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Journal Articles

Toll-like Receptor 7/8 Pathway Is a Therapeutic Target in Primary CNS Lymphoma

Michael P Randall, Huimin Geng, Lingjing Chen, Aishwarya Ballapuram, Chitoh Yung, Ming Lu, Gregory Chin, Michael Mish, Jamie Bates, James L. Rubenstein

Blood (2024) 144 (Supplement 1): 978.

https://doi.org/10.1182/blood-2024-212194

Published: 2024

Journal Articles

BTK Degradation As a Novel Therapeutic Strategy in Relapsed CNS Lymphoma: Proof of Concept Studies in Intracranial Patient-Derived, Rodent Models

Jun Ma, Michael P Randall, Ming Lu, Lingjing Chen, Huimin Geng, Aishwarya Kumar, Saloni Malla, Mark Noviski, Ryan Rountree, James L. Rubenstein

Blood (2024) 144 (Supplement 1): 2988.

https://doi.org/10.1182/blood-2024-211266

Published: 2024

Journal Articles

Trial in Progress: A Phase I/II Study of Tafasitamab Plus Lenalidomide in Patients with Relapsed CNS Lymphoma

Michael P Randall, Andreas Rauschecker, Liam Gima-Lange, Jenai Wilmoth, Lingjing Chen, Ming Lu, Huimin Geng, Haifaa Abdulhaq, James L. Rubenstein

Blood (2023) 142 (Supplement 1): 3104.

https://doi.org/10.1182/blood-2023-190698

Published: 2023

Journal Articles

Regulation of CNS Lymphoma Progression By the Myeloid Microenvironment

Hua-Xin Gao, Eleanor Fraser, Mario Merlini, Huimin Geng, Lingjing Chen, Ming Lu, Yasmin Moshfegh, Joseph Cleveland, Jae Ryu, Jigyasa Sharma, David A. Solomon, Katerina Akassoglou, Clifford Lowell, James L. Rubenstein

Blood (2021) 138 (Supplement 1): 448.

https://doi.org/10.1182/blood-2021-153839

Published: 2021

Journal Articles

Application of Hyperpolarized 13C Magnetic Resonance Imaging to Detect Target Inhibition of NFkB Activation in Preclinical Patient-Derived Models of CNS Lymphoma

Huimin Geng, PhD, Brice Tiret, PhD, Hua-Xin Gao, PhD, Cigall Kadoch, PhD, Ming Lu, PhD, Lingjing Chen, PhD, Ilwoo Park, PhD, Gerd Melkus, PhD, Adam Elkhaled, PhD, John Kurhanewicz, PhD, Lisa Drew, PhD, Sebastien Degorce, PhD, Michele Mayo, PhD, Keith Dillman, PhD, Rana Anjum, PhD, Andrew Bloecher, PhD, Myriam Chaumeil, PhD, James Rubenstein, MD, PhD

Blood (2018) 132 (Supplement 1): 2840.

https://doi.org/10.1182/blood-2018-99-117625

Published: 2018

Journal Articles

Targeting NF-KB Activation in Novel Intracranial Models of CNS Lymphoma

Huimin Geng, PhD, Huaxin Gao, PhD, Cigall Kadoch, PhD, Ming Lu, Lingjing Chen, PhD, Rana Anjum, PhD, Lisa Drew, PhD, Sebastien Degorce, PhD, Keith Dillman, Michele Mayo, Shawn Anderson, Colin Collins, PhD, Clifford A. Lowell, MD PhD, James L. Rubenstein, MD, PhD

Blood (2016) 128 (22): 777.

https://doi.org/10.1182/blood.V128.22.777.777

Published: 2016

Journal Articles

Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy

Hua-Xin Gao, Ph.D., Shawn Anderson, Cigall Kadoch, Ph.D., Mekhala Maiti, Ph.D., Lingjing Chen, Ph.D., Dong-Han Yao, Gerd Melkus, Ph.D., Maria Wang, Ph.D., Yan Ren, Ph.D., Michael Breider, Ph.D., Carla Heise, PhD, Clifford A. Lowell, MD, PhD, Colin Collins, Ph.D., James L. Rubenstein, M.D., Ph.D.

Blood (2013) 122 (21): 374.

https://doi.org/10.1182/blood.V122.21.374.374

Published: 2013

Journal Articles

CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma

James L. Rubenstein, Valerie S. Wong, Cigall Kadoch, Hua-Xin Gao, Ramon Barajas, Lingjing Chen, S. Andrew Josephson, Brian Scott, Vanja Douglas, Mekhala Maiti, Lawrence D. Kaplan, Patrick A. Treseler, Soonmee Cha, Jimmy H. Hwang, Paola Cinque, Jason G. Cyster, Clifford Lowell

Blood (2013) 121 (23): 4740–4748.

https://doi.org/10.1182/blood-2013-01-476333

Published: 2013

Includes: Supplemental data

Journal Articles

Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma

James L. Rubenstein, Jing Li, Lingjing Chen, Ranjana Advani, Jan Drappatz, Elizabeth Gerstner, Tracy Batchelor, Hendrikus Krouwer, James Hwang, Glenna Auerback, Cigall Kadoch, Clifford Lowell, Pamela Munster, Soonmee Cha, Marc A. Shuman, Lloyd E. Damon

Blood (2013) 121 (5): 745–751.

https://doi.org/10.1182/blood-2012-07-440974

Published: 2013

Includes: Supplemental data

Journal Articles

Genomic and Molecular Properties of Relapsed CNS Lymphoma Using Novel Primary Meningeal Lymphoma Cell Lines and Intracranial Xenografts,

Hua-Xin Gao, Ph.D., Shawn Anderson, Lingjing Chen, Ph.D., Cigall Kadoch, BA, Byron C Hann, MD, PhD, Clifford Lowell, MD, PhD, Colin Collins, Ph.D., James L. Rubenstein, M.D., Ph.D.

Blood (2011) 118 (21): 3477.

https://doi.org/10.1182/blood.V118.21.3477.3477

Published: 2011

Journal Articles

Dynamic Changes in Macrophage Polarization Correlate with Progression and Response in CNS Lymphoma: Insights Into the Transcriptome of Lymphoma-Associated M2 Macrophages,

Cigall Kadoch, BA, Valerie Wong, Lingjing Chen, Ph.D., Anna Bet-Lachin, Ritu Roy, William Hyun, Caroline Behler, M.D., Clifford Lowell, MD, PhD, James L. Rubenstein, M.D., Ph.D.

Blood (2011) 118 (21): 3219.

https://doi.org/10.1182/blood.V118.21.3219.3219

Published: 2011

Journal Articles

Metabolic Profiling of CNS Lymphoma and Its Microenvironment

Anna Bet-Lachin, Frank Jiang, Lingjing Chen, Ph.D., Keyvan Keshari, Ph.D, David Wilson, M.D., Ph.D., John Kurhanewicz, Ph.D, James L. Rubenstein, M.D., Ph.D.

Blood (2011) 118 (21): 588.

https://doi.org/10.1182/blood.V118.21.588.588

Published: 2011

Journal Articles

Multicenter Phase I Trial of Intraventricular Immuno-Chemotherapy in Recurrent CNS Lymphoma

James L. Rubenstein, M.D., Ph.D., Lingjing Chen, Ph.D., Ranjana Advani, MD, Jan Drappatz, M.D., Elizabeth Gerstner, M.D., Tracy Batchelor, MD, Hendrikus Krouwer, M.D., Cigall Kadoch, BA, Pamela Munster, MD, Soonmee Cha, M.D., Marc A Shuman, MD, Lloyd E. Damon, MD

Blood (2011) 118 (21): 959.

https://doi.org/10.1182/blood.V118.21.959.959

Published: 2011

NARROW

Toll-like Receptor 7/8 Pathway Is a Therapeutic Target in Primary CNS Lymphoma

BTK Degradation As a Novel Therapeutic Strategy in Relapsed CNS Lymphoma: Proof of Concept Studies in Intracranial Patient-Derived, Rodent Models

Trial in Progress: A Phase I/II Study of Tafasitamab Plus Lenalidomide in Patients with Relapsed CNS Lymphoma

Regulation of CNS Lymphoma Progression By the Myeloid Microenvironment

Application of Hyperpolarized 13C Magnetic Resonance Imaging to Detect Target Inhibition of NFkB Activation in Preclinical Patient-Derived Models of CNS Lymphoma

Targeting NF-KB Activation in Novel Intracranial Models of CNS Lymphoma

Novel Intracranial Xenografts Of CNS Lymphoma Implicate a Role For Cereblon As a Mediator Of Lenalidomide Efficacy

CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma

Multicenter phase 1 trial of intraventricular immunochemotherapy in recurrent CNS lymphoma

Genomic and Molecular Properties of Relapsed CNS Lymphoma Using Novel Primary Meningeal Lymphoma Cell Lines and Intracranial Xenografts,

Dynamic Changes in Macrophage Polarization Correlate with Progression and Response in CNS Lymphoma: Insights Into the Transcriptome of Lymphoma-Associated M2 Macrophages,

Metabolic Profiling of CNS Lymphoma and Its Microenvironment

Multicenter Phase I Trial of Intraventricular Immuno-Chemotherapy in Recurrent CNS Lymphoma

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American Society of Hematology

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American Society of Hematology

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