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Journal Articles

HLA Class I Allele-Deficient Clones Regenerate in Immune Aplastic Anemia without Anti-Thymocyte Globulin

Yoshitaka Zaimoku, Kazuyoshi Hosomichi, Noriaki Tsuji, Mikoto Tanabe, Noriharu Nakagawa, Takeshi Yoroidaka, Hiroki Mizumaki, Tatsuya Imi, Hiroyuki Maruyama, Kohei Hosokawa, Hiroyuki Takamatsu, Hirohito Yamazaki, Kazuya Sakai, Ishikazu Mizuno, Toshihiro Miyamoto, Shinji Nakao

Blood (2024) 144 (Supplement 1): 1307.

https://doi.org/10.1182/blood-2024-208660

Published: 2024

Journal Articles

HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Takeshi Yoroidaka, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Kohei Hosokawa, Takamasa Katagiri, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao

Blood (2022) 140 (Supplement 1): 710–711.

https://doi.org/10.1182/blood-2022-165962

Published: 2022

Journal Articles

Outcomes of Transplant-Eligible Patients with Myelodysplastic Syndrome-Refractory Anemia with Excess Blasts Registered in a Prospective Observational Study: The JALSG-CS11-MDS-SCT

Blood (2021) 138 (Supplement 1): 2925.

https://doi.org/10.1182/blood-2021-147587

Published: 2021

Journal Articles

The Copy Number of Disease-Associated HLA Alleles Predicts the Response to Immunosuppressive Therapy in Acquired Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Tatsuya Imi, Kohei Hosokawa, Hiroyuki Maruyama, Takamasa Katagiri, Takeshi Yoroidaka, Noriharu Nakagawa, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Shinji Nakao

Blood (2021) 138 (Supplement 1): 604.

https://doi.org/10.1182/blood-2021-148240

Published: 2021

Journal Articles

A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β

Tanabe Mikoto, MD, Nguyen Hoang Maianh, MD, Kohei Hosokawa, MD PhD, Noriharu Nakagawa, MD, Luis Espinoza, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 3736.

https://doi.org/10.1182/blood-2019-126677

Published: 2019

Journal Articles

Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Eiji Kobayashi, PhD, Yoshiki Akatsuka, MD PhD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Tanabe Mikoto, MD, Noriaki Tsuji, MD, Takeshi Yoroidaka, MD, Hiroki Mizumaki, MD, Thi Mai Anh Nguyen, MD, Takamasa Katagiri, PhD, Kiyomi Shitaoka, PhD, Hiroshi Hamana, PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 3751.

https://doi.org/10.1182/blood-2019-125685

Published: 2019

Journal Articles

The Depletion of TGF-β Co-Receptor CD109 Induces Erythroid Differentiation of TF-1 Cells: A Model of Preferential Commitment of PIGA -Mutated Hematopoietic Stem Cells in Immune-Mediated Bone Marrow Failure

Tanabe Mikoto, MD, Noriharu Nakagawa, MD, Kohei Hosokawa, MD PhD, Luis Espinoza, MD PhD, Kana Maruyama, Takamasa Katagiri, PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2018) 132 (Supplement 1): 3874.

https://doi.org/10.1182/blood-2018-99-118741

Published: 2018

Journal Articles

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Mahmoud Ibrahim Elbadry, MD, Hiroki Mizumaki, MD, Luis Espinoza, MD PhD, Noriharu Nakagawa, MD, Kazuhisa Chonabayashi, MD PhD, Yoshinori Yoshida, MD PhD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD PhD, Tatsuya Imi, MD, Nguyen Thi Mai Anh, MD, Yoichi Fujii, MD, Seishi Ogawa, MD PhD, Katsuto Takenaka, MD PhD, Koichi Akashi, MD PhD, Shinji Nakao, MD PhD

Blood (2018) 132 (Supplement 1): 3855.

https://doi.org/10.1182/blood-2018-99-113756

Published: 2018

Journal Articles

PNH-Phenotype Cells and HLA Class I Allele-Lacking Leukocytes Shared By Family Members Who Developed Acquire Aplastic Anemia: Studies on Six Pairs of Patients in Different Families

Hiroki Mizumaki, MD, Hirohito Yamazaki, MD PhD, Kazuyoshi Hosomichi, PhD, Noriharu Nakagawa, MD, Takeshi Yoroidaka, MD, Tatsuya Imi, MD, Hiromi Iwasaki, MD PhD, Mika Kuroiwa, Ryosuke Ogawa, MDPhD, Atsushi Tajima, PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 1176.

https://doi.org/10.1182/blood.V130.Suppl_1.1176.1176

Published: 2017

Journal Articles

Identification of T Cell Receptors Specific to Antigens Presented By HLA-B5401 on IPS Cell-Derived Hematopoietic Stem Cells in a Patient with Acquired Aplastic Anemia Carrying B5401-Lacking Leukocytes

Noriharu Nakagawa, MD, Mahmoud Ibrahim Elbadry, MD, Yoshiki Akatsuka, MD, Hiroshi Hamana, Kiyomi Shitaoka, Yoshinori Yoshida, MD PhD, Kazuhisa Chonabayashi, MD PhD, Tatsuya Imi, MD, Yoshitaka Zaimoku, MD, Katsuto Takenaka, Hiroshi Fujiwara, MD PhD, Hiroyuki Kishi, PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 2458.

https://doi.org/10.1182/blood.V130.Suppl_1.2458.2458

Published: 2017

Journal Articles

A Moderate Increase in the WT1 mRNA Copy Number in Peripheral Blood of Patients with Long-Standing Acquired Aplastic Anemia without Apparent Signs of Myelodysplastic Syndrome

Ken Ishiyama, MD PhD, Takeshi Yoroidaka, MD, Noriharu Nakagawa, MD, Hiroki Mizumaki, MD, Tatsuya Imi, MD, Kohei Hosokawa, Hirohito Yamazaki, MD PhD, Seishi Ogawa, MD PhD, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 2462.

https://doi.org/10.1182/blood.V130.Suppl_1.2462.2462

Published: 2017

Journal Articles

Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia

Yoshitaka Zaimoku, Hiroyuki Takamatsu, Kazuyoshi Hosomichi, Tatsuhiko Ozawa, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Takamasa Katagiri, Hiroyuki Kishi, Atsushi Tajima, Atsushi Muraguchi, Koichi Kashiwase, Shinji Nakao

Blood (2017) 129 (21): 2908–2916.

https://doi.org/10.1182/blood-2016-11-752378

Published: 2017

Includes: Supplemental data

Journal Articles

HLA Class I Allele-Lacking Hematopoietic Stem/Progenitor Cells Support Long-Term Clonal Hematopoiesis without Oncogenic Driver Mutations in Acquired Aplastic Anemia

Tatsuya Imi, MD, Takamasa Katagiri, Kazuyoshi Hosomichi, PhD, Noriharu Nakagawa, Yoshitaka Zaimoku, MD, Ken Ishiyama, MD PhD, Atsushi Tajima, PhD, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 3894.

https://doi.org/10.1182/blood.V128.22.3894.3894

Published: 2016

Journal Articles

Relatively Low Sensitivity of CD109(-) Hematopoietic Stem/Progenitor Cells (HSPCs) to TGF-β: A Possible Mechanism Responsible for the Preferential Commitment of Piga Mutant HSPCs in Immune-Mediated Bone Marrow Failure

Noriharu Nakagawa, Kohei Hosokawa, Luis Espinoza, Kana Maruyama, Takamasa Katagiri, Hirohito Yamazaki, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 3911.

https://doi.org/10.1182/blood.V128.22.3911.3911

Published: 2016

Journal Articles

Identification of an HLA Class I Allele Closely Involved in the Pathogenesis of Acquired Aplastic Anemia

Yoshitaka Zaimoku, MD, Hiroyuki Takamatsu, MD PhD, Kazuyoshi Hosomichi, PhD, Tatsuhiko Ozawa, PhD, Noriharu Nakagawa, Tatsuya Imi, MD, Hiroyuki Kishi, PhD, Koichi Kashiwase, MD PhD, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 729.

https://doi.org/10.1182/blood.V128.22.729.729

Published: 2016

Journal Articles

Evidence That T Cells Specific for Non-Hematopoietic Cells Trigger the Development of Acquired Aplastic Anemia

Tatsuya Imi, Hiroyuki Maruyama, MD, Takamasa Katagiri, PhD, Yoshitaka Zaimoku, MD, Kana Maruyama, MD, Noriharu Nakagawa, MD, Kohei Hosokawa, MDPhD, Ken Ishiyama, Hirohito Yamazaki, MD PhD, Koichi Kashiwase, MD PhD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 1168.

https://doi.org/10.1182/blood.V126.23.1168.1168

Published: 2015

Journal Articles

Evidence for a Common Immune Pathophysiology in Acquired Aplastic Anemia and Ulcerative Colitis

Noriharu Nakagawa, MD, Hiroyuki Maruyama, MD, Yoshitaka Zaimoku, MD, Kana Maruyama, MD, Chizuru Saito, MD, Takamasa Katagiri, PhD, Kohei Hosokawa, MD PhD, Ken Ishiyama, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 2418.

https://doi.org/10.1182/blood.V126.23.2418.2418

Published: 2015

NARROW

HLA Class I Allele-Deficient Clones Regenerate in Immune Aplastic Anemia without Anti-Thymocyte Globulin

HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia

Outcomes of Transplant-Eligible Patients with Myelodysplastic Syndrome-Refractory Anemia with Excess Blasts Registered in a Prospective Observational Study: The JALSG-CS11-MDS-SCT

The Copy Number of Disease-Associated HLA Alleles Predicts the Response to Immunosuppressive Therapy in Acquired Aplastic Anemia

A GPI-Anchored Protein, CD109, Protects Hematopoietic Progenitor Cells from Erythroid Differentiation Induced By TGF-β

Identification of T-Cell Receptors Specific to Antigens Presented By HLA-B4002 and B5401 in Acquired Aplastic Anemia

The Depletion of TGF-β Co-Receptor CD109 Induces Erythroid Differentiation of TF-1 Cells: A Model of Preferential Commitment of PIGA -Mutated Hematopoietic Stem Cells in Immune-Mediated Bone Marrow Failure

Escape Hematopoiesis By HLA-B5401-Lacking Hematopoietic Stem Progenitor Cells in Male Patients with Acquired Aplastic Anemia

PNH-Phenotype Cells and HLA Class I Allele-Lacking Leukocytes Shared By Family Members Who Developed Acquire Aplastic Anemia: Studies on Six Pairs of Patients in Different Families

Identification of T Cell Receptors Specific to Antigens Presented By HLA-B5401 on IPS Cell-Derived Hematopoietic Stem Cells in a Patient with Acquired Aplastic Anemia Carrying B5401-Lacking Leukocytes

A Moderate Increase in the WT1 mRNA Copy Number in Peripheral Blood of Patients with Long-Standing Acquired Aplastic Anemia without Apparent Signs of Myelodysplastic Syndrome

Identification of an HLA class I allele closely involved in the autoantigen presentation in acquired aplastic anemia

HLA Class I Allele-Lacking Hematopoietic Stem/Progenitor Cells Support Long-Term Clonal Hematopoiesis without Oncogenic Driver Mutations in Acquired Aplastic Anemia

Relatively Low Sensitivity of CD109(-) Hematopoietic Stem/Progenitor Cells (HSPCs) to TGF-β: A Possible Mechanism Responsible for the Preferential Commitment of Piga Mutant HSPCs in Immune-Mediated Bone Marrow Failure

Identification of an HLA Class I Allele Closely Involved in the Pathogenesis of Acquired Aplastic Anemia

Evidence That T Cells Specific for Non-Hematopoietic Cells Trigger the Development of Acquired Aplastic Anemia

Evidence for a Common Immune Pathophysiology in Acquired Aplastic Anemia and Ulcerative Colitis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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