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Journal Articles

Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repression

Tianyi Zhang, Yi-Fang Wang, Alex Montoya, Ilinca Patrascan, Nehir Nebioglu, Husayn A Pallikonda, Radina Georgieva, James WD King, Holger B Kramer, Pavel V Shliaha, David S. Rueda, Matthias Merkenschlager

Blood blood.2024024787.

https://doi.org/10.1182/blood.2024024787

Published: 2024

Includes: Supplemental data

Journal Articles

Critical role of tripartite fusion and LBD truncation in certain RARA - and all RARG -related atypical APL

Blood (2024) 144 (14): 1471–1485.

https://doi.org/10.1182/blood.2024023883

Published: 2024

Includes: Supplemental data

Journal Articles

Deciphering the Structural Variants in B Cell Acute Lymphoblastic Leukemia By Optical Genome Mapping

Ming Liu, Yang Zhang, Xue Chen, Fang Wang, Jiaqi Chen, Panxiang Cao, Xiaoli Ma, Jiancheng Fang, Xiaosu Zhou, Tong Wang, Hongxing Liu

Blood (2023) 142 (Supplement 1): 1610.

https://doi.org/10.1182/blood-2023-189032

Published: 2023

Journal Articles

Partner Gene Associated Trinary Fusion and Orchestration of Multiple Molecular Events in Acute Promyelocytic Leukemia with Variant Rara Fusion Genes

Blood (2023) 142 (Supplement 1): 1414.

https://doi.org/10.1182/blood-2023-187869

Published: 2023

Journal Articles

Discovery of Novel, First-in-Class Allosteric Modulators of MALT1 Scaffolding Function with Differentiated Pharmacology for NFκB-Driven Malignancies

Yi Yao, Yingzhi Bi, Huadong Sun, Kevin Ling, Huili Xia, Jun Kuai, Patrick DePaolo, Virginie Lafont, David Diller, Ara Aslanian, Samira Jaeger, Joe Wahle, Wei Liu, Ken Carson, Timothy Reilly, Gerry Harriman, Fang Wang

Blood (2023) 142 (Supplement 1): 52.

https://doi.org/10.1182/blood-2023-172899

Published: 2023

Journal Articles

Advances in Acute Myeloid Leukemia Classification: A Comparative Analysis of Who-HAEM4R, Who-HAEM5, and International Consensus Classification

Xue Chen, Lili Yuan, Yang Zhang, Fang Wang, Xiaoli Ma, Jiancheng Fang, Panxiang Cao, Yijun Liu, Zhixiu Liu, Ming Liu, Jiaqi Chen, Xiaosu Zhou, Mingyue Liu, David Jin, Peihua Lu, Hongxing Liu

Blood (2023) 142 (Supplement 1): 1566.

https://doi.org/10.1182/blood-2023-187915

Published: 2023

Journal Articles

The Ingenious Multiple Efficacies of the Integrated Gene Fragment of Torque Teno Mini Virus in Orchestrating Promyelocytic Leukemogenesis Via Hijacking Rara

Blood (2023) 142 (Supplement 1): 1576.

https://doi.org/10.1182/blood-2023-185426

Published: 2023

Journal Articles

Trinary Fusion with Ligand Binding Domain Castration Is Crucial in Rarg -Driven APL and Render Unresponsive to ATRA Via Allosteric Disability Mechanism

Blood (2023) 142 (Supplement 1): 2949.

https://doi.org/10.1182/blood-2023-185483

Published: 2023

Journal Articles

Extensive CXCR4-MAPK Signaling Activation in the Novel B Cell Acute Lymphoblastic Subtype of CDX2/Ubtf

Panxiang Cao, Mingyu Wang, Guangsi Zhang, Fang Wang, Yang Zhang, Xue Chen, Xiaoli Ma, Ming Liu, Hongxing Liu

Blood (2023) 142 (Supplement 1): 5722.

https://doi.org/10.1182/blood-2023-188306

Published: 2023

Journal Articles

JAK2 Kinase Fusion and Myeloid Involvement in Acute Lymphoblastic Leukemia

Tong Wang, Jingbo Ni, Xue Chen, Panxiang Cao, Jinan Tan, Hongwei Zhang, Jiangcheng Fang, Xinying Wei, Jiaqi Chen, Xiaoli Ma, Yang Zhang, Fang Wang, Yan Zhang, Yan Dai, Hongxing Liu

Blood (2023) 142 (Supplement 1): 4348.

https://doi.org/10.1182/blood-2023-181682

Published: 2023

Journal Articles

Deciphering the Structural Variants in Acute Myeloid Leukemia and Myelodysplastic Neoplasms By Optical Genome Mapping

Ming Liu, Yang Zhang, Xue Chen, Fang Wang, Jiaqi Chen, Panxiang Cao, Xiaoli Ma, Jiancheng Fang, Xiaosu Zhou, Tong Wang, Hongxing Liu

Blood (2023) 142 (Supplement 1): 6018.

https://doi.org/10.1182/blood-2023-189366

Published: 2023

Journal Articles

Optimization of Intravenous Odronextamab Step-up Regimen for Reducing the Risk of High-Grade Cytokine Release Syndrome

Min Zhu, Jurriaan Brouwer-Visser, Srikanth R. Ambati, Hesham Mohamed, Vladimir Jankovic, Fang Wang, Hong Yan, Jingxian Cai, Carolina Leite De Oliveira, Melanie Ufkin, John D. Davis, Aafia Chaudhry, Masood Khaksar Toroghi

Blood (2022) 140 (Supplement 1): 11560–11561.

https://doi.org/10.1182/blood-2022-158415

Published: 2022

Journal Articles

A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation

Fengjiao Wang, Jiahuan He, Siqi Liu, Ai Gao, Liu Yang, Guohuan Sun, Wanqiu Ding, Chuan-Yun Li, Fanglin Gou, Manman He, Fang Wang, Xiaoshuang Wang, Xiangnan Zhao, Ping Zhu, Sha Hao, Yanni Ma, Hui Cheng, Jia Yu, Tao Cheng

Blood (2021) 138 (20): 1939–1952.

https://doi.org/10.1182/blood.2021011314

Published: 2021

Includes: Supplemental data

Journal Articles

Relapse Analysis and Resistance Mutations of PML-Rara Fusion Gene in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Arsenic

Jiaqi Chen, Hongxing Liu, Fang Wang, Xue Chen, Yang Zhang, Panxiang Cao, Xiaoli Ma, Yu Li

Blood (2021) 138 (Supplement 1): 2243.

https://doi.org/10.1182/blood-2021-149404

Published: 2021

Journal Articles

Aberrant Dntt Expression, TdT-Aided Gene Length Mutations, and Prognosis Relevance in ATG/Alg Based Regimen Allo-HSCT in Acute Myeloid Leukemias

Xiaosu Zhou, Daijing Nie, Yang Zhang, Zhixiu Liu, Jianping Zhang, Yanli Zhao, Fang Wang, Jiancheng Fang, Panxiang Cao, Xue Chen, Xiaoli Ma, Jiaqi Chen, Qisheng Wu, Peihua Lu, Hongxing Liu

Blood (2021) 138 (Supplement 1): 2367.

https://doi.org/10.1182/blood-2021-150355

Published: 2021

Journal Articles

Clinical and Molecular Characteristics of TCF3-Hlf Gene Fusion-Positive B-Cell Precursor Acute Lymphoblastic Leukemia: A Series of 24 Cases from a Large Cohort of Leukemia Patients

Xue Chen, Fang Wang, Yang Zhang, Xiaoli Ma, Lili Yuan, Jiancheng Fang, Cao Panxiang, Jiaqi Chen, Xiaosu Zhou, Ming Liu, Mingyue Liu, Hongxing Liu

Blood (2021) 138 (Supplement 1): 2387.

https://doi.org/10.1182/blood-2021-154340

Published: 2021

Journal Articles

Transcriptome Based Classification Model and Co-Expression Networks Analysis Identify CXCR4alt Subtype and Blnkaf in B-Cell Precursor Acute Lymphoblastic Leukemia

Panxiang Cao, Mingyu Wang, Guangsi Zhang, Fang Wang, Xue Chen, Yang Zhang, Daijing Nie, Xiaoli Ma, Ming Liu, Hongxing Liu

Blood (2021) 138 (Supplement 1): 1312.

https://doi.org/10.1182/blood-2021-152204

Published: 2021

Journal Articles

Transcriptional Profile Investigation Identified Aberrant CD34 Isoforms and Apela As a Hub Gene in IGH-DUX4 Subtype B-Cell Precursor Acute Lymphoblastic Leukemia

Guangsi Zhang, Panxiang Cao, Fang Wang, Xue Chen, Yang Zhang, Mingyu Wang, Daijing Nie, Xiaoli Ma, Ming Liu, Hongxing Liu

Blood (2021) 138 (Supplement 1): 4473.

https://doi.org/10.1182/blood-2021-152139

Published: 2021

Journal Articles

Fusion Gene Map of Acute Myeloid Leukemia Revealed By Transcriptome Sequencing of a Consecutive Cohort of 400 Cases in a Single Center

Xue Chen, MD, Fang Wang, MD, Panxiang Cao, MS, Xiaoli Ma, MD, Lili Yuan, MD, Yang Zhang, MD, Daijing Nie, MD, Jiaqi Chen, MD, Xiaosu Zhou, Ming Liu, MD, Zhixiu Liu, MD, Mingyue Liu, Hongxing Liu, MD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-141144

Published: 2020

Journal Articles

Classification and Quantification of Oncogenic Ikaros Isoforms in B Cell Precursor Acute Lymphoblastic Leukemia By RNA-Seq

Guangsi Zhang, Cao Panxiang, Fang Wang, MD, Xue Chen, MD, Yang Zhang, MD, Mingyu Wang, Xiaoli Ma, MD, Jiaqi Chen, MD, Daijing Nie, Hongxing Liu

Blood (2020) 136 (Supplement 1): 2–3.

https://doi.org/10.1182/blood-2020-140285

Published: 2020

NARROW

Conserved helical motifs in the IKZF1 disordered region mediate NuRD interaction and transcriptional repression

Critical role of tripartite fusion and LBD truncation in certain RARA - and all RARG -related atypical APL

Deciphering the Structural Variants in B Cell Acute Lymphoblastic Leukemia By Optical Genome Mapping

Partner Gene Associated Trinary Fusion and Orchestration of Multiple Molecular Events in Acute Promyelocytic Leukemia with Variant Rara Fusion Genes

Discovery of Novel, First-in-Class Allosteric Modulators of MALT1 Scaffolding Function with Differentiated Pharmacology for NFκB-Driven Malignancies

Advances in Acute Myeloid Leukemia Classification: A Comparative Analysis of Who-HAEM4R, Who-HAEM5, and International Consensus Classification

The Ingenious Multiple Efficacies of the Integrated Gene Fragment of Torque Teno Mini Virus in Orchestrating Promyelocytic Leukemogenesis Via Hijacking Rara

Trinary Fusion with Ligand Binding Domain Castration Is Crucial in Rarg -Driven APL and Render Unresponsive to ATRA Via Allosteric Disability Mechanism

Extensive CXCR4-MAPK Signaling Activation in the Novel B Cell Acute Lymphoblastic Subtype of CDX2/Ubtf

JAK2 Kinase Fusion and Myeloid Involvement in Acute Lymphoblastic Leukemia

Deciphering the Structural Variants in Acute Myeloid Leukemia and Myelodysplastic Neoplasms By Optical Genome Mapping

Optimization of Intravenous Odronextamab Step-up Regimen for Reducing the Risk of High-Grade Cytokine Release Syndrome

A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation

Relapse Analysis and Resistance Mutations of PML-Rara Fusion Gene in Acute Promyelocytic Leukemia Patients Treated with All-Trans Retinoic Acid and Arsenic

Aberrant Dntt Expression, TdT-Aided Gene Length Mutations, and Prognosis Relevance in ATG/Alg Based Regimen Allo-HSCT in Acute Myeloid Leukemias

Clinical and Molecular Characteristics of TCF3-Hlf Gene Fusion-Positive B-Cell Precursor Acute Lymphoblastic Leukemia: A Series of 24 Cases from a Large Cohort of Leukemia Patients

Transcriptome Based Classification Model and Co-Expression Networks Analysis Identify CXCR4alt Subtype and Blnkaf in B-Cell Precursor Acute Lymphoblastic Leukemia

Transcriptional Profile Investigation Identified Aberrant CD34 Isoforms and Apela As a Hub Gene in IGH-DUX4 Subtype B-Cell Precursor Acute Lymphoblastic Leukemia

Fusion Gene Map of Acute Myeloid Leukemia Revealed By Transcriptome Sequencing of a Consecutive Cohort of 400 Cases in a Single Center

Classification and Quantification of Oncogenic Ikaros Isoforms in B Cell Precursor Acute Lymphoblastic Leukemia By RNA-Seq

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American Society of Hematology

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American Society of Hematology

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