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Journal Articles

Comprehensive Clinical and Molecular Characterization Reveals Rara As the Most Frequent Torque Teno Mini Virus Insertion Site and Defines a Distinct Ttmv::Rara Driven APL-like Leukemia Subtype

Shu Sun, Yongjing Liu, Qing-Yu Xu, Xiaosu Zhou, Lijun Wen, Li Chen, Jiaqi Chen, Huili Wang, Xue Chen, Jiacheng Lou, Huyong Zheng, Yangyang Xie, Linya Wang, Futian Ma, Lihua Yang, Xianjing Wang, Wen Gao, Yin Wu, Leping Zhang, Shuhong Shen, Suning Chen, Kankan Wang, Hongxing Liu, Jinyan Huang, Hong-Hu Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1547.
https://doi.org/10.1182/blood-2024-202323
Published: 2024
Journal Articles

The Evolution of Treatments and Outcomes for Real-World Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Chinese National Medical Center: Over 10 Years of Experience with 370 Patients

Ran An, Wen Jin, Xiangqin Weng, Kankan Wang, Sujiang Zhang, Li Chen, Jianqing Mi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6790.
https://doi.org/10.1182/blood-2024-207401
Published: 2024
Journal Articles

Super-Enhancer-Associated Long Noncoding RNA Lnc-SPI1U Participates in PU.1 Feedback Regulation By Interacting with HNRNPH1 and Hnrnpf

Xuefei Ma, Weifen Sun, Yilu Li, Yun Tan, Xuefeng Wang, Kankan Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1356.
https://doi.org/10.1182/blood-2024-194099
Published: 2024
Journal Articles

Phase Separation of PML/RARα Microspeckles Governs Transcriptional Dysregulation through Genomic Rewiring of BRD4 in Acute Promyelocytic Leukemia

Yi Zhang, Kankan Wang, Jiacheng Lou, Yabin Liu, Peng Jin, Yun Tan, Huan Song, Wen Jin, Fangyi Dong, Shishuang Wu, Hai Fang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1367.
https://doi.org/10.1182/blood-2023-180510
Published: 2023
Journal Articles

T-Cell Receptor-Engineered T Cells Targeting FLT3-D835 Mutation-Derived Neoantigens in Acute Myeloid Leukemia

Weijun Zhou, Jinyi Yu, Fuyu Li, Kankan Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2072.
https://doi.org/10.1182/blood-2023-184708
Published: 2023
Journal Articles

Recommendations on Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia Treated with Combination of All- Trans Retinoic Acid and Arsenic Trioxide

Li Chen, Hongming Zhu, Fangyi Dong, Yan Li, Qifa Liu, Yu Hu, Yicheng Zhang, Jie Jin, Jianda Hu, Ting Liu, Depei Wu, Jieping Chen, Yongrong Lai, Jianxiang Wang, Juan Li, Jianyong Li, Xin Du, Xin Wang, Mingzhen Yang, Jinsong Yan, Guifang Ouyang, Li Liu, Ming Hou, Xiaojun Huang, Wen Jin, Yongmei Zhu, Jian Li, Kankan Wang, Zhu Chen, Sai-Juan Chen, Junmin Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 2946.
https://doi.org/10.1182/blood-2023-184433
Published: 2023
Journal Articles

Recurrent noncoding somatic and germline WT1 variants converge to disrupt MYB binding in acute promyelocytic leukemia

Huan Song, Yabin Liu, Yun Tan, Yi Zhang, Wen Jin, Li Chen, Shishuang Wu, Jinsong Yan, Junmin Li, Zhu Chen, Saijuan Chen, Kankan Wang
Journal: Blood
Blood (2022) 140 (10): 1132–1144.
https://doi.org/10.1182/blood.2021014945
Published: 2022
Includes: Supplemental data
Journal Articles

A PML/RARα direct target atlas redefines transcriptional deregulation in acute promyelocytic leukemia

Yun Tan, Xiaoling Wang, Huan Song, Yi Zhang, Rongsheng Zhang, Shufen Li, Wen Jin, Saijuan Chen, Hai Fang, Zhu Chen, Kankan Wang
Journal: Blood
Blood (2021) 137 (11): 1503–1516.
https://doi.org/10.1182/blood.2020005698
Published: 2021
Includes: Supplemental data
Journal Articles

Long Noncoding RNA Profiling Reveals an Abundant Crnde That Inhibits Granulocytic Differentiation in APL

Xuefei Ma, MS, Wen Jin, PhD, Ming Zhao, MS, Wei Zhang, MD, Jingming Li, BS, Kankan Wang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3799.
https://doi.org/10.1182/blood.V130.Suppl_1.3799.3799
Published: 2017
Journal Articles

Mutation Profiling and Associated Clinical Features in Chinese Cytogenetically Normal Acute Myeloid Leukemia Patients

Shu Wang, Yun-Xiang Zhang, Ting Huang, Kankan Wang, PhD, Jun-Min LI, MD PhD, Jin-yan Huang, PhD, Bing Chen, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5102.
https://doi.org/10.1182/blood.V130.Suppl_1.5102.5102
Published: 2017
Journal Articles

Influence of Body Mass Index on Incidence and Prognosis of Acute Myeloid Leukemia and Acute Promyelocytic Leukemia: A Systematic Review and Meta-Analysis

Shufen Li, Li Chen, Kankan Wang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5023.
https://doi.org/10.1182/blood.V130.Suppl_1.5023.5023
Published: 2017
Journal Articles

Coordinated Repression of Cyclin-Dependent Kinase Inhibitors By PML/RARa in Acute Promyelocytic Leukemia

Yun Tan, Wen Jin, Xiaoling Wang, Kankan Wang
Journal: Blood
Blood (2016) 128 (22): 1517.
https://doi.org/10.1182/blood.V128.22.1517.1517
Published: 2016
Journal Articles

Genome-wide studies identify a novel interplay between AML1 and AML1/ETO in t(8;21) acute myeloid leukemia

Yizhen Li, Huanwei Wang, Xiaoling Wang, Wen Jin, Yun Tan, Hai Fang, Saijuan Chen, Zhu Chen, Kankan Wang
Journal: Blood
Blood (2016) 127 (2): 233–242.
https://doi.org/10.1182/blood-2015-03-626671
Published: 2016
Includes: Supplemental data
Journal Articles

IRF1 Is Crucial for ATRA-Induced Differentiation By Regulating Its Multiple Functional Targets

Wen Jin, Huanwei Wang, Dong Shi, Kankan Wang
Journal: Blood
Blood (2014) 124 (21): 2220.
https://doi.org/10.1182/blood.V124.21.2220.2220
Published: 2014
Journal Articles

Transcriptional Repression Of CDKN2D by PML/RARα Contributes To The Altered Proliferation and Differentiation Block Of Acute Promyelocytic Leukemia Cells

Xiaohong Jia, Yun Tan, Yewei Wang, Xuehua Zhu, Xianwen Yang, Wen Jin, Ji Zhang, Kankan Wang
Journal: Blood
Blood (2013) 122 (21): 3743.
https://doi.org/10.1182/blood.V122.21.3743.3743
Published: 2013
Journal Articles

AML1-ETO Represses Multiple Transcription Factor Induced CTSG Activation by Reducing H3 Acetylation

Yun Tan, Wen Jin, Kang Wu, Kankan Wang
Journal: Blood
Blood (2013) 122 (21): 3750.
https://doi.org/10.1182/blood.V122.21.3750.3750
Published: 2013
Journal Articles

PML/RARa Represses Transactivation of PSMB10 Via a PU.1-Dependent Manner In Acute Promyelocytic Leukemia

Xianwen Yang, Ping Wang, Xujie Zhao, Huahua Zhu, Sai-Juan Chen, Ji Zhang, Kankan Wang
Journal: Blood
Blood (2010) 116 (21): 3866.
https://doi.org/10.1182/blood.V116.21.3866.3866
Published: 2010
Journal Articles

Coordination of Fenretinide-Induced Apoptosis by Stress-Responsive Regulators in Leukemia Cells

Kankan Wang, Hai Fang, Da-Kai Xiao, Xue-Hua Zhu, Miao- Miao He, Xiao-Ling Pan, Sai-Juan Chen, PhD, Ji Zhang
Journal: Blood
Blood (2008) 112 (11): 4730.
https://doi.org/10.1182/blood.V112.11.4730.4730
Published: 2008
Journal Articles

Expression of Tissue Factor Is up-Regulated in U937/PR9 Cells by the PML/RARα Fusion Protein through Its Interaction with the Regulatory Region of Tissue Factor Promoter.

Jingsong Yan, Hongchen Liu, Xiaoyu Su, Ping Wang, Zhen Ruan, Kankan Wang, Zhu Chen, Saijuan Chen, Xiaodong Xi
Journal: Blood
Blood (2008) 112 (11): 2033.
https://doi.org/10.1182/blood.V112.11.2033.2033
Published: 2008
Journal Articles

A Probabilistic Integrated Gene Network Model of Multiple Hematopoietic Lineage Specification

Hai Fang, Kankan Wang, Ji Zhang
Journal: Blood
Blood (2008) 112 (11): 4767.
https://doi.org/10.1182/blood.V112.11.4767.4767
Published: 2008