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Journal Articles

Fetal context conveys heritable protection against MLL-rearranged AML that depends on MLL3

Jonny Mendoza-Castrejon, Wei Yang, Elisabeth Denby, Helen C. Wang, Emily B. Casey, Rohini Muthukumar, Riddhi M. Patel, Jihye Yoon, Yanan Li, J. Michael White, Ran Chen, Luis F. Z. Batista, Jeffrey A. Magee

Blood (2026) 147 (1): 61–72.

https://doi.org/10.1182/blood.2025029686

Published: 2026

Includes: Supplemental data

Journal Articles

NUP98-rearranged pediatric AML is sustained by a conserved leukemia stem cell program with SPNS2/3 as a targetable vulnerability

Jihye Yoon, Elisabeth Denby, Wei Yang, Run Zhang, Masayuki Umeda, Tingting Hu, Jonny Mendoza-Castrejon, Yanan Li, Emily Casey, Riddhi Patel, J. Michael White, Jeffery Klco, Jeffrey Magee

Blood (2025) 146 (Supplement 1): 5002.

https://doi.org/10.1182/blood-2025-5002

Published: 2025

Journal Articles

Palbociclib combined with venetoclax and azacitidine in NUP98-rearranged pediatric AML: A multicenter phase II trial demonstrating durable remission and survival benefit

Hongbo Chen, Huan Xu, Jia Fan, Wei Liu, Xiaoyan Wu, Jiawei Xu, Jie Yang, Yu Lu, Yanna Mao, Fengli Lan, Beibei Li, Bingyu Zhang, Runji Xiong, Mi Liu, Jin Li, Yanan Li, Runming Jin, Huyong Zheng

Blood (2025) 146 (Supplement 1): 3444.

https://doi.org/10.1182/blood-2025-3444

Published: 2025

Journal Articles

In Vivo and Ex Vivo Expansion of Functional Human Repopulating Cells through JARID2 Inhibition

Wentao Han, Hassan Bjeije, Hamza Celik, Michael P. Rettig, Yanan Li, Andrew L Young, Christine RC Zhang, Infencia Xavier Raj, Saranajith Dunuwille, Grant A Challen

Blood (2024) 144 (Supplement 1): 3398.

https://doi.org/10.1182/blood-2024-211397

Published: 2024

Journal Articles

Fetal Differentiation Programs Afford a Protective Barrier to NUP98 Fusion-Driven AML That Dissipates Shortly after Birth

Jihye Yoon, Elisabeth Denby, Wei Yang, Emily B. Casey, Riddhi M. Patel, Yanan Li, J. Michael White, Luis Batista, Jeffrey A. Magee

Blood (2024) 144 (Supplement 1): 630.

https://doi.org/10.1182/blood-2024-194913

Published: 2024

Journal Articles

EZH2-Mediated Methylation Regulates JARID2 Protein Stability in Normal and Neoplastic Hematopoiesis

Hassan Bjeije, Wentao Han, Hamza Celik, Yanan Li, Michael P. Rettig, Andrew L Young, Saranajith Dunuwille, Nancy Issa, Wei Yang, Jeffrey A. Magee, Grant A Challen

Blood (2024) 144 (Supplement 1): 628.

https://doi.org/10.1182/blood-2024-202827

Published: 2024

Journal Articles

NUP98 -Rearranged Acute Myeloid Leukemia Stem Cells Superimpose Type I Interferon Signaling with Canonical Self-Renewal Programs

Yanan Li, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jeffrey Magee

Blood (2023) 142 (Supplement 1): 4125.

https://doi.org/10.1182/blood-2023-182032

Published: 2023

Journal Articles

Understanding the Functional Differences between PRC2.1 and PRC2.2 in Hematopoiesis

Hassan Bjeije, Nancy Issa, Wentao Han, Yanan Li, Wei Yang, Jeffrey Magee, Grant A Challen

Blood (2023) 142 (Supplement 1): 1311.

https://doi.org/10.1182/blood-2023-184884

Published: 2023

Journal Articles

FLT3 ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation

Yanan Li, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jonny Mendoza-Castrejon, Priscilla Rodriguez-Lopez, Jeffrey A. Magee

Blood (2023) 141 (12): 1442–1456.

https://doi.org/10.1182/blood.2022016889

Published: 2023

Includes: Supplemental data

Journal Articles

FLT3 -ITD Drives Context-Specific Changes in Cell Identity and Variable Interferon Dependence during AML Initiation

Yanan LI, Wei Yang, Riddhi M Patel, Emily B Casey, Elisabeth Denby, Jonny Mendoza-Castrejon, Priscilla Rodriguez-Lopez, Jeffrey A. Magee

Blood (2022) 140 (Supplement 1): 5848–5849.

https://doi.org/10.1182/blood-2022-168043

Published: 2022

Journal Articles

BCLAF1 Regulates Expression of AP-1 Genes and Fetal Hematopoietic Stem Cell Repopulation Activity

Stephanie J. Crowley, Jeffrey J. Bednarski, Jeffrey A. Magee, Yanan LI, Lynn S. White, Wei Yang

Blood (2022) 140 (Supplement 1): 2852–2853.

https://doi.org/10.1182/blood-2022-162867

Published: 2022

Journal Articles

Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice

Sourav Bhattacharya, Rachel A. Idol, Wei Yang, Jorge David Rojas Márquez, Yanan Li, Guangming Huang, Wandy L. Beatty, Jeffrey J. Atkinson, John H. Brumell, Juhi Bagaitkar, Jeffrey A. Magee, Mary C. Dinauer

Blood (2022) 139 (19): 2855–2870.

https://doi.org/10.1182/blood.2021015365

Published: 2022

Includes: Supplemental data

Journal Articles

Preliminary Results of Zanubrutinib-Containing Regimens in DLBCL and Cerebrospinal Fluid Distribution of Zanubrutinib

Yan Zhang, Yanan Li, Zhe Zhuang, Wei Wang, Chong Wei, Danqing Zhao, Jian Li, Daobin Zhou

Blood (2021) 138 (Supplement 1): 4556.

https://doi.org/10.1182/blood-2021-150949

Published: 2021

Journal Articles

FLT3 ITD and NUP98 translocations Cooperate to Induce Type I Interferon Signaling That Impedes Hematopoietic Progenitor Differentiation

Yanan LI, Wei Yang, Priscilla Rodriguez-Lopez, Riddhi M Patel, Emily B Casey, Elisabeth Denby, Jeffrey A. Magee

Blood (2021) 138 (Supplement 1): 1150.

https://doi.org/10.1182/blood-2021-151702

Published: 2021

Journal Articles

FLT3 ITD Target Enhancers Are Primed but Inaccessible in Fetal Hematopoietic Progenitors

Yanan Li, PhD, Riddhi M Patel, BS, Emily Casey, Jeffrey A. Magee, MD PhD

Blood (2019) 134 (Supplement_1): 1228.

https://doi.org/10.1182/blood-2019-126201

Published: 2019

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Fetal context conveys heritable protection against MLL-rearranged AML that depends on MLL3

NUP98-rearranged pediatric AML is sustained by a conserved leukemia stem cell program with SPNS2/3 as a targetable vulnerability

Palbociclib combined with venetoclax and azacitidine in NUP98-rearranged pediatric AML: A multicenter phase II trial demonstrating durable remission and survival benefit

In Vivo and Ex Vivo Expansion of Functional Human Repopulating Cells through JARID2 Inhibition

Fetal Differentiation Programs Afford a Protective Barrier to NUP98 Fusion-Driven AML That Dissipates Shortly after Birth

EZH2-Mediated Methylation Regulates JARID2 Protein Stability in Normal and Neoplastic Hematopoiesis

NUP98 -Rearranged Acute Myeloid Leukemia Stem Cells Superimpose Type I Interferon Signaling with Canonical Self-Renewal Programs

Understanding the Functional Differences between PRC2.1 and PRC2.2 in Hematopoiesis

FLT3 ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation

FLT3 -ITD Drives Context-Specific Changes in Cell Identity and Variable Interferon Dependence during AML Initiation

BCLAF1 Regulates Expression of AP-1 Genes and Fetal Hematopoietic Stem Cell Repopulation Activity

Macrophage NOX2 NADPH oxidase maintains alveolar homeostasis in mice

Preliminary Results of Zanubrutinib-Containing Regimens in DLBCL and Cerebrospinal Fluid Distribution of Zanubrutinib

FLT3 ITD and NUP98 translocations Cooperate to Induce Type I Interferon Signaling That Impedes Hematopoietic Progenitor Differentiation

FLT3 ITD Target Enhancers Are Primed but Inaccessible in Fetal Hematopoietic Progenitors

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