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Shuhying Tan
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Journal Articles

Multicenter, Open-Label Phase 1/2a Study of Pxs-5505 and Ruxolitinib in Patients with Primary, Post-Polycythemia Vera (PV) or Post-Essential Thrombocythemia (ET) Myelofibrosis

Peter Tan, Ross Baker, Sung-Eun Lee, Anne Marie Watson, Stanley Cheung, Shang-Ju Wu, Chih-Cheng Chen, Shuhying Tan, Pankit Vachhani, Tsai-Yun Chen, Jae Hoon Lee, Hui-Hua Hsiao, Ji Yun Lee, Won Sik Lee, Lucia Masarova, Jana Baskar, Wolfgang Jarolimek, Joanna Leadbetter
Journal: Blood
Blood (2024) 144 (Supplement 1): 1001.
https://doi.org/10.1182/blood-2024-204290
Published: 2024
Journal Articles

Hematological Improvement and Other Clinical Benefits of Elritercept As Monotherapy and in Combination with Ruxolitinib in Participants with Myelofibrosis from the Ongoing Phase 2 Restore Trial

Claire Harrison, Lynette C.Y. Chee, Timothy Devos, Maria Laura Fox, Alessandra Iurlo, Francesca Palandri, David M Ross, Shuhying Tan, Alessandro Maria Vannucchi, Marielle Wondergem, Michael Pace, Hongying Wang, Ming Yang, Ying Jiang, Suresh Bobba, Montagu Hankin, Chris Materna, Christine Graham, Sanjay Thamake, Christopher Rovaldi, Dena Grayson, Jen L. Salstrom
Journal: Blood
Blood (2024) 144 (Supplement 1): 997.
https://doi.org/10.1182/blood-2024-201729
Published: 2024
Journal Articles

A Phase II Randomized Trial Comparing Low-Dose Cytarabine and Venetoclax +/- Midostaurin in Non-Adverse Cytogenetic Risk Acute Myeloid Leukemia: The ALLG AMLM25 Intervene Trial

Chong Chyn Chua, Blake Hsu, Anoop K Enjeti, Ashish Bajel, Paula Marlton, Shaun Fleming, Devendra Hiwase, Chun Kei Kris Ma, Peter J. Browett, Travis Perera, Carolyn S. Grove, Shuhying Tan, Jad Othman, Julian Cooney, Hannah Rose, Edward S Morris, Rachel Koldej, David S. Ritchie, Kate Mason, Natasha S. Anstee, John Reynolds, Andrew H Wei
Journal: Blood
Blood (2024) 144 (Supplement 1): 217.
https://doi.org/10.1182/blood-2024-199882
Published: 2024
Journal Articles

Improvements in Hematological Parameters and Quality of Life (QOL) with Elritercept (KER-050): Results from an Ongoing Phase 2 Trial in Participants with Lower-Risk (LR) Myelodysplastic Neoplasms (MDS)

Aristoteles Giagounidis, Monteserrat Arnan, Lynette C.Y. Chee, Thomas Cluzeau, Maria Diez-Campelo, Devendra Hiwase, David M Ross, Mikkael A. Sekeres, Shuhying Tan, David Valcarcel, Rena Buckstein, Bhavna Patel-Shah, Ming Yang, Ying Jiang, Jiani Yin, Suresh Bobba, Montagu Hankin, Chris Materna, Christine Graham, Sanjay Thamake, Christopher Rovaldi, Dena Grayson, Jen L. Salstrom
Journal: Blood
Blood (2024) 144 (Supplement 1): 1825.
https://doi.org/10.1182/blood-2024-203274
Published: 2024
Journal Articles

Phase 1 Safety and Efficacy of Tuspetinib Plus Venetoclax Combination Therapy in Study Participants with Relapsed or Refractory Acute Myeloid Leukemia (AML) Support Exploration of Triplet Combination Therapy of Tuspetinib Plus Venetoclax and Azacitidine for Newly Diagnosed AML

Naval Daver, Kyoo Hyung Lee, Yunsuk Choi, Pau Montesinos, Brian A. Jonas, Martha L. Arellano, Uma Borate, Justin M. Watts, Paul B. Koller, Chul Won Jung, Sang Kyun Sohn, Amir T. Fathi, Pankit Vachhani, Nikolai A. Podoltsev, Olga Salamero, Sung-Soo Yoon, Jeong-Ok Lee, Gabriel N Mannis, Shuhying Tan, Sudipto Mukherjee, Harry Erba, Ho-Jin Shin, Uwe Platzbecker, Mar Tormo, Eric Tam, Leanne Berkahn, Teresa Bernal, Donna Nguyen Haney, Jia Hu, Ranjeet Kumar Sinha, Nawazish Khan, Vivian Costa Victory, William G. Rice, Rafael Bejar
Journal: Blood
Blood (2024) 144 (Supplement 1): 4255.
https://doi.org/10.1182/blood-2024-200397
Published: 2024
Journal Articles

Hematologic Improvement and Fatigue Reduction with Elritercept (KER-050) in Participants with Lower-Risk (LR) Myelodysplastic Neoplasms (MDS) with Non-Transfusion Dependent Anemia: New Analyses from an Ongoing Phase 2 Trial

Shuhying Tan, Montserrat Arnan, Lynette C.Y. Chee, Thomas Cluzeau, Maria Diez-Campelo, Aristoteles Giagounidis, Devendra Hiwase, David M Ross, Mikkael A. Sekeres, David Valcarcel, Bhavna Patel-Shah, Ming Yang, Ying Jiang, Jiani Yin, Suresh Bobba, Montagu Hankin, Chris Materna, Christine Graham, Sanjay Thamake, Christopher Rovaldi, Dena Grayson, Jen L. Salstrom
Journal: Blood
Blood (2024) 144 (Supplement 1): 4591.
https://doi.org/10.1182/blood-2024-208186
Published: 2024
Journal Articles

Modulation of TGF-β Superfamily Signaling By Ker-050 Demonstrated Potential to Treat Myelofibrosis and Mitigate Ruxolitinib-Associated Cytopenia

Claire N Harrison, David M. Ross, Lynette C.Y. Chee, Shuhying Tan, Marielle Wondergem, Timothy Devos, Christine Graham, Allie McGinty, Michael Pace, Hongying Wang, Ying Jiang, Suresh Bobba, Katie Louise Dawson, Christopher Rovaldi, Montagu Hankin, Dena Grayson, Simon Cooper, Jen L. Salstrom
Journal: Blood
Blood (2023) 142 (Supplement 1): 3185.
https://doi.org/10.1182/blood-2023-187099
Published: 2023
Journal Articles

Ker-050 Treatment Reduced Iron Overload and Increased Bone Specific Alkaline Phosphatase in Participants with Lower-Risk MDS Supporting Potential to Restore Balance to the Osteohematopoietic Niche

Lynette C.Y. Chee, David M. Ross, Thomas Cluzeau, Shuhying Tan, Aristoteles Giagounidis, David Valcarcel, Montserrat Arnan, Maria Diez-Campelo, Christine Graham, Allie McGinty, Miranda Ross, Suresh Bobba, Wei Feng, Ying Jiang, Montagu Hankin, Christopher Rovaldi, Simon Cooper, Dena Grayson, Jen L. Salstrom
Journal: Blood
Blood (2023) 142 (Supplement 1): 1089.
https://doi.org/10.1182/blood-2023-186326
Published: 2023
Journal Articles

Durable Clinical Benefit with Ker-050 Treatment: Findings from an Ongoing Phase 2 Study in Participants with Lower-Risk MDS

Maria Diez-Campelo, David M. Ross, Aristoteles Giagounidis, Shuhying Tan, Thomas Cluzeau, Lynette C.Y. Chee, David Valcarcel, Montserrat Arnan, Christine Graham, Allie McGinty, Miranda Ross, Wei Feng, Ying Jiang, Suresh Bobba, Montagu Hankin, Christopher Rovaldi, Dena Grayson, Simon Cooper, Jen L. Salstrom
Journal: Blood
Blood (2023) 142 (Supplement 1): 196.
https://doi.org/10.1182/blood-2023-180974
Published: 2023
Journal Articles

A Phase 2, Open-Label, Ascending Dose Study of Ker-050 for the Treatment of Anemia in Patients with Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

David M Ross, Alejandro Arbelaez, Lynette C.Y. Chee, Chun Yew Fong, Devendra Hiwase, George Kannourakis, John Kwan, James Liang, Anish Puliyayil, Hannah Rose, Shuhying Tan, Tse-Chieh Teh, David Alan Westerman, Joel Wight, Chris Rovaldi, Elissa M. Furutani, Adrienne Gaggi, Ying Jiang, Jenn Lachey, Harveen Dhillon Natarajan, Claudia Ordonez
Journal: Blood
Blood (2021) 138 (Supplement 1): 3675.
https://doi.org/10.1182/blood-2021-147335
Published: 2021
Journal Articles

Altered Expression of Hoxa1 Perturbs Haematopoiesis in a Dose-Dependent Manner and Induces Myelodysplasia in Mice

Shuhying Tan, MBBS, FRACP, FRCPA, Alistair Chalk, PhD, Ana C Maluenda, Lenny Straszkowski, Jack O'Halloran, Meaghan Wall, MBBS, PhD FRACP, FRCPA, Louise E Purton, PhD
Journal: Blood
Blood (2016) 128 (22): 1132.
https://doi.org/10.1182/blood.V128.22.1132.1132
Published: 2016