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Journal Articles

Cancer Pathway Connectivity Resolved By Drug Perturbation and RNA Sequencing

Thi Huong Lan Do, Caroline Lohoff, Ferris Jung, Sandra Kummer, Vladimir Benes, Wolfgang Huber, Junyan Lu, Thorsten Zenz

Blood (2024) 144 (Supplement 1): 3584.

https://doi.org/10.1182/blood-2024-201366

Published: 2024

Journal Articles

Unraveling Molecular Subgroup-Specific Pathway Dependencies in Chronic Lymphocytic Leukemia through Drug-Perturbed Transcriptomic Profiling and Statistical Modeling

Caroline Lohoff, Thi Huong Lan Do, Ferris Jung, Sandra Kummer, Vladimir Benes, Wolfgang Huber, Thorsten Zenz, Junyan Lu

Blood (2024) 144 (Supplement 1): 276.

https://doi.org/10.1182/blood-2024-210844

Published: 2024

Journal Articles

Immune Cell Infiltration Impacts Chemotherapy Efficacy in B-NHL

Peter-Martin Bruch, Christina Schniederjohann, Harald Voehringer, Matthias Meyer-Bender, Sarah Koziel, Lisa-Maria Held, Erin Kim Chung, Hilka Rauert-Wunderlich, Marita Ziepert, Norbert Gattermann, Gerhard Held, German Ott, Andreas Rosenwald, Wolfgang Huber, Sascha Dietrich

Blood (2024) 144 (Supplement 1): 4383.

https://doi.org/10.1182/blood-2024-209562

Published: 2024

Journal Articles

Dissecting the Single Cell Landscape of Leukemic Mantle Cell Lymphoma

Tobias Wertheimer, Hosna Baniadam, Stefanie Reisenauer, Marcel Pohly, Lukas Rindlisbacher, Minqi Lin, Stefanie Kreutmair, Susanne Unger, Jarno Kivioja, Andreas Moor, Burkhard Becher, Wolfgang Huber, Thorsten Zenz

Blood (2023) 142 (Supplement 1): 180.

https://doi.org/10.1182/blood-2023-185576

Published: 2023

Journal Articles

The Gene Expression Landscape of BTK Inhibitor Treatment in Chronic Lymphocytic Leukemia Exposed By Shallow Depth RNA Sequencing

Thi Huong Lan Do, Caroline Lohoff, Ferris Jung, Vladimir Benes, Wolfgang Huber, Junyan Lu, Thorsten Zenz

Blood (2023) 142 (Supplement 1): 4633.

https://doi.org/10.1182/blood-2023-178562

Published: 2023

Journal Articles

Deciphering the Dynamics of the B-NHL Single-Cell Landscape during BTK Inhibition

Hosna Baniadam, Tobias Wertheimer, Stefanie Reisenauer, Odit Gutwein, Thi Huong Lan Do, Marcel Pohly, Ester Cannizzaro, Lukas Rindlisbacher, Stefanie Kreutmair, Susanne Unger, Can Ulutekin, Marijne Vermeer, Colin Sparano, Andreas Moor, Wolfgang Huber, Burkhard Becher, Thorsten Zenz

Blood (2023) 142 (Supplement 1): 3007.

https://doi.org/10.1182/blood-2023-189735

Published: 2023

Journal Articles

Spatial Dissection of the Bone Marrow Microenvironment in Multiple Myeloma By High Dimensional Multiplex Tissue Imaging

Blood (2023) 142 (Supplement 1): 85.

https://doi.org/10.1182/blood-2023-189255

Published: 2023

Journal Articles

Functional Anti-Apoptotic Protein Dependence and Its Relation to Genomic Prognostic Markers and Response to Treatment in Chronic Lymphocytic Leukemia

Stephen Jun Fei Chong, Junyan Lu, Rebecca Valentin, Timothy Z. Lehmberg, Mary C Collins, Charles Herbaux, Carsten Utoft Niemann, Wolfgang Huber, Thorsten Zenz, Matthew S. Davids

Blood (2022) 140 (Supplement 1): 4119–4120.

https://doi.org/10.1182/blood-2022-165936

Published: 2022

Journal Articles

Single-Cell Multi-Omic and Spatial Analysis of Nodal B Cell Non-Hodgkin Lymphomas Reveals Plasticity in B Cell Maturation As a Driver of Intratumor Heterogeneity

Donnacha Fitzgerald, Tobias Roider, Marc-A. Baertsch, Harald Vöhringer, Mareike Knoll, Bettina Budeus, Artur Kibler, Anna Mathioudaki, Léandra Caillé, Linsha Li, Johannes Mammen, Marc Seifert, Wolfgang Huber, Sascha Dietrich

Blood (2022) 140 (Supplement 1): 752–753.

https://doi.org/10.1182/blood-2022-156210

Published: 2022

Journal Articles

A Comprehensive DNA Methylome Analysis of Stereotyped and Non-Stereotyped CLL Reveals an Epigenetic Signature with Strong Clinical Impact Encompassing IGHV Status, Stereotypes and IGLV3-21 R110

Blood (2022) 140 (Supplement 1): 1800–1802.

https://doi.org/10.1182/blood-2022-165181

Published: 2022

Journal Articles

The protein landscape of chronic lymphocytic leukemia

Blood (2021) 138 (24): 2514–2525.

https://doi.org/10.1182/blood.2020009741

Published: 2021

Includes: Supplemental data

Journal Articles

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

Blood (2020) 136 (Supplement 1): 10–11.

https://doi.org/10.1182/blood-2020-137528

Published: 2020

Journal Articles

The U1 Spliceosomal RNA: A Novel Non-Coding Hotspot Driver Mutation Independently Associated with Clinical Outcome in Chronic Lymphocytic Leukemia

Blood (2019) 134 (Supplement_1): 847.

https://doi.org/10.1182/blood-2019-130052

Published: 2019

Journal Articles

Transcriptional Profiling Reveals Strong Impact of Major Molecular Disease Subgroups and Mixed Epistasis in Chronic Lymphocytic Leukemia

Thorsten Zenz, MD, Almut Luetge, Junyan Lu, PhD, Huellein Jennifer, PhD, Sascha Dietrich, MD, Leopold Sellner, MD, Wolfgang Huber, PhD

Blood (2019) 134 (Supplement_1): 1742.

https://doi.org/10.1182/blood-2019-126388

Published: 2019

Journal Articles

Ex-Vivo Drug Response Profiling for Tailoring Treatment in Hematologic Malignancies: The Prospective Non-Interventional SMART-Trial

Nora Liebers, Peter-Martin Bruch, Agnes Gambietz, Holly Giles, BA, Junyan Lu, PhD, Mareike Knoll, Carolin Kolb, Peter Dreger, Carsten Mueller-Tidow, MD, Wolfgang Huber, PhD, Axel Benner, Thorsten Zenz, MD, Sascha Dietrich, MD

Blood (2019) 134 (Supplement_1): 376.

https://doi.org/10.1182/blood-2019-125324

Published: 2019

Journal Articles

Systematic Investigation of Microenvironmental Drug Resistance Mechanisms in Chronic Lymphocytic Leukemia

Peter-Martin Bruch, Holly Giles, BA, Carolin Kolb, Sophie Rabe, MSc, Tobias Roider, MD, Mareike Knoll, Mark Kriegsmann, MD, Katharina Kriegsmann, MD, Christiane Zgorzelski, Sebastian Scheinost, Lena Wagner, Carsten Müller-Tidow, MD, Thorsten Zenz, MD, Wolfgang Huber, PhD, Sascha Dietrich, MD

Blood (2019) 134 (Supplement_1): 3363.

https://doi.org/10.1182/blood-2019-128392

Published: 2019

Journal Articles

The Influence of the Bone Marrow Niche on Drug Response Phenotypes of Blood Cancers

Sophie Rabe, MSc, Eva Schitter, Tobias Roider, Peter-Martin Bruch, Carolin Kolb, Marta Stolarczyk, Jennifer Hüllein, Junyan Lu, Christof von Kalle, Christoph Lutz, Peter Dreger, Carsten Mueller-Tidow, Thorsten Zenz, MD, Wolfgang Huber, Sascha Dietrich, MD

Blood (2018) 132 (Supplement 1): 262.

https://doi.org/10.1182/blood-2018-99-116053

Published: 2018

Journal Articles

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma

Blood (2018) 131 (25): 2789–2802.

https://doi.org/10.1182/blood-2017-09-806679

Published: 2018

Includes: Supplemental data

Journal Articles

Asymptomatic Multiple Myeloma - Background of Progression, Evolution, and Prognosis

Blood (2016) 128 (22): 235.

https://doi.org/10.1182/blood.V128.22.235.235

Published: 2016

Journal Articles

Subgroups of T-Cell Prolymphocytic Leukemia (T-PLL) Discovered By High-Throughput Ex Vivo Drug Testing and Genetic Profiling

Emma I Andersson, MSc, Shady Adnan, MD MSc, Leopold Sellner, MD, Dorine Bellanger, Alexandra Schrader, Giuliano Crispatzu, Henan Zhang, MD, Carlos C Mateos, PhD, Edgar Faber, MD PhD, Steffen Koschmieder, MD, Tim H. Brummendorf, MD PhD, Krister Wennerberg, PhD, Wei Ding, MD PhD, Marc-Henri Stern, MD PhD, Marco Herling, MD, Simon Anders, PhD, Wolfgang Huber, PhD, Thorsten Zenz, MD, Satu Mustjoki, MD, PhD

Blood (2015) 126 (23): 315.

https://doi.org/10.1182/blood.V126.23.315.315

Published: 2015

NARROW

Cancer Pathway Connectivity Resolved By Drug Perturbation and RNA Sequencing

Unraveling Molecular Subgroup-Specific Pathway Dependencies in Chronic Lymphocytic Leukemia through Drug-Perturbed Transcriptomic Profiling and Statistical Modeling

Immune Cell Infiltration Impacts Chemotherapy Efficacy in B-NHL

Dissecting the Single Cell Landscape of Leukemic Mantle Cell Lymphoma

The Gene Expression Landscape of BTK Inhibitor Treatment in Chronic Lymphocytic Leukemia Exposed By Shallow Depth RNA Sequencing

Deciphering the Dynamics of the B-NHL Single-Cell Landscape during BTK Inhibition

Spatial Dissection of the Bone Marrow Microenvironment in Multiple Myeloma By High Dimensional Multiplex Tissue Imaging

Functional Anti-Apoptotic Protein Dependence and Its Relation to Genomic Prognostic Markers and Response to Treatment in Chronic Lymphocytic Leukemia

Single-Cell Multi-Omic and Spatial Analysis of Nodal B Cell Non-Hodgkin Lymphomas Reveals Plasticity in B Cell Maturation As a Driver of Intratumor Heterogeneity

A Comprehensive DNA Methylome Analysis of Stereotyped and Non-Stereotyped CLL Reveals an Epigenetic Signature with Strong Clinical Impact Encompassing IGHV Status, Stereotypes and IGLV3-21 R110

The protein landscape of chronic lymphocytic leukemia

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

The U1 Spliceosomal RNA: A Novel Non-Coding Hotspot Driver Mutation Independently Associated with Clinical Outcome in Chronic Lymphocytic Leukemia

Transcriptional Profiling Reveals Strong Impact of Major Molecular Disease Subgroups and Mixed Epistasis in Chronic Lymphocytic Leukemia

Ex-Vivo Drug Response Profiling for Tailoring Treatment in Hematologic Malignancies: The Prospective Non-Interventional SMART-Trial

Systematic Investigation of Microenvironmental Drug Resistance Mechanisms in Chronic Lymphocytic Leukemia

The Influence of the Bone Marrow Niche on Drug Response Phenotypes of Blood Cancers

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma

Asymptomatic Multiple Myeloma - Background of Progression, Evolution, and Prognosis

Subgroups of T-Cell Prolymphocytic Leukemia (T-PLL) Discovered By High-Throughput Ex Vivo Drug Testing and Genetic Profiling

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American Society of Hematology

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ASH Publications

American Society of Hematology

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