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Journal Articles

Artificial intelligence in hematology

Aziz Nazha, Olivier Elemento, Sanjay Ahuja, Barbara Lam, Moses Miles, Roni Shouval, Shannon McWeeney, Shireen Sirhan, Andrew Srisuwananukorn, Torsten Haferlach

Blood (2025) 146 (19): 2283–2292.

https://doi.org/10.1182/blood.2025029876

Published: 2025

Journal Articles

Deep learning enables automated quantification of hematopoietic stem and progenitor cells (HSPCs) in zebrafish embryos

Xavier Vesco, Konur Oyman, Annika Chura, Wantong Li, Altan Turkoglu, Shelby Cabrera, Zhihong Lin, Meng Wu, Blake Peterson, Sharyn Baker, Andrew Srisuwananukorn, Bradley Blaser

Blood (2025) 146 (Supplement 1): 6112.

https://doi.org/10.1182/blood-2025-6112

Published: 2025

Journal Articles

Preliminary data from the Phase I/II study of nuvisertib, an oral investigational selective PIM1 inhibitor, in combination with momelotinib showed clinical responses in patients with relapsed/refractory myelofibrosis

Blood (2025) 146 (Supplement 1): 482.

https://doi.org/10.1182/blood-2025-482

Published: 2025

Journal Articles

Toxicity of reduced dose versus standard dose pegaspargase in adolescents and young adults with acute lymphoblastic leukemia

Blood (2025) 146 (Supplement 1): 3344.

https://doi.org/10.1182/blood-2025-3344

Published: 2025

Journal Articles

Ruxolitinib and interferon alfa induce superior rates of complete peripheral blood count remission compared to anagrelide in hydroxyurea-exposed essential thrombocythemia

Tripura Vithala, Seungyeon Lee, Haley Roberts, Shivani Handa, Jennifer Vaughn, Sarah Wall, Ping Zhang, Andrew Srisuwananukorn

Blood (2025) 146 (Supplement 1): 3824.

https://doi.org/10.1182/blood-2025-3824

Published: 2025

Journal Articles

Deep learning predicts IDH1 mutation status in Acute Myeloid Leukemia from bone marrow smear images

Jan-Niklas Eckardt, Ishan Srivastava, Chethan Babu, Sebastian Riechert, Tim Schmittmann, Susann Winter, Martin Schneider, Markus Badstübner, Ann-Kathrin Eisfeld, Haley Roberts, Christoph Röllig, Martin Bornhäuser, Jan Moritz Middeke, Andrew Srisuwananukorn

Blood (2025) 146 (Supplement 1): 2558.

https://doi.org/10.1182/blood-2025-2558

Published: 2025

Journal Articles

Real World Outcomes of Patients (Pts) with Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) or Therapy-Related AML (t-AML) Receiving Venetoclax-Based Therapies

Kelly Pugh, Michael C Walker, Deedra Nicolet, Victoria Klein, Krzysztof Mrózek, Gregory K Behbehani, James S. Blachly, Uma Borate, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Andrew Srisuwananukorn, Ann-Kathrin Eisfeld, Alice Mims

Blood (2024) 144 (Supplement 1): 7929.

https://doi.org/10.1182/blood-2024-210135

Published: 2024

Journal Articles

Accelerating Drug Discovery: AI-Powered Indication Exploration for Ropeginterferon Alfa-2b

Erik R Sampson, Yi-Chien Chang, Kuan-Chun Huang, Tom Lin, Prasanna Baskar, Mei-Ling Yang, Ali Sepahi, Dobeen Hwang, Jack Huck, Ming-Tang Chen, Emily Huang, Ivana Grbesa, Francesco Lamanna, Andreas Kramer, Andrew Srisuwananukorn, Lih-Ling Lin

Blood (2024) 144 (Supplement 1): 4982.

https://doi.org/10.1182/blood-2024-210640

Published: 2024

Journal Articles

Comparison of Two Myeloablative Total-Body Irradiation (MAC-TBI) Regimens: 1200 Cgy Vs 800 Cgy of TBI for Allogeneic Stem Cell Transplantation in Adults with Hematological Malignancies

Blood (2024) 144 (Supplement 1): 7303.

https://doi.org/10.1182/blood-2024-194146

Published: 2024

Journal Articles

GATA2 -Mutated AML: Clinical Outcomes and Spectrum of Infections in Patients Undergoing or Not Allogeneic Stem Cell Transplantation

Blood (2024) 144 (Supplement 1): 7309.

https://doi.org/10.1182/blood-2024-202650

Published: 2024

Journal Articles

Second Primary Hematological Malignancy in Multiple Myeloma Patients Exposed to Lenalidomide and Autologous Stem Cell Transplantation

Justin Jiang, Joshua Galloway, Andrew Srisuwananukorn, Uma Borate, Nidhi Sharma, Naresh Bumma, Srinivas Devarakonda, Elvira Umyarova, Ashley Rosko, Abdullah Mohammad Khan, Don Benson, Francesca Cottini

Blood (2024) 144 (Supplement 1): 6954.

https://doi.org/10.1182/blood-2024-198754

Published: 2024

Journal Articles

Real-World Experience of Venetoclax Target Dosing with Concomitant Posaconazole in Adult Patients with Acute Myeloid Leukemia

Blood (2024) 144 (Supplement 1): 2432.

https://doi.org/10.1182/blood-2024-203704

Published: 2024

Journal Articles

A Phase I Study to Evaluate the Safety and Tolerability of Gemtuzumab Ozogamicin and Midostaurin When Used in Combination with Standard Cytarabine and Daunorubicin Induction for Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia

Uma Borate, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Roland B. Walter, Rachel J. Cook, Jennifer N. Saultz, Ronan T. Swords, Nicole R. Grieselhuber, Alice Mims, Karilyn T. Larkin, Kieran D Sahasrabudhe, James S. Blachly, Gregory K Behbehani, Ann-Kathrin Eisfeld, Meixiao Long, Andrew Srisuwananukorn, Kristin L Koenig

Blood (2024) 144 (Supplement 1): 4286.

https://doi.org/10.1182/blood-2024-210605

Published: 2024

Journal Articles

Oral Decitabine/Cedazuridine Is a Tolerable and Effective Ambulatory Regimen for Patients with Advanced Myeloproliferative Neoplasms

Ganesh Sivakumar, Shivani Handa, Andrew Srisuwananukorn, Douglas Tremblay, John Mascarenhas, Marina Kremyanskaya, Yelena Ginzburg, Xiaoli Wang, Ronald Hoffman

Blood (2023) 142 (Supplement 1): 1828.

https://doi.org/10.1182/blood-2023-178822

Published: 2023

Journal Articles

Prevalence and Prediction of Ruxolitinib Treatment Emergent Thrombocytopenia in Myelofibrosis

Douglas Tremblay, Zaker I. Schwabkey, Yosef Joseph Rene Amel Riazat-Kesh, Grace Van Hyfte, Najla H Al Ali, Julian Waksal, Andrew Srisuwananukorn, Rami S. Komrokji, John Mascarenhas, Andrew T. Kuykendall

Blood (2023) 142 (Supplement 1): 1830.

https://doi.org/10.1182/blood-2023-179937

Published: 2023

Journal Articles

Interpretable Artificial Intelligence (AI) Differentiates Prefibrotic Primary Myelofibrosis (prePMF) from Essential Thrombocythemia (ET): A Multi-Center Study of a New Clinical Decision Support Tool

Andrew Srisuwananukorn, Giuseppe Gaetano Loscocco, Andrew T. Kuykendall, James M Dolezal, Raffaella Santi, Ling Zhang, Avani M Singh, Paola Guglielmelli, Alessandro Maria Vannucchi, Douglas Tremblay, Alexander T Pearson, Mohamed E. Salama, Ronald Hoffman

Blood (2023) 142 (Supplement 1): 901.

https://doi.org/10.1182/blood-2023-173877

Published: 2023

Journal Articles

Predictors and Clinical Complications Associated with Antiphospholipid Antibodies in Sickle Cell Disease

Claudia Rodriguez Rivera, Andrew Srisuwananukorn, Rizma Jalees Bajwa, Victor R. Gordeuk, Joyce Rauch, Jerrold Levine, Santosh L. Saraf

Blood (2022) 140 (Supplement 1): 8278–8279.

https://doi.org/10.1182/blood-2022-163851

Published: 2022

Journal Articles

Novel Machine Learning Algorithm Predicts Disease Progression in Polycythemia Vera (PV) with Readily-Available Baseline Characteristics

Blood (2021) 138 (Supplement 1): 2583.

https://doi.org/10.1182/blood-2021-150561

Published: 2021

Journal Articles

Defining and Predicting Rapid Egfr Decline in Sickle Cell Disease

Santosh L. Saraf, Jin Han, Maria Armila Ruiz, Andrew Srisuwananukorn, David Shuey, Faiz Ahmed Hussain, Franklin Njoku, Robert E. Molokie, Victor R. Gordeuk

Blood (2021) 138 (Supplement 1): 122.

https://doi.org/10.1182/blood-2021-147861

Published: 2021

Journal Articles

European Leukemianet (ELN) Response Predicts Disease Progression but Not Thrombosis or Death in Polycythemia Vera (PV): An Analysis of a Multicenter Database

Douglas Tremblay, Andrew Srisuwananukorn, Lukas Ronner, Nikolai Podoltsev, Jason Gotlib, Mark L. Heaney, Andrew T. Kuykendall, Casey L. O'Connell, Jamile M. Shammo, Angela Fleischman, Ruben A. Mesa, Abdulraheem Yacoub, Ronald Hoffman, Erin Moshier, Nicole Zubizarreta, John Mascarenhas

Blood (2021) 138 (Supplement 1): 240.

https://doi.org/10.1182/blood-2021-148020

Published: 2021

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Artificial intelligence in hematology

Deep learning enables automated quantification of hematopoietic stem and progenitor cells (HSPCs) in zebrafish embryos

Preliminary data from the Phase I/II study of nuvisertib, an oral investigational selective PIM1 inhibitor, in combination with momelotinib showed clinical responses in patients with relapsed/refractory myelofibrosis

Toxicity of reduced dose versus standard dose pegaspargase in adolescents and young adults with acute lymphoblastic leukemia

Ruxolitinib and interferon alfa induce superior rates of complete peripheral blood count remission compared to anagrelide in hydroxyurea-exposed essential thrombocythemia

Deep learning predicts IDH1 mutation status in Acute Myeloid Leukemia from bone marrow smear images

Real World Outcomes of Patients (Pts) with Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) or Therapy-Related AML (t-AML) Receiving Venetoclax-Based Therapies

Accelerating Drug Discovery: AI-Powered Indication Exploration for Ropeginterferon Alfa-2b

Comparison of Two Myeloablative Total-Body Irradiation (MAC-TBI) Regimens: 1200 Cgy Vs 800 Cgy of TBI for Allogeneic Stem Cell Transplantation in Adults with Hematological Malignancies

GATA2 -Mutated AML: Clinical Outcomes and Spectrum of Infections in Patients Undergoing or Not Allogeneic Stem Cell Transplantation

Second Primary Hematological Malignancy in Multiple Myeloma Patients Exposed to Lenalidomide and Autologous Stem Cell Transplantation

Real-World Experience of Venetoclax Target Dosing with Concomitant Posaconazole in Adult Patients with Acute Myeloid Leukemia

A Phase I Study to Evaluate the Safety and Tolerability of Gemtuzumab Ozogamicin and Midostaurin When Used in Combination with Standard Cytarabine and Daunorubicin Induction for Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia

Oral Decitabine/Cedazuridine Is a Tolerable and Effective Ambulatory Regimen for Patients with Advanced Myeloproliferative Neoplasms

Prevalence and Prediction of Ruxolitinib Treatment Emergent Thrombocytopenia in Myelofibrosis

Interpretable Artificial Intelligence (AI) Differentiates Prefibrotic Primary Myelofibrosis (prePMF) from Essential Thrombocythemia (ET): A Multi-Center Study of a New Clinical Decision Support Tool

Predictors and Clinical Complications Associated with Antiphospholipid Antibodies in Sickle Cell Disease

Novel Machine Learning Algorithm Predicts Disease Progression in Polycythemia Vera (PV) with Readily-Available Baseline Characteristics

Defining and Predicting Rapid Egfr Decline in Sickle Cell Disease

European Leukemianet (ELN) Response Predicts Disease Progression but Not Thrombosis or Death in Polycythemia Vera (PV): An Analysis of a Multicenter Database

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