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Journal Articles

Single-Cell RNA Analysis of Bone Marrow Mononuclear Cells Reveals Abnormal Activation of T Cells and Monocytes, and Identifies CD35 As a Novel Biomarker and Therapeutic Target in Waldenstrom Macroglobulinemia

Hao Sun, Xia Liu, Maria Luisa Guerrera, Nickolas Tsakmaklis, Amanda Kofides, Andres Felipe Ramirez Gamero, Catherine A. Flynn, Christopher J Patterson, Mu Hao, Lugui Qiu, Shayna R Sarosiek, Jorge J. Castillo, Zachary R Hunter, Shirong Liu, Steven P. Treon

Blood (2024) 144 (Supplement 1): 743.

https://doi.org/10.1182/blood-2024-211488

Published: 2024

Journal Articles

Genomic Evolution By Serial Single-Cell Sequencing Identifies High Tumor Expression of LYN As a Promoter of Resistance in Waldenstrom's Macroglobulinemia Undergoing Ibrutinib Monotherapy

Hao Sun, Romanos Sklavenitis-Pistofidis, Xia Liu, Nickolas Tsakmaklis, Maria Luisa Guerrera, Amanda Kofides, Andres Felipe Ramirez Gamero, Catherine A. Flynn, Christopher J Patterson, Mu Hao, Lu-Gui Qiu, Shayna R Sarosiek, Jorge J. Castillo, Zachary R Hunter, Shirong Liu, Steven P. Treon

Blood (2024) 144 (Supplement 1): 4338.

https://doi.org/10.1182/blood-2024-211597

Published: 2024

Journal Articles

Determination of MYD88 and CXCR4 Mutation for Clinical Detection and Their Significance in Waldenström Macroglobulinemia

Blood (2024) 144 (Supplement 1): 4349.

https://doi.org/10.1182/blood-2024-202324

Published: 2024

Journal Articles

Discovery of Undocumented, Cancer-Specific and Pro-Inflammatory Isoforms of WNK2 That Are Highly Expressed in MYD88 Mutated Waldenström's Macroglobulinemia and Represent Novel Therapeutic Targets.

Blood (2024) 144 (Supplement 1): 2972.

https://doi.org/10.1182/blood-2024-211759

Published: 2024

Journal Articles

Multi-Omic Analysis Identifies Deletions in Chr17p and High ROR1 Expression, but Not TP53 Mutations As Predictors of Overall Survival in Patients with Untreated Waldenstrom's Macroglobulinemia (WM)

Zachary R Hunter, Andres Felipe Ramirez Gamero, Maria Luisa Guerrera, Nickolas Tsakmaklis, Amanda Kofides, Xia Liu, Shirong Liu, Abigail Peachey, Hao Sun, Catherine A. Flynn, Kirsten Meid, Joshua Gutine, Christopher J Patterson, Shayna R Sarosiek, Jorge J. Castillo, Steven P. Treon

Blood (2024) 144 (Supplement 1): 2968.

https://doi.org/10.1182/blood-2024-211664

Published: 2024

Journal Articles

Pacritinib Effectively Inhibits Pro-Survival Signaling and Overcomes BTK Cys481Ser -Mediated Resistance in MYD88-Mutated B-Cell Malignancies

Shirong Liu, Amanda Kofides, Xia Liu, Hao Sun, Alexa G Canning, Nickolas Tsakmaklis, Maria Luisa Guerrera, Christopher J Patterson, Zachary R Hunter, Kirsten Meid, Prafulla C. Gokhale, John M Hatcher, Jorge J. Castillo, Shayna R Sarosiek, Steven P. Treon

Blood (2024) 144 (Supplement 1): 5830.

https://doi.org/10.1182/blood-2024-211285

Published: 2024

Journal Articles

Single-Cell Multi-Omics Analysis Reveals Heterogeneity of Malignant Plasma Cell during Progression of Multiple Myeloma

Fangshuo Feng, Hao Sun, Xiaoyu Zhang, Xiyue Sun, Tengteng Yu, Haiqing Xiong, Gang An, Lu-Gui Qiu, Mu Hao

Blood (2024) 144 (Supplement 1): 6845.

https://doi.org/10.1182/blood-2024-203100

Published: 2024

Journal Articles

Development and Evaluation of a Multiplex Digital PCR Assay for Detecting CXCR4 S338X Mutations in Waldenstrom's Macroglobulinemia

Nickolas Tsakmaklis, Zachary R Hunter, Amanda Kofides, Xia Liu, Shirong Liu, Hao Sun, Abigail Peachey, Maria Luisa Guerrera, Christopher J Patterson, Joshua Gustine, Andrew R. Branagan, Shayna R Sarosiek, Jorge J. Castillo, Steven P. Treon

Blood (2024) 144 (Supplement 1): 6194.

https://doi.org/10.1182/blood-2024-211703

Published: 2024

Journal Articles

TRIM28 Serves As a Key Regulator of Protein Homeostasis and Mediates Proteasome Inhibitor Resistance in Multiple Myeloma

Teng Fang, Lanting Liu, Hao Sun, Xiyue Sun, Zhen Yu, Lugui Qiu, Mu Hao

Blood (2024) 144 (Supplement 1): 4668.

https://doi.org/10.1182/blood-2024-204159

Published: 2024

Journal Articles

Brentuximab Vedotin Combined with Chemotherapy in the Treatment of Pediatric Patients with R/R Hodgkin Lymphoma: Results of a Real World Setting Study

Li Ying, Nan Li, Chunju Zhou, Shuang Huang, Ling Jin, Jing Yang, Miaomiao Shao, Hao Sun, Xiaoling Wang, Yanlong Duan

Blood (2023) 142 (Supplement 1): 6209.

https://doi.org/10.1182/blood-2023-182590

Published: 2023

Journal Articles

A Novel Indirubin-3-Monoxime Derivative Functions As Regulator of Proteostasis Via Targeting TRIM28 in Multiple Myeloma

Teng Fang, Hao Sun, Xiyue Sun, Zhen Yu, Xiaoyu Zhang, Lanting Liu, Lixin Gong, Shiyi Xie, Mu Hao, Lugui Qiu

Blood (2023) 142 (Supplement 1): 6572.

https://doi.org/10.1182/blood-2023-180712

Published: 2023

Journal Articles

ZGGS15, a Novel IgG4 Bispecific Monoclonal Antibody Targeting Both LAG-3 and Tigit, Demonstrates Outstanding Anti-Tumor Activity and Can be Used As Monotherapy or in Combination with Anti-PD-1 Antibodies for Cancer Immunotherapy

Jifeng Yu, Tongcheng Dai, Hao Sun, Bin Zhang, Tyler Liban, Jessica Ochoa, Jackie Sheng, Yongping Song, Zhongxing Jiang, Zelin Sheng, Binhua Lv

Blood (2023) 142 (Supplement 1): 5764.

https://doi.org/10.1182/blood-2023-184775

Published: 2023

Journal Articles

Exosome Mirnas Profiling in Serum and Prognostic Evaluation in Patients with Multiple Myeloma

Teng Fang, Hao Sun, Mu Hao, Lugui Qiu

Blood (2022) 140 (Supplement 1): 12474–12475.

https://doi.org/10.1182/blood-2022-162902

Published: 2022

Journal Articles

Identifying the Cells of Origin and Risk-Stratification Strategy By Single-Cell Sequencing in Multiple Myeloma

Lixin Gong, Junqiang Lv, Lugui Qiu, Hao Sun, Mu Hao

Blood (2022) 140 (Supplement 1): 12473.

https://doi.org/10.1182/blood-2022-159485

Published: 2022

Journal Articles

Multiple Myeloma-Derived Mir-27b-3p Facilitates Tumor Progression Via Promoting Tumor Cell Proliferation and Immunosuppressive Microenvironment

Xiaojing Wei, Zhen Yu, Hao Sun, Lixin Gong, Lanting Liu, Teng Fang, Yi He, Tingyu Wang, Weiwei Sui, Yan Xu, Gang An, Xiaoke Ma, Lugui Qiu, Mu Hao

Blood (2022) 140 (Supplement 1): 7106–7107.

https://doi.org/10.1182/blood-2022-156759

Published: 2022

Journal Articles

Single-Cell Transcriptome Profiling Reveals Tumor Cell Heterogeneity and Immunosuppressive Microenvironment in Waldenström Macroglobulinemia

Hao Sun, Teng Fang, Tingyu Wang, Zhen Yu, Lixin Gong, Xiaojing Wei, Lugui Qiu, Mu Hao

Blood (2022) 140 (Supplement 1): 11872.

https://doi.org/10.1182/blood-2022-164483

Published: 2022

Journal Articles

Immune Profiling of MM Microenvironment at Single-Cell Resolution

Lixin Gong, Hao Sun, Junqiang Lv, Lugui Qiu, Mu Hao

Blood (2022) 140 (Supplement 1): 9976–9977.

https://doi.org/10.1182/blood-2022-162341

Published: 2022

Journal Articles

Identification of Myeloma-Initiating Cells By Single-Cell RNA Sequencing

Lixin Gong, Hao Sun, Junqiang Lv, Xiaojing Wei, Lanting Liu, Zhen Yu, Yi He, Gang An, Dehui Zou, Lugui Qiu, Mu Hao

Blood (2021) 138 (Supplement 1): 2646.

https://doi.org/10.1182/blood-2021-148275

Published: 2021

Journal Articles

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β 2 -integrin and neutrophil arrest from rolling

Lai Wen, Alex Marki, Payel Roy, Sara McArdle, Hao Sun, Zhichao Fan, Alexandre R. Gingras, Mark H. Ginsberg, Klaus Ley

Blood (2021) 137 (1): 29–38.

https://doi.org/10.1182/blood.2019003446

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Differential Use of Rap1 Effectors for Integrin Activation in Platelets and Lymphocytes

Frederic Lagarrigue, PhD, Hao Sun, PhD, Alexandre R Gingras, PhD, Mark H Ginsberg, MD

Blood (2020) 136 (Supplement 1): 27–28.

https://doi.org/10.1182/blood-2020-142720

Published: 2020

NARROW

Single-Cell RNA Analysis of Bone Marrow Mononuclear Cells Reveals Abnormal Activation of T Cells and Monocytes, and Identifies CD35 As a Novel Biomarker and Therapeutic Target in Waldenstrom Macroglobulinemia

Genomic Evolution By Serial Single-Cell Sequencing Identifies High Tumor Expression of LYN As a Promoter of Resistance in Waldenstrom's Macroglobulinemia Undergoing Ibrutinib Monotherapy

Determination of MYD88 and CXCR4 Mutation for Clinical Detection and Their Significance in Waldenström Macroglobulinemia

Discovery of Undocumented, Cancer-Specific and Pro-Inflammatory Isoforms of WNK2 That Are Highly Expressed in MYD88 Mutated Waldenström's Macroglobulinemia and Represent Novel Therapeutic Targets.

Multi-Omic Analysis Identifies Deletions in Chr17p and High ROR1 Expression, but Not TP53 Mutations As Predictors of Overall Survival in Patients with Untreated Waldenstrom's Macroglobulinemia (WM)

Pacritinib Effectively Inhibits Pro-Survival Signaling and Overcomes BTK Cys481Ser -Mediated Resistance in MYD88-Mutated B-Cell Malignancies

Single-Cell Multi-Omics Analysis Reveals Heterogeneity of Malignant Plasma Cell during Progression of Multiple Myeloma

Development and Evaluation of a Multiplex Digital PCR Assay for Detecting CXCR4 S338X Mutations in Waldenstrom's Macroglobulinemia

TRIM28 Serves As a Key Regulator of Protein Homeostasis and Mediates Proteasome Inhibitor Resistance in Multiple Myeloma

Brentuximab Vedotin Combined with Chemotherapy in the Treatment of Pediatric Patients with R/R Hodgkin Lymphoma: Results of a Real World Setting Study

A Novel Indirubin-3-Monoxime Derivative Functions As Regulator of Proteostasis Via Targeting TRIM28 in Multiple Myeloma

ZGGS15, a Novel IgG4 Bispecific Monoclonal Antibody Targeting Both LAG-3 and Tigit, Demonstrates Outstanding Anti-Tumor Activity and Can be Used As Monotherapy or in Combination with Anti-PD-1 Antibodies for Cancer Immunotherapy

Exosome Mirnas Profiling in Serum and Prognostic Evaluation in Patients with Multiple Myeloma

Identifying the Cells of Origin and Risk-Stratification Strategy By Single-Cell Sequencing in Multiple Myeloma

Multiple Myeloma-Derived Mir-27b-3p Facilitates Tumor Progression Via Promoting Tumor Cell Proliferation and Immunosuppressive Microenvironment

Single-Cell Transcriptome Profiling Reveals Tumor Cell Heterogeneity and Immunosuppressive Microenvironment in Waldenström Macroglobulinemia

Immune Profiling of MM Microenvironment at Single-Cell Resolution

Identification of Myeloma-Initiating Cells By Single-Cell RNA Sequencing

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β 2 -integrin and neutrophil arrest from rolling

Differential Use of Rap1 Effectors for Integrin Activation in Platelets and Lymphocytes

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