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Journal Articles

Proteogenomic Screens Identify Plasma Cell Specific Vulnerabilities to Halt Oncogenic Transcription in Multiple Myeloma

Arnold Bolomsky, Smriti Kanangat, Michele Ceribelli, Kristina Rinaldi, Lin Zhang, Elizabeth Hill, Jagan R. Muppidi, Craig J. Thomas, Ryan M. Young
Journal: Blood
Blood (2024) 144 (Supplement 1): 763.
https://doi.org/10.1182/blood-2024-208485
Published: 2024
Journal Articles

A Phase 2 Response-Adapted Study of Daratumumab, Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple Myeloma

Roshani Patel, Amrit Bhaskarla, Max J Gordon, Michael Emanuel, Dana I. Delgado Colon, Hao-Wei Wang, Constance M. Yuan, Liza Lindenberg, Esther Mena, Baris Turkbey, Nick Micheletti, Laura M Yee, Nisha Patel, Irina Maric, Raul C. Braylan, Katherine R. Calvo, Louis M. Staudt, Ryan M. Young, Mark Roschewski, Dickran Kazandjian, Elizabeth Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 7059.
https://doi.org/10.1182/blood-2024-201563
Published: 2024
Journal Articles

Fixed Duration Combination Therapy with Carfilzomib, Lenalidomide, and Dexamethasone Followed By Lenalidomide Maintenance Leads to High Rates of Sustained MRD Negativity in Patients with High-Risk Smoldering Multiple Myeloma: Long Term Follow up of an Investigator Initiated Phase 2 Trial

Elizabeth Hill, Joseph L. Roswarski, Amrit Bhaskarla, Alexander Dew, Candis Morrison, Michael Emanuel, Ani Petrosyan, Hao-Wei Wang, Constance M. Yuan, Liza Lindenberg, Esther Mena, Baris Turkbey, Nisha Patel, Irina Maric, Alina Dulau-Florea, Katherine Calvo, Raul C. Braylan, Maryalice Stetler-Stevenson, Seth M. Steinberg, William Figg, Ryan M. Young, Ola Landgren, Mark Roschewski, Dickran Kazandjian
Journal: Blood
Blood (2023) 142 (Supplement 1): 337.
https://doi.org/10.1182/blood-2023-181811
Published: 2023
Journal Articles

Exceptional Response to BTK Inhibitors in Aggressive Lymphomas Linked to Chronic Selective Autophagy

James D Phelan, Sebastian Scheich, Jaewoo Choi, George Wright, Björn Häupl, Ryan M. Young, Sara Rieke, Martine Pape, Yanlong Ji, Henning Urlaub, Carmen Doebele, Alena Zindel, Tanja Wotapek, Monica Kasbekar, Da Wei Huang, Zana Coulibaly, Vivian M Morris, Xin Yu, Weihong Xu, Yandan Yang, Hong Zhao, Christopher J. Shoemaker, Zhuo Wang, Arthur Shaffer, Louis M. Staudt, Thomas Oellerich
Journal: Blood
Blood (2023) 142 (Supplement 1): 850.
https://doi.org/10.1182/blood-2023-190851
Published: 2023
Journal Articles

Genomic Profiling to Interpret the Outcomes of Early Intervention for High-Risk Smoldering Myeloma

Benjamin Diamond, Dickran Kazandjian, Marios Papadimitriou, Bachisio Ziccheddu, Patrick Blaney, Monika Chojnacka, Michael Durante, Elizabeth Hill, Romanos Sklavenitis-Pistofidis, Kylee H Maclachlan, Ryan M. Young, Saad Z Usmani, Faith E. Davies, Gad Getz, Irene M. Ghobrial, Gareth J. Morgan, Francesco Maura, Ola Landgren
Journal: Blood
Blood (2023) 142 (Supplement 1): 757.
https://doi.org/10.1182/blood-2023-181817
Published: 2023
Journal Articles

Aberrant expansion of spontaneous splenic germinal centers induced by hallmark genetic lesions of aggressive lymphoma

Grace M. Pindzola, Raud Razzaghi, Rachel N. Tavory, Hang T. Nguyen, Vivian M. Morris, Moyi Li, Shreya Agarwal, Bonnie Huang, Takaharu Okada, Hans C. Reinhardt, Gero Knittel, Hamid Kashkar, Ryan M. Young, Stefania Pittaluga, Jagan R. Muppidi
Journal: Blood
Blood (2022) 140 (10): 1119–1131.
https://doi.org/10.1182/blood.2022015926
Published: 2022
Includes: Supplemental data
Journal Articles

KLHL14 Is a Tumor Suppressor in Diffuse Large B-Cell Lymphoma

Jaewoo Choi, PhD, James D Phelan, PhD, Ryan M. Young, PhD, Thomas Oellerich, MD, Da Wei Huang, MD, Arthur L Shaffer, PhD, Louis Staudt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2766.
https://doi.org/10.1182/blood-2019-125137
Published: 2019
Journal Articles

HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling

Roland Walter, Kuan-Ting Pan, Carmen Doebele, Federico Comoglio, Katarzyna Tomska, Hanibal Bohnenberger, Ryan M. Young, Laura Jacobs, Ulrich Keller, Halvard Bönig, Michael Engelke, Andreas Rosenwald, Henning Urlaub, Louis M. Staudt, Hubert Serve, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2017) 129 (5): 598–608.
https://doi.org/10.1182/blood-2016-06-721423
Published: 2017
Includes: Supplemental data
Journal Articles

TC-PTP is required for the maintenance of MYC -driven B-cell lymphomas

Ryan M. Young, Avital Polsky, Yosef Refaeli
Journal: Blood
Blood (2009) 114 (24): 5016–5023.
https://doi.org/10.1182/blood-2008-12-196709
Published: 2009
Includes: Supplemental data
Journal Articles

Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

Ryan M. Young, Ian R. Hardy, Raedun L. Clarke, Nicolai Lundy, Polly Pine, Brian C. Turner, Terry A. Potter, Yosef Refaeli
Journal: Blood
Blood (2009) 113 (11): 2508–2516.
https://doi.org/10.1182/blood-2008-05-158618
Published: 2009
Includes: Supplemental data