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Journal Articles

Long-Term Sovleplenib Treatment of Adults with Primary Immune Thrombocytopenia in China

Yu Hu, Renchi Yang, Xiaofan Liu, Heng Mei, Hu Zhou, Shujie Wang, Ruibin Huang, Yi Wang, Xin Du, Jing Sun, Zeping Zhou, Zhenyu Yan, Wenming Chen, Wei Wang, Qingchi Liu, Qingshu Zeng, Yuping Gong, Jie Yin, Xuliang Shen, Baodong Ye, Yun Chen, Yajing Xu, Huiping Sun, Yunfeng Cheng, Zhuogang Liu, Chunling Wang, Guolin Yuan, Xiaohui Zhang, Xin Li, Peng Cheng, Xinhong Guo, Zhongxing Jiang, Feng'e Yang, Linhua Yang, Chengwei Luo Luo, Taiwu Xiao, Hongyan Yin, Xiaojun Guo, Xian Luo, Songhua Fan, Michael M. Shi, Weiguo Su
Journal: Blood
Blood (2024) 144 (Supplement 1): 2558.
https://doi.org/10.1182/blood-2024-204447
Published: 2024
Journal Articles

Post Hoc Analysis of Phase III Gecacitinib Clinical Trial Outcomes: Enhanced Understanding and Implications

Yi Zhang, Hu Zhou, Shanshan Suo, Junling Zhuang, Linhua Yang, Aili He, Qingchi Liu, Xin Du, Sujun Gao, Yarong Li, Yan Li, Yuqing Chen, Wen Wu, Huanling Zhu, Guangsheng He, Mei Hong, Qian Jiang, Zhongxing Jiang, Hongmei Jing, Jishi Wang, Na Xu, Lingling Yue, Cuiping Zheng, ZePing Zhou, Chenghao Jin, Xin Li, Lin Liu, Yajing Xu, Dengshu Wu, Feng Zhang, Jin Zhang, Zhijian Xiao, Jie Jin
Journal: Blood
Blood (2024) 144 (Supplement 1): 3165.
https://doi.org/10.1182/blood-2024-202790
Published: 2024
Journal Articles

Decoding the Immune Microenvironment of Primary Chronic Myelomonocytic Leukemia and Secondary Chronic Myelomonocytic Leukemia Due to DLBCL with CD19 CAR-T Failure By Single-Cell RNA-Seq

Xudong Li, Hong Huang, Binglei Zhang, Zhongxing Jiang, Yongping Song, Wenyi Lu, Bian Zhilei, Wei Li, Weijie Cao
Journal: Blood
Blood (2024) 144 (Supplement 1): 6695.
https://doi.org/10.1182/blood-2024-201202
Published: 2024
Journal Articles

The Impact of Anti-HLA Antibodies on the Prognosis of Allogeneic Hematopoietic Stem Cell Transplantation in Myelodysplastic Syndrome

Tiantian Xie, Runqing Lu, Weijie Cao, Bian Zhilei, Wei Li, Zhongxing Jiang, Yongping Song, Dengju Li, Rong Guo
Journal: Blood
Blood (2024) 144 (Supplement 1): 7419.
https://doi.org/10.1182/blood-2024-206974
Published: 2024
Journal Articles

Antithymocyte Globulin Enhances Myeloid-Derived Suppressor Cell Expansion and Function in Severe Aplastic Anemia

Peiyuan Dong, Yilin Liu, Zhongxing Jiang, Huimin Sun, Yanhong Zhao, Linjie Wu, Jiali Huo, Jing Zhang, Meili Ge, Fang Dong, Sha Hao, Tao Cheng
Journal: Blood
Blood (2024) 144 (Supplement 1): 4073.
https://doi.org/10.1182/blood-2024-202325
Published: 2024
Journal Articles

SLC25A21 Correlates with the Prognosis of Adult Acute Myeloid Leukemia through Inhibiting the Growth of Leukemia Cells Via Downregulating CXCL8

Shujuan Wang, Yu Liu, Yan Xu, Qianqian Hao, Luyao Shi, Yufei Chen, Yajun Liu, Mengya Li, Yu Zhang, Tao Li, Yafei Li, Zhongxing Jiang, Yanfang Liu, Chong Wang, Bian Zhilei, Lu Yang, Wenyi Lu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6133.
https://doi.org/10.1182/blood-2024-199630
Published: 2024
Journal Articles

Long Noncoding RNA NEAT1 Regulates Acute Graft-Versus-Host Disease By Promoting Macrophage M1 Polarization through JNK Pathway

Ran Zhang, Zhenli Huang, Li Wang, Weijie Cao, Donald Small, Ruiqi Zhu, Wei Shi, Zhongxing Jiang, Linghui Xia
Journal: Blood
Blood (2023) 142 (Supplement 1): 2053.
https://doi.org/10.1182/blood-2023-189758
Published: 2023
Journal Articles

The Combination of Iguratimod and Danazol Versus Danazol As a Treatment of Corticosteroid-Resistant/Relapse Immune Thrombocytopenia: A Randomized, Controlled, Multicenter, Open-Label Trial

Xiaolu Zhu, Hui Liu, Zhao Wang, Zhongxing Jiang, Liangming Ma, Min Wang, Jiamin Zhang, Zhuoyu An, Yejun Wu, Yun He, Haixia Fu, Yingjun Chang, Lanping Xu, Kaiyan Liu, Xiao Jun Huang, Xiaohui Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2589.
https://doi.org/10.1182/blood-2023-184342
Published: 2023
Journal Articles

AK117 (anti-CD47 monoclonal antibody) in Combination with Azacitidine for Newly Diagnosed Higher Risk Myelodysplastic Syndrome (HR-MDS): AK117-103 Phase 1b Results

Miao Miao, Qingliang Teng, Depei Wu, Zhongxing Jiang, Songfu Jiang, Fei Li, Yang Liang, Zhongmin Maxwell Wang, Baiyong Li, Yu Xia, Hongyan Tong
Journal: Blood
Blood (2023) 142 (Supplement 1): 1865.
https://doi.org/10.1182/blood-2023-179099
Published: 2023
Journal Articles

Efficacy and Safety of Clifutinib, a Novel, Highly Selective, Oral FLT3 Inhibitor, in Patients with FLT3-Mutated Relapsed or Refractory Acute Myeloid Leukemia：Updated Results from a Phase I Study

Jie Jin, Huafeng Wang, Wen-Juan Yu, Zheng Ge, Xudong Wei, Yuhua Li, Zhongxing Jiang, Yiqing Li, Xin Du, Linhua Yang, Lie Lin, Jishi Wang, Yazhou Yao, Xiaoping Hu, Jianping Lan, Xiuzhi Deng, Tong Chen, Xianqi Feng, Dengju Li, Ming Hou, Rong Fu, Siyong Huang, Jingbo Wang, Xin Du, Hui Yang, Haiping Yang, Yingzhi Jiang, Zhijie Wang, Deng Li, Bing Liu, Ning Kang, Yulei Zhuang, Yingjun Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4281.
https://doi.org/10.1182/blood-2023-188961
Published: 2023
Journal Articles

Humanized Monoclonal Antibody IMM47, Targeting CD24, Exhibits Exceptional Anti-Tumor Efficacy By Blocking the CD24/Siglec-10 Interaction and Can be Used As Monotherapy or in Combination with Anti-PD1 Antibodies for Cancer Immunotherapy

Jifeng Yu, Song Li, Dianze Chen, Huiqin Guo, Yanan Yang, Dandan Liu, Chunmei Yang, Xing Bai, Wei Zhang, Li Zhang, Gui Zhao, Xiaoping Tu, Liang Peng, Sijin Liu, Yongping Song, Zhongxing Jiang, Ruliang Zhang, Wenzhi Tian
Journal: Blood
Blood (2023) 142 (Supplement 1): 7140.
https://doi.org/10.1182/blood-2023-172483
Published: 2023
Journal Articles

ZGGS15, a Novel IgG4 Bispecific Monoclonal Antibody Targeting Both LAG-3 and Tigit, Demonstrates Outstanding Anti-Tumor Activity and Can be Used As Monotherapy or in Combination with Anti-PD-1 Antibodies for Cancer Immunotherapy

Jifeng Yu, Tongcheng Dai, Hao Sun, Bin Zhang, Tyler Liban, Jessica Ochoa, Jackie Sheng, Yongping Song, Zhongxing Jiang, Zelin Sheng, Binhua Lv
Journal: Blood
Blood (2023) 142 (Supplement 1): 5764.
https://doi.org/10.1182/blood-2023-184775
Published: 2023
Journal Articles

A Phase I/II Trial of the FLT3 Kinase Inhibitor XY0206 in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Junyuan Qi, Lin Song, Xudong Wei, Zhimin Zhai, Anyou Wang, Daozi Jiang, Yang Liang, Fei Li, Zhongxing Jiang, Xuejun Zhang, Qunyi Guo, Hongmei Jing, Yajing Xu, Xiangmin Tong, Jianxiang Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 2908.
https://doi.org/10.1182/blood-2023-183088
Published: 2023
Journal Articles

Efficacy, Safety, and Survival Findings after Long-Term Follow-up from ZGJAK002, a Phase 2 Study Comparing Jaktinib 100 Mg Twice Daily with 200 Mg Once Daily for Myelofibrosis (MF)

Yi Zhang, Hu Zhou, Zhongxing Jiang, Dengshu Wu, Junling Zhuang, Wei Li, Qian Jiang, Xiuli Wang, Jinwen Huang, Huanling Zhu, Linhua Yang, Xin Du, Fei Li, Ruixiang Xia, Feng Zhang, Jianda Hu, Yan Li, Yu Hu, Jing Liu, Chenghao Jin, Kai Sun, Zeping Zhou, Shanshan Suo, Wenjuan Yu, Jie Jin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1814.
https://doi.org/10.1182/blood-2023-179043
Published: 2023
Journal Articles

Oligosecretory Waldenström Macroglobulinemia Patients Exhibit Excellent Treatment Response and Outcomes

Ying Yu, Wenjie Xiong, Zanzan Wang, Yuting Yan, Jiawen Chen, Yanshan Huang, Xinxin Cao, Zhongxing Jiang, Huihan Wang, Zhen Cai, Juan Du, Chunyan Sun, Ting Niu, Guangzhong Yang, Hua Xue, Bingzong Li, Honghui Huang, Zhenling Li, Qinhua Liu, Fei Li, Ou Bai, Min Mao, Rong Fu, Ling Wang, Chunrui Li, Xiaoxia Chu, Lihong Liu, Yujun Dong, Luqun Wang, Jun Luo, Yongqiang Wei, Lugui Qiu, Jian Li, ShuHua Yi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9289–9291.
https://doi.org/10.1182/blood-2022-157311
Published: 2022
Journal Articles

Switching from Eltrombopag to Hetrombopag in Patients with Primary Immune Thrombocytopenia (ITP): Post-Hoc Analysis of a Multicenter, Randomized Phase III Trial

Yu Hu, Renchi Yang, Ting Niu, Heng Mei, Liu Xiaofan, Yan Li, Hu Zhou, Ying Feng, Guangxun Gao, Peng Cheng, Ruibin Huang, Linhua Yang, Jianda Hu, Ming Hou, Yazhou Yao, Li Liu, Yi Wang, De-Pei Wu, Xuliang Shen, Jie Jin, Jianmin Luo, Zeng Yun, Xin Zhou, Ruixiang Xiang, Zhongxing Jiang, Yuansong Bai, Junye Xiong, Runzi Li, Jianjun Zou
Journal: Blood
Blood (2022) 140 (Supplement 1): 5543–5545.
https://doi.org/10.1182/blood-2022-162945
Published: 2022
Journal Articles

Genetic Mutation Signature for Relapse Prediction in Normal Karyotype Acute Myeloid Leukemia

Lijie Han, Zhongxing Jiang, Xiaodong Lv, Jifeng Yu
Journal: Blood
Blood (2022) 140 (Supplement 1): 11814.
https://doi.org/10.1182/blood-2022-158908
Published: 2022
Journal Articles

A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome

Miao Miao, Depei WU, Shuangfeng Xie, Mei Hong, ChunKang Chang, Li Yu, Sujun Gao, Yan Li, Yuhua Li, Zunmin Zhu, Baolin Tang, Bingzong Li, Haiping Yang, Jishi Wang, Ling Qin, Rong Fu, Fei Li, Liangming Ma, Qifa Liu, Xin Du, Zhongxing Jiang, Zhenyu Li, Aijun Liu, Hongyan Tong, Jun Ma, Li Liu, Qingchi Liu, Yajing Xu, Hui Zhou, Yan Wang, Jianlin Chen, Ziru Niu, Mingxia Chen, Zhijian Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 4045–4046.
https://doi.org/10.1182/blood-2022-155901
Published: 2022
Journal Articles

Novel Sirpα-Fc Fusion Protein IMM01 Exhibits Dual Anti-Tumor Activities By Targeting CD47/Sirpα Signal Pathway

Jifeng Yu, Song Li, Dianze Chen, Dandan Liu, Huiqin Guo, Chunmei Yang, Wei Zhang, Li Zhang, Gui Zhao, Xiaoping Tu, Liang Peng, Sijin Liu, Xing Bai, Yongping Song, Zhongxing Jiang, Ruliang Zhang, Wenzhi Tian
Journal: Blood
Blood (2022) 140 (Supplement 1): 3067–3068.
https://doi.org/10.1182/blood-2022-155977
Published: 2022
Journal Articles

Results from a Phase 2 Study of a Novel Janus Kinase Inhibitor in Treatment of Patients with Myelofibrosis

Yi Zhang, Hu Zhou, Zhongxing Jiang, DengShu Wu, Junling Zhuang, Wei Li, Qian Jiang, XiuLi Wang, Jinwen Huang, Huan-Ling Zhu, RuiJuan Zhang, Xin Du, Li Fei, Ruixiang Xiang, Feng Zhang, Jianda Hu, Yan Li, Yu Hu, Jing Liu, ChengHao Jin, Kai Sun, Ze-Ping Zhou, Jie Jin
Journal: Blood
Blood (2021) 138 (Supplement 1): 387.
https://doi.org/10.1182/blood-2021-145664
Published: 2021