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Raajit Rampal
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Journal Articles

Proposals for revised International Working Group–European LeukemiaNet criteria for anemia response in myelofibrosis

Brief Report
Ayalew Tefferi, Giovanni Barosi, Francesco Passamonti, Juan-Carlos Hernandez-Boluda, Prithviraj Bose, Konstanze Döhner, Martin Ellis, Naseema Gangat, Jacqueline S. Garcia, Heinz Gisslinger, Jason Gotlib, Paola Guglielmelli, Vikas Gupta, Claire Harrison, Elizabeth O. Hexner, Gabriela S. Hobbs, Jean-Jacques Kiladjian, Steffen Koschmieder, Nicolaus Kroger, Andrew T. Kuykendall, Giuseppe G. Loscocco, John Mascarenhas, Lucia Masarova, Ruben Mesa, Barbara Mora, Olatoyosi Odenike, Stephen T. Oh, Animesh Pardanani, Anand Patel, Naveen Pemmaraju, Alessandro Rambaldi, Raajit Rampal, Shireen Sirhan, Natasha Szuber, Moshe Talpaz, Pankit J. Vachhani, Alessandro M. Vannucchi, Tiziano Barbui
Journal: Blood
Blood (2024) 144 (17): 1813–1820.
https://doi.org/10.1182/blood.2024025802
Published: 2024
Journal Articles

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

Andrew J. Dunbar, Dongjoo Kim, Min Lu, Mirko Farina, Robert L. Bowman, Julie L. Yang, Young Park, Abdul Karzai, Wenbin Xiao, Zach Zaroogian, Kavi O’Connor, Shoron Mowla, Francesca Gobbo, Paola Verachi, Fabrizio Martelli, Giuseppe Sarli, Lijuan Xia, Nada Elmansy, Maria Kleppe, Zhuo Chen, Yang Xiao, Erin McGovern, Jenna Snyder, Aishwarya Krishnan, Corrine Hill, Keith Cordner, Anouar Zouak, Mohamed E. Salama, Jayden Yohai, Eric Tucker, Jonathan Chen, Jing Zhou, Timothy McConnell, Anna R. Migliaccio, Richard Koche, Raajit Rampal, Rong Fan, Ross L. Levine, Ronald Hoffman
Journal: Blood
Blood (2023) 141 (20): 2508–2519.
https://doi.org/10.1182/blood.2022015418
Published: 2023
Includes: Supplemental data
Journal Articles

Prospective Analysis to Determine Barriers to Allogeneic Hematopoietic Cell Transplantation in Patients with Newly Diagnosed and Relapsed Acute Leukemia

Karthik Nath, Jasme Lee, Theresa A Elko, Lauren Levy, Elaina Preston, Sean M. Devlin, Doris M Ponce, Richard J. Lin, Brian C. Shaffer, Christina Cho, Ioannis Politikos, Ann A Jakubowski, Jae H Park, Raajit Rampal, Miguel-Angel Perales, Martin S. Tallman, Juliet N. Barker, Sergio A Giralt, Ellin Berman, Roni Tamari, Eytan Stein, Boglarka Gyurkocza
Journal: Blood
Blood (2022) 140 (Supplement 1): 2137–2139.
https://doi.org/10.1182/blood-2022-157193
Published: 2022
Journal Articles

The High Mobility Group A1 Chromatin Regulator Drives Immune Evasion during MPN Progression By Repressing Genes Involved in Antigen Presentation and Immune Attack

Joseph Kim, Jung-Hyun Kim, Leslie Cope, Liping Li, Raajit Rampal, Richard Koche, Donna M Williams, Jerry L. Spivak, Alison R. Moliterno, Linda Resar
Journal: Blood
Blood (2021) 138 (Supplement 1): 2546.
https://doi.org/10.1182/blood-2021-151139
Published: 2021
Journal Articles

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) As Demonstrated By Improvements in Bone Marrow Function and Clinical Activity in Patients with Myelofibrosis - Preliminary Data

Srdan Verstovsek, Mohamed E Salama, John Mascarenhas, Moshe Talpaz, Ruben A. Mesa, Alessandro Vannucchi, Raajit Rampal, Stephen T. Oh, Horatiu Olteanu, April Chiu, Dong Chen, Curtis A. Hanson, Natalia Curto-Garcia, Pietro Taverna, Jike Cui, Oksana Zavidij, Zehua Chen, Gozde Colak, Sergey Efuni, Patricia J Keller, Patrick Trojer, Claire N. Harrison
Journal: Blood
Blood (2021) 138 (Supplement 1): 2568.
https://doi.org/10.1182/blood-2021-152267
Published: 2021
Journal Articles

The Impact of Pacritinib on Myelofibrosis Symptoms in Patients with Moderate and Severe Thrombocytopenia: A Retrospective Analysis of Patients in the Persist-2 Study

Jeanne M. Palmer, Ruben A. Mesa, Stephen T. Oh, Raajit Rampal, Sarah A Buckley, Karisse Roman-Torres, Srdan Verstovsek, John Mascarenhas, Alessandro M. Vannucchi, Jean-Jacques Kiladjian, Claire N. Harrison, Prithviraj Bose, Adam R Craig, Aaron T. Gerds
Journal: Blood
Blood (2021) 138 (Supplement 1): 3628.
https://doi.org/10.1182/blood-2021-144505
Published: 2021
Journal Articles

Safety Analysis of Pacritinib in Patients with Myelofibrosis and Severe Thrombocytopenia

John Mascarenhas, Claire N. Harrison, Aaron T. Gerds, Josef T. Prchal, Raajit Rampal, Sarah A Buckley, Adam R Craig, Jennifer A. Smith, John Volpone, Karisse Roman-Torres, Ruben A. Mesa
Journal: Blood
Blood (2021) 138 (Supplement 1): 3640.
https://doi.org/10.1182/blood-2021-151395
Published: 2021
Journal Articles

Subgroup Analysis from a Phase 2 Study of the Efficacy and Safety of Parsaclisib, a Selective PI3Kδ Inhibitor, in Combination with Ruxolitinib in Patients with Myelofibrosis (MF)

Abdulraheem Yacoub, Uma Borate, Raajit Rampal, Haris Ali, Eunice S. Wang, Aaron T. Gerds, Gabriela Hobbs, Marina Kremyanskaya, Elliott Winton, Casey O'Connell, Swati Goel, Stephen Oh, Gary J. Schiller, Albert Assad, Sue Erickson-Viitanen, Feng Zhou, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 3647.
https://doi.org/10.1182/blood-2021-148668
Published: 2021
Journal Articles

HMGA1 Chromatin Regulators Drive Progression in Myeloproliferative Neoplasms through Epigenetic Rewiring to Induce Networks Involved in GATA2 and Proliferation

Liping Li, Jung-Hyun Kim, Wenyan Lu, Leslie Cope, Donna M Williams, Joseph Kim, Raajit Rampal, Richard Koche, Lingling Xian, Li Luo, Marija Vasiljevic, Daniel R Matson, Zhizhuang Joe Zhao, Ophelia Rogers, Matthew C. Stubbs, Karen Reddy, Jerry L. Spivak, Alison R. Moliterno, Linda Resar
Journal: Blood
Blood (2021) 138 (Supplement 1): 625.
https://doi.org/10.1182/blood-2021-144712
Published: 2021
Journal Articles

The BMP/SMAD Pathway Is a Key Mediator of Leukemic Transformation of TP53-Mutant Post-MPN AML

Bing Li, Wenbin An, Hua Wang, Aishwarya Krishnan, Shoron Mowla, Timour Baslan, Richard Koche, Wenbin Xiao, Scott Lowe, Ross L. Levine, Raajit Rampal
Journal: Blood
Blood (2021) 138 (Supplement 1): 626.
https://doi.org/10.1182/blood-2021-152036
Published: 2021
Journal Articles

Safety and Efficacy of Cusatuzumab in Combination with Venetoclax and Azacitidine (CVA) in Patients with Previously Untreated Acute Myeloid Leukemia (AML) Who Are Not Eligible for Intensive Chemotherapy; An Open-Label, Multicenter, Phase 1b Study

Gail J. Roboz, Thomas Pabst, Ahmed Aribi, Joseph M. Brandwein, Hartmut Döhner, Walter Fiedler, Domenica Gandini, Michelle Geddes, Jing-Zhou Hou, Angela J. Howes, Anna Hultberg, Eric Huselton, Julie Jacobs, Colleen Kane, Ewa Lech-Marańda, Marieke Louwers, Kerri Nottage, Uwe Platzbecker, Raajit Rampal, Mariya Salman, Priya Shah, Don Stevens, Monic Stuart, Marion Subklewe, Anne Sumbul, Eunice S. Wang, Agnieszka Wierzbowska, Bin Yao, Karen Yee, Hagop Kantarjian, Gautam Borthakur
Journal: Blood
Blood (2021) 138 (Supplement 1): 369.
https://doi.org/10.1182/blood-2021-150371
Published: 2021
Journal Articles

Treatment of Myelofibrosis Patients with the TGF-β 1/3 Inhibitor AVID200 (MPN-RC 118) Induces a Profound Effect on Platelet Production

John Mascarenhas, Heidi E. Kosiorek, Rupali Bhave, Jeanne M. Palmer, Andrew T. Kuykendall, Ruben A. Mesa, Raajit Rampal, Aaron T. Gerds, Abdulraheem Yacoub, Kristen M. Pettit, Moshe Talpaz, Rami S. Komrokji, Marina Kremyanskaya, Agapito Gonzalez, Frank Fabris, Lonette Sandy, Kathryn Johnson, Mikaela Doughtery, Erin McGovern, Juan Arango Ossa, Dylan Domenico, Noushin Farnoud, Anna Rita Migliaccio, Mohamed E Salama, Rona Singer Weinberg, Amy Kong, Vesna Najfeld, Carolyn Mead-Harvey, Amylou C. Dueck, Lilian Varricchio, Ronald Hoffman
Journal: Blood
Blood (2021) 138 (Supplement 1): 142.
https://doi.org/10.1182/blood-2021-148995
Published: 2021
Journal Articles

Pelabresib (CPI-0610) Monotherapy in Patients with Myelofibrosis - Update of Clinical and Translational Data from the Ongoing Manifest Trial

Marina Kremyanskaya, John Mascarenhas, Francesca Palandri, Alessandro Vannucchi, Srdan Verstovsek, Claire N. Harrison, Prithviraj Bose, Gary J. Schiller, Raajit Rampal, Mark W. Drummond, Vikas Gupta, Andrea Patriarca, Nikki Granacher, Joseph Scandura, Witold Prejzner, Lino L. Teichmann, Natalia Curto-Garcia, Ronald Hoffman, Gozde Colak, Zheng Ren, Suresh Bobba, Jike Cui, Sergey Efuni, Moshe Talpaz
Journal: Blood
Blood (2021) 138 (Supplement 1): 141.
https://doi.org/10.1182/blood-2021-150172
Published: 2021
Journal Articles

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea

Clinical Trials & Observations
Abdulraheem Yacoub, John Mascarenhas, Heidi Kosiorek, Josef T. Prchal, Dmitry Berenzon, Maria R. Baer, Ellen Ritchie, Richard T. Silver, Craig Kessler, Elliott Winton, Maria Chiara Finazzi, Alessandro Rambaldi, Alessandro M. Vannucchi, David Leibowitz, Damiano Rondelli, Murat O. Arcasoy, Rosalind Catchatourian, Joseph Vadakara, Vittorio Rosti, Elizabeth Hexner, Marina Kremyanskaya, Lonette Sandy, Joseph Tripodi, Vesna Najfeld, Noushin Farnoud, Elli Papaemmanuil, Mohamed Salama, Rona Singer-Weinberg, Raajit Rampal, Judith D. Goldberg, Tiziano Barbui, Ruben Mesa, Amylou C. Dueck, Ronald Hoffman
Journal: Blood
Blood (2019) 134 (18): 1498–1509.
https://doi.org/10.1182/blood.2019000428
Published: 2019
Includes: Supplemental data
Journal Articles

Oral idasanutlin in patients with polycythemia vera

Clinical Trials & Observations
John Mascarenhas, Min Lu, Heidi Kosiorek, Elizabeth Virtgaym, Lijuan Xia, Lonette Sandy, Ruben Mesa, Bruce Petersen, Noushin Farnoud, Vesna Najfeld, Raajit Rampal, Amylou Dueck, Ronald Hoffman
Journal: Blood
Blood (2019) 134 (6): 525–533.
https://doi.org/10.1182/blood.2018893545
Published: 2019
Includes: Supplemental data
Journal Articles

Survival Advantage to Allogeneic Transplant in Patients with Myelofibrosis with Intermediate-1 or Higher DIPSS Score

Krisstina L. Gowin, DO, Karen K. Ballen, MD, Kwang Woo Ahn, PhD, Zhen-Huan Hu, MPH, Ying Liu, PhD, Lucia Masarova, MD, Srdan Verstovsek, MD PhD, Maria Coakley, Tania Jain, MBBS, Andrew Kuykendall, MD, Rami Komrokji, MD, Martha Wadleigh, MD, Sarah Patches, Murat Arcasoy, MD, Michael Green, Malathi Kandarpa, PhD, Moshe Talpaz, MD, Haris Ali, MD, Vikas Gupta, MD FRCP, FRCPath, Rebecca Devlin, Laura C. Michaelis, MD, Gabriela S. Hobbs, MD, Brady Lee Stein, MD, Ashley Pariser, MD, Aaron T. Gerds, MDMS, Kierstin Kuber, Raajit Rampal, Edwin P. Alyea, III, MD, Uday Popat, MD, Ronald Sobecks, MD, Bart L Scott, MD, Ruben Mesa, MD, Wael Saber, MD MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4288.
https://doi.org/10.1182/blood-2018-99-119002
Published: 2018
Journal Articles

Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis

Elodie Pronier, Robert L. Bowman, Jihae Ahn, Jacob Glass, Cyriac Kandoth, Tiffany R. Merlinsky, Justin T. Whitfield, Benjamin H. Durham, Antoine Gruet, Amritha Varshini Hanasoge Somasundara, Raajit Rampal, Ari Melnick, Richard P. Koche, Barry S. Taylor, Ross L. Levine
Journal: Blood
Blood (2018) 132 (12): 1265–1278.
https://doi.org/10.1182/blood-2018-03-837468
Published: 2018
Includes: Supplemental data
Journal Articles

High prevalence of myeloid neoplasms in adults with non–Langerhans cell histiocytosis

Matthias Papo, Eli L. Diamond, Fleur Cohen-Aubart, Jean-François Emile, Damien Roos-Weil, Nishant Gupta, Benjamin H. Durham, Neval Ozkaya, Ahmet Dogan, Gary A. Ulaner, Raajit Rampal, Jean-Emmanuel Kahn, Thomas Sené, Frédéric Charlotte, Baptiste Hervier, Caroline Besnard, Olivier A. Bernard, Catherine Settegrana, Nathalie Droin, Zofia Hélias-Rodzewicz, Zahir Amoura, Omar Abdel-Wahab, Julien Haroche
Journal: Blood
Blood (2017) 130 (8): 1007–1013.
https://doi.org/10.1182/blood-2017-01-761718
Published: 2017
Includes: Supplemental data
Journal Articles

Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells

Brief Report
Benjamin H. Durham, Damien Roos-Weil, Claude Baillou, Fleur Cohen-Aubart, Akihide Yoshimi, Makoto Miyara, Matthias Papo, Zofia Hélias-Rodzewicz, Nathalie Terrones, Neval Ozkaya, Ahmet Dogan, Raajit Rampal, Fanny Urbain, Lucie Le Fèvre, Eli L. Diamond, Christopher Y. Park, Thomas Papo, Frédéric Charlotte, Guy Gorochov, Valérie Taly, Olivier A. Bernard, Zahir Amoura, Omar Abdel-Wahab, François M. Lemoine, Julien Haroche, Jean-François Emile
Journal: Blood
Blood (2017) 130 (2): 176–180.
https://doi.org/10.1182/blood-2016-12-757377
Published: 2017
Includes: Supplemental data
Journal Articles

JAK2 inhibitors do not affect stem cells present in the spleens of patients with myelofibrosis

Xiaoli Wang, Fei Ye, Joseph Tripodi, Cing Siang Hu, Jiajing Qiu, Vesna Najfeld, Jesse Novak, Yan Li, Raajit Rampal, Ronald Hoffman
Journal: Blood
Blood (2014) 124 (19): 2987–2995.
https://doi.org/10.1182/blood-2014-02-558015
Published: 2014
Includes: Supplemental data