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Casey L. O'Connell
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Journal Articles

Characterizing Thrombotic Risk in TEMPI Syndrome: A Retrospective Case Series

Graham Blake Parker, Justin Cheng, Louis Terriou, Johanna Strobl, Ayesha Iftikhar, Davide Nappi, Meng Pan, Pierre-Yves Sansen, Elisa Diral, Elena Maria Elli, Wilfried A Schroyens, David B. Sykes, Casey L. O'Connell, Caitlin M O'Neill
Journal: Blood
Blood (2024) 144 (Supplement 1): 5551.
https://doi.org/10.1182/blood-2024-199861
Published: 2024
Journal Articles

Phase 1/2 Study of TP-3654, a Selective PIM1 Kinase Inhibitor: Preliminary Data Showed Clinical Activity and Cytokine Reductions in Relapsed/Refractory Myelofibrosis Patients

Lindsay A.M Rein, Firas El Chaer, Junichiro Yuda, Kazuya Shimoda, James McCloskey, Akiyoshi Takami, Tamanna Haque, Michiko Ichii, Shuichi Shirane, Masafumi Fukaya, Joseph M. Scandura, Terrence Bradley, Pankit Vachhani, Takayuki Tabayashi, Steven Green, Stanley Cheung, Prithviraj Bose, Sharad Khurana, Casey L. O'Connell, Idoroenyi Amanam, David M. Ross, Sujan Kabir, Masataka Seki, Mark Wade, Vishnu Peddagali, Zhonggai Li, Jatin Shah, Raajit K. Rampal
Journal: Blood
Blood (2023) 142 (Supplement 1): 626.
https://doi.org/10.1182/blood-2023-180164
Published: 2023
Journal Articles

Reclassification of Ascertain (ASTX727-02) Myelodysplastic Syndrome (MDS) Patients: Outcomes Including Clinical Response, Overall Survival (OS), and Leukemia Free Survival (LFS) Based on IPSS-R and IPSS-M Scoring Systems

Guillermo Garcia-Manero, James McCloskey, Elizabeth A. Griffiths, Amer M. Zeidan, Karen W.L. Yee, Aref Al-Kali, H. Joachim Deeg, Prapti A. Patel, Mitchell Sabloff, Mary-Margaret Keating, Nancy Zhu, Nashat Y. Gabrail, Salman Fazal, Joseph J. Maly, Olatoyosi Odenike, Hagop M. Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Rena Buckstein, Harsh Amin, Jasleen K. Randhawa, Brian Leber, Shannon Lee, Winny Chan, Sonia Souza, Yuri Sano, Harold N. Keer, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 4619.
https://doi.org/10.1182/blood-2023-188258
Published: 2023
Journal Articles

Analysis of ASXL1 Mutated T Cells in Patients with Myeloid Malignancies

Eduardo Fernandez, Jesse Sanchez, Gangning Liang, Mateusz Pospiech, Hongtao Li, Zarko Manojlovic, Houda Alachkar, Casey L. O'Connell
Journal: Blood
Blood (2023) 142 (Supplement 1): 6453.
https://doi.org/10.1182/blood-2023-173451
Published: 2023
Journal Articles

Long-Term Follow-up and T Cell Characteristics of Patients with ASXL1 -Mutated Relapsed or Refractory MDS or CMML Treated with Guadecitabine and Atezolizumab

Casey L. O'Connell, Maria R. Baer, Vu H. Duong, Andreas Due Ørskov, Jakob Werner Hansen, Sunil Kumar Saini, Denice Tsao-Wei, Justin Cheng, Peter A. Jones, Kirsten Grønbæk
Journal: Blood
Blood (2023) 142 (Supplement 1): 1883.
https://doi.org/10.1182/blood-2023-189486
Published: 2023
Journal Articles

Prolonged Survival in Bi-Allelic TP53 -Mutated ( TP53 mut) MDS Subjects Treated with Oral Decitabine/Cedazuridine in the Ascertain Trial (ASTX727-02)

Michael R. Savona, James K McCloskey, Elizabeth A. Griffiths, Karen Yee, Amer M. Zeidan, Aref Al-Kali, Joachim Deeg, Prapti Patel, Mitchell Sabloff, Mary-Margaret Keating, Kim-Hien Dao, Nancy Zhu, Nashat Y. Gabrail, Salman Fazal, Joseph J. Maly, Olatoyosi Odenike, Hagop Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Rena Buckstein, Harshad Amin, Jasleen K. Randhawa, Brian Leber, Aram Oganesian, Winny Chan, Yong Hao, Mohammad Azab, Guillermo Garcia-Manero
Journal: Blood
Blood (2022) 140 (Supplement 1): 2066–2069.
https://doi.org/10.1182/blood-2022-163841
Published: 2022
Journal Articles

Clinicopathological Features of Isolated Thrombocytopenia Associated with SRSF2 Mutations: A Case Series

Nneka Nwachukwu, Casey L. O'Connell, Maria Vergara-Lluri, Ashley Hagiya, Caitlin O'Neill
Journal: Blood
Blood (2022) 140 (Supplement 1): 11412–11413.
https://doi.org/10.1182/blood-2022-170439
Published: 2022
Journal Articles

Exploratory Predictors for Hydroxyurea Treatment Duration in Polycythemia Vera: A Retrospective Multi-Institutional Database Analysis

Chen Zhang, Douglas Tremblay, John Magnotti, Lukas Ronner, Nikolai A. Podoltsev, Jason Gotlib, Mark L. Heaney, Andrew Kuykendall, Casey L. O'Connell, Angela G Fleischman, Ruben Mesa, Abdulraheem Yacoub, John Mascarenhas, Jamile M. Shammo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9693–9695.
https://doi.org/10.1182/blood-2022-157873
Published: 2022
Journal Articles

A randomized phase 3 trial of interferon-α vs hydroxyurea in polycythemia vera and essential thrombocythemia

Clinical Trials & Observations
John Mascarenhas, Heidi E. Kosiorek, Josef T. Prchal, Alessandro Rambaldi, Dmitriy Berenzon, Abdulraheem Yacoub, Claire N. Harrison, Mary Frances McMullin, Alessandro M. Vannucchi, Joanne Ewing, Casey L. O'Connell, Jean-Jacques Kiladjian, Adam J. Mead, Elliott F. Winton, David S. Leibowitz, Valerio De Stefano, Murat O. Arcasoy, Craig M. Kessler, Rosalind Catchatourian, Damiano Rondelli, Richard T. Silver, Andrea Bacigalupo, Arnon Nagler, Marina Kremyanskaya, Max F. Levine, Juan E. Arango Ossa, Erin McGovern, Lonette Sandy, Mohamad E. Salama, Vesna Najfeld, Joseph Tripodi, Noushin Farnoud, Alexander V. Penson, Rona Singer Weinberg, Leah Price, Judith D. Goldberg, Tiziano Barbui, Roberto Marchioli, Gianni Tognoni, Raajit K. Rampal, Ruben A. Mesa, Amylou C. Dueck, Ronald Hoffman
Journal: Blood
Blood (2022) 139 (19): 2931–2941.
https://doi.org/10.1182/blood.2021012743
Published: 2022
Includes: Supplemental data
Journal Articles

Oral Decitabine/Cedazuridine in Patients with Lower Risk Myelodysplastic Syndrome: A Longer-Term Follow-up of from the Ascertain Study

Guillermo Garcia-Manero, James K McCloskey, Elizabeth A. Griffiths, Karen Yee, Amer M. Zeidan, Aref Al-Kali, H. Joachim Deeg, Prapti Patel, Mitchell Sabloff, Mary-Margaret Keating, Kim-Hien Dao, Nancy Zhu, Nashat Y. Gabrail, Salman Fazal, Joseph Maly, Olatoyosi Odenike, Hagop Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Richard A. Wells, Harshad Amin, Jasleen K. Randhawa, Brian Leber, Yong Hao, Harold N. Keer, Mohammad Azab, Michael R. Savona
Journal: Blood
Blood (2021) 138 (Supplement 1): 66.
https://doi.org/10.1182/blood-2021-144648
Published: 2021
Journal Articles

Results from a Global Randomized Phase 3 Study of Guadecitabine (G) Vs Treatment Choice (TC) in 302 Patients with Relapsed or Refractory (r/r) Acute Myeloid Leukemia after Intensive Chemotherapy (ASTRAL-2 Study)

Gail J. Roboz, Guillermo Sanz, Elizabeth A. Griffiths, Karen Yee, Hagop Kantarjian, Christian Recher, Michael T. Byrne, Elzbieta Patkowska, Hee-Je Kim, Xavier Thomas, Ine Moors, Wendy Stock, Arpad Illes, Pierre Fenaux, Yasushi Miyazaki, Takahiro Yamauchi, Casey L. O'Connell, Yong Hao, Harold N. Keer, Mohammad Azab, Hartmut Dohner
Journal: Blood
Blood (2021) 138 (Supplement 1): 2344.
https://doi.org/10.1182/blood-2021-147769
Published: 2021
Journal Articles

A Phase 1 Study Evaluating ASTX727 (decitabine and cedazuridine) and Venetoclax Combination Therapy in Newly Diagnosed AML Patients Unfit for Intensive Induction Chemotherapy

Gabriel N. Mannis, Elizabeth A. Griffiths, Michael R. Savona, Olatoyosi Odenike, Gail J. Roboz, Casey L. O'Connell, Jacqueline Dillingham, Prieya Wason, Lixia Zhu, Danna Chan, Harold N. Keer, Aram Oganesian, Kim-Hien Dao, Courtney D. DiNardo
Journal: Blood
Blood (2021) 138 (Supplement 1): 1245.
https://doi.org/10.1182/blood-2021-146264
Published: 2021
Journal Articles

Efficacy of Oral Decitabine/Cedazuridine (ASTX727) in the CMML Subgroup from the Ascertain Phase 3 Study

Michael R. Savona, James K McCloskey, Elizabeth A. Griffiths, Karen Yee, Amer M. Zeidan, Aref Al-Kali, H. Joachim Deeg, Prapti Patel, Mitchell Sabloff, Mary-Margaret Keating, Kim-Hien Dao, Nancy Zhu, Nashat Gabrail, Salman Fazal, Joseph Maly, Olatoyosi Odenike, Hagop Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Richard A. Wells, Harshad Amin, Jasleen K. Randhawa, Brian Leber, Yong Hao, Harold N. Keer, Mohammad Azab, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 3682.
https://doi.org/10.1182/blood-2021-154179
Published: 2021
Journal Articles

European Leukemianet (ELN) Response Predicts Disease Progression but Not Thrombosis or Death in Polycythemia Vera (PV): An Analysis of a Multicenter Database

Douglas Tremblay, Andrew Srisuwananukorn, Lukas Ronner, Nikolai Podoltsev, Jason Gotlib, Mark L. Heaney, Andrew T. Kuykendall, Casey L. O'Connell, Jamile M. Shammo, Angela Fleischman, Ruben A. Mesa, Abdulraheem Yacoub, Ronald Hoffman, Erin Moshier, Nicole Zubizarreta, John Mascarenhas
Journal: Blood
Blood (2021) 138 (Supplement 1): 240.
https://doi.org/10.1182/blood-2021-148020
Published: 2021
Journal Articles

Clinical Features of Idiopathic Erythrocytosis in a Racially Diverse Population

Caitlin O'Neill, MD, Ah-Reum Jeong, MD, Ibrahim Syed, Casey L. O'Connell, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-141372
Published: 2020
Journal Articles

The Role of D-Dimer for Optimal Thromboprophylaxis Strategy in Patients with COVID-19

Lantarima Bhoopat, MD, Anastasia Martynova, MD, April Choi, MD, Pattharawin Pattharanitima, MD, Semi Han, MD, Senxi Du, Ibrahim Syed, Catherine Chan, PharmD, Caitlin O'Neill, MD, Esther Oh, PharmD, Casey L. O'Connell, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-141732
Published: 2020
Journal Articles

A Pilot/Safety Study of sEphB4-Hsa in Combination with a Hypomethylating Agent for Patients with Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia Previously Treated with a Hypomethylating Agent

Caitlin O'Neill, MD, Akil Merchant, MD, Parkash S. Gill, MD, Casey L. O'Connell, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-141340
Published: 2020
Journal Articles

Clinical Efficacy and Safety of Oral Decitabine/Cedazuridine in 133 Patients with Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)

Michael R. Savona, MD, James K. McCloskey, MD, Elizabeth A. Griffiths, MD, Karen W.L. Yee, MD, Aref Al-Kali, MD, Amer M. Zeidan, MBBS, MHS, H. Joachim Deeg, MD, Prapti A. Patel, MD, Mitchell Sabloff, MSc,MDFRCPC, Mary-Margaret Keating, MD FRCPC, Kim-Hien Dao, DO, PhD, Nancy Zhu, MD, Nashat Gabrail, MD, Salman Fazal, MD, Joseph Maly, MD, Olatoyosi Odenike, MD, Hagop M. Kantarjian, MD, Amy E. DeZern, MD, Casey L. O'Connell, MD, Gail J. Roboz, MD, Lambert Busque, MD, Richard A. Wells, MD DPhil, Harshad Amin, MD, Jasleen K. Randhawa, MD, Brian Leber, MD, Yong Hao, MD PhD, Harold N. Keer, MDPhD, Mohammad Azab, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-133855
Published: 2020
Journal Articles

Improving Understanding of MDS Using an Animated Patient's Guide to Benefit Patient Health Outcomes

David A. Sallman, MD, Tracey Iraca, Casey L. O'Connell, MD, Rafael Bejar, MD PhD, Sandra Kurtin, ANP
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-134647
Published: 2020
Journal Articles

Results from a Phase 2 Study of Navitoclax in Combination with Ruxolitinib in Patients with Primary or Secondary Myelofibrosis

Claire N Harrison, Professor, Jacqueline S Garcia, MD, Ruben A Mesa, MD, Tim CP Somervaille, MD PhD, Rami S. Komrokji, MD, Naveen Pemmaraju, MD, Catriona Jamieson, MD PhD, Nikolaos Papadantonakis, MDPhDMSc, James M. Foran, MD, Casey L. O'Connell, MD, Leanne Holes, BS, MBA,, Jia Jia, PhD MBA, Jason Harb, PhD, Jessica Hutti, PhD, Josef T. Prchal, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 671.
https://doi.org/10.1182/blood-2019-130158
Published: 2019