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Professor Francesco Passamonti
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Journal Articles

Safety and efficacy of the mutant calreticulin-specific monoclonal antibody INCA033989 as monotherapy or in combination with ruxolitinib in patients (pts) with myelofibrosis (MF): Preliminary results from dose escalation of two global Phase 1 studies

Free
John Mascarenhas, Haifa Kathrin Al-Ali, Vikas Gupta, Haris Ali, Francesca Palandri, Professor Francesco Passamonti, Raajit Rampal, Aaron Gerds, Tania Jain, Sanjay Mohan, Steffen Koschmieder, Caroline McNamara, Andrew Perkins, Bethan Psaila, Vincent Ribrag, William Shomali, Rosa Ayala Diaz, Mikkel Helleberg Dorff, Claire Harrison, Stephen Oh, Frank Stegelmann, Alessandro Maria Vannucchi, Abdulraheem Yacoub, Jason Gotlib, Jyoti Nangalia, Chenwei Tian, Betty Lamothe, Erin Crowgey, Tatiana Zinger, Evan Braunstein, David Ross
Journal: Blood
Blood (2025) 146 (Supplement 1): 484.
https://doi.org/10.1182/blood-2025-484
Published: 2025
Journal Articles

Preliminary data from the Phase I/II study of nuvisertib, an oral investigational selective PIM1 inhibitor, in combination with momelotinib showed clinical responses in patients with relapsed/refractory myelofibrosis

Free
John Mascarenhas, Joseph Scandura, Vikas Gupta, Kazuya Shimoda, James McCloskey, Firas El Chaer, Prithviraj Bose, Raajit Rampal, Andrew Srisuwananukorn, Timothy Devos, Ruben Mesa, Professor Francesco Passamonti, Srinivas Tantravahi, David Ross, Lindsay Rein, Jean-Jacques Kiladjian, Takanori Teshima, Takuji Yamauchi, Noboru Asada, Anna Halpern, Tamanna Haque, Etienne Paubelle, Noriko Fukuhara, Pankit Vachhani, Michiko Ichii, Ronald Hoffman, Marcello Rotta, Michael Keng, Stefan Wickenhauser, Karen Ansaldo, Masataka Seki, Jinny Lee, Vincent Loksa, Zhonggai Li, Jason Foulks, Sujan Kabir, Jatin Shah, Claire Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 482.
https://doi.org/10.1182/blood-2025-482
Published: 2025
Journal Articles

Safety and efficacy of INCA033989, a novel first in class mutant calreticulin-specific monoclonal antibody, in patients with essential thrombocythemia

Free
Vikas Gupta, John Mascarenhas, Haris Ali, David Ross, Abdulraheem Yacoub, Tania Jain, Lynette Chee, Aaron Gerds, Jean-Jacques Kiladjian, Ruben Mesa, William Shomali, Makoto Yoshimitsu, Rosa Ayala Diaz, Chi-Joan How, Steffen Koschmieder, Caroline McNamara, Yosuke Nakaya, Francesca Palandri, Professor Francesco Passamonti, Andrew Perkins, Bethan Psaila, Raajit Rampal, Natasha Szuber, Frank Stegelmann, Alessandro Maria Vannucchi, Hiroki Yamaguchi, Jason Gotlib, Jyoti Nangalia, Chenwei Tian, Betty Lamothe, Erin Crowgey, Tatiana Zinger, Evan Braunstein, Claire Harrison
Journal: Blood
Blood (2025) 146 (Supplement 1): 1024.
https://doi.org/10.1182/blood-2025-1024
Published: 2025