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Journal Articles

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β 2 -integrin and neutrophil arrest from rolling

Lai Wen, Alex Marki, Payel Roy, Sara McArdle, Hao Sun, Zhichao Fan, Alexandre R. Gingras, Mark H. Ginsberg, Klaus Ley

Blood (2021) 137 (1): 29–38.

https://doi.org/10.1182/blood.2019003446

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Differential Use of Rap1 Effectors for Integrin Activation in Platelets and Lymphocytes

Frederic Lagarrigue, PhD, Hao Sun, PhD, Alexandre R Gingras, PhD, Mark H Ginsberg, MD

Blood (2020) 136 (Supplement 1): 27–28.

https://doi.org/10.1182/blood-2020-142720

Published: 2020

Journal Articles

Talin-1 is the principal platelet Rap1 effector of integrin activation

Frederic Lagarrigue, David S. Paul, Alexandre R. Gingras, Andrew J. Valadez, Hao Sun, Jenny Lin, Monica N. Cuevas, Jailal N. Ablack, Miguel Alejandro Lopez-Ramirez, Wolfgang Bergmeier, Mark H. Ginsberg

Blood (2020) 136 (10): 1180–1190.

https://doi.org/10.1182/blood.2020005348

Published: 2020

Includes: Supplemental data

Journal Articles

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice

Miguel Alejandro Lopez-Ramirez, Angela Pham, Romuald Girard, Tine Wyseure, Preston Hale, Atsuki Yamashita, Janne Koskimäki, Sean Polster, Laleh Saadat, Ignacio A. Romero, Charles T. Esmon, Frederic Lagarrigue, Issam A. Awad, Laurent O. Mosnier, Mark H. Ginsberg

Blood (2019) 133 (3): 193–204.

https://doi.org/10.1182/blood-2018-06-856062

Published: 2019

Includes: Supplemental data

Journal Articles

The Rap1-RIAM-talin axis of integrin activation and blood cell function

Frederic Lagarrigue, Chungho Kim, Mark H. Ginsberg

Blood (2016) 128 (4): 479–487.

https://doi.org/10.1182/blood-2015-12-638700

Published: 2016

Journal Articles

Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor

Zhongji Liao, Hisashi Kato, Manjula Pandey, Joseph M. Cantor, Ararat J. Ablooglu, Mark H. Ginsberg, Sanford J. Shattil

Blood (2015) 125 (12): 1995–2004.

https://doi.org/10.1182/blood-2014-09-603035

Published: 2015

Includes: Supplemental data

Journal Articles

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

Andrea S Rothmeier, PhD, Patrizia Marchese, PhD, Christian Furlan-Freguia, PhD, Brian G. Petrich, PhD, Mark H. Ginsberg, MD, Zaverio M Ruggeri, MD, Wolfram Ruf, MD

Blood (2014) 124 (21): 2806.

https://doi.org/10.1182/blood.V124.21.2806.2806

Published: 2014

Journal Articles

ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding

Ana Kasirer-Friede, Jian Kang, Bryan Kahner, Feng Ye, Mark H. Ginsberg, Sanford J. Shattil

Blood (2014) 123 (20): 3156–3165.

https://doi.org/10.1182/blood-2013-08-520627

Published: 2014

Includes: Supplemental data

Journal Articles

IGN523: A Therapeutic Anti-CD98 Antibody With Multiple Mechanisms Of Action Demonstrates Anti-Tumor Efficacy

Gregory M. Hayes, Lawrence Chinn, Joseph M. Cantor, Timothy Velilla, Mark H. Ginsberg, Edward H. van der Horst

Blood (2013) 122 (21): 1462.

https://doi.org/10.1182/blood.V122.21.1462.1462

Published: 2013

Journal Articles

Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor.

Andrea S Rothmeier, Ph.D., Christian Furlan-Freguia, Ph.D., Brian G. Petrich, PhD, Patrizia Marchese, PhD, Zaverio M. Ruggeri, MD, PhD, Mark H. Ginsberg, M.D., Wolfram Ruf, MD

Blood (2012) 120 (21): 2218.

https://doi.org/10.1182/blood.V120.21.2218.2218

Published: 2012

Journal Articles

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

Craig T. Lefort, Jan Rossaint, Markus Moser, Brian G. Petrich, Alexander Zarbock, Susan J. Monkley, David R. Critchley, Mark H. Ginsberg, Reinhard Fässler, Klaus Ley

Blood (2012) 119 (18): 4275–4282.

https://doi.org/10.1182/blood-2011-08-373118

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Reconstruction of integrin activation

Feng Ye, Chungho Kim, Mark H. Ginsberg

Blood (2012) 119 (1): 26–33.

https://doi.org/10.1182/blood-2011-04-292128

Published: 2012

Journal Articles

CD61/ Integrin β3 Ligation Contributes to the Thrombopoietin-Mediated Niche Function of Mouse Hematopoietic Stem Cells.

Terumasa Umemoto, Masayuki Yamato, Yoshiko Shiratsuchi, Kenji Tsukada, Mika Utsumi, Yohei Morita, Masato Terasawa, Takehiko Shibata, Kohji Nishida, Yoshiro Kobayashi, Brian G Petrich, Mark H Ginsberg, Hiromitsu Nakauchi, Koji Eto, Teruo Okano

Blood (2009) 114 (22): 383.

https://doi.org/10.1182/blood.V114.22.383.383

Published: 2009

Journal Articles

Interactions of platelet integrin α ΙΙb and β 3 transmembrane domains in mammalian cell membranes and their role in integrin activation

Chungho Kim, Tong-Lay Lau, Tobias S. Ulmer, Mark H. Ginsberg

Blood (2009) 113 (19): 4747–4753.

https://doi.org/10.1182/blood-2008-10-186551

Published: 2009

Includes: Supplemental data

Journal Articles

Antithrombotic effects of targeting αIIbβ3 signaling in platelets

Ararat J. Ablooglu, Jian Kang, Brian G. Petrich, Mark H. Ginsberg, Sanford J. Shattil

Blood (2009) 113 (15): 3585–3592.

https://doi.org/10.1182/blood-2008-09-180687

Published: 2009

Includes: Supplemental data

Journal Articles

UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin αIIbβ3

Robin Verhaar, David W. C. Dekkers, Iris M. De Cuyper, Mark H. Ginsberg, Dirk de Korte, Arthur J. Verhoeven

Blood (2008) 112 (13): 4935–4939.

https://doi.org/10.1182/blood-2008-04-151043

Published: 2008

Includes: Supplemental data

Journal Articles

Anti-Thrombotic Effects of Targeting Outside-in αIIbβ3 Signaling in Platelets

Ararat J. Ablooglu, Ph.D., Jian Kang, Ph.D., Brian G. Petrich, Ph.D., Mark H. Ginsberg, M.D., Sanford J. Shattil, M.D.

Blood (2008) 112 (11): 411.

https://doi.org/10.1182/blood.V112.11.411.411

Published: 2008

Journal Articles

Just a Drop of Blood: Exploration of Shear-Dependent Platelet Adhesion and Activation in Microfluidic Devices.

Ana Kasirer-Friede, PhD, Edgar Gutierrez, PhD, Brian Petrich, PhD, Sanford J. Shattil, MD, Mark H. Ginsberg, MD, Alex Groisman, PhD

Blood (2007) 110 (11): 3650.

https://doi.org/10.1182/blood.V110.11.3650.3650

Published: 2007

Journal Articles

On the Yellow Brick Road to Platelet GP IIb-IIIa (Integrin αIIbβ3) Activation.

Naohide Watanabe, MD, Jaewon Han, Ph.D., C. James Lim, Ph.D, Alessandra Soriani, Ph.D., Wilma Puzon-McLaughlin, Esther M. LaFuente, Ph.D., Vassiliki A. Boussiotis, M.D., Ph.D., Mark H. Ginsberg, M.D., Sanford J. Shattil, M.D.

Blood (2006) 108 (11): 211.

https://doi.org/10.1182/blood.V108.11.211.211

Published: 2006

Journal Articles

Soluble VCAM-1 binding to α4 integrins is cell-type specific and activation dependent and is disrupted during apoptosis in T cells

David M. Rose, Pina M. Cardarelli, Ronald R. Cobb, Mark H. Ginsberg

Blood (2000) 95 (2): 602–609.

https://doi.org/10.1182/blood.V95.2.602

Published: 2000

NARROW

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β 2 -integrin and neutrophil arrest from rolling

Differential Use of Rap1 Effectors for Integrin Activation in Platelets and Lymphocytes

Talin-1 is the principal platelet Rap1 effector of integrin activation

Cerebral cavernous malformations form an anticoagulant vascular domain in humans and mice

The Rap1-RIAM-talin axis of integrin activation and blood cell function

Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor

A Crucial Role for Caspase 1 in Thrombo-Inflammatory Microparticle Release

ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding

IGN523: A Therapeutic Anti-CD98 Antibody With Multiple Mechanisms Of Action Demonstrates Anti-Tumor Efficacy

Thrombosis and Inflammation Are Coupled by a Common Thioredoxin Reductase Pathway Downstream of the P2×7 Receptor.

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

Reconstruction of integrin activation

CD61/ Integrin β3 Ligation Contributes to the Thrombopoietin-Mediated Niche Function of Mouse Hematopoietic Stem Cells.

Interactions of platelet integrin α ΙΙb and β 3 transmembrane domains in mammalian cell membranes and their role in integrin activation

Antithrombotic effects of targeting αIIbβ3 signaling in platelets

UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin αIIbβ3

Anti-Thrombotic Effects of Targeting Outside-in αIIbβ3 Signaling in Platelets

Just a Drop of Blood: Exploration of Shear-Dependent Platelet Adhesion and Activation in Microfluidic Devices.

On the Yellow Brick Road to Platelet GP IIb-IIIa (Integrin αIIbβ3) Activation.

Soluble VCAM-1 binding to α4 integrins is cell-type specific and activation dependent and is disrupted during apoptosis in T cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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