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Journal Articles

Proteomic subtypes enrich current acute myeloid leukemia nomenclature and reflect intrinsic pathogenesis alongside aging

Open Access
Wen-Yan Cheng, Xiao Yi, Zhen-Yi Wang, Jian-Feng Li, Jun-Yi Zhang, Rui-Hong Zhang, Qian-Qian Zhang, Xiang-Qin Weng, Ting Huang, Yong-Mei Zhu, Chao Wang, Wei Yin, Jia-Nan Zhang, Hui-Yi Wu, Jun-Min Li, Hong-Ming Zhu, Li Chen, Wen-Fang Wang, Yu-Ting Dai, Chen-Xu Gao, Xuan Liu, Shan Wang, Sheng-Yue Wang, Bo Jiao, Zhu Chen, Hai Fang, Tong Yin, Yang Shen, Sai-Juan Chen
Journal: Blood
Blood (2025) 146 (22): 2681–2695.
https://doi.org/10.1182/blood.2024027692
Published: 2025
Includes: Supplemental data
Journal Articles

Simvastatin targets the cholesterol–bile acid axis to improve ALL survival by remodeling the metabolic microenvironment

Free
Junyu Wang, Bo Jiao, Tuantuan Gui, Xuan Liu, Shan-Shan Guo, Cheng Wang, Weiyang Liu, Li-Jun Peng, Jiayi Ren, Ming Zhang, Yun Tan, Duohui Jing, Jian-Qing Mi, Tong Yin, Hai Fang, Sai-Juan Chen, JIN WANG
Journal: Blood
Blood (2025) 146 (Supplement 1): 3362.
https://doi.org/10.1182/blood-2025-3362
Published: 2025
Journal Articles

Loss of DCAF8 impairs hematopoietic stem cell function with cellular senescence via the DOCK11-CDC42 axis

Open Access
Pengfei Xu, Xiuli Zhang, Donghe Li, Bo Jiao, Jiawei Nie, Yi Huang, Zhizhou Xia, Jiaoyang Li, Yuqing Dan, Xu Huang, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Shiyu Ji, Yong Cang, Ruibao Ren, Ping Liu
Journal: Blood
Blood (2025) 146 (12): 1462–1475.
https://doi.org/10.1182/blood.2024027335
Published: 2025
Includes: Supplemental data
Journal Articles

Transposable elements as novel therapeutic targets for PARPi-induced synthetic lethality in PcG-mutated blood cancer

Open Access
Bernd B. Zeisig, Chiou-Tsun Tsai, Clemence Virely, Tsz Kan Fung, Ali Tuğrul Akin, Estelle Troadec, Bo Jiao, I. Richard Thompson, Priscilla Nga Ieng Lau, Nanjun Li, Andriani Charalambous, Larissa Bomfim, Jennifer Lynch, Athina Georgiou, Robbert Hoogeboom, Claire Lynn, Si-Yi Zhang, Piers E. M. Patten, Cynthia L. Fisher, Anna Schuh, Seishi Ogawa, Ghulam Mufti, Mohammad M. Karimi, Chi Wai Eric So
Journal: Blood
Blood (2025) 146 (11): 1314–1330.
https://doi.org/10.1182/blood.2025028560
Published: 2025
Includes: Supplemental data
Journal Articles

The Endocannabinoid N-Arachidonoyl Dopamine Induces Leukemia Cell Pyroptosis to Overcome the Venetoclax Resistance

Free
Min Wu, Lingyun Tang, Bo Jiao, Ping Liu, Junmin Li, Ruibao Ren
Journal: Blood
Blood (2024) 144 (Supplement 1): 2206.
https://doi.org/10.1182/blood-2024-202040
Published: 2024
Journal Articles

Metabolomic Insights into the Pathogenesis and Prognostic Potential of Adult Acute Lymphoblastic Leukemia

Free
Junyu Wang, Tuantuan Gui, Tong Yin, Yuting Dai, Jing Qiao, Jianfeng Li, Jie Xu, Yuanfang Liu, Yan Wang, Yun Tan, Bo Jiao, Yongmei Zhu, Zhu Chen, Wenlian Chen, Hai Fang, Jian Hou, Jian-Qing Mi, Jin Wang, Sai-Juan Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 2971.
https://doi.org/10.1182/blood-2023-184328
Published: 2023
Journal Articles

Palmitoylation of GNA13 Is Essential for Its Tumor Suppressor Function and Its Inhibition Confers Hypersensitivity of B-Cell Lymphoma to BCL2 Inhibitors

Free
Zhizhou Xia, Xiuli Zhang, Ping Liu, MD PhD, Bo Jiao, PhD, Ruibao Ren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3787.
https://doi.org/10.1182/blood-2019-126368
Published: 2019
Journal Articles

BCR/ABL Can Promote CD19 + Cell Growth but Not Render Them Long-Term Stemness

Free
Donghe Li, MS, Xuemei Zhao, MS, Bo Jiao, PhD, Ping Liu, MD, Ruibao Ren, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2709.
https://doi.org/10.1182/blood.V128.22.2709.2709
Published: 2016
Journal Articles

Roles of Palmitoylation and the KIKK Membrane-Targeting Motif in Leukemogenesis By Oncogenic KRAS4A

Free
Huanbin Zhao, PhDcandidate, Ping Liu, MD, Ruihong Zhang, BS, Min Wu, MD, Donghe Li, BS, Xuemei Zhao, BS, Chun Zhang, MS, Bo Jiao, PhD, Zhu Chen, MD PhD, Ruibao Ren, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1242.
https://doi.org/10.1182/blood.V126.23.1242.1242
Published: 2015
Journal Articles

The Endocannabinoid/Endovanilloid N-Arachidonoyl Dopamine Suppresses the Plasma Membrane Translocation and Neoplastic Transforming Activity of NRAS and KRAS4A

Free
Min Wu, PhDcandidate, Bo Jiao, PhD, Ruibao Ren, MD/PhD
Journal: Blood
Blood (2014) 124 (21): 434.
https://doi.org/10.1182/blood.V124.21.434.434
Published: 2014
Journal Articles

Palmitoyl Acyltransferase DHHC9 Is Required for Efficient Induction of Leukemia By Oncogenic NRAS

Free
Ping Liu, MD/PhD, Bo Jiao, PhD, Ruihong Zhang, B.S., Huanbin Zhao, M.S., Chun Zhang, M.S., Min Wu, M.S., Qingsong Qiu, M.S., Donghe Li, B.S., Xuemei Zhao, B.S., Ruibao Ren, MD/PhD
Journal: Blood
Blood (2014) 124 (21): 893.
https://doi.org/10.1182/blood.V124.21.893.893
Published: 2014
Journal Articles

Cytogenetic and Molecular Features of 1331 Chinese Patients with Primary Acute Lymphoblastic Leukemia (ALL).

Free
Bing Chen, Xiang Wang, Ying Yao, Yong-Mei Zhu, Hai-Yan He, Xiao-Xing Jiang, Ji-Fang Zhou, Hai-Min Chen, Qi Cao, Guang Yang, Chun-Lei Jiang, Xiang-Qin Weng, Xu-Xi Zhang, Bo Jiao, Wei Li Zhao, MD, PhD, Jun-Min Li, Yu Chen, Shu-Min Xiong, Zhi-Xiang Shen, MD, Long-Jun Gu, MD, Hui Jiang, Jian-Qing Mi, Zhu Chen, Sai-Juan Chen, PhD
Journal: Blood
Blood (2009) 114 (22): 4718.
https://doi.org/10.1182/blood.V114.22.4718.4718
Published: 2009
Journal Articles

AML1-ETO9a Correlated with C-KIT Overexpression/Mutation and Indicated Poor Disease Outcome in t(8;21) Acute Myeloid Leukemia.

Free
Yang Liang, Bo Jiao, Chuan-Feng Wu, Shu-Min Xiong, Long-Jun Gu, Zhu Chen, Sai-Juan Chen
Journal: Blood
Blood (2007) 110 (11): 1822.
https://doi.org/10.1182/blood.V110.11.1822.1822
Published: 2007