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Journal Articles

Activation of mTOR Signal Bolster Natural Killer Cell Immunity Against EBV-Infected B Lymphocytes

Hoang Thao Giang Nguyen, Van Quan Nguyen, Dang Xuan Tran, Akiyoshi Takami, J. Luis Espinoza

Blood (2024) 144 (Supplement 1): 3917.

https://doi.org/10.1182/blood-2024-202773

Published: 2024

Journal Articles

Impact of a Functional NKG2D Genetic Variant on Lymphoma Susceptibility and NK Cell Immune Response to Epstein Barr Virus

Dong Thanh Le, Viet Hoang Nguyen, Giang Hoang Thao Nguyen, Akiyoshi Takami, Luis Espinoza

Blood (2024) 144 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2024-210034

Published: 2024

Journal Articles

Targeting Aberrantly Activated Glycolysis in Natural Killer T Cell Lymphomas

Luis Espinoza, Viet Hoang Nguyen, Ly Quoc Trung, Akiyoshi Takami

Blood (2023) 142 (Supplement 1): 5782.

https://doi.org/10.1182/blood-2023-188728

Published: 2023

Journal Articles

Eosinophils to Basophils Rate, Mean Platelet Volume, and Neutrophils to Lymphocyte Rate for the Diagnosis of Systemic Amyloidosis

Ly Quoc Trung, Viet Hoang Nguyen, Akiyoshi Takami, Luis Espinoza

Blood (2023) 142 (Supplement 1): 6747.

https://doi.org/10.1182/blood-2023-186797

Published: 2023

Journal Articles

A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β

Tanabe Mikoto, MD, Nguyen Hoang Maianh, MD, Kohei Hosokawa, MD PhD, Noriharu Nakagawa, MD, Luis Espinoza, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 3736.

https://doi.org/10.1182/blood-2019-126677

Published: 2019

Journal Articles

Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Eiji Kobayashi, PhD, Yoshiki Akatsuka, MD PhD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Tanabe Mikoto, MD, Noriaki Tsuji, MD, Takeshi Yoroidaka, MD, Hiroki Mizumaki, MD, Thi Mai Anh Nguyen, MD, Takamasa Katagiri, PhD, Kiyomi Shitaoka, PhD, Hiroshi Hamana, PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 3751.

https://doi.org/10.1182/blood-2019-125685

Published: 2019

Journal Articles

The Depletion of TGF-β Co-Receptor CD109 Induces Erythroid Differentiation of TF-1 Cells: A Model of Preferential Commitment of PIGA -Mutated Hematopoietic Stem Cells in Immune-Mediated Bone Marrow Failure

Tanabe Mikoto, MD, Noriharu Nakagawa, MD, Kohei Hosokawa, MD PhD, Luis Espinoza, MD PhD, Kana Maruyama, Takamasa Katagiri, PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2018) 132 (Supplement 1): 3874.

https://doi.org/10.1182/blood-2018-99-118741

Published: 2018

Journal Articles

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Mahmoud Ibrahim Elbadry, MD, Hiroki Mizumaki, MD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Kazuhisa Chonabayashi, MD PhD, Yoshinori Yoshida, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD PhD, Tatsuya Imi, MD, Nguyen Thi Mai Anh, MD, Yoichi Fujii, MD, Seishi Ogawa, MD PhD, Katsuto Takenaka, MD PhD, Koichi Akashi, MD PhD, Shinji Nakao, MD PhD

Blood (2018) 132 (Supplement 1): 3855.

https://doi.org/10.1182/blood-2018-99-113756

Published: 2018

Journal Articles

Identification of a Patients-Derived CD34+ Myeloma Cell Population with Tumor-Propagating Capacity and Resistance to Anticancer Drugs

Kentaro Serizawa, Hirokazu Tanaka, MD PhD, Ayano Fukui, MD, Ryosuke Fujiwara, MD, Keigo Sano, MD, Hiroaki Inoue, MD, Takahiro Kumode, MD, Yasuhiro Taniguchi, MD, Yasuyoshi Morita, MD, Luis Espinoza, MDPhD, Itaru Matsumura, MDPhD

Blood (2017) 130 (Supplement 1): 1774.

https://doi.org/10.1182/blood.V130.Suppl_1.1774.1774

Published: 2017

Journal Articles

Imatinib Induces Apoptosis of NK/T Cell Neoplasms by Inhibiting Hematopoietic Cell Kinase and NQO2

Takeshi Yoroidaka, MD, Luis Espinoza, MDPhD, Kenichi Harada, MD PhD, Ly Quoc Trung, MD PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 1270.

https://doi.org/10.1182/blood.V130.Suppl_1.1270.1270

Published: 2017

Journal Articles

Relatively Low Sensitivity of CD109(-) Hematopoietic Stem/Progenitor Cells (HSPCs) to TGF-β: A Possible Mechanism Responsible for the Preferential Commitment of Piga Mutant HSPCs in Immune-Mediated Bone Marrow Failure

Noriharu Nakagawa, Kohei Hosokawa, Luis Espinoza, Kana Maruyama, Takamasa Katagiri, Hirohito Yamazaki, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 3911.

https://doi.org/10.1182/blood.V128.22.3911.3911

Published: 2016

Journal Articles

Treatment of Ex Vivo Expanded NK Cells with Daratumumab F(ab')2 Fragments Protects Adoptively Transferred NK Cells from Daratumumab-Mediated Killing and Augments Daratumumab-Induced Antibody Dependent Cellular Toxicity (ADCC) of Myeloma

Elena Cherkasova, PhD, Luis Espinoza, MD PhD, Ritesh Kotecha, Robert N. Reger, B.S., Maria Berg, Georg Aue, Ricardo M. Attar, PhD, A Kate Sasser, Mattias Carlsten, MD, PhD, Richard W. Childs, MD

Blood (2015) 126 (23): 4244.

https://doi.org/10.1182/blood.V126.23.4244.4244

Published: 2015

Journal Articles

Generation of Ips Cell-Derived Hematopoietic Progenitor Cells from Patients with Acquired Aplastic Anemia Harboring Copy Number Neutral Loss of Heterozygosity of the Short Arm of Chromosome 6

Luis Espinoza, MD PhD, Yoshinori Yoshida, MD PhD, Kazuhisa Chonabayashi, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 2415.

https://doi.org/10.1182/blood.V126.23.2415.2415

Published: 2015

Journal Articles

Improved Homing To Bone Marrow, Spleen and Lung Of Adoptively Infused NK Cells Expanded Ex Vivo With The Small Molecule Nicotinamide Using Feeder-Free Conditions

Gabi M. Frei, Maria Berg, Tony Peled, MSc, Robert N. Reger, Ritesh Kotecha, Toshihiro Onishi, MD, Luis Espinoza-Calderon, Nurit Persi, Chana Lador, Amnon Peled, Richard W. Childs, MD

Blood (2013) 122 (21): 897.

https://doi.org/10.1182/blood.V122.21.897.897

Published: 2013

Journal Articles

Association of Functional Single Nucleotide Variation in the NLRP3 Gene with Survival Outcomes After Unrelated Bone Marrow Transplantation.

Akiyoshi Takami, MD, PhD, FJSIM, J. Luis Espinoza, MD, PhD, Keitaro Matsuo, MD, PhD, Yasuo Morishima, MD, PhD, Makoto Onizuka, MD, PhD, Koichi Kashiwase, PhD, Takahiro Fukuda, MD, PhD, Yoshihisa Kodera, MD, PhD, Shinji Nakao, MD, PhD

Blood (2012) 120 (21): 3140.

https://doi.org/10.1182/blood.V120.21.3140.3140

Published: 2012

Journal Articles

Hematopoietic Stem Cell Differentiation Pathway in Humans Deduced From the Lineage Diversity of PNH-Type Cells in Patients with Bone Marrow Failure.

Takamasa Katagiri, Zhirong Qi, Yu Kiyu, MD, Naomi Sugimori, MD, PhD, J. Luis Espinoza, M.D., Akiyoshi Takami, MD, PhD, Shigeki Ohtake, MD, PhD, Shinji Nakao, MD, PhD

Blood (2009) 114 (22): 1489.

https://doi.org/10.1182/blood.V114.22.1489.1489

Published: 2009

Journal Articles

GPI-AP Deficient Cells Detected Exclusively in T Cells in Patients with Aplastic Anemia: Evidence against An Escape Mechanism for the Initial Proliferation of PIG-A Mutant Hematopoietic Stem Cells.

Takamasa Katagiri, Zhirong Qi, Yu Kiyu, MD, Naomi Sugimori, MD, PhD, J. Luis Espinoza, M.D., Akiyoshi Takami, MD, PhD, Shigeki Ohtake, MD, PhD, Shinji Nakao, MD, PhD

Blood (2009) 114 (22): 3197.

https://doi.org/10.1182/blood.V114.22.3197.3197

Published: 2009

Journal Articles

Identification of a Novel Auto-Antibody Highly Prevalent in Patients with Hepatitis-Associated and Idiopathic Aplastic Anemia.

Hiroyuki Takamatsu, MD, PhD, Zhirong Qi, Tomoyuki Sakurai, Luis Espinoza, M.D., Naomi Sugimori, MD, PhD, Hirohito Yamazaki, MD, PhD, Katsuya Okawa, Shinji Nakao, MD, PhD

Blood (2009) 114 (22): 3200.

https://doi.org/10.1182/blood.V114.22.3200.3200

Published: 2009

Journal Articles

GITR Ligation with GITR Ligand On Leukemic Cells Suppresses Induction of Leukemia-Associated Antigen Specific T Cells by Increasing Indoleamine 2, 3-Dioxygenase (IDO) Activity Leading to Kynurenine Secretion.

Yukio Kondo, MD, PhD, Luis Espinoza, MD, PhD, Takamasa Katagiri, PhD, Zhirong Qi, MD, Shinji Nakao, MD, PhD

Blood (2009) 114 (22): 3557.

https://doi.org/10.1182/blood.V114.22.3557.3557

Published: 2009

Journal Articles

Significant Impact of IL-17A Gene Polymorphism On Transplant Outcomes After HLA-Fully-Matched Unrelated Bone Marrow Transplantation.

Akiyoshi Takami, MD, PhD, J. Luis Espinoza, MD, Makoto Onizuka, MD, PhD, Takakazu Kawase, MD, PhD, Takamasa Katagiri, BSc, Shigeki Ohtake, MD, PhD, Yasuo Morishima, MD, PhD, Takahiro Fukuda, MD, PhD, Yoshihisa Kodera, MD, PhD, Shinji Nakao, MD, PhD

Blood (2009) 114 (22): 2305.

https://doi.org/10.1182/blood.V114.22.2305.2305

Published: 2009

NARROW

Activation of mTOR Signal Bolster Natural Killer Cell Immunity Against EBV-Infected B Lymphocytes

Impact of a Functional NKG2D Genetic Variant on Lymphoma Susceptibility and NK Cell Immune Response to Epstein Barr Virus

Targeting Aberrantly Activated Glycolysis in Natural Killer T Cell Lymphomas

Eosinophils to Basophils Rate, Mean Platelet Volume, and Neutrophils to Lymphocyte Rate for the Diagnosis of Systemic Amyloidosis

A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β

Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia

The Depletion of TGF-β Co-Receptor CD109 Induces Erythroid Differentiation of TF-1 Cells: A Model of Preferential Commitment of PIGA -Mutated Hematopoietic Stem Cells in Immune-Mediated Bone Marrow Failure

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Identification of a Patients-Derived CD34+ Myeloma Cell Population with Tumor-Propagating Capacity and Resistance to Anticancer Drugs

Imatinib Induces Apoptosis of NK/T Cell Neoplasms by Inhibiting Hematopoietic Cell Kinase and NQO2

Relatively Low Sensitivity of CD109(-) Hematopoietic Stem/Progenitor Cells (HSPCs) to TGF-β: A Possible Mechanism Responsible for the Preferential Commitment of Piga Mutant HSPCs in Immune-Mediated Bone Marrow Failure

Treatment of Ex Vivo Expanded NK Cells with Daratumumab F(ab')2 Fragments Protects Adoptively Transferred NK Cells from Daratumumab-Mediated Killing and Augments Daratumumab-Induced Antibody Dependent Cellular Toxicity (ADCC) of Myeloma

Generation of Ips Cell-Derived Hematopoietic Progenitor Cells from Patients with Acquired Aplastic Anemia Harboring Copy Number Neutral Loss of Heterozygosity of the Short Arm of Chromosome 6

Improved Homing To Bone Marrow, Spleen and Lung Of Adoptively Infused NK Cells Expanded Ex Vivo With The Small Molecule Nicotinamide Using Feeder-Free Conditions

Association of Functional Single Nucleotide Variation in the NLRP3 Gene with Survival Outcomes After Unrelated Bone Marrow Transplantation.

Hematopoietic Stem Cell Differentiation Pathway in Humans Deduced From the Lineage Diversity of PNH-Type Cells in Patients with Bone Marrow Failure.

GPI-AP Deficient Cells Detected Exclusively in T Cells in Patients with Aplastic Anemia: Evidence against An Escape Mechanism for the Initial Proliferation of PIG-A Mutant Hematopoietic Stem Cells.

Identification of a Novel Auto-Antibody Highly Prevalent in Patients with Hepatitis-Associated and Idiopathic Aplastic Anemia.

GITR Ligation with GITR Ligand On Leukemic Cells Suppresses Induction of Leukemia-Associated Antigen Specific T Cells by Increasing Indoleamine 2, 3-Dioxygenase (IDO) Activity Leading to Kynurenine Secretion.

Significant Impact of IL-17A Gene Polymorphism On Transplant Outcomes After HLA-Fully-Matched Unrelated Bone Marrow Transplantation.

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American Society of Hematology

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American Society of Hematology

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