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Karilyn T. Larkin
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Journal Articles

Initial Results of a First-in-Human, Phase I Study Point-of-Care Manufacturing of Trispecific CAR-T Cells Targeting CD19/20/22 in B-Cell Malignancies

Sumithira Vasu, Evandro Bezerra, Nathan Denlinger, Nicole Szuminski, Dina Schneider, Pradyot Dash, Louisa Wirthlin, Narendranath Epperla, Yazeed Sawalha, Jennifer A. Woyach, Kerry A. Rogers, Seema A Bhat, Gregory K Behbehani, Karilyn T. Larkin, Adam S Kittai, Wing Chan, Ashley Angell Krull, Shamama Nishat, Lynn O'Donnell, Lapo Alinari, Marcos de Lima
Journal: Blood
Blood (2024) 144 (Supplement 1): 2078.
https://doi.org/10.1182/blood-2024-207532
Published: 2024
Journal Articles

Superiority of Post-Transplant Cyclophosphamide-Based Graft Versus Host Disease (GvHD) Prophylaxis in Patients 70 Years and Older: A BMT CTN 1703 Post-Hoc Analysis

Sameem Abedin, Qinghua Lian, Michael J Martens, MHD Monzr M. Al Malki, Hany Elmariah, Mahasweta Gooptu, Karilyn T. Larkin, Brian C. Shaffer, Alison W Loren, Melhem M. Solh, Amin M. Alousi, Omer Jamy, Janny M. Yao, Kristy Applegate, Miguel Angel Perales, Leslie Kean, Yvonne A. Efebera, Ran Reshef, William Clark, Eric Leifer, Mary M. Horowitz, Richard J. Jones, Javier Bolanos-Meade, Shernan G. Holtan, Mehdi Hamadani
Journal: Blood
Blood (2024) 144 (Supplement 1): 1042.
https://doi.org/10.1182/blood-2024-193827
Published: 2024
Journal Articles

Comparison of Two Myeloablative Total-Body Irradiation (MAC-TBI) Regimens: 1200 Cgy Vs 800 Cgy of TBI for Allogeneic Stem Cell Transplantation in Adults with Hematological Malignancies

Gabriela Sanchez-Petitto, Ying Huang, Evandro Bezerra, Jonathan E. Brammer, Hannah Choe, Nathan Denlinger, Polina Shindiapina, Sam Penza, Sarah A Wall, Gregory K Behbehani, James S. Blachly, Bradley Wayne Blaser, Uma Borate, Ann-Kathrin Eisfeld, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Ayman Saad, Sumithira Vasu, Marcos de Lima
Journal: Blood
Blood (2024) 144 (Supplement 1): 7303.
https://doi.org/10.1182/blood-2024-194146
Published: 2024
Journal Articles

GATA2 -Mutated AML: Clinical Outcomes and Spectrum of Infections in Patients Undergoing or Not Allogeneic Stem Cell Transplantation

Gabriela Sanchez-Petitto, Zeinab El Boghdadly, Deedra Nicolet, Julia Cooper, Ann-Kathrin Eisfeld, Victoria Klein, Michael C Walker, Krzysztof Mrózek, Evandro Bezerra, Jonathan E. Brammer, Nathan Denlinger, Polina Shindiapina, Sam Penza, Sarah A. Wall, Gregory K Behbehani, James S. Blachly, Bradley Wayne Blaser, Uma Borate, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Sumithira Vasu, Marcos de Lima
Journal: Blood
Blood (2024) 144 (Supplement 1): 7309.
https://doi.org/10.1182/blood-2024-202650
Published: 2024
Journal Articles

Real World Outcomes of Patients (Pts) with Acute Myeloid Leukemia, Myelodysplasia-Related (AML-MR) or Therapy-Related AML (t-AML) Receiving Venetoclax-Based Therapies

Kelly Pugh, Michael C Walker, Deedra Nicolet, Victoria Klein, Krzysztof Mrózek, Gregory K Behbehani, James S. Blachly, Uma Borate, Nicole R. Grieselhuber, Kristin L Koenig, Karilyn T. Larkin, Meixiao Long, Andrew Srisuwananukorn, Ann-Kathrin Eisfeld, Alice Mims
Journal: Blood
Blood (2024) 144 (Supplement 1): 7929.
https://doi.org/10.1182/blood-2024-210135
Published: 2024
Journal Articles

A Phase I Study to Evaluate the Safety and Tolerability of Gemtuzumab Ozogamicin and Midostaurin When Used in Combination with Standard Cytarabine and Daunorubicin Induction for Newly Diagnosed FLT3-Mutated Acute Myeloid Leukemia

Uma Borate, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Roland B. Walter, Rachel J. Cook, Jennifer N. Saultz, Ronan T. Swords, Nicole R. Grieselhuber, Alice Mims, Karilyn T. Larkin, Kieran D Sahasrabudhe, James S. Blachly, Gregory K Behbehani, Ann-Kathrin Eisfeld, Meixiao Long, Andrew Srisuwananukorn, Kristin L Koenig
Journal: Blood
Blood (2024) 144 (Supplement 1): 4286.
https://doi.org/10.1182/blood-2024-210605
Published: 2024
Journal Articles

Real-World Experience of Venetoclax Target Dosing with Concomitant Posaconazole in Adult Patients with Acute Myeloid Leukemia

Tracelyn Freeman, Alma Habib, Ying Huang, Pooja Kumar, Allyson Waller, Megan Fleming, Kelsey McMillan, Natalia Hartzler, Gregory K Behbehani, James S. Blachly, Bradley Wayne Blaser, Uma Borate, Ann-Kathrin Eisfeld, Nicole R. Grieselhuber, Karilyn T. Larkin, Shinae Lee, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Kieran D Sahasrabudhe, Kristin L Koenig
Journal: Blood
Blood (2024) 144 (Supplement 1): 2432.
https://doi.org/10.1182/blood-2024-203704
Published: 2024
Journal Articles

Patient-Reported Outcomes of BMT CTN 1703: A Randomized Phase III Study for Gvhd Prophylaxis - a Quality of Life Evaluation

Shernan G. Holtan, Michael J Martens, Monzr M. Al Malki, Yvonne Efebera, Carrie L. Kitko, Ran Reshef, Andrew R. Rezvani, Brian C. Shaffer, Melhem M. Solh, Janny M. Yao, Lyndsey Runaas, Hany Elmariah, Karilyn T. Larkin, Najla H El Jurdi, Mahasweta Gooptu, Alison W Loren, Aric C. Hall, Amin Alousi, Omer Jamy, William Clark, Leslie Kean, Ami S. Bhatt, Miguel-Angel Perales, Kristy Applegate, Juan WU, Eric Liefer, Nancy DiFronzo, Richard J. Jones, Mary M. Horowitz, Deborah Mattila, Mehdi Hamadani, Javier Bolanos-Meade
Journal: Blood
Blood (2023) 142 (Supplement 1): 897.
https://doi.org/10.1182/blood-2023-187859
Published: 2023
Journal Articles

Debio 1562M, a Next Generation Antibody Drug Conjugate (ADC) Targeting CD37 for AML and MDS Treatment

Lisa Ivanschitz, Josée Hue-Perron, Léo Marx, Marie-Claude Roubaudi-Fraschini, Caroline Peet, Nathalie Bellocq, Riccardo Colombo, Karilyn T. Larkin, Esthela Artiga
Journal: Blood
Blood (2023) 142 (Supplement 1): 1542.
https://doi.org/10.1182/blood-2023-180767
Published: 2023
Journal Articles

Type 3 Innate Lymphoid Cells Promote Acute Myeloid Leukemia Immune Evasion and Expansion

Thanh Thanh (Sarah) T Dinh, Matthew Lordo, Nikolas Shilo, Ekaterina S Altynova, Parker Kronen, Megan Broughton, Erin Jeremy, Karilyn T. Larkin, Christopher C. Oakes, Patrick Collins, Aharon G. Freud, Bethany L Mundy-Bosse
Journal: Blood
Blood (2023) 142 (Supplement 1): 5390.
https://doi.org/10.1182/blood-2023-181949
Published: 2023
Journal Articles

Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis

Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Samon Benrashid, Ethan C. Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Kristin L Koenig, Karilyn T. Larkin, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4070.
https://doi.org/10.1182/blood-2023-179237
Published: 2023
Journal Articles

The Ancestry-Related Landscape of Long Non-Coding RNAs (LncRNAs) in Acute Myeloid Leukemia (AML) and Its Impact on Patient (Pt) Survival

Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Andrew Stiff, Christopher J. Walker, Jill Buss, Alice Mims, Christopher C. Oakes, Karilyn T. Larkin, James S. Blachly, Andrew J Carroll, William Blum, Bayard L Powell, Jonathan E Kolitz, Richard M Stone, Geoffrey L Uy, Wendy Stock, Jennifer A. Woyach, John C. Byrd, Dimitrios Papaioannou, Ann-Kathrin Eisfeld, Kellie Archer
Journal: Blood
Blood (2023) 142 (Supplement 1): 722.
https://doi.org/10.1182/blood-2023-185030
Published: 2023
Journal Articles

A Phase 1b/2 Trial of Liposomal Cytarabine and Daunorubicin (CPX-351) in Intermediate to High-Risk Acute Myeloid Leukemia for Patients Who Have Failed an Initial Cycle of Induction Chemotherapy

Corbin Pontious, Ramiro Garzon, James S. Blachly, Bradley Wayne Blaser, Hannah Choe, Nicole R. Grieselhuber, Meixiao Long, Sumithira Vasu, Sarah A Wall, Karilyn T. Larkin, Ann-Kathrin Eisfeld, Kristin L Koenig, Kieran D Sahasrabudhe, Gabriela Sanchez-Petitto, Ayman Saad, Bhavana Bhatnagar, Justin Lyberger, Uma M. Borate, Alice Mims, Brian A. Jonas, Gregory K Behbehani
Journal: Blood
Blood (2023) 142 (Supplement 1): 5946.
https://doi.org/10.1182/blood-2023-184344
Published: 2023
Journal Articles

Post-Transplant Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil As the New Standard for Graft-Versus-Host Disease (GVHD) Prophylaxis in Reduced Intensity Conditioning: Results from Phase III BMT CTN 1703

Shernan G Holtan, Mehdi Hamadani, Juan WU, Monzr M. AL Malki, Lyndsey Runaas, Hany Elmariah, Andrew R. Rezvani, Mahasweta Gooptu, Karilyn T. Larkin, Brian C. Shaffer, Najla H El Jurdi, Alison W. Loren, Melhem Solh, Aric C. Hall, Amin M Alousi, Omer H Jamy, Miguel-Angel Perales, Janny M. Yao, Kristy Applegate, Ami S. Bhatt, Leslie S. Kean, Yvonne A. Efebera, Carrie Lynn Kitko, Ran Reshef, William Clark, Nancy L. DiFronzo, Lori Henderson, Richard J. Jones, Eric Liefer, Michael J Martens, Mary M. Horowitz, Javier Bolanos-Meade
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-4.
https://doi.org/10.1182/blood-2022-171463
Published: 2022
Journal Articles

The Multi-CDK Inhibitor Dinaciclib Shows Synergistic Activity with the BET Inhibitor PLX51107 and Reverses BET Resistance through Inhibition of Canonical Wnt Signaling in Acute Myeloid Leukemia (AML)

Alexander Marr, Soumendrakrishna Karmahapatra, Dominique Corbin, Yerdanos Asemelash, Steven Sher, Shaneice Renee Mitchell, Bonnie K Harrington, Shelley Orwick, Larry Beaver, Ronni Wasmuth, Virginia Goettl, Alice S. Mims, Karilyn T. Larkin, Sumithira Vasu, Meixiao Long, James S. Blachly, Ramiro Garzon, John C. Byrd, Rosa Lapalombella, Nicole Grieselhuber
Journal: Blood
Blood (2022) 140 (Supplement 1): 3075–3076.
https://doi.org/10.1182/blood-2022-160277
Published: 2022
Journal Articles

Elucidating the Mechanism of Action (MOA) of Navtemadlin, an MDM2 Inhibitor, and Its Synergy with Gilteritinib in Myeloid Malignancies

Sara Elgamal, Tracy Clevenger, Michael Gulrajani, Jean Cheung, Erin G. Jeremy, Sydney Fobare, Shelley Orwick, Ellen J. Sass, Erin Hertlein, Karilyn T. Larkin, Todd Covey, Wayne P. Rothbaum, John C. Byrd
Journal: Blood
Blood (2022) 140 (Supplement 1): 5936–5938.
https://doi.org/10.1182/blood-2022-159568
Published: 2022
Journal Articles

Post-Allograft Romidepsin Maintenance Mitigates Relapse Risk and Stimulates the Graft-Versus-Malignancy Effect through Enhanced NK-Cell Cytotoxicity in Patients with Aggressive T-Cell Malignancies in a Phase I/II Trial

Chitra Hosing, Eric McLaughlin, Zachary Braunstein, Benigno C Valdez, Lai Wei, Uday R Popat, Borje S Andersson, Sumithira Vasu, Karilyn T. Larkin, Samantha Jaglowski, Sam Penza, Ayman Saad, Hannah Choe, Sarah A Wall, Alex Cash, Robin Nakkula, Richard E Champlin, Marcos J.G. de Lima, Dean Anthony Lee, Jonathan E Brammer
Journal: Blood
Blood (2022) 140 (Supplement 1): 1885–1886.
https://doi.org/10.1182/blood-2022-169336
Published: 2022
Journal Articles

Sex-Associated Differences in Frequencies and Outcome Prognostication of Recurrent Molecular Features in Adults with Acute Myeloid Leukemia (AML) (AMLCG, CALGB [Alliance])

Michael P. Ozga, Deedra Nicolet, Krzysztof Mrózek, Selen Yilmaz, Jessica Kohlschmidt, Karilyn T. Larkin, James S. Blachly, Christopher C. Oakes, Jill Buss, Christopher J. Walker, Shelley Orwick, Vindi Jurinovic, Maja Rothenberg-Thurley, Annika Maria Dufour, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Marion Subklewe, Karsten Spiekermann, Andrew J. Carroll, William G. Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Robert James Mayer, Richard M. Stone, Geoffrey L. Uy, Wendy Stock, Klaus H. Metzeler, H. Leighton Grimes, John C. Byrd, Nathan Salomonis, Tobias Herold, Alice S. Mims, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2022) 140 (Supplement 1): 936–939.
https://doi.org/10.1182/blood-2022-165395
Published: 2022
Journal Articles

Characterization of Survival Outcomes and Clinical and Molecular Modulators in Adult Patients with Core-Binding Factor Acute Myeloid Leukemia (CBF-AML) Treated with Hidac Consolidation: An Alliance Legacy Study

Jonathan Hyak, Deedra Nicolet, Jessica Kohlschmidt, Kellie J. Archer, James S. Blachly, Karilyn T. Larkin, Bayard L. Powell, Jonathan E. Kolitz, Maria R. Baer, William G. Blum, Geoffrey L. Uy, Wendy Stock, Richard M. Stone, John C. Byrd, Krzysztof Mrózek, Ann-Kathrin Eisfeld, Alice S. Mims
Journal: Blood
Blood (2022) 140 (Supplement 1): 1284–1285.
https://doi.org/10.1182/blood-2022-167210
Published: 2022
Journal Articles

Outcome Prediction By the New 2022 European Leukemia Net (ELN) Genetic-Risk Classification for Adult Patients (Pts) with Acute Myeloid Leukemia (AML): An Alliance Study

Krzysztof Mrózek, Jessica Kohlschmidt, James S. Blachly, Deedra Nicolet, Andrew J. Carroll, Kellie J. Archer, Alice S. Mims, Karilyn T. Larkin, Shelley Orwick, Christopher C. Oakes, Jonathan E. Kolitz, Bayard L. Powell, William G. Blum, Guido Marcucci, Maria R. Baer, Geoffrey L. Uy, Wendy Stock, John C. Byrd, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2022) 140 (Supplement 1): 6318–6320.
https://doi.org/10.1182/blood-2022-167352
Published: 2022