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Tony Kouzarides
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Journal Articles

Pharmacological Inhibition of the RNA m 6 a Writer METTL3 As a Novel Therapeutic Strategy for Acute Myeloid Leukemia

Konstantinos Tzelepis, Etienne De Braekeleer, PhD MSc, Eliza Yankova, PhD, Justyna Rak, PhD, Demetrios Aspris, MSc, Ana Filipa Domingues, PhD, Richard Fosbeary, Alan Hendrick, PhD, Dan Leggate, PhD, Yaara Ofir-Rosenfeld, PhD, Alexandra Sapetschnig, PhD, Cristina Pina, MDDPhil, Mark Albertella, PhD, Wesley Blackaby, PhD, Oliver Rausch, PhD, George S. Vassiliou, FRCPath, MRCP, PhD, Tony Kouzarides, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 403.
https://doi.org/10.1182/blood-2019-127962
Published: 2019
Journal Articles

SRPK1 Is a Therapeutic Vulnerability in Acute Myeloid Leukemia through Its Effects on Alternative Isoforms of Epigenetic Regulators Including BRD4

Konstantinos Tzelepis, PhD, Etienne De Braekeleer, PhD, Isaia Barbieri, PhD, Vijay Baskar, PhD, Demetrios Aspris, MSc, Francisco Hermida Prado, PhD, Malgorzata Gozdecka, PhD, Monika Dudek, MSc, Hannes Postingl, PhD, David Bates, PhD, Andrew Bannister, PhD, Brian J.P Huntly, Cristina Pina, MDDPhil, Allan Bradley, PhD, Kosuke Yusa, PhD, Tony Kouzarides, PhD, George S. Vassiliou, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 781.
https://doi.org/10.1182/blood.V130.Suppl_1.781.781
Published: 2017
Journal Articles

Modelling Resistance to Emerging Epigenetic Therapies

Chun Yew Fong, MBBS FRACP FRCPA, Omer Gilan, PhD, Enid Lam, PhD, Alan Rubin, PhD, Jessica Morison, PhD, George Giotopoulos, PhD, Kym Stanley, Ftouni Sarah, MSc, Dean Tyler, Dave Lugo, Philip Jeffrey, Richard Gregory, Jaring Schreuder, Shalin Naik, PhD, Tony Kouzarides, PhD, Brian Huntly, MD PhD, Ricky W Johnstone, PhD, Rab K Prinjha, Anthony Papenfuss, PhD, Mark A Dawson, MBBS FRACP FRCPA PhD
Journal: Blood
Blood (2014) 124 (21): 3546.
https://doi.org/10.1182/blood.V124.21.3546.3546
Published: 2014
Journal Articles

Nuclear JAK2

Mark A. Dawson, Andrew J. Bannister, Lindsay Saunders, Omar-Abdel Wahab, Fan Liu, Stephen D. Nimer, Ross L. Levine, Berthold Göttgens, Tony Kouzarides, Anthony R. Green
Journal: Blood
Blood (2011) 118 (26): 6987–6988.
https://doi.org/10.1182/blood-2011-10-385278
Published: 2011
Journal Articles

Inhibition of BET Recruitment to Chromatin As An Effective Treatment for MLL-Fusion Leukaemia

Mark A Dawson, MBBS, BMedSc, FRACP, FRCPA, PhD, Rab Prinjha, Antje Dittman, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel Robson, Chun-wa Chung, Carsten Hopf, Mikhail Savitski, Konstanze Döhner, M.D., Alan K Burnett, MD, Ruud Delwel, Ph.D., Huthmacher Carola, Emma Gudgin, MBBS, MRCP, Dave Lugo, Soren Beinke, Peter Soden, Kurt R. Auger, Olivier Mirguet, Phillip Jeffrey, Gerard Drewes, Kevin Lee, Tony Kouzarides, Brian J.P. Huntly
Journal: Blood
Blood (2011) 118 (21): 55.
https://doi.org/10.1182/blood.V118.21.55.55
Published: 2011
Journal Articles

Directed De Novo DNA Methylation of a Genomic Locus Leads to Heritable Transcriptional Repression.

Kevin G. Ford, PhD, Paul J. Hurd, PhD, Andrew J. Bannister, PhD, Tony Kouzarides, PhD, Alexander E. Smith, PhD
Journal: Blood
Blood (2007) 110 (11): 343.
https://doi.org/10.1182/blood.V110.11.343.343
Published: 2007
Journal Articles

Both the Activity and Stability of the Transcriptional Repressor PLZF Are Modified by the Class III Histone Deacetylase SIRT1.

Melanie-Jane McConnell, PhD, Emma Langley, PhD, Yolanda Martinez-Martinez, MS, Tony Kouzarides, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2004) 104 (11): 360.
https://doi.org/10.1182/blood.V104.11.360.360
Published: 2004