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Journal Articles

Efficacy and Safety of Long-Term Romiplostim Use for Refractory Aplastic Anemia

Blood (2022) 140 (Supplement 1): 8634–8637.

https://doi.org/10.1182/blood-2022-162895

Published: 2022

Journal Articles

Clinical Significance of Small PNH-Type Cell Populations in Bone Marrow Failure Syndromes - an Interim Analysis of Japanese Multicentrer Prospective Study -

Yasutaka Ueda, Kohei Hosokawa, Ken Ishiyama, Hiroyuki Takamori, Yuji Yonemura, Naoshi Obara, Hideyoshi Noji, Kiyoshi Ando, Tsutomu Shichishima, Takayuki Ikezoe, Shigeru Chiba, Haruhiko Ninomiya, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao

Blood (2021) 138 (Supplement 1): 1122.

https://doi.org/10.1182/blood-2021-146353

Published: 2021

Journal Articles

Transfusion Requirements in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria with or without a History of Bone Marrow Disorder Receiving Ravulizumab and Eculizumab: Results from a Phase 3 Non-Inferiority Study Extension

Antonio Risitano, Jun-Ho Jang, MD, Lee Gyeong-Won, Wanchai Wanachiwanawin, Hubert Schrezenmeier, Yuji Yonemura, MDPhD, Talha Munir, MBBS, Rodrigo Pavani, Jimmy Wang, Alexander D. Kulagin, MD PhD, Austin Kulasekararaj, MDMBBS,MRCP,FRCPath, Flore Sicre de Fontbrune, Alexander Röth, MD

Blood (2020) 136 (Supplement 1): 31–33.

https://doi.org/10.1182/blood-2020-140418

Published: 2020

Journal Articles

Overall Survival in Acquired Pure Red Cell Aplasia in Adults Following Immunosuppressive Therapy: Preliminary Results from the Nationwide Cohort Study (PRCA2016)

Naohito Fujishima, MD, Makoto Hirokawa, MD PhD, Kenichi Sawada, MD, Shinji Nakao, MD PhD, Yuji Yonemura, MD PhD, Akira Matsuda, MD, Norio Komatsu, MD PhD, Hideo Harigae, MD, Akiko Saito, MD, Kaoru Tohyama, MD, Itaru Matsumura, MD, Mineo Kurokawa, MD PhD, Shunya Arai, MD PhD, Kinuko Mitani, MD

Blood (2018) 132 (Supplement 1): 2593.

https://doi.org/10.1182/blood-2018-99-114245

Published: 2018

Journal Articles

Efficacy and Safety of Romiplostim in Patients with Acquired Aplastic Anemia Ineligible or Refractory to Immunosuppressive Therapy: Interim Analysis of Phase 2/3 Clinical Trial

Blood (2018) 132 (Supplement 1): 1306.

https://doi.org/10.1182/blood-2018-99-112478

Published: 2018

Journal Articles

Baseline Assessment of Patients with Newly-Diagnosed Acquired Bone Marrow Failure Enrolled in a Prospective Observational Study, "Search for Unidentified Links between PNH Clone Size and the Related Clinical Manifestations By High Precision Flow Cytometry (SUPREMACY)"

Yuji Yonemura, MD PhD, Tatsuya Kawaguchi, MD PhD, Ken Ishiyama, MD PhD, Chiharu Sugimori, MD PhD, Kohei Hosokawa, Naoshi Obara, MD PhD, Hideyoshi Noji, MD PhD, Yukari Shirasugi, MD PhD, Yasutaka Ueda, MD PhD, Hiroyuki Takamori, MD PhD, Tsutomu Shichishima, MD PhD, Shigeru Chiba, MD PhD, Haruhiko Ninomiya, MD PhD, Kiyoshi Ando, MD PhD, Jun-Ichi Nishimura, MD PhD, Yuzuru Kanakura, MD PhD, Masanori Takahashi, Shinji Nakao, MD PhD

Blood (2017) 130 (Supplement 1): 2466.

https://doi.org/10.1182/blood.V130.Suppl_1.2466.2466

Published: 2017

Journal Articles

Effects of Eculizumab Treatment on the Quality of Life in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated in Japan

Yasutaka Ueda, MD PhD, Naoshi Obara, MD PhD, Yuji Yonemura, MD PhD, Hideyoshi Noji, MD PhD, Takahisa Matsuda, Hirozumi Akiyama, Takayuki Ikezoe, MD, PhD, Shigeru Chiba, MD PhD, Yoshinobu Kanda, MD PhD, Tatsuya Kawaguchi, MD PhD, Tsutomu Shichishima, MD PhD, Hideki Nakakuma, MD PhD, Shinichiro Okamoto, MD PhD, Jun-Ichi Nishimura, MD PhD, Yuzuru Kanakura, MD PhD, Haruhiko Ninomiya, MD PhD

Blood (2017) 130 (Supplement 1): 4749.

https://doi.org/10.1182/blood.V130.Suppl_1.4749.4749

Published: 2017

Journal Articles

Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA2016

Blood (2017) 130 (Supplement 1): 4954.

https://doi.org/10.1182/blood.V130.Suppl_1.4954.4954

Published: 2017

Journal Articles

The First Follow-up Data Analysis of Patients with Acquired Bone Marrow Failure Harboring a Small Population of PNH-Type Cells in the Japanese, Multicenter, Prospective Study Optima

Yasutaka Ueda, MD PhD, Jun-Ichi Nishimura, MD PhD, Chiharu Sugimori, MD PhD, Kohei Hosokawa, MDPhD, Yuji Yonemura, MD PhD, Naoshi Obara, MDPhD, Hideyoshi Noji, MD PhD, Yoshihiko Nakamura, PhD, Yukari Shirasugi, MD PhD, Kiyoshi Ando, Tsutomu Shichishima, MD PhD, Haruhiko Ninomiya, MD PhD, Shigeru Chiba, MD, PhD, Tatsuya Kawaguchi, MD PhD, Yuzuru Kanakura, MD PhD, Shinji Nakao, MD PhD

Blood (2016) 128 (22): 3896.

https://doi.org/10.1182/blood.V128.22.3896.3896

Published: 2016

Journal Articles

An Interim 4-Year Analysis of Prospective Multicenter Observational Study of PNH-Type Cells in Japanese Patients with Bone Marrow Failure Syndrome (OPTIMA study)

Yukari Shirasugi, MD PhD, Hideyoshi Noji, MD PhD, Tsutomu Shichishima, MD PhD, Chiharu Sugimori, MD PhD, Naoshi Obara, MDPhD, Shigeru Chiba, MD, PhD, Haruhiko Ninomiya, MD PhD, Yoshihiko Nakamura, PhD, Kiyoshi Ando, MD PhD, Yuji Yonemura, MD PhD, Tatsuya Kawaguchi, MD PhD, Kohei Hosokawa, MDPhD, Yasutaka Ueda, MDPhD, Jun-Ichi Nishimura, MD PhD, Yuzuru Kanakura, MD PhD, Shinji Nakao, MD PhD

Blood (2015) 126 (23): 4781.

https://doi.org/10.1182/blood.V126.23.4781.4781

Published: 2015

Journal Articles

The Interim Analysis of the Optima (observation of GPI-anchored protein-deficient [PNH-type]) Cells in Japanese Patients with Bone Marrow Failure Syndrome and in Those Suspected of Having PNH) Study

Hideyoshi Noji, MD PhD, Tsutomu Shichishima, MD PhD, Chiharu Sugimori, MD PhD, Naoshi Obara, MD PhD, Kohei Hosokawa, MDPhD, Shigeru Chiba, MD PhD, Yoshihiko Nakamura, MD PhD, Kiyoshi Ando, MD PhD, Satoru Hayashi, MD PhD, Yuji Yonemura, MD PhD, Tatsuya Kawaguchi, MD PhD, Haruhiko Ninomiya, MD PhD, Jun-ichi Nishimura, MD PhD, Yuzuru Kanakura, MD PhD, Shinji Nakao, MD PhD

Blood (2014) 124 (21): 1595.

https://doi.org/10.1182/blood.V124.21.1595.1595

Published: 2014

Journal Articles

Baseline Assessment Of GPI-Anchored Protein Deficient Blood Cells In Patients With Bone Marrow Failure (The OPTIMA study)

Naoshi Obara, MD, PhD, Shigeru Chiba, MD, PhD, Kohei Hosokawa, MD, PhD, Chiharu Sugimori, MD, PhD, Masaki Yamamoto, MD, Hideyoshi Noji, MD, PhD, Yuji Yonemura, MD, PhD, Yoshihiko Nakamura, MD, PhD, Kiyoshi Ando, MD, PhD, Tatsuya Kawaguchi, MD, PhD, Tsutomu Shichishima, MD, PhD, Haruhiko Ninomiya, MD, PhD, Jun-ichi Nishimura, MD, PhD, Yuzuru Kanakura, Shinji Nakao, MD, PhD

Blood (2013) 122 (21): 1241.

https://doi.org/10.1182/blood.V122.21.1241.1241

Published: 2013

Journal Articles

Persistently high quality of life conferred by coexisting congenital deficiency of terminal complement C9 in a paroxysmal nocturnal hemoglobinuria patient

Nobuyoshi Hanaoka, Yoshiko Murakami, Masahide Nagata, Shoichi Nagakura, Yuji Yonemura, Takashi Sonoki, Taroh Kinoshita, Hideki Nakakuma

Blood (2012) 119 (16): 3866–3868.

https://doi.org/10.1182/blood-2012-02-408161

Published: 2012

Journal Articles

Evaluation of Romiplostim In a Randomized Placebo-Controlled Phase 3 Study of a Japanese Population with Chronic Immune Thrombocytopenia (ITP).

Koji Miyazaki, MD, Yukari Shirasugi, MD, Kiyoshi Ando, MD, PhD, Yoshiaki Tomiyama, MD, Shinichiro Okamoto, MD, PhD, Mineo Kurokawa, MD, Keita Kirito, MD, Yuji Yonemura, MD, PhD, Shinichiro Mori, MD, Kensuke Usuki, MD, PhD, Koji Iwato, MD, PhD, Satoshi Hashino, MD, PhD, Helen Wei, PhD, Richard Lizambri, MD

Blood (2010) 116 (21): 3704.

https://doi.org/10.1182/blood.V116.21.3704.3704

Published: 2010

Journal Articles

Isolation of Mesenchymal Stem Cells from Human Bone Marrow Using Aldehyde Dehydrogenase as a Marker.

Eishi Nishimoto, MD, Yasuhiro Yamada, M.D., Ph.D., Hirosada Miyake, M.D., Hiroaki Mitsuya, M.D., Ph.D., Yuji Yonemura, M.D., Ph.D.

Blood (2007) 110 (11): 1929.

https://doi.org/10.1182/blood.V110.11.1929.1929

Published: 2007

Journal Articles

NKG2D-Mediated Marrow Injury in Paroxysmal Nocturnal Hemoglobinuria and Its Related Disorders.

Nobuyoshi Hanaoka, MD, PhD, Tatsuya Kawaguchi, MD, PhD, Kentaro Horikawa, MD, PhD, Shoichi Nagakura, MD, PhD, Sonoko Ishihara, MD, PhD, Yasuchika Tsuzuki, MD, Yuji Yonemura, MD, PhD, Hideki Nakakuma, MD, PhD

Blood (2007) 110 (11): 3674.

https://doi.org/10.1182/blood.V110.11.3674.3674

Published: 2007

Journal Articles

Treatment of severe aplastic anemia with antithymocyte globulin and cyclosporin A with or without G-CSF in adults: a multicenter randomized study in Japan

Masanao Teramura, Akiro Kimura, Satsuki Iwase, Yuji Yonemura, Shinji Nakao, Akio Urabe, Mitsuhiro Omine, Hideaki Mizoguchi

Blood (2007) 110 (6): 1756–1761.

https://doi.org/10.1182/blood-2006-11-050526

Published: 2007

Includes: Supplemental data

Journal Articles

ULBP and MICA/B as Novel Indicators for Both Diagnosis of Immune-Mediated Marrow Injury and Favorable Response to Immunosuppressive Therapy in Bone Marrow Failure Syndromes.

Nobuyoshi Hanaoka, MD, PhD, Tatsuya Kawaguchi, MD, PhD, Kentaro Horikawa, MD, PhD, Shoichi Nagakura, MD, PhD, Yasuchika Tsuzuki, MD, Yuji Yonemura, MD, PhD, Hideki Nakakuma, MD, PhD

Blood (2006) 108 (11): 990.

https://doi.org/10.1182/blood.V108.11.990.990

Published: 2006

Journal Articles

Identification of Hepatic Progenitors Having No Hematopoietic Potential in Murine Bone Marrow.

Yasuhiro Yamada, MD, PhD, Hirosada Miyake, MD, Eishi Nishimoto, MD, Hiroaki Mitsuya, MD, PhD, Yuji Yonemura, MD, PhD

Blood (2006) 108 (11): 1684.

https://doi.org/10.1182/blood.V108.11.1684.1684

Published: 2006

Journal Articles

Hepatogenic Potential of Stem Cells and Lymphoid Precursors.

Yasuhiro Yamada, MD, Hirosada Miyake, MD, Eishi Nishimoto, MD, Hiroaki Mitsuya, MD, PhD, Yuji Yonemura, MD, PhD

Blood (2005) 106 (11): 1696.

https://doi.org/10.1182/blood.V106.11.1696.1696

Published: 2005

NARROW

Efficacy and Safety of Long-Term Romiplostim Use for Refractory Aplastic Anemia

Clinical Significance of Small PNH-Type Cell Populations in Bone Marrow Failure Syndromes - an Interim Analysis of Japanese Multicentrer Prospective Study -

Transfusion Requirements in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria with or without a History of Bone Marrow Disorder Receiving Ravulizumab and Eculizumab: Results from a Phase 3 Non-Inferiority Study Extension

Overall Survival in Acquired Pure Red Cell Aplasia in Adults Following Immunosuppressive Therapy: Preliminary Results from the Nationwide Cohort Study (PRCA2016)

Efficacy and Safety of Romiplostim in Patients with Acquired Aplastic Anemia Ineligible or Refractory to Immunosuppressive Therapy: Interim Analysis of Phase 2/3 Clinical Trial

Baseline Assessment of Patients with Newly-Diagnosed Acquired Bone Marrow Failure Enrolled in a Prospective Observational Study, "Search for Unidentified Links between PNH Clone Size and the Related Clinical Manifestations By High Precision Flow Cytometry (SUPREMACY)"

Effects of Eculizumab Treatment on the Quality of Life in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated in Japan

Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA2016

The First Follow-up Data Analysis of Patients with Acquired Bone Marrow Failure Harboring a Small Population of PNH-Type Cells in the Japanese, Multicenter, Prospective Study Optima

An Interim 4-Year Analysis of Prospective Multicenter Observational Study of PNH-Type Cells in Japanese Patients with Bone Marrow Failure Syndrome (OPTIMA study)

The Interim Analysis of the Optima (observation of GPI-anchored protein-deficient [PNH-type]) Cells in Japanese Patients with Bone Marrow Failure Syndrome and in Those Suspected of Having PNH) Study

Baseline Assessment Of GPI-Anchored Protein Deficient Blood Cells In Patients With Bone Marrow Failure (The OPTIMA study)

Persistently high quality of life conferred by coexisting congenital deficiency of terminal complement C9 in a paroxysmal nocturnal hemoglobinuria patient

Evaluation of Romiplostim In a Randomized Placebo-Controlled Phase 3 Study of a Japanese Population with Chronic Immune Thrombocytopenia (ITP).

Isolation of Mesenchymal Stem Cells from Human Bone Marrow Using Aldehyde Dehydrogenase as a Marker.

NKG2D-Mediated Marrow Injury in Paroxysmal Nocturnal Hemoglobinuria and Its Related Disorders.

Treatment of severe aplastic anemia with antithymocyte globulin and cyclosporin A with or without G-CSF in adults: a multicenter randomized study in Japan

ULBP and MICA/B as Novel Indicators for Both Diagnosis of Immune-Mediated Marrow Injury and Favorable Response to Immunosuppressive Therapy in Bone Marrow Failure Syndromes.

Identification of Hepatic Progenitors Having No Hematopoietic Potential in Murine Bone Marrow.

Hepatogenic Potential of Stem Cells and Lymphoid Precursors.

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American Society of Hematology

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American Society of Hematology

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