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Journal Articles

Updated Safety and Efficacy Results of RM-001, Autologous HBG1/2 Promoter-Modified CD34+ Hematopoietic Stem and Progenitor Cells, in Treating Transfusion-Dependent β-Thalassemia

Rongrong Liu, Li Wang, Hui Xu, Jianpei Fang, Sixi Liu, Xiaolin Yin, Junbin Liang, Xinyu Li, Yue Li, Gaohui Yang, Yaoyun Li, Yali Zhou, Lei Shi, Yongrong Lai, Junjiu Huang, Xinhua Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4960.
https://doi.org/10.1182/blood-2024-206549
Published: 2024
Journal Articles

First-in-Human Study of Autologous HBA2-Edited CD34+ Hematopoietic Stem and Progenitor Cells in Alpha-Thalassemia with Constant Spring Mutation

Li Wang, Hui Xu, Junbin Liang, Yaoyun Li, Lin Cheng, Ying Luo, Liancheng Huang, Lei Shi, Lihong Zeng, Rongrong Luo, Bin Xiao, Meiping Liu, Liping Huang, Zhendong Xiao, Xinhua Zhang, Junjiu Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4959.
https://doi.org/10.1182/blood-2024-206807
Published: 2024
Journal Articles

Safety and Efficacy of RM-001 (Autologous HBG1/2 Promoter-modified CD34+ Hematopoietic Stem and Progenitor Cells) in Patients with Transfusion-Dependent β-Thalassemia

Rongrong Liu, Li Wang, Hui Xu, Xiaolin Yin, Junbin Liang, Wenqiang Xie, Gaohui Yang, Yaoyun Li, Yali Zhou, Lei Shi, Bin Xiao, Lingling Shi, Zeyan Shi, Xuemei Zhou, Xiangmin Xu, Jianpei Fang, Yongrong Lai, Junjiu Huang, Xinhua Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4994.
https://doi.org/10.1182/blood-2023-181453
Published: 2023
Journal Articles

A natural DNMT1 mutation elevates the fetal hemoglobin level via epigenetic derepression of the γ-globin gene in β-thalassemia

Brief Report
Yi Gong, Xinhua Zhang, Qianqian Zhang, Yanxia Zhang, Yuhua Ye, Wenxia Yu, Congwen Shao, Tizhen Yan, Jin Huang, Jianmei Zhong, Li Wang, Yaoyun Li, Liren Wang, Xiangmin Xu
Journal: Blood
Blood (2021) 137 (12): 1652–1657.
https://doi.org/10.1182/blood.2020006425
Published: 2021
Includes: Supplemental data