient Population from East Bohemia

Pavel Vodarek, MD, Denisa Zeberova, Martin Simkovic, MD PhD, Monika Motyckova, MD PhD, David Belada, MD PhD, Pavel Žák, MD PhD, Lukas Smolej, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5328.
https://doi.org/10.1182/blood.V130.Suppl_1.5328.5328
Published: 2017
Journal Articles

Maintenance Therapy with Blinatumomab in Adults with Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (ALL): Overall Survival in Adults Enrolled in a Phase 3 Open-Label Trial

Alessandro Rambaldi, MD Prof, Françoise Rigal-Huguet, MD, Pavel Zak, Paul Cannell, MD, Kun Nie, PhD, Zachary F. Zimmerman, MD PhD, Max S. Topp, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2552.
https://doi.org/10.1182/blood.V130.Suppl_1.2552.2552
Published: 2017
Journal Articles

Characteristics and Outcome of Patients with Acute Myeloid Leukemia and t(6;9)(p22;q34)

Sabine Kayser, MD, Robert K. Hills, DPhil, Marlise R. Luskin, MD, Andrew M. Brunner, MD, Carole Shaw, Joerg Westermann, MD, Kamal Menghrajani, MD, Maria R. Baer, MD, Michelle A. Elliott, MD, Alexander E. Perl, MD, Christine Terré, PharmD, PhD, Zdenek Racil, MD, Jiri Mayer, Prof, MD SCs, Pavel Zak, MD, Tomas Szotkowski, MD, David Grimwade, Karin Mayer, MD, Roland B. Walter, MD PhD, Alwin Krämer, MD, Alan K. Burnett, MD, Anthony D. Ho, Richard M. Stone, MD, Martin S. Tallman, MD, Elihu H. Estey, MD, Carsten Müller-Tidow, Nigel H. Russell, Richard F. Schlenk, MD, Mark J. Levis, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3906.
https://doi.org/10.1182/blood.V130.Suppl_1.3906.3906
Published: 2017
Journal Articles

Simple Prognostic Score for Evaluation of Elderly Multiple Myeloma Patients

Jakub Radocha, MD PhD, Pavel Zak, MD PhD, Katerina Machalkova, MD, Katerina Beranova, MD, Jiri Hanousek, MD, Vladimír Maisnar, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5679.
https://doi.org/10.1182/blood.V128.22.5679.5679
Published: 2016
Journal Articles

Serum Levels of Cytokines and Cytokine Receptors Are Associated with Outcome in Newly Diagnosed AML Patients

Tomas Kupsa, MD, Jan Vanek, PhD, Pavel Zak, MD PhD, Ladislav Jebavy, Prof., MD, Jan M. Horacek, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5246.
https://doi.org/10.1182/blood.V128.22.5246.5246
Published: 2016
Journal Articles

Stem Cell Mobilization after Various Induction Regimens in Patients with Multiple Myeloma

Jakub Radocha, MD PhD, Vladimir Maisnar, MD PhD, Miriam Lanska, MD, Jiri Hanousek, MD, Katerina Machalkova, MD, Katerina Beranova, MD, Alzbeta Zavrelova, MD, Monika Motyckova, MD PhD, Pavel Zak, MD PhD
Journal: Blood
Blood (2015) 126 (23): 5433.
https://doi.org/10.1182/blood.V126.23.5433.5433
Published: 2015
Journal Articles

Comparison of Glucose and Lipid Metabolism Abnormality during Nilotinib, Imatinib and Dasatinib Therapy – Results of Enigma 2 Study

Racil Zdenek, Petra Belohlavkova, Petr Cetkovsky, Edgar Faber, Hana Klamova, Malaskova Ludmila, Tomasz Sacha, MD PhD, Voglova Jaroslava, Daniela Zackova, Pavel Zak, Jiri Mayer
Journal: Blood
Blood (2014) 124 (21): 1813.
https://doi.org/10.1182/blood.V124.21.1813.1813
Published: 2014
Journal Articles

Serum Profile Of Multiple Cytokines and Adhesion Molecules In Newly Diagnosed AML Patients Differs In Those Who Did Not Reach Complete Remission After Anthracycline/Cytarabine Induction Therapy

Tomas Kupsa, MD, Jan M Horacek, Assoc. Prof., MD, PhD, Martina Vasatova, PhD, Ladislav Jebavy, Prof., MD, PhD, Pavel Zak, Assoc. Prof., MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4997.
https://doi.org/10.1182/blood.V122.21.4997.4997
Published: 2013
Journal Articles

Evaluation Of Serum Cytokine and Adhesion Molecule Profile In Newly Diagnosed Acute Leukemias Using Biochip Array Technology

Jan M Horacek, Assoc. Prof., MD, PhD, Tomas Kupsa, MD, Martina Vasatova, PhD, Ladislav Jebavy, Prof., MD, PhD, Pavel Zak, Assoc. Prof., MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4975.
https://doi.org/10.1182/blood.V122.21.4975.4975
Published: 2013
Journal Articles

Rituximab and High-Dose Dexamethasone (R-dex) Is Effective In The Treatment Of Relapsed/Refractory Chronic Lymphocytic Leukemia

Martin Simkovic, M.D., David Belada, M.D., Ph.D., Monika Motyckova, M.D., Lukas Smolej, MD, PhD, Pavel Zak, Assoc. Prof., MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4184.
https://doi.org/10.1182/blood.V122.21.4184.4184
Published: 2013
Journal Articles

The Detection of Viral Infection in Bronchoalveolar Lavage Samples Collected From Recipients of Allogeneic Haematological Stem Cell Transplantation with Pneumonia (A 3 Year Epidemiological Study 2008–2010)

Eva Stepanova, Jr., MD, Pavel Zak, MD, PhD, Alzbeta Zavrelova, MD, Melanie Cermanova, MD, PHD, Jakub Radocha, MD, Lenka Pliskova, Sr., MD, Vlasta Stepanova, MD, Lukas Smolej, M.D., Ph.D.
Journal: Blood
Blood (2011) 118 (21): 4577.
https://doi.org/10.1182/blood.V118.21.4577.4577
Published: 2011