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Journal Articles

Comprehensive Translatomic Analysis of Multiple Myeloma Unveils Novel Insights into Disease Pathogenesis

Lirong Liu, Le Wu, Xinyu Li, Xiaoyun Jin, Xiaoya Chen, Guangjue Tang, Huixing Zhou, Yuan Jian, Wenming Chen, Guangzhong Yang, Yan Huang, Fang Wang, Jia Yu, Wen Gao, Dong Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 3260.
https://doi.org/10.1182/blood-2024-197870
Published: 2024
Journal Articles

Updated Safety and Efficacy Results of RM-001, Autologous HBG1/2 Promoter-Modified CD34+ Hematopoietic Stem and Progenitor Cells, in Treating Transfusion-Dependent β-Thalassemia

Rongrong Liu, Li Wang, Hui Xu, Jianpei Fang, Sixi Liu, Xiaolin Yin, Junbin Liang, Xinyu Li, Yue Li, Gaohui Yang, Yaoyun Li, Yali Zhou, Lei Shi, Yongrong Lai, Junjiu Huang, Xinhua Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4960.
https://doi.org/10.1182/blood-2024-206549
Published: 2024
Journal Articles

Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia

Yongwei Su, Xinyu Li, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Katie Hege, Yu Fukuda, John D. Schuetz, PhD, Joshua E. Allen, PhD, Martin Stogniew, Varun Vijay Prabhu, BPharm, MS, PhD, Jeffrey W. Taub, MD, Hai Lin, MD, Yubin Ge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3936.
https://doi.org/10.1182/blood-2018-99-116997
Published: 2018
Journal Articles

Inhibition of ATR Potentiates Acute Myeloid Leukemia Cells to the RNA Pol I Transcription Inhibitor CX-5461

Margaret Shatara, MD, Tingting Wang, Xinyu Li, Holly Edwards, BS, Jeffrey W. Taub, MD, Hai Lin, MD, Yubin Ge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5224.
https://doi.org/10.1182/blood-2018-99-113937
Published: 2018
Journal Articles

Targeting PI3K, mTOR, ERK, and Bcl-2 Signaling Network Shows Superior Antileukemic Activity Against AML

Yongwei Su, Xinyu Li, Jianyun Zhao, Jun Ma, Shuang Liu, Holly Edwards, Jeffrey W. Taub, MD, Hai Lin, Yubin Ge, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1255.
https://doi.org/10.1182/blood.V130.Suppl_1.1255.1255
Published: 2017
Journal Articles

ONC213, a Novel Second Generation Analog of ONC201, Shows Promising Anti-Leukemic Activity Against AML Cells In Vitro and In Vivo

Yongwei Su, Xinyu Li, Holly Edwards, Joshua E. Allen, PhD, Martin Stogniew, Varun Vijay Prabhu, BPharm, MS, PhD, Jeffrey W. Taub, MD, Hai Lin, Yubin Ge, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3822.
https://doi.org/10.1182/blood.V130.Suppl_1.3822.3822
Published: 2017
Journal Articles

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemic Pathogenesis

Andrew Volk, PhD, Kaiwei Liang, PhD, Jianyun Zhao, Xinyu Li, Marinka Bulic, Stacy Marshall, Jeffrey W. Taub, MD, Yubin Ge, PhD, Sebastien Malinge, PhD, Elizabeth Bartom, PhD, Ali Shilatifard, PhD, John D. Crispino, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 245.
https://doi.org/10.1182/blood.V130.Suppl_1.245.245
Published: 2017
Journal Articles

Klotho/IGF-1R Regulates Tumor Growth and Predicts Prognosis in Diffuse Large B-Cell Lymphoma

Xiangxiang Zhou, MD, Ying Li, MD, Xinyu Li, MD, Lingyun Geng, MD, Ya Zhang, MD, Yujie Jiang, PhD, Xin Wang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2924.
https://doi.org/10.1182/blood.V128.22.2924.2924
Published: 2016
Journal Articles

Combination of Venetoclax and CUDC-907 Shows Superior Antileukemic Activity Against Acute Myeloid Leukemia Ex Vivo

Xinyu Li, Jun Ma, Yongwei Su, Jianyun Zhao, Holly Edwards, Yue Wang, Jay Yang, MD, Jeffrey W Taub, MD, Hai Lin, Yubin Ge, PhD
Journal: Blood
Blood (2016) 128 (22): 1571.
https://doi.org/10.1182/blood.V128.22.1571.1571
Published: 2016
Journal Articles

5-Aza-2-Deoxycytidine Regulates Wnt Beta-Catenin Pathway in B Cell Lymphoma

Xinyu Li, MD, Lingyu Geng, MD, Xiangxiang Zhou, MD, Kang Lu, PhD, Peipei Li, PhD, Xin Wang, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4810.
https://doi.org/10.1182/blood.V126.23.4810.4810
Published: 2015
Journal Articles

Insulin-like Growth Factor-1 Receptor (IGF-1R) As a Potential Therapeutic Target in Diffuse Large B-Cell Lymphoma

Xiangxiang Zhou, MD, Lingyun Geng, MD, Xinyu Li, MD, Peipei Li, PhD, Kang Lu, PhD, Xin Wang, MDPhD
Journal: Blood
Blood (2015) 126 (23): 4828.
https://doi.org/10.1182/blood.V126.23.4828.4828
Published: 2015
Journal Articles

Gli1 Inhibitor GANT61 Exhibits Antitumor Efficacy in T-Cell Lymphoma Cells through Down-Regulation of p-STAT3 and SOCS3 Pathways

Lingyun Geng, MD, Xiangxiang Zhou, MD, Xinyu Li, MD, Kang Lu, PhD, Peipei Li, PhD, Xin Wang, MDPhD
Journal: Blood
Blood (2015) 126 (23): 1287.
https://doi.org/10.1182/blood.V126.23.1287.1287
Published: 2015
Journal Articles

Inhibition of STAT3 Reverses the Resistance to Histone Deacetylase Inhibitors Induced By Interleukin-6 in Chronic Lymphocytic Leukemia Cells

Kang Lu, MM, Xin Wang, MD PhD, Xiaosheng Fang, PhD, Lili Feng, PhD, Na Chen, PhD, Peipei Li, PhD, Xinyu Li, MM, Lingyun Geng, BD
Journal: Blood
Blood (2014) 124 (21): 3632.
https://doi.org/10.1182/blood.V124.21.3632.3632
Published: 2014
Journal Articles

AML Cells Utilize TNF-Driven JNK Signaling As a Critical NF-κB-Independent Survival Signal

Andrew Volk, Jing Li, PhD, Junping Xin, PhD, Dewen You, PhD, Jun Zhang, PhD, Peter Breslin, PhD, Zejuan Li, MD, PhD, Wei Wei, Rachel Schmidt, Xinyu Li, MD, Zhou Zhang, PhD, Paul C Kuo, MD, Sucha Nand, MD, Jianke Zhang, PhD, Jianjun Chen, PhD, Jiwang Zhang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2890.
https://doi.org/10.1182/blood.V122.21.2890.2890
Published: 2013