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Journal Articles

Proteomic subtypes enrich current acute myeloid leukemia nomenclature and reflect intrinsic pathogenesis alongside aging

Open Access
Wen-Yan Cheng, Xiao Yi, Zhen-Yi Wang, Jian-Feng Li, Jun-Yi Zhang, Rui-Hong Zhang, Qian-Qian Zhang, Xiang-Qin Weng, Ting Huang, Yong-Mei Zhu, Chao Wang, Wei Yin, Jia-Nan Zhang, Hui-Yi Wu, Jun-Min Li, Hong-Ming Zhu, Li Chen, Wen-Fang Wang, Yu-Ting Dai, Chen-Xu Gao, Xuan Liu, Shan Wang, Sheng-Yue Wang, Bo Jiao, Zhu Chen, Hai Fang, Tong Yin, Yang Shen, Sai-Juan Chen
Journal: Blood
Blood (2025) 146 (22): 2681–2695.
https://doi.org/10.1182/blood.2024027692
Published: 2025
Includes: Supplemental data
Journal Articles

Prospective study of patient-reported depression, and cognitive and functional impairment, and impact on survival and induction mortality in fit adults age ≥60 years receiving intensive chemotherapy (IC) for Acute Myeloid Leukemia (AML): Prospective geriatric assessment (GA) report from ECOG-ACRIN (EA) E2906 randomized study

Free
James Foran, Li Chen, Selina Luger, Zhuoxin Sun, Heidi Klepin, Catherine Lai, David Claxton, Hillard Lazarus, Daniel Arber, Jacob Rowe, Elisabeth Paietta, Janis Racevskis, Francine Garrett-Bakelman, Yanming Zhang, Jessica Altman, Aref Al-Kali, Hong Zheng, Keith Pratz, Kristen O'Dwyer, Edward Broun, Bayard Powell, John Godwin, Yishai Ofran, Efrat Dotan, Mark Litzow, Martin Tallman, Lynne Wagner
Journal: Blood
Blood (2025) 146 (Supplement 1): 882.
https://doi.org/10.1182/blood-2025-882
Published: 2025
Journal Articles

Bone marrow biopsy characteristics at nadir after intensive induction therapy do not predict outcomes in acute myeloid leukemia (AML): An analysis of ECOG-ACRIN clinical trials

Free
Douglas Tremblay, Li Chen, Zhuoxin Sun, Chezi Ganzel, Hugo Fernandez, James Foran, Daniel Arber, Hillard Lazarus, Yanming Zhang, Elisabeth Paietta, John Bennett, Jacob Rowe, Mark Litzow, Martin Tallman, Ehab Atallah, Selina Luger
Journal: Blood
Blood (2025) 146 (Supplement 1): 871.
https://doi.org/10.1182/blood-2025-871
Published: 2025
Journal Articles

Mitoxantrone liposome, subcutaneous cytarabine and G-CSF (CMG) combined with venetoclax as first-line treatment in secondary Acute Myeloid Leukemia (sAML) or elderly AML patients: A multicenter, prospective, single-arm clinical trial with concurrent control

Free
Xiaoqian Xu, Ying Lu, Weiying Bao, Xiuhua Han, Ran An, Ying Wang, Zhiyin Liu, Jie Tian, Xingying Li, Zeying Yan, Haimin Sun, Li Chen, Sujiang Zhang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3447.
https://doi.org/10.1182/blood-2025-3447
Published: 2025
Journal Articles

Inferior survival in black AML patients treated with intensive chemotherapy in ECOG-ACRIN clinical trials is independent of cytogenetic profiles

Free
Shella Saint Fleur-Lominy, Li Chen, Zhuoxin Sun, Francine Garrett-Bakelman, Mihir Shukla, Hugo Fernandez, James Foran, Larry Cripe, Hillard Lazarus, Peter Wiernik, Jacob Rowe, Martin Tallman, Mark Litzow, Yanming Zhang, Selina Luger, Irum Khan
Journal: Blood
Blood (2025) 146 (Supplement 1): 290.
https://doi.org/10.1182/blood-2025-290
Published: 2025
Journal Articles

Effectiveness and safety profile of pola-based regimen in DLBCL Patients with high-risk factors in real world: A retrospective study in China

Free
Shuyu Li, Jianmin Yang, Xiong Ni, Li Chen, Jie Chen, Libing Wang, Lei Gao, Lili Xu, Yang Wang, Ziwei Wang, Miaomiao Liu
Journal: Blood
Blood (2025) 146 (Supplement 1): 7222.
https://doi.org/10.1182/blood-2025-7222
Published: 2025
Journal Articles

Toxicities on the E1910 phase III randomized trial of blinatumomab plus chemotherapy in adults with BCR:ABL-1 negative acute lymphoblastic leukemia

Free
Anjali Advani, Li Chen, Zhuoxin Sun, Ryan Mattison, Elisabeth Paietta, Yanming Zhang, Janis Racevskis, Hillard Lazarus, Jacob Rowe, Dan Arber, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent Wood, Keith Pratz, Shira Dinner, Noelle Frey, Steven Gore, Bhavana Bhatnagar, Ehab Atallah, Geoffrey Uy, Deepa Jeyakumar, Tara Lin, Cheryl Willman, Nikolai Podoltsev, Daniel Deangelo, Shejal Patel, Michelle Elliott, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry Erba, Richard Stone, Selina Luger, Charles Mullighan, Martin Tallman, Mark Litzow
Journal: Blood
Blood (2025) 146 (Supplement 1): 5120.
https://doi.org/10.1182/blood-2025-5120
Published: 2025
Journal Articles

Beyond the trial: Real-world CRS, icans, and healthcare burden of CAR T-cell therapy across US oncology practices

Free
Taiga Nishihori, Li Chen, Benjamin Wagner, Niquelle Wadé, Selina Radlein, Spencer Langerman, Trong Le, Ahmed Sawas, Christina Fullerton
Journal: Blood
Blood (2025) 146 (Supplement 1): 6263.
https://doi.org/10.1182/blood-2025-6263
Published: 2025
Journal Articles

Ruxolitinib combined with dexamethasone is a promising prophylaxis method for differentiation syndrome in acute promyelocytic leukemia (APL2022)

Free
Hongming Zhu, Yubing Zhao, Xiaojing Lin, Li Chen, Fangyi Dong, Jiong Hu, Junmin Li, Yang Shen
Journal: Blood
Blood (2025) 146 (Supplement 1): 5214.
https://doi.org/10.1182/blood-2025-5214
Published: 2025
Journal Articles

Epidemiology, clinical features, and molecular basis of TTMV :: RARA -driven acute promyelocytic leukemia

Available to Purchase
Xiaosu Zhou, Jiaqi Chen, Yan-Lai Tang, Haibo Sun, Qihui Chen, Xue Chen, Yang Zhang, Jiancheng Fang, Panxiang Cao, Xiaoli Ma, Li Chen, Yangyang Xie, Lijun Wen, Li-Bin Huang, Zhong Fan, Jiacheng Lou, Wenning Xu, Nan Zhang, Jing Li, Yu Luo, Yan Dai, Huan Du, Kun Yang, Zhixu He, Xiaoyan Yang, Linya Wang, Bing Liu, Danna Lin, Yajie Zhang, Fang Xu, Min Zhang, Yang Wang, Shu Yan, Hua Nan, Jing Zhang, Li Xu, Xiujuan Ma, Ruijie Tang, Fang Wang, Lili Yuan, Ming Liu, Lei Wang, Qisheng Wu, Lina Zhang, Siyuan Liu, Chengcheng Yan, Jianfeng Zhou, Fanyong Lyu, Ping Wu, Tong Wang, Xian Zhang, Yue Lu, Deyan Liu, Junfang Yang, Min Xiong, Yanli Zhao, Gaowei Fan, Xia Xiao, Futian Ma, Lihua Yang, Xue-Qun Luo, Junmin Li, Shuhong Shen, Huyong Zheng, Suning Chen, Hongwei Chen, Jianhong Zhao, Zhanglin Zhang, Kankan Wang, Peihua Lu, Hongxing Liu
Journal: Blood
Blood (2025) 146 (18): 2229–2243.
https://doi.org/10.1182/blood.2025028674
Published: 2025
Includes: Supplemental data
Journal Articles

The Evolution of Treatments and Outcomes for Real-World Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Chinese National Medical Center: Over 10 Years of Experience with 370 Patients

Free
Ran An, Wen Jin, Xiangqin Weng, Kankan Wang, Sujiang Zhang, Li Chen, Jianqing Mi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6790.
https://doi.org/10.1182/blood-2024-207401
Published: 2024
Journal Articles

Comprehensive Clinical and Molecular Characterization Reveals Rara As the Most Frequent Torque Teno Mini Virus Insertion Site and Defines a Distinct Ttmv::Rara Driven APL-like Leukemia Subtype

Free
Shu Sun, Yongjing Liu, Qing-Yu Xu, Xiaosu Zhou, Lijun Wen, Li Chen, Jiaqi Chen, Huili Wang, Xue Chen, Jiacheng Lou, Huyong Zheng, Yangyang Xie, Linya Wang, Futian Ma, Lihua Yang, Xianjing Wang, Wen Gao, Yin Wu, Leping Zhang, Shuhong Shen, Suning Chen, Kankan Wang, Hongxing Liu, Jinyan Huang, Hong-Hu Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1547.
https://doi.org/10.1182/blood-2024-202323
Published: 2024
Journal Articles

Prognostic Implications of KMT2A Rearrangements and Partial Tandem Duplications in AML: Outcomes and the Role of Allogeneic Hematopoietic Cell Transplantation

Free
Li Chen, Yongmei Zhu, Lingling Zhao, Jianfeng Li, Ran An, Zhiyin Liu, Xiaoqian Xu, Sujiang Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4291.
https://doi.org/10.1182/blood-2024-200787
Published: 2024
Journal Articles

Ixazomib Based Regimens As Front-Line Treatment in Newly Diagnosed Multiple Myeloma Patients in China: A Real-World Data from Infinite Study

Free
Fu Cheng Cheng, Song Jin, Junling Zhuang, Xin Zhou, Fan Zhou, Yuhua Li, Kaiyang Ding, Ting Niu, Wenming Chen, Baijun Fang, Li-Li Chen, Rong Fu, Hao Zhang, Jiaping Fu, Xiuju Wang, Sha Liu, Lin Li, Depei Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6970.
https://doi.org/10.1182/blood-2024-204366
Published: 2024
Journal Articles

Gilteritinib Results in Higher Remission and Transplant Rates Than Midostaurin but Does Not Increase the Post-Induction Mutational MRD Negative Rate: Results of the Phase 2 Randomized Precog 0905 Study in Newly Diagnosed FLT3 Mutated AML

Free
Selina Luger, Li Chen, Keith W. Pratz, Sanam Loghavi, Alexander E. Perl, Jessica K. Altman, Robert L. Redner, Amir T. Fathi, Ayman Qasrawi, Adam S. Asch, Deepa Jeyakumar, James M. Foran, Mithun V Shah, Jonathan E Kolitz, Ellin Berman, Lindsay Wilde, Sameem Abedin, Vamsi K. Kota, Krishna Gundabolu, Kristen M. O'Dwyer, Emily K Curran, Ashwin Kishtagari, Kelly Ross, Zhuoxin Sun, Mark R. Litzow
Journal: Blood
Blood (2024) 144 (Supplement 1): 221.
https://doi.org/10.1182/blood-2024-201595
Published: 2024
Journal Articles

Comparison of Standard-Dose Versus Fixed-Dose Rituximab for Non-Malignant, Immune-Mediated Hematologic Disorders

Free
Raj S. Kasthuri, Ryan Kemper, Brittany Holshouser, Elizabeth Powell, Allison B Carroll, Sheh-Li Chen, Daniel Crona, Lee Ann Jones
Journal: Blood
Blood (2024) 144 (Supplement 1): 1237.
https://doi.org/10.1182/blood-2024-210540
Published: 2024
Journal Articles

Older Adults with Acute Myeloid Leukemia (AML) Experience Improvement in Health-Related Quality of Life (HRQoL) Scores with Intensive Therapy: Prospective Study from ECOG-ACRIN (EA) E2906 Phase 3 Trial

Free
James M. Foran, Li Chen, Selina M Luger, Zhuoxin Sun, Heidi Klepin, David F. Claxton, Hillard M. Lazarus, Jacob M. Rowe, Jessica K. Altman, Aref Al-Kali, Hong Zheng, Keith W Pratz, Edward R. Broun, Bayard L Powell, Kristen M. O'Dwyer, Yishai Ofran, John E. Godwin, Mark R. Litzow, Martin S. Tallman, Lynne Wagner
Journal: Blood
Blood (2023) 142 (Supplement 1): 594.
https://doi.org/10.1182/blood-2023-189734
Published: 2023
Journal Articles

Recommendations on Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia Treated with Combination of All- Trans Retinoic Acid and Arsenic Trioxide

Free
Li Chen, Hongming Zhu, Fangyi Dong, Yan Li, Qifa Liu, Yu Hu, Yicheng Zhang, Jie Jin, Jianda Hu, Ting Liu, Depei Wu, Jieping Chen, Yongrong Lai, Jianxiang Wang, Juan Li, Jianyong Li, Xin Du, Xin Wang, Mingzhen Yang, Jinsong Yan, Guifang Ouyang, Li Liu, Ming Hou, Xiaojun Huang, Wen Jin, Yongmei Zhu, Jian Li, Kankan Wang, Zhu Chen, Sai-Juan Chen, Junmin Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 2946.
https://doi.org/10.1182/blood-2023-184433
Published: 2023
Journal Articles

Real-World Experience of Ropeginterferon-Alfa Treatment of PV and ET - Two Centers Experience

Free
Tsewang Tashi, Brandi N. Reeves, Soo Jin Kim, Hyewon Jeong, Sheh-Li Chen, Brynn Parsegov, Josef T. Prchal
Journal: Blood
Blood (2023) 142 (Supplement 1): 6397.
https://doi.org/10.1182/blood-2023-191268
Published: 2023
Journal Articles

Ropegiterferon Alfa-2b-Njft for Treatment Myeloproliferative Neoplasms: A Single Institution Experience

Free
Callie Berkowitz, Sheh-Li Chen, Brandi Reeves
Journal: Blood
Blood (2022) 140 (Supplement 1): 12254–12255.
https://doi.org/10.1182/blood-2022-164733
Published: 2022