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Journal Articles

The Expression of BTG1 in De Novo AML Patients Regulated By Demethylation of Decitabine and Its Evaluation in the Deep Remission of Patients

Shiyuan Zhang, Mengyuan Li, Xiaojian Zhu, Hao Zhou, Bin Xu, Xiwen Tong, Su Shuai, Yi Zhu, Yi Xiao, Liang Huang, Dengju Li, Wei Huang, Jia Wei, Mei Huang, Donghua Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1401.
https://doi.org/10.1182/blood-2024-205864
Published: 2024
Journal Articles

Phase 1/2 Study of Polatuzumab in Combination with Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR-P) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma: Preliminary Safety, Efficacy, and Molecular Analysis

Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, James D. Phelan, Jagan R. Muppidi, Max J Gordon, Yandan Yang, Weihong Xu, Theresa Davies-Hill, Da Wei Huang, Craig J. Thomas, Michele Ceribelli, Frances A Tosto, Anna M Juanitez, Amynah Pradhan, Candis Morrison, Atekelt Tadese, Allison P. Jacob, Heidi Simmons, Seth M. Steinberg, Elaine S. Jaffe, Mark Roschewski, Louis M. Staudt, Wyndham H Wilson
Journal: Blood
Blood (2024) 144 (Supplement 1): 1722.
https://doi.org/10.1182/blood-2024-197987
Published: 2024
Journal Articles

Efficacy of Decitabine in Combination with IA Versus IA in Patients with Newly Diagnosed AML, a Multicenter, Prospective, Randomized Controlled Trial

Xiwen Tong, Bin Xu, Shiyuan Zhang, Xiaojian Zhu, Mengyuan Li, Su Shuai, Yi Zhu, Zhenqian Huang, Yaya Wang, Yi Xiao, Liang Huang, Dengju Li, Wei Huang, Jia Wei, Mei Huang, Zhiping Huang, Yuanyan Tang, Hongbo Ren, Donghua Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4276.
https://doi.org/10.1182/blood-2024-205769
Published: 2024
Journal Articles

Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes

Julius C. Enssle, Björn Häupl, Arber Qoku, Boya Wang, George W. Wright, Sharon Barrans, Matthew Anthony Care, Cathy Burton, Caitlin Gribbin, Sebastian Scheich, Sebastian Wolf, James D. Phelan, Da Wei Huang, Andrea diFonzo, Martine Pape, Marion Bodach, Dominique Jahn, Uwe Plessmann, Daniel J Hodson, Bernhard Kuster, Roland Schmitz, Henning Urlaub, Reuben Tooze, Giorgio Inghirami, Florian Buettner, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2024) 144 (Supplement 1): 229.
https://doi.org/10.1182/blood-2024-204606
Published: 2024
Journal Articles

Phase 1b/2 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR) in Relapsed/Refractory and Treatment-Naïve Mantle Cell Lymphoma: Preliminary Analysis of Safety, Efficacy, and Minimal Residual Disease

Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, James D. Phelan, Jagan R. Muppidi, Max J Gordon, Yandan Yang, Weihong Xu, Theresa Davies-Hill, Da Wei Huang, Craig J. Thomas, Michele Ceribelli, Frances A Tosto, Anna M Juanitez, Amynah Pradhan, Candis Morrison, Atekelt Tadese, Colleen Ramsower, Lisa M. Rimsza, Allison P. Jacob, Heidi Simmons, Seth M. Steinberg, Elaine S. Jaffe, Mark Roschewski, Louis M. Staudt, Wyndham H Wilson
Journal: Blood
Blood (2024) 144 (Supplement 1): 750.
https://doi.org/10.1182/blood-2024-197956
Published: 2024
Journal Articles

Genetic Subclones Reveal Phenotypic Heterogeneity in Diffuse Large B-Cell Lymphoma

Boya Wang, George W. Wright, Julius C. Enssle, Yandan Yang, Da Wei Huang, Xin Yu, Arvin E Ruiz, James D. Phelan, Arthur L Shaffer, III, Thomas Oellerich, Giorgio Inghirami, Louis M. Staudt
Journal: Blood
Blood (2024) 144 (Supplement 1): 451.
https://doi.org/10.1182/blood-2024-204201
Published: 2024
Journal Articles

Selinexor-Based Chemotherapy-Free or Low-Dose Chemotherapy Regimens in Acute Myeloid Leukemia, Myelodysplastic Syndromes: Efficacy and Safety

Xiwen Tong, Bin Xu, Su Shuai, Yi Zhu, Jin Jie, Yizhou Peng, Li Li, Mengyuan Li, Xia Mao, Wei Huang, Donghua Zhang, Jia Wei
Journal: Blood
Blood (2024) 144 (Supplement 1): 6003.
https://doi.org/10.1182/blood-2024-205493
Published: 2024
Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Molecular Mechanism of Action of Glucocorticoids in Lymphoma Therapy

Jaewoo Choi, Michele Ceribelli, James D Phelan, Björn Häupl, Da Wei Huang, George Wright, Tony Hsiao, Vivian M Morris, Francesco Ciccarese, Boya Wang, Sean R Corcoran, Sebastian Scheich, Xin Yu, Weihong Xu, Yandan Yang, Joyce Zhou, Grace Zhang, Jagan R. Muppidi, Giorgio Inghirami, Thomas Oellerich, Craig J. Thomas, Louis M. Staudt
Journal: Blood
Blood (2023) 142 (Supplement 1): 2986.
https://doi.org/10.1182/blood-2023-174325
Published: 2023
Journal Articles

Phase Ib/II Study of Multi-Targeted Therapy with Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Lenalidomide (ViPOR) in Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Christopher Melani, Rahul Lakhotia, Stefania Pittaluga, James D Phelan, Da Wei Huang, George Wright, Jillian Simard, Jagan R. Muppidi, Craig J. Thomas, Michele Ceribelli, Frances A Tosto, Yandan Yang, Weihong Xu, Theresa Davies-Hill, Svetlana Pack, Cody J Peer, Oluwatobi Arisa, Esther Mena, Maria L. Lindenberg, Ethan Bergvall, Craig A. Portell, Rafic J Farah, Seung Tae Lee, Amynah Pradhan, Candis Morrison, Atekelt Tadese, Anna M Juanitez, Crystal Lu, Allison P. Jacob, Heidi Simmons, William D Figg, Seth M. Steinberg, Elaine S Jaffe, Mark Roschewski, Louis M. Staudt, Wyndham H Wilson
Journal: Blood
Blood (2023) 142 (Supplement 1): 434.
https://doi.org/10.1182/blood-2023-180173
Published: 2023
Journal Articles

Ksd-101 in Patients with EBV-Associated Hematologic Neoplasms: Results from an Ongoing Phase I Clinical Study

Chunrui Li, Di Wang, Atsuhiko Hasegawa, Huining Liu, Ning An, Yuhan Bao, Meijuan Huang, Yi Xiao, Donghua Zhang, Miao Zheng, Wei Huang, Lijun Jiang
Journal: Blood
Blood (2023) 142 (Supplement 1): 4837.
https://doi.org/10.1182/blood-2023-182556
Published: 2023
Journal Articles

Analysis and therapeutic targeting of the IL-1R pathway in anaplastic large cell lymphoma

Zhihui Song, Wenjun Wu, Wei Wei, Wenming Xiao, Michelle Lei, Kathy Q. Cai, Da Wei Huang, Subin Jeong, Jing-Ping Zhang, Hongbo Wang, Marshall E. Kadin, Thomas A. Waldmann, Louis M. Staudt, Masao Nakagawa, Yibin Yang
Journal: Blood
Blood (2023) 142 (15): 1297–1311.
https://doi.org/10.1182/blood.2022019166
Published: 2023
Includes: Supplemental data
Journal Articles

Genome-wide CRISPR screen identifies CDK6 as a therapeutic target in adult T-cell leukemia/lymphoma

Takashi Ishio, Sarvesh Kumar, Joji Shimono, Anusara Daenthanasanmak, Sigrid Dubois, Yuquan Lin, Bonita Bryant, Michael N. Petrus, Emmanuel Bachy, Da Wei Huang, Yandan Yang, Patrick L. Green, Hiroo Hasegawa, Michiyuki Maeda, Hideki Goto, Tomoyuki Endo, Takashi Yokota, Kanako C. Hatanaka, Yutaka Hatanaka, Shinya Tanaka, Yoshihiro Matsuno, Yibin Yang, Satoshi Hashino, Takanori Teshima, Thomas A. Waldmann, Louis M. Staudt, Masao Nakagawa
Journal: Blood
Blood (2022) 139 (10): 1541–1556.
https://doi.org/10.1182/blood.2021012734
Published: 2022
Includes: Supplemental data
Journal Articles

Phase 2 Study of Acalabrutinib Window Prior to Frontline Therapy in Untreated Aggressive B-Cell Lymphoma: Preliminary Results and Correlatives of Response to Acalabrutinib

Mark Roschewski, James D. Phelan, Stefania Pittaluga, Christopher Melani, Rahul Lakhotia, Jacob J. Chabon, Jagan R. Muppidi, Kathryn A. Lurain, Jillian Simard, Amynah Pradhan, Amy Hillsman, Madeline Rilko, Seth M. Steinberg, George W. Wright, Da Wei Huang, Yandan Yang, Michail S. Lionakis, Alexander Bagaev, Ekaterina Postovalova, Mark Meerson, Olga Kudryashova, Nikita Kotlov, Nathan H. Fowler, David M. Kurtz, Ash A. Alizadeh, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson
Journal: Blood
Blood (2021) 138 (Supplement 1): 524.
https://doi.org/10.1182/blood-2021-145228
Published: 2021
Journal Articles

A Phase I/IIa Study of Lemzoparlimab, a Monoclonal Antibody Targeting CD47, in Patients with Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS): Initial Phase I Results

Junyuan Qi, MD, Jian Li, MD, Bin Jiang, MD, Bo Jiang, MD, Hongzhong Liu, MD, Xinxin Cao, MD, Meixiang Zhang, MD, Yuan Meng, MD, Xiaoyu MA, Yingmin Jia, Jiyuan Guo, Yanni Zhang, Wei Huang, Jianxiang Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-134391
Published: 2020
Journal Articles

Integration and Iteration: Using Advanced, High-Content Imaging and Single-Cell Gene Expression Analysis to Uncover Unique Aspects of Follicular Lymphoma Biology

Andrea J. Radtke, PhD, Arthur L. Shaffer, III, PhD, Stefania Pittaluga, MD PhD, Alexander Bagaev, MS, Nishant Thakur, PhD, Theresa Davies-Hill, BS, Olga Plotnikova, MS, Ilia Galkin, MS, Ekaterina Postovalova, PhD, Viktor Svekolkin, MS, Sergei Isaev, MS, Yaroslav Lozinsky, MS, Mark Meerson, MS, Arina Varlamova, MS, Pavel Ovcharov, MS, Margarita Polyakova, MD, Krystle Nomie, PhD, Ekaterina Nuzhdina, MS, Nikita Kotlov, MS, Maria Tsiper, PhD, Felix Frenkel, PhD, Ravshan Attaulakhanov, PhD, Nathan H Fowler, MD, Ziv Yaniv, PhD, Bradley C Lowekamp, PhD, Michael Kelly, PhD, Ezzat Dadkhah, PhD, Da Wei Huang, MD, Jagan R. Muppidi, MD PhD, Elaine S. Jaffe, MD, Wyndham H. Wilson, MD PhD, Louis M. Staudt, MD PhD, Ronald N. Germain, MD PhD, Mark Roschewski, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-142633
Published: 2020
Journal Articles

Microrna-191 Regulates T-Cell Clonal Expansion during Graft-Versus-Host Disease

Chuanfeng Xiong, MD, Wei Huang, MD PhD, Xiaoli Nie, MD PhD, Ying Huang, MD PhD, Yiqun Jiao, MD, Yujing Zou, PhD, Charles Huang, Emilio Feijoo, Dong Pan, PhD, Diana M Cardona, MD, Nelson J. Chao, MD, Qi-jing Li, PhD, Benny J. Chen, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4433.
https://doi.org/10.1182/blood-2019-130179
Published: 2019
Journal Articles

KLHL14 Is a Tumor Suppressor in Diffuse Large B-Cell Lymphoma

Jaewoo Choi, PhD, James D Phelan, PhD, Ryan M. Young, PhD, Thomas Oellerich, MD, Da Wei Huang, MD, Arthur L Shaffer, PhD, Louis Staudt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2766.
https://doi.org/10.1182/blood-2019-125137
Published: 2019
Journal Articles

circMYBL2, a circRNA from MYBL2 , regulates FLT3 translation by recruiting PTBP1 to promote FLT3 -ITD AML progression

Yu-Meng Sun, Wen-Tao Wang, Zhan-Cheng Zeng, Tian-Qi Chen, Cai Han, Qi Pan, Wei Huang, Ke Fang, Lin-Yu Sun, Yan-Fei Zhou, Xue-Qun Luo, Chengwei Luo, Xin Du, Yue-Qin Chen
Journal: Blood
Blood (2019) 134 (18): 1533–1546.
https://doi.org/10.1182/blood.2019000802
Published: 2019
Includes: Supplemental data
Journal Articles

Effective Chimeric Antigen Receptor T Cell Therapy for Relapsed and Refractory Acute Lymphoblastic Leukemia in Children Can be Administered Safely Under the Real-Time Monitoring of Th1/Th2 Cytokine Patterns Measured By the Cytometric Bead Array Technology

Yongmin Tang, MD, Diying Shen, MD, Lei Xiao, PhD, Hua Song, MD, Fenying Zhao, MD, Xiaojun Xu, MD, Weiqun Xu, MD PhD, Di Wang, MD, Juan Liang, MD, Meixin Fang, MD, Chan Liao, MD PhD, Sisi Li, MD PhD, Ning Zhao, MS, Wei Huang, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4030.
https://doi.org/10.1182/blood-2018-99-120007
Published: 2018