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Samon Benrashid
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Journal Articles

Genome-Wide CRISPR/Cas9 Knockout Screen Reveals Novel LP-168 (Rocbrutinib) Combinations Targeting BCL-2 Protein Members for Chronic Lymphocytic Leukemia

Britten K. Gordon, Ethan C. Whipp, Lianbo Yu, Samon Benrashid, Andrew D. Mitchell, Alexander He, Jazmin Urrutia, Shrilekha Misra, Alexander R. Marr, Tzung-Huei Lai, Naina Karnati, Shanmugapriya Thangavadivel, Kerry A. Rogers, Seema A. Bhat, Nicole R. Grieselhuber, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Deepa Sampath, Rosa Lapalombella, Jennifer A. Woyach
Journal: Blood
Blood (2024) 144 (Supplement 1): 3587.
https://doi.org/10.1182/blood-2024-203522
Published: 2024
Journal Articles

Targeting Inflammation in Tet2 Mutant Clonal Hematopoiesis Via Inhibition of Brd4 Demonstrates Activity in Both Murine and Human Models

Alexander R. Marr, Madeline Halpin, Dominique L. Corbin, Britten K. Gordon, Samon Benrashid, Ethan C. Whipp, Jean Truxall, Olivia Cahn, Bethany L. Mundy-Bosse, Julia Cooper, Marina Beltrami Moreira, James S. Blachly, Uma Borate, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Journal: Blood
Blood (2024) 144 (Supplement 1): 2661.
https://doi.org/10.1182/blood-2024-203526
Published: 2024
Journal Articles

Mutational profile in previously treated patients with chronic lymphocytic leukemia progression on acalabrutinib or ibrutinib

Clinical Trials & Observations
Jennifer A. Woyach, Daniel Jones, Wojciech Jurczak, Tadeusz Robak, Árpád Illés, Arnon P. Kater, Paolo Ghia, John C. Byrd, John F. Seymour, Susan Long, Nehad Mohamed, Samon Benrashid, Tzung-Huei Lai, Gary De Jesus, Richard Lai, Gerjan de Bruin, Simon Rule, Veerendra Munugalavadla
Journal: Blood
Blood (2024) 144 (10): 1061–1068.
https://doi.org/10.1182/blood.2023023659
Published: 2024
Includes: Supplemental data
Journal Articles

Single-Cell RNA-Seq Analysis Reveals Distinct Tumor and Immunosuppressive T Cell Phenotypes in CLL Patients Treated with Ibrutinib

Shanmugapriya Thangavadivel, Shrilekha Misra, Samon Benrashid, Britten Gordon, Alexander He, Tzung-Huei Lai, Kerry A Rogers, Seema A Bhat, Adam S Kittai, John C. Byrd, James S. Blachly, Jennifer A. Woyach, Bradley Wayne Blaser
Journal: Blood
Blood (2023) 142 (Supplement 1): 3262.
https://doi.org/10.1182/blood-2023-186604
Published: 2023
Journal Articles

T Cell Dysfunction and Exhaustion in Patients with CLL: The Impact of Long Term Ibrutinib Treatment

Shanmugapriya Thangavadivel, Charlene Mao, Meixiao Long, Shrilekha Misra, Samon Benrashid, Britten Gordon, Alexander He, Tzung-Huei Lai, Kerry A Rogers, Seema A Bhat, Adam S Kittai, John C. Byrd, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 4631.
https://doi.org/10.1182/blood-2023-189755
Published: 2023
Journal Articles

Targeting Covalent and Non-Covalent Btki-Resistant CLL Using the Dual Irreversible/Reversible 4 th Generation BTK Inhibitor LP-168

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Samon Benrashid, Andrew Mitchell, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Shanmugapriya Thangavadivel, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Kerry A Rogers, Adam S Kittai, Seema A Bhat, John C. Byrd, Deepa Sampath, Rosa Lapalombella, Weiguo Han, Neil E. Kay, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 416.
https://doi.org/10.1182/blood-2023-178259
Published: 2023
Journal Articles

The PKC-β Inhibitor MS-553 Displays Preclinical Efficacy in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Shanmugapriya Thangavadivel, Samon Benrashid, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Nicole R. Grieselhuber, Kerry A Rogers, James S. Blachly, Adam S Kittai, Seema A Bhat, John C. Byrd, Michael Niesman, Kai Zhang, Deepa Sampath, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 2260.
https://doi.org/10.1182/blood-2023-182024
Published: 2023
Journal Articles

Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis

Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Samon Benrashid, Ethan C. Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Kristin L Koenig, Karilyn T. Larkin, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4070.
https://doi.org/10.1182/blood-2023-179237
Published: 2023
Journal Articles

The Novel Multitarget Small-Molecule Inhibitor SRX3177 Overcomes Ibrutinib Resistance in Mantle Cell Lymphoma

Dhananjaya Pal, Cody C. McHale, Samon Benrashid, Poornima Gourabathini, Krishnaiah Maddeboina, Kendra R. Vann, Rajeswaran Mani, Tatiana Kutateladze, Peter Martin, Maurizio Di Liberto, Selina Chen-Kiang, Steven I. Park, Donald L. Durden
Journal: Blood
Blood (2021) 138 (Supplement 1): 2262.
https://doi.org/10.1182/blood-2021-154253
Published: 2021
Journal Articles

Aurora Kinase Inhibition Overcomes Primary Venetoclax Failure and Leads to Synthetic Lethality in BCL2-Positive Lymphomas Via Upregulation of P53/P21/BAX Axis

Rajeswaran Mani, Samon Benrashid, Sarah E Teague, Scott C Jaros, Hsih-Te Yang, Lawrence J Druhan, David M Foureau, Nury M Steuerwald, Nilanjan Ghosh, Edward A. Copelan, Donald L. Durden, Belinda Avalos, Steven I. Park
Journal: Blood
Blood (2021) 138 (Supplement 1): 682.
https://doi.org/10.1182/blood-2021-146064
Published: 2021