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Journal Articles

Comprehensive Clinical and Molecular Characterization Reveals Rara As the Most Frequent Torque Teno Mini Virus Insertion Site and Defines a Distinct Ttmv::Rara Driven APL-like Leukemia Subtype

Shu Sun, Yongjing Liu, Qing-Yu Xu, Xiaosu Zhou, Lijun Wen, Li Chen, Jiaqi Chen, Huili Wang, Xue Chen, Jiacheng Lou, Huyong Zheng, Yangyang Xie, Linya Wang, Futian Ma, Lihua Yang, Xianjing Wang, Wen Gao, Yin Wu, Leping Zhang, Shuhong Shen, Suning Chen, Kankan Wang, Hongxing Liu, Jinyan Huang, Hong-Hu Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1547.
https://doi.org/10.1182/blood-2024-202323
Published: 2024
Journal Articles

Full-Spectrum Flow Cytometry Analysis Reveals Dynamics of T Cell Function of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia during Continuous Infusion of Blinatumomab

Mingying Zhang, Yuanyuan Zhang, Peijing Qi, Wei Lin, Ying Wu, Jiaole Yu, Huyong Zheng, Ruidong Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 5922.
https://doi.org/10.1182/blood-2024-209220
Published: 2024
Journal Articles

Efficacy and Safety of Adding Blinatumomab to First-Line Treatment for Chinese Children with B-Cell Acute Lymphoblastic Leukemia

Peijing Qi, Yuanyuan Zhang, Ying Wu, Jiaole Yu, Jia Fan, Wei Lin, Huyong Zheng, Ruidong Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 312.
https://doi.org/10.1182/blood-2024-199937
Published: 2024
Journal Articles

Single-Cell Sequencing Analysis Reveals Cellular Dynamics Underlying Different Responses to Blinatumomab in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Mingying Zhang, Yuanyuan Zhang, Peijing Qi, Wei Lin, Ying Wu, Jiaole Yu, Huyong Zheng, Ruidong Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4214.
https://doi.org/10.1182/blood-2024-204307
Published: 2024
Journal Articles

Critical role of tripartite fusion and LBD truncation in certain RARA - and all RARG -related atypical APL

Xiaosu Zhou, Xue Chen, Jiaqi Chen, Lijun Wen, Zhanglin Zhang, Ya-Zhen Qin, Panxiang Cao, Haizhou Xing, Yingchang Mi, Wei Wang, Guangsen Zhang, Ji Li, Huanling Wu, Zhifen Zhang, Jian Zhang, Zhan Su, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Ping Wu, Tong Wang, Gaowei Fan, Yang Zhao, David Jin, Xian Zhang, Xiujuan Ma, Qisheng Wu, Zhihua Zhang, Linya Wang, Futian Ma, Xia Xiao, Chengye Wu, Kai Sun, Ruijie Tang, Yun Zhang, Sanyun Wu, Ran Gao, Leping Zhang, Huyong Zheng, Yanli Zhao, Hong-Hu Zhu, Daopei Lu, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2024) 144 (14): 1471–1485.
https://doi.org/10.1182/blood.2024023883
Published: 2024
Includes: Supplemental data
Journal Articles

The Ingenious Multiple Efficacies of the Integrated Gene Fragment of Torque Teno Mini Virus in Orchestrating Promyelocytic Leukemogenesis Via Hijacking Rara

Xiaosu Zhou, Xue Chen, Jiaqi Chen, Panxiang Cao, Fang Wang, Yang Zhang, Xiaoli Ma, Jiancheng Fang, Linya Wang, Lijun Wen, Ping Wu, Ruijie Tang, Wanting He, Siyuan Liu, David Jin, Xian Zhang, Suning Chen, Huyong Zheng, Peihua Lu, Hongxing Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1576.
https://doi.org/10.1182/blood-2023-185426
Published: 2023
Journal Articles

Partner Gene Associated Trinary Fusion and Orchestration of Multiple Molecular Events in Acute Promyelocytic Leukemia with Variant Rara Fusion Genes

Jiaqi Chen, Lijun Wen, Xiaosu Zhou, Xue Chen, Zhanglin Zhang, Panxiang Cao, Fang Wang, Yang Zhang, Xiaoli Ma, Jiangcheng Fang, Ping Wu, Tong Wang, Zhihua Zhang, Linya Wang, Huyong Zheng, Ruijie Tang, Wei Wang, Wanting He, Siyuan Liu, David Jin, Xian Zhang, Peihua Lu, Suning Chen, Hongxing Liu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1414.
https://doi.org/10.1182/blood-2023-187869
Published: 2023
Journal Articles

Short-Term Efficacy and Safety of Blinatumomab in Early Postinduction Intensification Therapy for Pediatric B-Cell Acute Lymphoblastic Leukemia

Yanming Li, Peijing Qi, Ying Wu, Jiaole Yu, Yuanyuan Zhang, Huiqing Liu, Bei Hou, Jie Yang, Huyong Zheng, Tianyou Wang, Ruidong Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 5901.
https://doi.org/10.1182/blood-2023-188669
Published: 2023
Journal Articles

A Study on Heterogeneity and Early Response to Chemotherapy in Pediatric ETV6-RUNX1 Positive Acute Lymphoblastic Leukemia By RNA-Seq Expression Profile

Xueling Zheng, Chunyu Zhou, Ruidong Zhang, Chao Gao, Jingdong Han, Tianyou Wang, Huyong Zheng
Journal: Blood
Blood (2023) 142 (Supplement 1): 6060.
https://doi.org/10.1182/blood-2023-184389
Published: 2023
Journal Articles

Homoharringtonine-Based Induction Regimens Combined with ATRA-Based Maintenance in Chinese Pediatric AML: A Report from the Cclg-AML 2015 Protocol Study

Jing Li, Ju Gao, Ansheng Liu, Wei Liu, Hao Xiong, Changda Liang, Yongjun Fang, Yunpeng Dai, Jingbo Shao, Hui Yu, Lingzhen Wang, Li Wang, Liangchun Yang, Mei Yan, Xiaowen Zhai, Xiaodong Shi, Xin Tian, Xiuli Ju, Yan Chen, Jing Wang, Leping Zhang, Hui Liang, Sen Chen, Jingrong Zhang, Haixia Cao, Jiao Jin, Qun Hu, Junlan Wang, Yilin Wang, Min Zhou, Yueqin Han, Rong Zhang, Weihong Zhao, Aimin Li, Limin Lin, Ruidong Zhang, Chao Gao, Liting Xu, Yuanyuan Zhang, Jia Fan, Ying Wu, Wei Lin, Jiaole Yu, Peijing Qi, Pengli Huang, Xiaoxia Peng, Yaguang Peng, Huyong Zheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 3189–3191.
https://doi.org/10.1182/blood-2022-165737
Published: 2022
Journal Articles

CAR-T Therapy for a Child with Refractory Inflammatory Myofibroblastic Tumor

Kai Wang, Yan Liu, Lung-Ji Chang, Huyong Zheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10355–10356.
https://doi.org/10.1182/blood-2022-165248
Published: 2022
Journal Articles

CAR2.0 Therapy for the Management of Post-Transplantation Relapse of B-Cell Acute Lymphoblastic Leukemia

Rui Zhang, MSc, Juan Xiao, MD PhD, Zhouyang Liu, MSc, Yuan Sun, MD, Sanfang Tu, MD& PhD, Yuhua Li, MD& PhD, Leping Zhang, MD PhD, Yifei Cheng, MD PhD, Song Xue, MSc, Yongping Zhang, MD PhD, Kai Wang, MD PhD, Bin Wang, MD MSc, Huyong Zheng, MD PhD, Nobuhiro Nishio, MD PhD, Yoshiyuki Takahashi, MD PhD, Jia Feng, MD PhD, Haichan Xu, MD PhD, Yuchen Liu, MSc, Yuchen Li, MSc, Cheng Jiao, MD PhD, Biljana N. Horn, MD, Lung-Ji Chang, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7.
https://doi.org/10.1182/blood-2020-141531
Published: 2020
Journal Articles

Pilot Study on the Safety of Intravenous Arsenic Trioxide and Oral Realgar-Indigo Naturalis Formula Administrated in Children with Acute Promyelocytic Leukemia: A Single-Center Study

Linya Wang, MD, Yuanyuan Zhang, MD, Ruidong Zhang, MD PhD, Jiaole Yu, PhD MD, Ying Wu, MD, Wei Lin, Peijing Qi, Jia Fan, Jing Li, PhD, Jiayan Lin, Xueling Zheng, Hairu Hu, Xiaoxia Peng, Hui Jiang, PhD, Huyong Zheng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2611.
https://doi.org/10.1182/blood-2019-128196
Published: 2019
Journal Articles

A Multicenter Randomized Non-Inferiority Study of Homoharringtonine Versus Etoposide in Induction Phase for Chinese Childhood Acute Myeloid Leukemia - a Report from China Children's Leukemia Group (CCLG)

Jing Li, PhD, Jiaole Yu, PhD MD, Ruidong Zhang, MD PhD, Ju Gao, PhD, Changda Liang, MD PhD, Ansheng Liu, Wei Liu, Lijun Qu, Yufeng Liu, Hongsheng Wang, MD, Minghua Yang, MD, Yunpeng Dai, PhD, Hui Jiang, PhD, Yongjun Fang, PhD, Lirong SUN, PhD, Xiuli Ju, Xin Tian, PhD, Jianxin Li, Xiaodong Shi, MD, Li Wang, Leping Zhang, PhD, Runming Jin, MD, Yan Chen, MD, Guoping Hao, MD, Mei Yan, MD, Hui Liang, Cuimin Zheng, Sen Chen, Jingrong Zhang, Haixia Cao, Kaili Pan, PhD, Qun Hu, MD PhD, Zhixu He, MD, Min Zhou, Weihong Zhao, PhD, Yilin Wang, Rong Zhang, MDand PhD, Yueqin Han, Aimin Li, Huyong Zheng, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1356.
https://doi.org/10.1182/blood-2019-127932
Published: 2019
Journal Articles

Durable Remission after Salvage Chemotherapy with Combining Bortezomib and Vorinostat Followed By CD19 CAR-T Therapy in a Patient with MLL-Rearranged ALL after Early Relapse Post Allogeneic Hematopoietic Stem Cell Transplantation

Nobuhiro Nishio, MD PhD, Kai Wang, MDPhD, Kotaro Narita, MD, Shinsuke Kataoka, MD, Hironobu Kitazawa, MD, Motoharu Hamada, MD, Daisuke Ichikawa, MD, Rieko Taniguchi, MD, Norihiro Murakami, MD, Daiei Kojima, MD, Kyogo Suzuki, MD, Nozomu Kawashima, MD PhD, Eri Nishikawa, MD PhD, Yusuke Okuno, MD PhD, Atsushi Narita, MD PhD, Hideki Muramatsu, MD PhD, Asahito Hama, Shih-Ting Tsao, MSc, Maoquan Qin, MDPhD, Huyong Zheng, MD PhD, Lung-Ji Chang, PhD, Seiji Kojima, MD PhD, Yoshiyuki Takahashi, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3334.
https://doi.org/10.1182/blood.V130.Suppl_1.3334.3334
Published: 2017
Journal Articles

Clinical Characteristics & Outcome of Adolescent Patients with Acute Lymphoblastic Leukemia

Jiaole Yu, PhD MD, Ruidong Zhang, MD PhD, Jing Xie, MD, Yuanyuan Zhang, MD, Ying Wu, MD, Chao Gao, Wei Lin, Huyong Zheng, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5007.
https://doi.org/10.1182/blood.V130.Suppl_1.5007.5007
Published: 2017
Journal Articles

Germline Genetic Variations in Methotrexate Candidate Genes Are Associated with Pharmacokinetics and Outcome in Pediatric Acute Lymphoblastic Leukemia in China

Shuguang Liu, PhD, Chao Gao, Associate Researcher, Ruidong Zhang, Xiaoxi Zhao, Lei Cui, Weijing Li, Huyong Zheng, MD PhD, Zhigang Li, PhD
Journal: Blood
Blood (2016) 128 (22): 1595.
https://doi.org/10.1182/blood.V128.22.1595.1595
Published: 2016
Journal Articles

Safety and Efficacy Evaluation of 4SCAR19 Chimeric Antigen Receptor-Modified T Cells Targeting B Cell Acute Lymphoblastic Leukemia - Three-Year Follow-up of a Multicenter Phase I/II Study

Lung-Ji Chang, PhD, Lujia Dong, MD, Yu-Chen Liu, MSc, Shih-Ting Tsao, MSc, Ya-Chen Li, PhD, Li Liu, MD, Zhiyong Gao, MD, Xiyou Tan, MD, Dao-Pei Lu, MD, Jian-Ping Zhang, Jing-Bo Wang, Yu-Ming Ying, MD, Le-Ping Zhang, MD, Huyong Zheng, MD PhD, Kai Wang, MD PhD, Xiao-Li Zheng, MD, Heng-Xiang Wang, MD, Xun Lai, MD, Dong Li, MD
Journal: Blood
Blood (2016) 128 (22): 587.
https://doi.org/10.1182/blood.V128.22.587.587
Published: 2016
Journal Articles

The Isoform II of SRSF1: A Potential Biomarker in the Progression of Pediatric Acute Lymphoblastic Leukemia

Liting Xu, Huyong Zheng, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5275.
https://doi.org/10.1182/blood.V128.22.5275.5275
Published: 2016
Journal Articles

DNMT3A Mutation inChinese Childhood Acute Myeloid Leukemia

Weijing Li, Chao Gao, Associate Researcher, Lei Cui, Shuguang Liu, PhD, Xiaoxi Zhao, Ruidong Zhang, Huyong Zheng, MD PhD, Minyuan WU, MD, Zhigang Li, PhD
Journal: Blood
Blood (2016) 128 (22): 5227.
https://doi.org/10.1182/blood.V128.22.5227.5227
Published: 2016