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Philipp Mertins
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Journal Articles

Failure to Execute Caspase Activation Drives Therapy Resistance in TP53 Mutated AML

Ahmed M Mamdouh, Fang Qi Lim, Yang Mi, Elyse A Olesinski, Yichen Wang, Shaista Shabbir Jasdanwala, Karanpreet Singh Bhatia, Xiao Xian Lin, Valeriia Sapozhnikova, Philipp Mertins, Brandon D. Brown, Yihua Qiu, Anthony G. Letai, Alexandre Puissant, Steven M. Kornblau, Jan Krönke, Edward Ayoub, Koji Itahana, Michael Andreeff, Shruti Bhatt
Journal: Blood
Blood (2024) 144 (Supplement 1): 53.
https://doi.org/10.1182/blood-2024-211997
Published: 2024
Journal Articles

Exploiting TCF3-Driven Oncogenic Circuits in Burkitt Lymphoma

Jens Löber, Nazli Serin, Salaheddine Ali, Petra Vockova, Marek Werth, Julia Richter, Marieluise Kirchner, Shashwat Sahay, Hanibal Bohnenberger, Kristyna Kupcova, Rebecca Wurm-Kuczera, Claudia Chapuy, Kirsty Wienand, Kamil Bojarczuk, Viviane Grewe, Jenniffer Günther, Naveed Ishaque, Philipp Ströbel, Philipp Mertins, Ondrej Havranek, Wolfram Klapper, Ulrich Keller, Tomas Etrych, Pavel Klener, Björn Chapuy
Journal: Blood
Blood (2024) 144 (Supplement 1): 230.
https://doi.org/10.1182/blood-2024-209616
Published: 2024
Journal Articles

Quantitative Proteomic Analysis of Relapsed Multiple Myeloma Identifies CDK6 Upregulation As a Potential Targetable Resistance Mechanism for Lenalidomide

Yuen Lam Dora Ng, Stephan Bohl, Evelyn Ramberger, Oliver Popp, Imke Bauhuf, Anna Dolnik, Christian Steinebach, Michael Gütschow, Lars Bullinger, Philipp Mertins, Jan Kroenke
Journal: Blood
Blood (2019) 134 (Supplement_1): 2567.
https://doi.org/10.1182/blood-2019-130682
Published: 2019
Journal Articles

PPM1D -truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells

Josephine D. Kahn, Peter G. Miller, Alexander J. Silver, Rob S. Sellar, Shruti Bhatt, Christopher Gibson, Marie McConkey, Dylan Adams, Brenton Mar, Philipp Mertins, Shaunt Fereshetian, Karsten Krug, Haoling Zhu, Anthony Letai, Steven A. Carr, John Doench, Siddhartha Jaiswal, Benjamin L. Ebert
Journal: Blood
Blood (2018) 132 (11): 1095–1105.
https://doi.org/10.1182/blood-2018-05-850339
Published: 2018
Includes: Supplemental data
Journal Articles

PPM1D Truncating Mutations Confer Chemotherapy Resistance in Hematopoietic Stem Cells, Which Is Reversible By PPM1D Inhibition

Josephine Kahn, MD, Alexander J. Silver, B.S., Philipp Mertins, PhD, Steven Carr, PhD, Siddhartha Jaiswal, MD PhD, Benjamin L. Ebert, MD PhD
Journal: Blood
Blood (2016) 128 (22): 740.
https://doi.org/10.1182/blood.V128.22.740.740
Published: 2016