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Journal Articles

Efficacy and Safety of Cyclosporine Monotherapy for Patients with Non-Severe Aplastic Anemia Not Requiring Transfusions: Results from a Prospective Multicenter Phase II Study

Naoko Hosono, Ken Ishiyama, Hiroki Yamaguchi, Masahide Yamazaki, Hiroyuki Maruyama, Kensuke Usuki, Kazuki Tanimoto, Hiroyuki Sugiura, Noboru Asada, Seishi Ogawa, Yuzuru Kanakura, Itaru Matsumura, Koichi Akashi, Shinji Nakao

Blood (2024) 144 (Supplement 1): 1312.

https://doi.org/10.1182/blood-2024-198830

Published: 2024

Journal Articles

HLA Class I Allele-Deficient Clones Regenerate in Immune Aplastic Anemia without Anti-Thymocyte Globulin

Yoshitaka Zaimoku, Kazuyoshi Hosomichi, Noriaki Tsuji, Mikoto Tanabe, Noriharu Nakagawa, Takeshi Yoroidaka, Hiroki Mizumaki, Tatsuya Imi, Hiroyuki Maruyama, Kohei Hosokawa, Hiroyuki Takamatsu, Hirohito Yamazaki, Kazuya Sakai, Ishikazu Mizuno, Toshihiro Miyamoto, Shinji Nakao

Blood (2024) 144 (Supplement 1): 1307.

https://doi.org/10.1182/blood-2024-208660

Published: 2024

Journal Articles

Efficacy and Safety of Eltrombopag Added to Rabbit Anti-Human Thymocyte Globulin+Cyclosporine in Aplastic Anemia: Results from a Prospective Multicenter Phase II Study

Ken Ishiyama, Ritsuro Suzuki, Kinuko Mitani, Hiroyuki Maruyama, Yasushi Onishi, Kensuke Usuki, Hideo Koh, Katsuto Takenaka, Seishi Ogawa, Kana Matsumoto, Takuto Takahashi, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Fumiaki Kiyomi, Itaru Matsumura, Koichi Akashi, Shinji Nakao

Blood (2024) 144 (Supplement 1): 2689.

https://doi.org/10.1182/blood-2024-193818

Published: 2024

Journal Articles

Frequent Loss of HLA-B*40:02 from Leukocytes in Male Patients with Hepatitis-Associated Aplastic Anemia

Blood (2024) 144 (Supplement 1): 1311.

https://doi.org/10.1182/blood-2024-197892

Published: 2024

Journal Articles

Single-Cell Dissection Reveals a Distinct Origin of Small Paroxysmal Nocturnal Hemoglobinuria Clones in Immune Aplastic Anemia and Healthy Individuals

Dung Cao Cao Tran, Yoshitaka Zaimoku, Kazuyoshi Hosomichi, Hiroki Mizumaki, Kohei Hosokawa, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao

Blood (2023) 142 (Supplement 1): 1344.

https://doi.org/10.1182/blood-2023-190964

Published: 2023

Journal Articles

Clinical Significance of a Miniscule GPI(-) Granulocyte Population in Patients with Bone Marrow Failure

Dung Cao Tran, Kohei Hosokawa, Hiroki Mizumaki, Yoshitaka Zaimoku, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Toshihiro Miyamoto, Shinji Nakao

Blood (2022) 140 (Supplement 1): 11453–11454.

https://doi.org/10.1182/blood-2022-170970

Published: 2022

Journal Articles

HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Takeshi Yoroidaka, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Kohei Hosokawa, Takamasa Katagiri, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao

Blood (2022) 140 (Supplement 1): 710–711.

https://doi.org/10.1182/blood-2022-165962

Published: 2022

Journal Articles

Efficacy and Safety of Long-Term Romiplostim Use for Refractory Aplastic Anemia

Blood (2022) 140 (Supplement 1): 8634–8637.

https://doi.org/10.1182/blood-2022-162895

Published: 2022

Journal Articles

Minor GPI(-) Granulocyte Populations in Patients with Acquired Aplastic Anemia and Healthy Individuals Are Derived from a Few Piga -Mutated Hematopoietic Stem Progenitor Cells

Hiroki Mizumaki, Dung Cao Tran, Kohei Hosokawa, Kazuyoshi Hosomichi, Hiroyuki Takamatsu, Hirohito Yamazaki, Atsushi Tajima, Ken Ishiyama, Shinji Nakao

Blood (2021) 138 (Supplement 1): 2181.

https://doi.org/10.1182/blood-2021-150504

Published: 2021

Journal Articles

Prospective Comparison Study of Prognostic Value of MRD Detected By 8-Color MFC (EuroFlow-NGF) and NGS in Patients with Multiple Myeloma in ASCT Setting

Blood (2021) 138 (Supplement 1): 3946.

https://doi.org/10.1182/blood-2021-146441

Published: 2021

Journal Articles

Comparison of MRD Detection in Autografts in Multiple Myeloma between Novel High-Sensitivity Euroflow-NGF and NGS

Ryota Urushihara, Naoki Takezako, Takeshi Yoroidaka, Takeshi Yamashita, Shinji Nakao, Hiroyuki Takamatsu

Blood (2021) 138 (Supplement 1): 3950.

https://doi.org/10.1182/blood-2021-149041

Published: 2021

Journal Articles

The Copy Number of Disease-Associated HLA Alleles Predicts the Response to Immunosuppressive Therapy in Acquired Aplastic Anemia

Yoshitaka Zaimoku, Hiroki Mizumaki, Tatsuya Imi, Kohei Hosokawa, Hiroyuki Maruyama, Takamasa Katagiri, Takeshi Yoroidaka, Noriharu Nakagawa, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Shinji Nakao

Blood (2021) 138 (Supplement 1): 604.

https://doi.org/10.1182/blood-2021-148240

Published: 2021

Journal Articles

Clinical Significance of Small PNH-Type Cell Populations in Bone Marrow Failure Syndromes - an Interim Analysis of Japanese Multicentrer Prospective Study -

Yasutaka Ueda, Kohei Hosokawa, Ken Ishiyama, Hiroyuki Takamori, Yuji Yonemura, Naoshi Obara, Hideyoshi Noji, Kiyoshi Ando, Tsutomu Shichishima, Takayuki Ikezoe, Shigeru Chiba, Haruhiko Ninomiya, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao

Blood (2021) 138 (Supplement 1): 1122.

https://doi.org/10.1182/blood-2021-146353

Published: 2021

Journal Articles

HLA class I allele–lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia

Blood (2021) 137 (25): 3576–3580.

https://doi.org/10.1182/blood.2020010586

Published: 2021

Includes: Supplemental data

Journal Articles

Clonal Hematopoiesis By HLA Class I Allele-Lacking Hematopoietic Stem Cells and Concomitant Aberrant Stem Cells Is Rarely Associated with Clonal Evolution to Secondary Myelodysplastic Syndrome and Acute Myeloid Leukemia in Patients with Acquired Aplastic Anemia

Kohei Hosokawa, MD PhD, Hiroki Mizumaki, MD, Takeshi Yoroidaka, MD, Hiroyuki Maruyama, MDPhD, Tatsuya Imi, MD PhD, Noriaki Tsuji, MD, Ryota Urushihara, MD, Mikoto Tanabe, MD, Yoshitaka Zaimoku, MDPhD, Mai Anh Thi Nguyen, MD, Dung Cao Tran, MD, Ken Ishiyama, MD PhD, Hirohito Yamazaki, MD PhD, Takamasa Katagiri, PhD, Kazuyoshi Hosomichi, PhD, Atsushi Tajima, PhD, Fumihiro Azuma, Seishi Ogawa, MD PhD, Shinji Nakao, MD PhD

Blood (2020) 136 (Supplement 1): 1–2.

https://doi.org/10.1182/blood-2020-138636

Published: 2020

Journal Articles

Epigenetic Loss of the HLA-DR15 Expression on Hematopoietic Stem Progenitor Cells in Patients with Acquired Aplastic Anemia Characterized By Cyclosporine Dependency: A Novel Mechanism Underlying the Immune Escape of Hematopoietic Stem Progenitor Cells

Noriaki Tsuji, MD, Kohei Hosokawa, MD PhD, Ryota Urushihara, MD, Mikoto Tanabe, MD, Hiroyuki Takamatsu, MDPhD, Ken Ishiyama, MD PhD, Hirohito Yamazaki, MD PhD, Shinji Nakao, MD PhD

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-136893

Published: 2020

Journal Articles

Minimal Residual Disease in Autografts and Bone Marrow of Patients with Multiple Myeloma: 8-Color Multiparameter Flow Cytometry (EuroFlow-NGF) Vs . Next-Generation Sequencing

Hiroyuki Takamatsu, MDPhD, Naoki Takezako, MDPhD, Takeshi Yoroidaka, MD, Takeshi Yamashita, MD, Ryoichi Murata, MD, Atsuko Yamazaki, MD, Masahiro Takeuchi, MD PhD, Naoya Mimura, MD PhD, Chiaki Nakaseko, MD PhD, Emiko Sakaida, MDPhD, Masahiro Onoda, MD, Yoshikazu Utsu, MD PhD, Motoharu Fukazawa, MD, Kosei Matsue, MDPhD, Shinji Nakao, MD PhD

Blood (2020) 136 (Supplement 1): 22–23.

https://doi.org/10.1182/blood-2020-137014

Published: 2020

Journal Articles

Olfactomedin 4 Inhibits Erythroid Differentiation of Leukemic Cell Lines Induced By TGF-β: A Model of Preferential Commitment of Del(13q) Hematopoietic Stem Cells in Immune-Mediated Bone Marrow Failure

Kohei Thi Hosokawa, MD PhD, Kohei Hosokawa, MD PhD, Tanabe Mikoto, MD, Md Mohiuddin, Takeshi Yoroidaka, MD, Hiroki Mizumaki, MD, Tatsuya Imi, MD PhD, Masaya Ueno, PhD, Atsushi Hirao, MD PhD, Shinji Nakao, MD PhD

Blood (2019) 134 (Supplement_1): 5000.

https://doi.org/10.1182/blood-2019-127767

Published: 2019

Journal Articles

Minimal Residual Disease Assessment Using Euroflow-NGF in Patients with Multiple Myeloma Treated with a Combination of Carfilzomib, Lenalidomide, and Dexamethasone (KRD)

Takeshi Yoroidaka, MD, Hiroyuki Takamatsu, MD PhD, Takeshi Yamashita, MD, Ryoichi Murata, MD, Kyoko Yoshihara, MD PhD, Satoshi Yoshihara, MD PhD, Mikio Ueda, MD PhD, Shinji Nakao, MD PhD, Kosei Matsue, MD PhD

Blood (2019) 134 (Supplement_1): 3130.

https://doi.org/10.1182/blood-2019-126552

Published: 2019

Journal Articles

Comparison of Minimal Residual Disease Detection between the Manual and Automated Gating Strategies of Euroflow Next-Generation Flow in Patients with Multiple Myeloma

Hiroyuki Takamatsu, MD PhD, Takeshi Yoroidaka, MD, Takeshi Yamashita, MD, Ryoichi Murata, MD, Mikio Ueda, MD PhD, Shinji Nakao, MD PhD, Kosei Matsue, MD PhD

Blood (2019) 134 (Supplement_1): 3083.

https://doi.org/10.1182/blood-2019-122398

Published: 2019

NARROW

Efficacy and Safety of Cyclosporine Monotherapy for Patients with Non-Severe Aplastic Anemia Not Requiring Transfusions: Results from a Prospective Multicenter Phase II Study

HLA Class I Allele-Deficient Clones Regenerate in Immune Aplastic Anemia without Anti-Thymocyte Globulin

Efficacy and Safety of Eltrombopag Added to Rabbit Anti-Human Thymocyte Globulin+Cyclosporine in Aplastic Anemia: Results from a Prospective Multicenter Phase II Study

Frequent Loss of HLA-B*40:02 from Leukocytes in Male Patients with Hepatitis-Associated Aplastic Anemia

Single-Cell Dissection Reveals a Distinct Origin of Small Paroxysmal Nocturnal Hemoglobinuria Clones in Immune Aplastic Anemia and Healthy Individuals

Clinical Significance of a Miniscule GPI(-) Granulocyte Population in Patients with Bone Marrow Failure

HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia

Efficacy and Safety of Long-Term Romiplostim Use for Refractory Aplastic Anemia

Minor GPI(-) Granulocyte Populations in Patients with Acquired Aplastic Anemia and Healthy Individuals Are Derived from a Few Piga -Mutated Hematopoietic Stem Progenitor Cells

Prospective Comparison Study of Prognostic Value of MRD Detected By 8-Color MFC (EuroFlow-NGF) and NGS in Patients with Multiple Myeloma in ASCT Setting

Comparison of MRD Detection in Autografts in Multiple Myeloma between Novel High-Sensitivity Euroflow-NGF and NGS

The Copy Number of Disease-Associated HLA Alleles Predicts the Response to Immunosuppressive Therapy in Acquired Aplastic Anemia

Clinical Significance of Small PNH-Type Cell Populations in Bone Marrow Failure Syndromes - an Interim Analysis of Japanese Multicentrer Prospective Study -

HLA class I allele–lacking leukocytes predict rare clonal evolution to MDS/AML in patients with acquired aplastic anemia

Clonal Hematopoiesis By HLA Class I Allele-Lacking Hematopoietic Stem Cells and Concomitant Aberrant Stem Cells Is Rarely Associated with Clonal Evolution to Secondary Myelodysplastic Syndrome and Acute Myeloid Leukemia in Patients with Acquired Aplastic Anemia

Epigenetic Loss of the HLA-DR15 Expression on Hematopoietic Stem Progenitor Cells in Patients with Acquired Aplastic Anemia Characterized By Cyclosporine Dependency: A Novel Mechanism Underlying the Immune Escape of Hematopoietic Stem Progenitor Cells

Minimal Residual Disease in Autografts and Bone Marrow of Patients with Multiple Myeloma: 8-Color Multiparameter Flow Cytometry (EuroFlow-NGF) Vs . Next-Generation Sequencing

Olfactomedin 4 Inhibits Erythroid Differentiation of Leukemic Cell Lines Induced By TGF-β: A Model of Preferential Commitment of Del(13q) Hematopoietic Stem Cells in Immune-Mediated Bone Marrow Failure

Minimal Residual Disease Assessment Using Euroflow-NGF in Patients with Multiple Myeloma Treated with a Combination of Carfilzomib, Lenalidomide, and Dexamethasone (KRD)

Comparison of Minimal Residual Disease Detection between the Manual and Automated Gating Strategies of Euroflow Next-Generation Flow in Patients with Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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