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Dave Lugo
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Journal Articles

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation

Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Aaron Gallego-Crespo, Malte Andreas Behrendt, Maria Saura-Pañella, Aarti Tarkar, Benedict Schubert, Haiyang Yun, Sarah J. Horton, Shuchi Agrawal-Singh, Dr, Patricia S Hähnel, Faisal Basheer, Dave Lugo, Ioanna Eleftheriadou, Olena Barbash, Arindam Dhar, Michael Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Paul Sung-Hao Yeh, Mark A. Dawson, Rab K Prinjha, Brian JP Huntly, Daniel Sasca
Journal: Blood
Blood blood.2022019306.
https://doi.org/10.1182/blood.2022019306
Published: 2024
Includes: Supplemental data
Journal Articles

Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation

Viral Shah, George Giotopoulos, Hikari Osaki, Markus Meyerhöfer, Eshwar Meduri, Aarón Gallego-Crespo, Malte Andreas Behrendt, Maria Saura-Pañella, Benedict Schubert, Haiyang Yun, Sarah J Horton, Shuchi Agrawal Singh, Patricia S Hähnel, Faisal Basheer, Dave Lugo, Michael Kühn, Borhane Guezguez, Matthias Theobald, Thomas Kindler, Paolo Gallipoli, Paul Yeh, Mark A. Dawson, Rab Prinjha, Brian J P Huntly, Daniel Sasca
Journal: Blood
Blood (2024) 144 (Supplement 1): 722.
https://doi.org/10.1182/blood-2024-202515
Published: 2024
Journal Articles

Modelling Resistance to Emerging Epigenetic Therapies

Chun Yew Fong, MBBS FRACP FRCPA, Omer Gilan, PhD, Enid Lam, PhD, Alan Rubin, PhD, Jessica Morison, PhD, George Giotopoulos, PhD, Kym Stanley, Ftouni Sarah, MSc, Dean Tyler, Dave Lugo, Philip Jeffrey, Richard Gregory, Jaring Schreuder, Shalin Naik, PhD, Tony Kouzarides, PhD, Brian Huntly, MD PhD, Ricky W Johnstone, PhD, Rab K Prinjha, Anthony Papenfuss, PhD, Mark A Dawson, MBBS FRACP FRCPA PhD
Journal: Blood
Blood (2014) 124 (21): 3546.
https://doi.org/10.1182/blood.V124.21.3546.3546
Published: 2014
Journal Articles

Inhibition of BET Recruitment to Chromatin As An Effective Treatment for MLL-Fusion Leukaemia

Mark A Dawson, MBBS, BMedSc, FRACP, FRCPA, PhD, Rab Prinjha, Antje Dittman, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel Robson, Chun-wa Chung, Carsten Hopf, Mikhail Savitski, Konstanze Döhner, M.D., Alan K Burnett, MD, Ruud Delwel, Ph.D., Huthmacher Carola, Emma Gudgin, MBBS, MRCP, Dave Lugo, Soren Beinke, Peter Soden, Kurt R. Auger, Olivier Mirguet, Phillip Jeffrey, Gerard Drewes, Kevin Lee, Tony Kouzarides, Brian J.P. Huntly
Journal: Blood
Blood (2011) 118 (21): 55.
https://doi.org/10.1182/blood.V118.21.55.55
Published: 2011