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Journal Articles

Efficacy and safety of rocbrutinib, a highly selective 4th-generation Bruton's tyrosine kinase inhibitor, in relapsed/refractory Mantle Cell Lymphoma (R/R MCL): Updated results from the phase 1 study

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Zhengming Jin, Ming Jiang, Xiuhua Sun, Lei Zhang, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, MIN Zhou, Hongmei Jing, Wei Yang, Hui Zhou, Jun Ma, Zhigang Peng, Wei Xu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 3587.
https://doi.org/10.1182/blood-2025-3587
Published: 2025
Journal Articles

Hetrombopag for the treatment of chemotherapy-induced thrombocytopenia in advanced solid tumors: A multicenter, randomized, double-blind, placebo-controlled phase III trial

Free
ShuKui Qin, Yanqiao Zhang, Hongli Li, Yong Mao, Wenhui Yang, Zhong Xie, Yanyan Liu, Lixin Wan, Yanjun Zhang, Xizhi Zhang, Xinghua Han, Lizhu Lin, Jun Yao, Yong Li, Yun Wu, Lin Liu, Mingjun Zhang, Guixiang Weng, Junyan Yu, Tao Si, Li Zhang, Zhenyang Liu, Guoping Zhang, Yong Li, Jin Xia, Xiaoli Liao, Qingshan Li, Jin Lu, Tienan Yi, Na Li, Zhitu Zhu, Xiaoyan Lin, Kaijian Lei, Jie Ma, Donglu Zhao, Junye Xiong, Runzi Li, Xiang Lin, Qian Tang, Jun Ma
Journal: Blood
Blood (2025) 146 (Supplement 1): 1256.
https://doi.org/10.1182/blood-2025-1256
Published: 2025
Journal Articles

Efficacy and safety of rocbrutinib, a highly selective 4th-generation BTK inhibitor, in Chinese patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Zhengming Jin, Ming Jiang, Xiuhua Sun, Lei Zhang, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, MIN Zhou, Hongmei Jing, Wei Yang, Hui Zhou, Jun Ma, Zhigang Peng, Wei Xu, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 3896.
https://doi.org/10.1182/blood-2025-3896
Published: 2025
Journal Articles

Efficacy and safety of mitoxantrone hydrochloride liposome in peripheral T-cell lymphoma: A multicenter, non-interventional, ambispective cohort real-world study

Free
Donglu Zhao, Huiqiang Huang, Zhiming Li, Lihong Liu, Quande Lin, Jun Fang, Kaiyang Ding, Jie Jin, Yanhong Tong, Dengju Li, Zengjun Li, Liping Su, Liang Wang, Wenbin Qian, Xiuhua Sun, Xiaobo Wang, Pengcheng He, Wei Yang, Jinhai Ren, Liling Zhang, Zunmin Zhu, Lugui Qiu, Dehui Zou, Wei LIU, Hui Zhou, Dongfeng Luo, Xiaojing Yan, Zhenqian Huang, Lintao Bi, Rong FU, Yunhong Huang, Aichun Liu, Xi Zhang, Yao Liu, Hao Zhang, Guangxun Gao, Liangquan Geng, Jingbo Wang, Jia Li, Yi Wang, Liqun Zou, Ming Jiang, Jian Ge, Xiu Li Sun, Yanli Yang, Hongmei Jing, Kai Hu, Zhimin Yan, Shuangnian Xu, Xiangxiang Zhou, Ganggang Wang, Zhilin Gao, Li Liang, Hongfeng Ge, Qingshan Li, Zhixue Zhang, Wuping Li, Xiaojing Xing, Fengzi Wang, Dongping Huang, Jun Qian, Hua Fan, Chanjuan Shen, Jun Ma
Journal: Blood
Blood (2025) 146 (Supplement 1): 1878.
https://doi.org/10.1182/blood-2025-1878
Published: 2025
Journal Articles

Safety and Efficacy of Rocbrutinib in Patients with Relapsed/Refractory Marginal Zone Lymphoma

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1635.
https://doi.org/10.1182/blood-2024-194572
Published: 2024
Journal Articles

Rocbrutinib, a New-Generation BTK Inhibitor, Demonstrates Safety and Efficacy in Relapsed/Refractory Non-GCB Diffuse Large B Cell Lymphoma

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3119.
https://doi.org/10.1182/blood-2024-194561
Published: 2024
Journal Articles

BTK Degradation As a Novel Therapeutic Strategy in Relapsed CNS Lymphoma: Proof of Concept Studies in Intracranial Patient-Derived, Rodent Models

Free
Jun Ma, Michael P Randall, Ming Lu, Lingjing Chen, Huimin Geng, Aishwarya Kumar, Saloni Malla, Mark Noviski, Ryan Rountree, James L. Rubenstein
Journal: Blood
Blood (2024) 144 (Supplement 1): 2988.
https://doi.org/10.1182/blood-2024-211266
Published: 2024
Journal Articles

Fatty Acid Metabolism Shapes Immune Function and PI3K Inhibitor Sensitivity in Chronic Lymphocytic Leukemia

Free
Yang Zhang, Jun Ma, Hua Wang, Pan Gao, Xin Wang, Ya Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6763.
https://doi.org/10.1182/blood-2024-208098
Published: 2024
Journal Articles

Mitoxantrone Hydrochloride Liposome Combined with Cytarabine As Induction Therapy for Patients with Newly Diagnosed Secondary Acute Myeloid Leukemia

Free
Yun Wang, Weida Wang, Jingbo Xu, Ji Ma, Hua Wang, Bingyi Wu, Yuanbin Song, Weiran Lv, Lezong Chen, Jun Ma, Tiejun Gong, Yang Liang
Journal: Blood
Blood (2024) 144 (Supplement 1): 6074.
https://doi.org/10.1182/blood-2024-209055
Published: 2024
Journal Articles

Anti-Btla Antibody Tifcemalimab As a Single Agent or in Combination with Toripalimab in Relapsed/Refractory Lymphomas

Free
Yuqin Song, JUN MA, Yan Xie, Huilai Zhang, Zhigang Peng, Yuerong Shuang, Fei Li, Yufu Li, Haiyan Yang, Xiuhua Sun, Liqun Zou, Yunhong Huang, Weili Zhao, Wenrong Huang, Hui Zhou, Mingying Liu, Weiwei Wang, Jing Xu, Yajie Wang, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4458.
https://doi.org/10.1182/blood-2023-181385
Published: 2023
Journal Articles

Mitoxantrone Hydrochloride Liposome Containing Regimen in Patients with Adult Acute Lymphoblastic Leukemia: A Multicenter, Retrospective, Real-World Study

Free
JUN MA, Tiejun Gong, Donglu Zhao, Xiaoyu Zhu, Xiaojing Yan, Junjie Ma, Yun Cai, HongXiang Wang, Mei Hong, Li Liu, Qiang Song, Xin Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5897.
https://doi.org/10.1182/blood-2023-187864
Published: 2023
Journal Articles

A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome

Free
Miao Miao, Depei WU, Shuangfeng Xie, Mei Hong, ChunKang Chang, Li Yu, Sujun Gao, Yan Li, Yuhua Li, Zunmin Zhu, Baolin Tang, Bingzong Li, Haiping Yang, Jishi Wang, Ling Qin, Rong Fu, Fei Li, Liangming Ma, Qifa Liu, Xin Du, Zhongxing Jiang, Zhenyu Li, Aijun Liu, Hongyan Tong, Jun Ma, Li Liu, Qingchi Liu, Yajing Xu, Hui Zhou, Yan Wang, Jianlin Chen, Ziru Niu, Mingxia Chen, Zhijian Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 4045–4046.
https://doi.org/10.1182/blood-2022-155901
Published: 2022
Journal Articles

Phase I Study of the Anti-Btla Antibody Tifcemalimab As a Single Agent or in Combination with Toripalimab in Relapsed/Refractory Lymphomas

Free
Jun Ma, Yuqin Song, Yan Xie, Hui-Lai Zhang, Yuerong Shuang, Zhigang Peng, Li Fei, Yunhong Huang, Weili Zhao, Wenrong Huang, Yali Pan, Mingying Liu, Feiwu Ran, Hui Feng, Sheng Yao, Patricia Keegan, Jianjun Zou, Jun Zhu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3716–3717.
https://doi.org/10.1182/blood-2022-157497
Published: 2022
Journal Articles

Disease Characteristics and Treatment Outcomes with HLX01: A Real-World Study in Patients with B-Cell Non-Hodgkin Lymphoma in China

Free
Jun Ma, Li Zhiming, Wei Xu, Yao Liu, Weili Zhao, Zhihua Yao, Kaiyang Ding, Yudan Wu, Hong Liu, Wenyu Li, Yirong Jiang, Li'e Lin, Zhigang Peng, Zhimin Zhai
Journal: Blood
Blood (2022) 140 (Supplement 1): 12130–12132.
https://doi.org/10.1182/blood-2022-166137
Published: 2022
Journal Articles

Nx-5948, a Selective Degrader of BTK with Activity in Preclinical Models of Hematologic and Brain Malignancies

Free
Daniel W Robbins, Mark Noviski, Ryan Rountree, May Tan, Nivetha Brathaban, Timothy Ingallinera, Dane E Karr, Aileen Kelly, Zef Konst, Jun Ma, Austin Tenn-McClellan, Jenny McKinnell, Luz Perez, Cristiana Guiducci, Gwenn Hansen, Arthur Sands
Journal: Blood
Blood (2021) 138 (Supplement 1): 2251.
https://doi.org/10.1182/blood-2021-147473
Published: 2021
Journal Articles

Prophylaxis of Neutropenia with Mecapegfilgrastim in Patients with Hematologic Malignancies

Free
Hui-qiang Huang, Zengjun Li, Gang Cheng, Gao Yan, Zhihua Yao, Guifang Zhang, Xiaoguang Wang, Zhengxiang Han, Yong Chen, Haijiao Yan, Weie Zheng, Jun Yan, Yulan Gu, Zhangxia Ren, Rusen Zhao, Ningling Zhang, Jun Ma
Journal: Blood
Blood (2021) 138 (Supplement 1): 4569.
https://doi.org/10.1182/blood-2021-149884
Published: 2021
Journal Articles

The Combination of CUDC-907 and Gilteritinib Shows Promising Antileukemic Activity in Vitro and In Vivo in Preclinical Models of FLT3-ITD AML

Free
Tristan Knight, MD, Xinan Qiao, BS, Jun Ma, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Kathryn White, Hai Lin, MD, Yue Wang, Jeffrey W. Taub, MD, Yubin Ge, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1262.
https://doi.org/10.1182/blood-2019-123793
Published: 2019
Journal Articles

Efficacy and Safety of Ibrutinib in Elderly Patients with Chronic Lymphocytic Leukemia

Free
Zhijian Cao, MD, Jun Ma, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5478.
https://doi.org/10.1182/blood-2019-126686
Published: 2019
Journal Articles

Efficacy and Safety of Low-Dose Decitabine in Low- or Intermediate 1-Risk MDS

Free
Zhijian Cao, MD, Jun Ma
Journal: Blood
Blood (2018) 132 (Supplement 1): 4377.
https://doi.org/10.1182/blood-2018-99-118683
Published: 2018
Journal Articles

Targeting PI3K, mTOR, ERK, and Bcl-2 Signaling Network Shows Superior Antileukemic Activity Against AML

Free
Yongwei Su, Xinyu Li, Jianyun Zhao, Jun Ma, Shuang Liu, Holly Edwards, Jeffrey W. Taub, MD, Hai Lin, Yubin Ge, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1255.
https://doi.org/10.1182/blood.V130.Suppl_1.1255.1255
Published: 2017