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Journal Articles

A key role for platelet GPVI in neutrophil recruitment, migration, and NETosis in the early stages of acute lung injury

Philipp Burkard, Charlotte Schonhart, Timo Vögtle, David Köhler, Linyan Tang, Denise Johnson, Katherina Hemmen, Katrin G. Heinze, Alexander Zarbock, Heike M. Hermanns, Peter Rosenberger, Bernhard Nieswandt

Blood (2023) 142 (17): 1463–1477.

https://doi.org/10.1182/blood.2023019940

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

Neutrophils in acute inflammation: current concepts and translational implications

Andreas Margraf, Clifford A. Lowell, Alexander Zarbock

Blood (2022) 139 (14): 2130–2144.

https://doi.org/10.1182/blood.2021012295

Published: 2022

Journal Articles

Kindlin-3: at the right place at the right time

Andreas Margraf, Alexander Zarbock

Blood (2021) 137 (1): 1–2.

https://doi.org/10.1182/blood.2020008359

Published: 2021

Journal Articles

The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β 2 -integrin LFA-1

Andreas Margraf, Giulia Germena, Hannes C. A. Drexler, Jan Rossaint, Nadine Ludwig, Barbara Prystaj, Sina Mersmann, Katharina Thomas, Helena Block, Wiebke Gottschlich, Chang Liu, Peter W. Krenn, Hermann Haller, Barbara Heitplatz, Marika Meyer zu Brickwedde, Markus Moser, Dietmar Vestweber, Alexander Zarbock

Blood (2020) 136 (19): 2200–2205.

https://doi.org/10.1182/blood.2020004948

Published: 2020

Includes: Supplemental data

Journal Articles

L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling

Anika Cappenberg, Andreas Margraf, Katharina Thomas, Bernadette Bardel, Dylan A. McCreedy, Veerle Van Marck, Alexander Mellmann, Clifford A. Lowell, Alexander Zarbock

Blood (2019) 134 (17): 1445–1457.

https://doi.org/10.1182/blood.2019000685

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

STIMulation of signaling in neutrophils

Anika Stadtmann, Alexander Zarbock

Blood (2017) 130 (13): 1488–1490.

https://doi.org/10.1182/blood-2017-08-798512

Published: 2017

Journal Articles

Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo

Helena Block, Anika Stadtmann, Daniel Riad, Jan Rossaint, Charlotte Sohlbach, Giulia Germena, Dianqing Wu, Scott I. Simon, Klaus Ley, Alexander Zarbock

Blood (2016) 127 (3): 314–324.

https://doi.org/10.1182/blood-2015-06-651034

Published: 2016

Includes: Supplemental data

Journal Articles

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap–mediated sterile inflammation

Jan Rossaint, Jan M. Herter, Hugo Van Aken, Markus Napirei, Yvonne Döring, Christian Weber, Oliver Soehnlein, Alexander Zarbock

Blood (2014) 123 (16): 2573–2584.

https://doi.org/10.1182/blood-2013-07-516484

Published: 2014

Includes: Supplemental data

Journal Articles

Coordinated and unique functions of the E-selectin ligand ESL-1 during inflammatory and hematopoietic recruitment in mice

Vinatha Sreeramkumar, Magdalena Leiva, Anika Stadtmann, Christophe Pitaval, Inés Ortega-Rodríguez, Martin K. Wild, Brendan Lee, Alexander Zarbock, Andrés Hidalgo

Blood (2013) 122 (24): 3993–4001.

https://doi.org/10.1182/blood-2013-07-514497

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

β2-integrin activity: the role of thiols

Alexander Zarbock

Blood (2013) 121 (19): 3779–3780.

https://doi.org/10.1182/blood-2013-03-489872

Published: 2013

Journal Articles

Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling

Jan M. Herter, Jan Rossaint, Helena Block, Heidi Welch, Alexander Zarbock

Blood (2013) 121 (12): 2301–2310.

https://doi.org/10.1182/blood-2012-09-457085

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

The shady side of dasatinib

Alexander Zarbock

Blood (2012) 119 (21): 4817–4818.

https://doi.org/10.1182/blood-2012-03-418582

Published: 2012

Journal Articles

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

Craig T. Lefort, Jan Rossaint, Markus Moser, Brian G. Petrich, Alexander Zarbock, Susan J. Monkley, David R. Critchley, Mark H. Ginsberg, Reinhard Fässler, Klaus Ley

Blood (2012) 119 (18): 4275–4282.

https://doi.org/10.1182/blood-2011-08-373118

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow

Alexander Zarbock, Klaus Ley, Rodger P. McEver, Andrés Hidalgo

Blood (2011) 118 (26): 6743–6751.

https://doi.org/10.1182/blood-2011-07-343566

Published: 2011

Journal Articles

Adam17 -dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites

Jingjing Tang, Alexander Zarbock, Ivan Gomez, Carole L. Wilson, Craig T. Lefort, Anika Stadtmann, Bridgit Bell, Li-Chuan Huang, Klaus Ley, Elaine W. Raines

Blood (2011) 118 (3): 786–794.

https://doi.org/10.1182/blood-2010-11-321406

Published: 2011

Includes: Supplemental data

Journal Articles

von Willebrand factor promotes leukocyte extravasation

Björn Petri, Andre Broermann, Hang Li, Alexander G. Khandoga, Alexander Zarbock, Fritz Krombach, Tobias Goerge, Stefan W. Schneider, Claire Jones, Bernhard Nieswandt, Martin K. Wild, Dietmar Vestweber

Blood (2010) 116 (22): 4712–4719.

https://doi.org/10.1182/blood-2010-03-276311

Published: 2010

Includes: Supplemental data

Journal Articles

CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis

M. Gabriele Bixel, Hang Li, Bjoern Petri, Alexander G. Khandoga, Andrej Khandoga, Alexander Zarbock, Karen Wolburg-Buchholz, Hartwig Wolburg, Lydia Sorokin, Dagmar Zeuschner, Sigrid Maerz, Stefan Butz, Fritz Krombach, Dietmar Vestweber

Blood (2010) 116 (7): 1172–1184.

https://doi.org/10.1182/blood-2009-12-256388

Published: 2010

Includes: Supplemental data

Journal Articles

Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils

Yoshihiro Kuwano, Oliver Spelten, Hong Zhang, Klaus Ley, Alexander Zarbock

Blood (2010) 116 (4): 617–624.

https://doi.org/10.1182/blood-2010-01-266122

Published: 2010

Includes: Multimedia, Supplemental data

Journal Articles

Tyrosine kinase Btk regulates E-selectin–mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways

Helena Mueller, Anika Stadtmann, Hugo Van Aken, Emilio Hirsch, Demin Wang, Klaus Ley, Alexander Zarbock

Blood (2010) 115 (15): 3118–3127.

https://doi.org/10.1182/blood-2009-11-254185

Published: 2010

Includes: Supplemental data

Journal Articles

Gα i2 is required for chemokine-induced neutrophil arrest

Alexander Zarbock, Tracy L. Deem, Tracy L. Burcin, Klaus Ley

Blood (2007) 110 (10): 3773–3779.

https://doi.org/10.1182/blood-2007-06-094565

Published: 2007

NARROW

A key role for platelet GPVI in neutrophil recruitment, migration, and NETosis in the early stages of acute lung injury

Neutrophils in acute inflammation: current concepts and translational implications

Kindlin-3: at the right place at the right time

The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β 2 -integrin LFA-1

L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling

STIMulation of signaling in neutrophils

Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap–mediated sterile inflammation

Coordinated and unique functions of the E-selectin ligand ESL-1 during inflammatory and hematopoietic recruitment in mice

β2-integrin activity: the role of thiols

Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling

The shady side of dasatinib

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

Leukocyte ligands for endothelial selectins: specialized glycoconjugates that mediate rolling and signaling under flow

Adam17 -dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites

von Willebrand factor promotes leukocyte extravasation

CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis

Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils

Tyrosine kinase Btk regulates E-selectin–mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways

Gα i2 is required for chemokine-induced neutrophil arrest

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American Society of Hematology

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American Society of Hematology

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