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Journal Articles

Exploiting TCF3-Driven Oncogenic Circuits in Burkitt Lymphoma

Jens Löber, Nazli Serin, Salaheddine Ali, Petra Vockova, Marek Werth, Julia Richter, Marieluise Kirchner, Shashwat Sahay, Hanibal Bohnenberger, Kristyna Kupcova, Rebecca Wurm-Kuczera, Claudia Chapuy, Kirsty Wienand, Kamil Bojarczuk, Viviane Grewe, Jenniffer Günther, Naveed Ishaque, Philipp Ströbel, Philipp Mertins, Ondrej Havranek, Wolfram Klapper, Ulrich Keller, Tomas Etrych, Pavel Klener, Björn Chapuy
Journal: Blood
Blood (2024) 144 (Supplement 1): 230.
https://doi.org/10.1182/blood-2024-209616
Published: 2024
Journal Articles

SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma

Anne C. Wilke, Carmen Doebele, Alena Zindel, Kwang Seok Lee, Sara A. Rieke, Michele Ceribelli, Federico Comoglio, James D. Phelan, James Q. Wang, Yana Pikman, Dominique Jahn, Björn Häupl, Constanze Schneider, Sebastian Scheich, Frances A. Tosto, Hanibal Bohnenberger, Philipp Stauder, Frank Schnütgen, Mikolaj Slabicki, Zana A. Coulibaly, Sebastian Wolf, Kamil Bojarczuk, Björn Chapuy, Christian H. Brandts, Philipp Stroebel, Caroline A. Lewis, Michael Engelke, Xincheng Xu, Hahn Kim, Thanh Hung Dang, Roland Schmitz, Daniel J. Hodson, Kimberly Stegmaier, Henning Urlaub, Hubert Serve, Clemens A. Schmitt, Fernando Kreuz, Gero Knittel, Joshua D. Rabinowitz, Hans Christian Reinhardt, Matthew G. Vander Heiden, Craig Thomas, Louis M. Staudt, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2022) 139 (4): 538–553.
https://doi.org/10.1182/blood.2021012081
Published: 2022
Includes: Supplemental data
Journal Articles

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma

Alexander Jethwa, Mikołaj Słabicki, Jennifer Hüllein, Marius Jentzsch, Vineet Dalal, Sophie Rabe, Lena Wagner, Tatjana Walther, Wolfram Klapper, MMML Network Project, Hanibal Bohnenberger, Mandy Rettel, Junyan Lu, Arne H. Smits, Frank Stein, Mikhail M. Savitski, Wolfgang Huber, Yael Aylon, Moshe Oren, Thorsten Zenz
Journal: Blood
Blood (2018) 131 (25): 2789–2802.
https://doi.org/10.1182/blood-2017-09-806679
Published: 2018
Includes: Supplemental data
Journal Articles

HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling

Roland Walter, Kuan-Ting Pan, Carmen Doebele, Federico Comoglio, Katarzyna Tomska, Hanibal Bohnenberger, Ryan M. Young, Laura Jacobs, Ulrich Keller, Halvard Bönig, Michael Engelke, Andreas Rosenwald, Henning Urlaub, Louis M. Staudt, Hubert Serve, Thorsten Zenz, Thomas Oellerich
Journal: Blood
Blood (2017) 129 (5): 598–608.
https://doi.org/10.1182/blood-2016-06-721423
Published: 2017
Includes: Supplemental data
Journal Articles

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling By Suppression of Mir-146a in Acute Myeloid Leukemia

Sebastian Mohr, Carmen Doebele, PhD, Tobias Berg, MD, Federico Comoglio, PhD, Julia Beck, PhD, Gabriela Alexe, PhD, Jasmin Corso, Hanibal Bohnenberger, MD, Philipp Stroebel, MD, Astrid Wachter, Tim Beissbarth, PhD, Frank Schnuetgen, PhD, Nadine Haetscher, PhD, Stefanie Goellner, PhD, Arefeh Rouhi, PhD, Lars Palmqvist, MD PhD, Michael A Rieger, PhD, Carsten Mueller-Tidow, MD, Florian Kuchenbauer, Ekkehardt Schuetz, MD, Henning Urlaub, PhD, Kimberly Stegmaier, MD, R. Keith Humphries, MD PhD, Hubert Serve, MD, Thomas Oellerich, MD
Journal: Blood
Blood (2016) 128 (22): 1533.
https://doi.org/10.1182/blood.V128.22.1533.1533
Published: 2016
Journal Articles

Phosphoproteomic Profiling of the Signaling Output of FLT3-ITD and Its AC220-Resistant Mutants Reveals Profound Signaling Differences and Differential Responsiveness to Inhibition of Downstream Kinases

Carmen Doebele, Johannes Kovar, Diego Yepes, Silvia Münch, Frank Schnütgen, Hanibal Bohnenberger, Anne Köhler, Henning Urlaub, Hubert Serve, Thomas Oellerich, MD
Journal: Blood
Blood (2015) 126 (23): 2453.
https://doi.org/10.1182/blood.V126.23.2453.2453
Published: 2015
Journal Articles

FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation

Thomas Oellerich, Sebastian Mohr, Jasmin Corso, Julia Beck, Carmen Döbele, Helene Braun, Anjali Cremer, Silvia Münch, Johannes Wicht, Mark F. Oellerich, Gesine Bug, Hanibal Bohnenberger, Christina Perske, Ekkehard Schütz, Henning Urlaub, Hubert Serve
Journal: Blood
Blood (2015) 125 (12): 1936–1947.
https://doi.org/10.1182/blood-2014-06-585216
Published: 2015
Includes: Supplemental data
Journal Articles

STAT5-Regulated miRNA193b Controls Hematopoietic Stem and Progenitor Cell Expansion By Fine Tuning Cytokine Signaling

Nadine Haetscher, Yonatan D Feuermann, PhD, Susanne Wingert, Maike Rehage, PhD, Christian Weiser, Frederic B. Thalheimer, Hanibal Bohnenberger, Timm Schroeder, PhD, Hubert Serve, MD, Thomas Oellerich, Lothar Hennighausen, Michael A. Rieger, PhD
Journal: Blood
Blood (2014) 124 (21): 4326.
https://doi.org/10.1182/blood.V124.21.4326.4326
Published: 2014
Journal Articles

Syk and Btk Transduce Survival and Proliferation-Inducing Signals By Activating Distinct Signaling Pathways and Transcriptional Programs in AML Cells

Thomas Oellerich, Sebastian Mohr, Julia Beck, Hanibal Bohnenberger, Carmen Doebele, Jasmin Corso, Gesine Bug, Ekkehard Schuetz, Henning Urlaub, Hubert Serve, MD
Journal: Blood
Blood (2014) 124 (21): 3594.
https://doi.org/10.1182/blood.V124.21.3594.3594
Published: 2014
Journal Articles

β 2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis

Thomas Oellerich, Mark F. Oellerich, Michael Engelke, Silvia Münch, Sebastian Mohr, Marika Nimz, He-Hsuan Hsiao, Jasmin Corso, Jing Zhang, Hanibal Bohnenberger, Tobias Berg, Michael A. Rieger, Jürgen Wienands, Gesine Bug, Christian Brandts, Henning Urlaub, Hubert Serve
Journal: Blood
Blood (2013) 121 (19): 3889–3899.
https://doi.org/10.1182/blood-2012-09-457887
Published: 2013
Includes: Supplemental data