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Paul Yeh
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Journal Articles

Efficacy and safety of the LSD1 inhibitor bomedemstat in participants with polycythemia vera (PV) resistant or intolerant to cytoreductive therapy: The Phase 2 shorespan-004 study

Free
Lindsay Rein, Alice Livings, Rebecca Frewin, Andrew Innes, Ali Mahdi, Ciro Rinaldi, Natalia Curto-Garcia, Jennifer Vaughn, Joseph Shatzel, Paul Yeh, Jessica Flynn, Jonas Jutzi, Patricia Marinello, Michael Leahy
Journal: Blood
Blood (2025) 146 (Supplement 1): 83.
https://doi.org/10.1182/blood-2025-83
Published: 2025
Journal Articles

First results from the Phase 1 study of APL-4098, an oral potent GCN2 inhibitor for the treatment of Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) and Myelodysplastic Syndromes (MDS)/AML

Free
Shaun Fleming, Shuhying Tan, Mridula Mokoonlall, Andrew McQuillan, Paul Yeh, Hun Chuah, Rueben Amofa, Laurie Green, Paola Paganoni, Misba Beerahee, Brian Hamilton, Nadine Clemo, Sanjay Aggarwal, Richard Dillon
Journal: Blood
Blood (2025) 146 (Supplement 1): 6945.
https://doi.org/10.1182/blood-2025-6945
Published: 2025
Journal Articles

Nuvisertib, an oral investigational selective PIM1 kinase inhibitor, showed clinical responses strongly correlating with cytokine modulation in patients with relapsed/refractory myelofibrosis in the ongoing global phase I/II study

Free
Lindsay Rein, Firas El Chaer, Junichiro Yuda, Joseph Scandura, Shuichi Shirane, Kazuya Shimoda, Prithviraj Bose, Akiyoshi Takami, Alessandra Iurlo, Michiko Ichii, James McCloskey, Michael Keng, Samah Alimam, Noriko Fukuhara, Nikki Granacher, Giulia Benevolo, Alessandro Lucchesi, Tamanna Haque, Jean-Jacques Kiladjian, Srinivas Tantravahi, Pankit Vachhani, Anand Patel, Stanley Cheung, Paul Yeh, Francesca Palandri, Ashwin Kishtagari, Ciro Rinaldi, Marcello Rotta, Vincent Ribrag, Michael Loschi, Idoroenyi Amanam, Terrence Bradley, Karen Ansaldo, Masataka Seki, Guia Guffanti, Jinny Lee, Prasanthi Pellakuru, Zhonggai Li, Jason Foulks, Sujan Kabir, Jatin Shah, Raajit Rampal
Journal: Blood
Blood (2025) 146 (Supplement 1): 2018.
https://doi.org/10.1182/blood-2025-2018
Published: 2025
Journal Articles

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation

Open Access
Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Aaron Gallego-Crespo, Malte A. Behrendt, Maria Saura-Pañella, Aarti Tarkar, Benedict Schubert, Haiyang Yun, Sarah J. Horton, Shuchi Agrawal-Singh, Patricia S. Haehnel, Faisal Basheer, Dave Lugo, Ioanna Eleftheriadou, Olena Barbash, Arindam Dhar, Michael W. M. Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Paul Yeh, Mark A. Dawson, Rab K. Prinjha, Brian J. P. Huntly, Daniel Sasca
Journal: Blood
Blood (2025) 145 (7): 748–764.
https://doi.org/10.1182/blood.2022019306
Published: 2025
Includes: Supplemental data
Journal Articles

Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation

Free
Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Aarón Gallego-Crespo, Malte Andreas Behrendt, Maria Saura-Pañella, Benedict Schubert, Haiyang Yun, Sarah J Horton, Shuchi Agrawal Singh, Patricia S Hähnel, Faisal Basheer, Dave Lugo, Michael Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Paul Yeh, Mark A. Dawson, Rab Prinjha, Brian J P Huntly, Daniel Sasca
Journal: Blood
Blood (2024) 144 (Supplement 1): 722.
https://doi.org/10.1182/blood-2024-202515
Published: 2024
Journal Articles

Molecular disease monitoring using circulating tumor DNA in myelodysplastic syndromes

Free
Clinical Trials & Observations Brief Report
Paul Yeh, Michael Dickinson, Sarah Ftouni, Tane Hunter, Devbarna Sinha, Stephen Q. Wong, Rishu Agarwal, Ravikiran Vedururu, Kenneth Doig, Chun Yew Fong, Piers Blombery, David Westerman, Mark A. Dawson, Sarah-Jane Dawson
Journal: Blood
Blood (2017) 129 (12): 1685–1690.
https://doi.org/10.1182/blood-2016-09-740308
Published: 2017
Includes: Supplemental data
Journal Articles

Ependymal cells in cerebrospinal fluid: a traumatic occurrence

Free
Paul Yeh, David A. Westerman
Journal: Blood
Blood (2015) 125 (12): 2005.
https://doi.org/10.1182/blood-2014-11-610477
Published: 2015