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Journal Articles

Cytokine Modulation Correlates Strongly with Symptom Improvement in Patients with Myelofibrosis Treated with Nuvisertib (TP-3654), an Investigational Selective PIM1 Kinase Inhibitor

Blood (2024) 144 (Supplement 1): 3179.

https://doi.org/10.1182/blood-2024-200999

Published: 2024

Journal Articles

Nuvisertib (TP-3654), an Investigational Selective PIM1 Kinase Inhibitor, Showed Durable Clinical Response and Sustained Hematological Improvement in Relapsed/Refractory Myelofibrosis Patients

Blood (2024) 144 (Supplement 1): 655.

https://doi.org/10.1182/blood-2024-200312

Published: 2024

Journal Articles

Impact of a Functional NKG2D Genetic Variant on Lymphoma Susceptibility and NK Cell Immune Response to Epstein Barr Virus

Dong Thanh Le, Viet Hoang Nguyen, Giang Hoang Thao Nguyen, Akiyoshi Takami, Luis Espinoza

Blood (2024) 144 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2024-210034

Published: 2024

Journal Articles

Activation of mTOR Signal Bolster Natural Killer Cell Immunity Against EBV-Infected B Lymphocytes

Hoang Thao Giang Nguyen, Van Quan Nguyen, Dang Xuan Tran, Akiyoshi Takami, J. Luis Espinoza

Blood (2024) 144 (Supplement 1): 3917.

https://doi.org/10.1182/blood-2024-202773

Published: 2024

Journal Articles

Phase 1/2 Study of TP-3654, a Selective PIM1 Kinase Inhibitor: Preliminary Data Showed Clinical Activity and Cytokine Reductions in Relapsed/Refractory Myelofibrosis Patients

Blood (2023) 142 (Supplement 1): 626.

https://doi.org/10.1182/blood-2023-180164

Published: 2023

Journal Articles

Targeting Aberrantly Activated Glycolysis in Natural Killer T Cell Lymphomas

Luis Espinoza, Viet Hoang Nguyen, Ly Quoc Trung, Akiyoshi Takami

Blood (2023) 142 (Supplement 1): 5782.

https://doi.org/10.1182/blood-2023-188728

Published: 2023

Journal Articles

Eosinophils to Basophils Rate, Mean Platelet Volume, and Neutrophils to Lymphocyte Rate for the Diagnosis of Systemic Amyloidosis

Ly Quoc Trung, Viet Hoang Nguyen, Akiyoshi Takami, Luis Espinoza

Blood (2023) 142 (Supplement 1): 6747.

https://doi.org/10.1182/blood-2023-186797

Published: 2023

Journal Articles

Synergistic Effect of Venetoclax for Antibody Dependent Cell Cytotoxicity By Daratumumab

Ayano Nakamura, MD, Susumu Suzuki, PhD, Masao Seto, MD PhD, Souichi Takasugi, MD, Jo Kanasugi, MD, Ichiro Hanamura, MD PhD, Ryuzo Ueda, MD PhD, Akiyoshi Takami, MD PhD

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-134486

Published: 2020

Journal Articles

Allogeneic Stem Cell Transplantation in Patients with Philadelphia Chromosome-Positive Acute Myeloid Leukemia in Japan

Shohei Mizuno, MD PhD, Masamitsu Yanada, Koji Kawamura, Shingo Yano, MD PhD, Masayoshi Masuko, MD, Naoyuki Uchida, MD PhD, Yukiyasu Ozawa, MD PhD, Koji Iwato, Kazuteru Ohashi, MD PhD, Kazuhiro Ikegame, MD PhD, Sung-Won Kim, MD PhD, Masatsugu Tanaka, MD, Tetsuya Eto, MD PhD, Yoshinobu Kanda, MD PhD, Takahiro Fukuda, Yoshiko Atsuta, MD PhD, Akiyoshi Takami, MD

Blood (2019) 134 (Supplement_1): 2045.

https://doi.org/10.1182/blood-2019-122801

Published: 2019

Journal Articles

ABT-199 (venetoclax) Synergizes Cytotoxicity of Cytotoxic T-Cell (CTL) to B-Cell Lymphomas

Satsuki Murakami, MD, Susumu Suzuki, PhD, Ichiro Hanamura, MD PhD, Kazuhiro Yoshikawa, PhD, Ryuzo Ueda, MD PhD, Akiyoshi Takami, MD

Blood (2018) 132 (Supplement 1): 5154.

https://doi.org/10.1182/blood-2018-99-117471

Published: 2018

Journal Articles

Efficacy and Safety of Autologous Stem Cell Transplantation in Elderly Patients with Multiple Myeloma in the Era of Novel Agents

Shohei Mizuno, MD PhD, Koji Kawamura, MD PhD, Ichiro Hanamura, MD PhD, Kazutaka Sunami, MD PhD, Takehiko Mori, MD PhD, Fumihiko Nakamura, Shinsuke Iida, MD PhD, Hideyuki Nakazawa, PhD MD, Masanori Makita, Shinichi Kako, MD, Masashi Sawa, MD PhD, Yasunori Ueda, MD PhD, Hiroyuki Takahashi, MD PhD, Yoshinobu Kanda, MD PhD, Tatsuo Ichinohe, MD PhD, Yoshiko Atsuta, MD PhD, Hiroyuki Takamatsu, MD PhD, Akiyoshi Takami, MD

Blood (2018) 132 (Supplement 1): 3437.

https://doi.org/10.1182/blood-2018-99-109905

Published: 2018

Journal Articles

Establishment of a Novel DLBCL Cell Line: AMU-ML2, Derived from a Primary Refractory Patient Shows Homogeneous Staining Region of 8q24 Inducing High Expression of Long Non-Coding RNAs Encoded By PVT1 and Resistance to Vincristine

Shohei Mizuno, MD, PhD, Ichiro Hanamura, MD, PhD, Akinobu Ota, PhD, Sivasundaram Karnan, PhD, Kaori Uchino, MD, Tomohiro Horio, MD, Motonori Mizutani, MD PhD, Mineaki Goto, MD, PhD, Miyuki Takahashi, MD, PhD, Mayuko Gotou, MD, PhD, Yamamoto Hidesuke, MD, PhD, Masaya Watarai, MD, PhD, Masato Shikami, MD PhD, Yoshitaka Hosokawa, MD, PhD, Hiroshi Miwa, MD PhD, Ryuzo Ueda, MD PhD, Masakazu Nitta, MD PhD, Akiyoshi Takami, MD PhD

Blood (2016) 128 (22): 2950.

https://doi.org/10.1182/blood.V128.22.2950.2950

Published: 2016

Journal Articles

Analysis of the Prevalence and Risk Factors of Adult Neutropenia in a Large Cohort in Japan

Yasuhisa Yokoyama, MD,PhD, Masahiko Gosho, PhD, Takahiro Suzuki, MD, PhD, Akiyoshi Takami, MD, PhD, Yasushi Miyazaki, MD PhD, Koichi Akashi, MD PhD, Shigeru Chiba, MD, PhD

Blood (2016) 128 (22): 4738.

https://doi.org/10.1182/blood.V128.22.4738.4738

Published: 2016

Journal Articles

Efficacy of High-Dose Cytarabine Added to Cyclophosphamide/Total-Body Irradiation in the Conditioning Regimen of Allogeneic Hematopoietic Cell Transplantation for Myeloid Malignancy

Yasuyuki Arai, MD, Kazunari Aoki, MD, June Takeda, MD, Tadakazu Kondo, MD, Tetsuya Eto, MD PhD, Shuichi Ota, MD, Hisako Hashimoto, MD, Takahiro Fukuda, MD, Yukiyasu Ozawa, MD, Yoshinobu Kanda, MD PhD, Chiaki Kato, MD, Mineo Kurokawa, MD, Koji Iwato, MD, Makoto Onizuka, MD, Tatsuo Ichinohe, MD, Yoshiko Atsuta, MDPhD, Akiyoshi Takami, MD

Blood (2015) 126 (23): 734.

https://doi.org/10.1182/blood.V126.23.734.734

Published: 2015

Journal Articles

Outcome and Risk Factors for Therapy-Related Myeloid Neoplasms Treated with Allogeneic Stem Cell Transplantation

Michiko Kida, MDPhD, Kensuke Usuki, MDPhD, Naoyuki Uchida, MDPhD, Takahiro Fukuda, MD, Koji Iwato, MD, Ken-ichi Matsuoka, MDPhD, Tetsuya Eto, MD PhD, Tatsuo Ichinohe, MDPhD, Yoshiko Atsuta, MDPhD, Minoko Takanashi, MD PhD, Akiyoshi Takami, MD PhD, Yasushi Miyazaki, MD PhD, Shingo Yano, MDPhD, Ken Ishiyama, MD PhD

Blood (2015) 126 (23): 4371.

https://doi.org/10.1182/blood.V126.23.4371.4371

Published: 2015

Journal Articles

Efficiency of high-dose cytarabine added to CY/TBI in cord blood transplantation for myeloid malignancy

Yasuyuki Arai, June Takeda, Kazunari Aoki, Tadakazu Kondo, Satoshi Takahashi, Yasushi Onishi, Yukiyasu Ozawa, Nobuyuki Aotsuka, Yasuji Kouzai, Hirohisa Nakamae, Shuichi Ota, Chiaki Nakaseko, Hiroki Yamaguchi, Koji Kato, Yoshiko Atsuta, Akiyoshi Takami

Blood (2015) 126 (3): 415–422.

https://doi.org/10.1182/blood-2015-04-642652

Published: 2015

Includes: Supplemental data

Journal Articles

Comparable Leukemia-Free Survival after Autologous Hematopoietic Cell Transplantation Versus HLA-Identical Sibling Hematopoietic Cell Transplantation for Adult Acute Myeloid Leukemia in First Complete Remission: A Registry Study By the Adult AML Working Group of the Japan Society for Hematopoietic Cell Transplantation

Motonori Mizutani, MD, Masahiko Hara, Hiroyuki Fujita, Jun Aoki, Heiwa Kanamori, Shinichiro Machida, Satoshi Yamasaki, MD PhD, Kazuteru Ohashi, MD PhD, Kensuke Usuki, MDPhD, Takahiro Fukuda, MD, Takaaki Chou, Junji Tanaka, MD PhD, Yoshiko Atsuta, MDPhD, Akiyoshi Takami, MD PhD

Blood (2014) 124 (21): 2514.

https://doi.org/10.1182/blood.V124.21.2514.2514

Published: 2014

Journal Articles

The Effects of the Repeated Administration of Resveratrol Monomer and Resveratrol Dimer on Circulating Immune Cells in Healthy Individuals

Luis J. Espinoza, MD PhD, Ly Quoc Trung, MD PhD, Akiyo Yoshida, MD, Kayoko Yamada, BSC, Shinji Nakao, MD PhD, Akiyoshi Takami

Blood (2014) 124 (21): 4141.

https://doi.org/10.1182/blood.V124.21.4141.4141

Published: 2014

Journal Articles

Impact of Low-Dose TBI on Outcome of Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation from HLA Identical Sibling for Acute Myeloid Leukemia

Jun Aoki, MD, Sachiko Seo, MD, Masatsugu Tanaka, MD, Heiwa Kanamori, Takahiro Fukuda, MD, Naoki Kobayashi, MD PhD, Makoto Onizuka, MD, Tatsuo Ichinohe, MD PhD, Yoshiko Atsuta, MDPhD, Akiyoshi Takami

Blood (2014) 124 (21): 3893.

https://doi.org/10.1182/blood.V124.21.3893.3893

Published: 2014

Journal Articles

Amylase-Producing Myeloma Cells Reduced Sensitivity to Dexamethasone and Bortezomib.

Shohei Mizuno, MD, Ichiro Hanamura, MD PhD, Akinobu Ota, Karnan Sivasundaram, Tomoko Narita, MD, Masaki Ri, MD PhD, Motonori Mizutani, MD, Mineaki Goto, MD PhD, Mayuko Gotou, MD PhD, Norikazu Tsunekawa, MD PhD, Masato Shikami, MD PhD, Shinsuke Iida, Yoshitaka Hosokawa, MD PhD, Hiroshi Miwa, MD PhD, Ryuzo Ueda, MD PhD, Masakazu Nitta, MD PhD, Akiyoshi Takami, MD PhD

Blood (2014) 124 (21): 5690.

https://doi.org/10.1182/blood.V124.21.5690.5690

Published: 2014

NARROW

Cytokine Modulation Correlates Strongly with Symptom Improvement in Patients with Myelofibrosis Treated with Nuvisertib (TP-3654), an Investigational Selective PIM1 Kinase Inhibitor

Nuvisertib (TP-3654), an Investigational Selective PIM1 Kinase Inhibitor, Showed Durable Clinical Response and Sustained Hematological Improvement in Relapsed/Refractory Myelofibrosis Patients

Impact of a Functional NKG2D Genetic Variant on Lymphoma Susceptibility and NK Cell Immune Response to Epstein Barr Virus

Activation of mTOR Signal Bolster Natural Killer Cell Immunity Against EBV-Infected B Lymphocytes

Phase 1/2 Study of TP-3654, a Selective PIM1 Kinase Inhibitor: Preliminary Data Showed Clinical Activity and Cytokine Reductions in Relapsed/Refractory Myelofibrosis Patients

Targeting Aberrantly Activated Glycolysis in Natural Killer T Cell Lymphomas

Eosinophils to Basophils Rate, Mean Platelet Volume, and Neutrophils to Lymphocyte Rate for the Diagnosis of Systemic Amyloidosis

Synergistic Effect of Venetoclax for Antibody Dependent Cell Cytotoxicity By Daratumumab

Allogeneic Stem Cell Transplantation in Patients with Philadelphia Chromosome-Positive Acute Myeloid Leukemia in Japan

ABT-199 (venetoclax) Synergizes Cytotoxicity of Cytotoxic T-Cell (CTL) to B-Cell Lymphomas

Efficacy and Safety of Autologous Stem Cell Transplantation in Elderly Patients with Multiple Myeloma in the Era of Novel Agents

Establishment of a Novel DLBCL Cell Line: AMU-ML2, Derived from a Primary Refractory Patient Shows Homogeneous Staining Region of 8q24 Inducing High Expression of Long Non-Coding RNAs Encoded By PVT1 and Resistance to Vincristine

Analysis of the Prevalence and Risk Factors of Adult Neutropenia in a Large Cohort in Japan

Efficacy of High-Dose Cytarabine Added to Cyclophosphamide/Total-Body Irradiation in the Conditioning Regimen of Allogeneic Hematopoietic Cell Transplantation for Myeloid Malignancy

Outcome and Risk Factors for Therapy-Related Myeloid Neoplasms Treated with Allogeneic Stem Cell Transplantation

Efficiency of high-dose cytarabine added to CY/TBI in cord blood transplantation for myeloid malignancy

The Effects of the Repeated Administration of Resveratrol Monomer and Resveratrol Dimer on Circulating Immune Cells in Healthy Individuals

Impact of Low-Dose TBI on Outcome of Reduced Intensity Allogeneic Hematopoietic Stem Cell Transplantation from HLA Identical Sibling for Acute Myeloid Leukemia

Amylase-Producing Myeloma Cells Reduced Sensitivity to Dexamethasone and Bortezomib.

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American Society of Hematology

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American Society of Hematology

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