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Journal Articles

Targeting PRMT5 in Primary Hemophagocytic Lymphohistiocytosis: A Novel Therapeutic Approach Using a Perforin-Deficient Mouse Model

Sheldon Steyn, Chia-Jo Chen, Rachel Saadey, Charlene Mao, Peggy A Scherle, Neha Bhagwat, Kris Vaddi, Eric Brooks, Robert Baiocchi, Michael B. Jordan, Polina Shindiapina
Journal: Blood
Blood (2024) 144 (Supplement 1): 809.
https://doi.org/10.1182/blood-2024-208866
Published: 2024
Journal Articles

T Cell Dysfunction and Exhaustion in Patients with CLL: The Impact of Long Term Ibrutinib Treatment

Shanmugapriya Thangavadivel, Charlene Mao, Meixiao Long, Shrilekha Misra, Samon Benrashid, Britten Gordon, Alexander He, Tzung-Huei Lai, Kerry A Rogers, Seema A Bhat, Adam S Kittai, John C. Byrd, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 4631.
https://doi.org/10.1182/blood-2023-189755
Published: 2023
Journal Articles

PRMT5 Inhibition Potentiates Anti-Tumor Immune Targeting of EBV-Driven B Cell Lymphoproliferative Disease

Elshafa Hassan Ahmed, Christoph Weigel, Rachel Saadey, Eric Brooks, Taylor Cash, Charlene Mao, Aneeq Yasin, Alexa Wandke, Ethan Baiocchi, Anna Mozhenkova, Fiona Brown, Shelby Sloan, JoBeth Helmig-Mason, Kaylee Harrison, Kris Vaddi, Peggy Scherle, Neha Bhagwat, Wing Keung Chan, Olivier Elemento, Christopher E Mason, Christopher C. Oakes, Robert A. Baiocchi, Polina Shindiapina
Journal: Blood
Blood (2022) 140 (Supplement 1): 3116–3117.
https://doi.org/10.1182/blood-2022-167988
Published: 2022
Journal Articles

PRMT5 Inhibition Reduces Autoinflammation in a Murine Model of Secondary Hemophagocytic Lymphohistiocytosis

Polina Shindiapina, Rachel Saadey, Aneeq Yasin, Charlene Mao, Alexa Wandke, Elshafa Hassan Ahmed, Ethan Baiocchi, Kris Vaddi, Peggy Scherle, Fiona Brown, Anna Mozhenkova, Ikbale El Ayachi, Austin D. Schenk, Shelby Sloan, Kaylee Harrison, JoBeth Helmig-Mason, Robert A. Baiocchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2022-170239
Published: 2022
Journal Articles

BZLF1-DEC205 Fusion Protein Enhances EBV-Protective Immunity in a Spontaneous Model of EBV-Driven Lymphoproliferative Disease

Elshafa Hassan Ahmed, DVM, Eric Brooks, Shelby Sloan, BS, Sarah Schlotter, Frankie Jeney, Charlene Mao, Polina Shindiapina, MD PhD, Salma Shire, Claire Hale, Manjusri Das, Alexander Prouty, Michael A. Caligiuri, MD, Robert A Baiocchi, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 342.
https://doi.org/10.1182/blood-2018-99-117837
Published: 2018
Journal Articles

Acute Myeloid Leukemia Alters Natural Killer Cell Maturation and Functional Activation

Bethany Mundy-Bosse, PhD, McConnell Kathleen, Charlene Mao, Elshafa Ahmed, Li Chen, Steven D Scoville, Aharon G. Freud, MD PhD, Jianhua Yu, PhD, Michael A. Caligiuri, MD
Journal: Blood
Blood (2014) 124 (21): 754.
https://doi.org/10.1182/blood.V124.21.754.754
Published: 2014
Journal Articles

Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells

Rossana Trotta, Li Chen, Stefan Costinean, Srirama Josyula, Bethany L. Mundy-Bosse, David Ciarlariello, Charlene Mao, Edward L. Briercheck, Kathleen K. McConnell, Anjali Mishra, Lianbo Yu, Carlo M. Croce, Michael A. Caligiuri
Journal: Blood
Blood (2013) 121 (16): 3126–3134.
https://doi.org/10.1182/blood-2012-12-467597
Published: 2013
Journal Articles

Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias

Nicholas A. Zorko, Kelsie M. Bernot, Susan P. Whitman, Ronald F. Siebenaler, Elshafa H. Ahmed, Gabriele G. Marcucci, Daniel A. Yanes, Kathleen K. McConnell, Charlene Mao, Chidimma Kalu, Xiaoli Zhang, David Jarjoura, Adrienne M. Dorrance, Nyla A. Heerema, Benjamin H. Lee, Gang Huang, Guido Marcucci, Michael A. Caligiuri
Journal: Blood
Blood (2012) 120 (5): 1130–1136.
https://doi.org/10.1182/blood-2012-03-415067
Published: 2012
Journal Articles

Regulation of acute graft-versus-host disease by microRNA-155

Parvathi Ranganathan, Catherine E. A. Heaphy, Stefan Costinean, Nicole Stauffer, Caroline Na, Mehdi Hamadani, Ramasamy Santhanam, Charlene Mao, Patricia A. Taylor, Sukhinder Sandhu, Gang He, Arwa Shana'ah, Gerard J. Nuovo, Alessandro Lagana, Luciano Cascione, Susanna Obad, Oliver Broom, Sakari Kauppinen, John C. Byrd, Michael Caligiuri, Danilo Perrotti, Gregg A. Hadley, Guido Marcucci, Steven M. Devine, Bruce R. Blazar, Carlo M. Croce, Ramiro Garzon
Journal: Blood
Blood (2012) 119 (20): 4786–4797.
https://doi.org/10.1182/blood-2011-10-387522
Published: 2012
Includes: Supplemental data
Journal Articles

miR-155 regulates IFN-γ production in natural killer cells

Rossana Trotta, Li Chen, David Ciarlariello, Srirama Josyula, Charlene Mao, Stefan Costinean, Lianbo Yu, Jonathan P. Butchar, Susheela Tridandapani, Carlo M. Croce, Michael A. Caligiuri
Journal: Blood
Blood (2012) 119 (15): 3478–3485.
https://doi.org/10.1182/blood-2011-12-398099
Published: 2012
Journal Articles

BCR-ABL1 Kinase Activity but Not Its Expression Is Dispensable for Ph+ Quiescent Stem Cell Survival Which Depends on the PP2A-Controlled Jak2 Activation and Is Sensitive to FTY720 Treatment

Paolo Neviani, Ph.D, Jason G Harb, Ph.D, Joshua J Oaks, B.S., Christopher Walker, B.S., Ramasamy Santhanam, Ph.D, Carolyn Paisie, B.S., Anna Eiring, Ph.D, Bin Zhang, Ph.D, Bastianella Perazzona, Ph.D, Y. Ma, Charlene Mao, Guido Marcucci, MD, Tessa L. Holyoake, PhD, FRCP, FRCPath, Stefano Volinia, MD, Jorge E. Cortes, MD, Michael A. Caligiuri, MD, Claudia Huettner, Ph.D, Robert Bittman, Ph.D, Ching-Shih Chen, Ph.D, Ralph B. Arlinghaus, PhD, Peter Hokland, MD, DMSC, Denis-Claude Roy, MD, FRCPC, Ravi Bhatia, MD, Danilo Perrotti, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 515.
https://doi.org/10.1182/blood.V116.21.515.515
Published: 2010
Journal Articles

FTY720 but Not Its Immunosuppressive Phosphorylated Form FTY720-P Exerts Anti-Leukemic Activity towards Ph(+) and Ph(−) Myeloproliferative Disorders through Reactivation of the PP2A Tumor Suppressor.

Joshua Oaks, BS, Paolo Neviani, PhD, A. Mukhopadhyay, Ramasamy Santhanam, PhD, Y. Ma, Charlene Mao, Guido Marcucci, MD, Ching-Shih Chen, Jorge Cortes, MD, Michael A. Caligiuri, M.D., Peter Hokland, Sr., Claudia Huettner, PhD, Steffen Koschmieder, MD, Jose Cancelas, MD, PhD, Roger Briesewitz, PhD, Ravi Bhatia, MD, Denis-Claude Roy, MD, Besim Ogretmen, PhD, Danilo Perrotti, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3259.
https://doi.org/10.1182/blood.V114.22.3259.3259
Published: 2009
Journal Articles

The Stage-Specific Effect of Interleukin-1 Beta (IL-1β) during Human Natural Killer Cell Development

Tiffany L Hughes, Michael Brian Becknell, M.D., Ph.D., Aharon Freud, M.D., Ph.D., Susan E Schmidt, Jianhua Yu, PhD, Charlene Mao, Mikhail Gavrilin, Ph.D., Mark Wewers, M.D., Michael A. Caligiuri, MD
Journal: Blood
Blood (2008) 112 (11): 3746.
https://doi.org/10.1182/blood.V112.11.3746.3746
Published: 2008
Journal Articles

Characterization of HDACI OSU42 as a Novel Histone Deacetylase Inhibitor in AML Cell Lines.

Jin Sun, PhD, Shujun Liu, PhD, Jianhua Yu, PhD, Min Wei, BS, Charlene Mao, PhD, Haiming Ding, PhD, Jessica Kearney, BS, LeNguyen Huynh, MS, Peter Paschka, MD, Dachun Wang, PhD, Rebecca B. Klisovic, MD, Danilo Perrotti, PhD, Ching-shih Chen, PhD, Williom George Blum, MD, Guido Marcucci, MD
Journal: Blood
Blood (2006) 108 (11): 1988.
https://doi.org/10.1182/blood.V108.11.1988.1988
Published: 2006
Journal Articles

Global Assessment of Promoter Methylation in a Murine Model of Cancer Identifies ID4 as a Putative Novel Tumor Suppressor Gene in Human Leukemia.

Li Yu, MD., Chunhui Liu, Jeff Vandeusen, Brian Becknell, Zunyan Dai, Yue-Zhong Wu, Aparna Raval, Te-Hui Liu, Wei Ding, Charlene Mao, Shujun Liu, Laura T. Smith, Stephen Lee, Laura Rassenti, Guido Marcucci, John Byrd, Michael A. Caligiuri, MD., Christoph Plass, PhD.
Journal: Blood
Blood (2004) 104 (11): 3488.
https://doi.org/10.1182/blood.V104.11.3488.3488
Published: 2004