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Hartmut Goldschmidt
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Journal Articles

Talquetamab plus daratumumab for the treatment of relapsed or refractory multiple myeloma in the TRIMM-2 study

Available to Purchase
Clinical Trials & Observations
Ajai Chari, Niels W. C. J. van de Donk, Bhagirathbhai Dholaria, Katja Weisel, María-Victoria Mateos, Hartmut Goldschmidt, Thomas G. Martin, Daniel Morillo, Donna Reece, Paula Rodríguez-Otero, Manisha Bhutani, Anita D’Souza, Albert Oriol, Laura Rosiñol, Nizar J. Bahlis, Deeksha Vishwamitra, Sheri Skerget, Raluca I. Verona, Kalpana Bakshi, Lijuan Kang, Thomas J. Prior, Lien Vandenberk, Jaszianne Tolbert, Sangmin Lee, M. Damiette Smit, Ralph Wäsch
Journal: Blood
Blood (2025) 146 (24): 2902–2913.
https://doi.org/10.1182/blood.2025029360
Published: 2025
Includes: Supplemental data
Journal Articles

Feasibility and efficacy of daratumumab-vcd in transplant-ineligible elderly patients with newly diagnosed multiple myeloma: First results from the multicenter GMMG-dada study

Free
Christof Scheid, Christina Thielen, Sandra Willms, Axel Benner, Kaya Miah, Mathias Hänel, Peter Staib, Britta Besemer, Yon-Dschun Ko, Martin Schmidt-Hieber, Florian Kaiser, Timon Hansen, Maika Klaiber-Hakimi, Sebastian Theurich, Swen Wessendorf, Neise Michael, Christian Schmitt, Ullrich Graeven, Manfred Hensel, Cyrus Khandanpour, Joanna Millo, Stefanie Huhn, Michael Hundemer, Niels Weinhold, Marc Raab, Hartmut Goldschmidt, Tim Richardson
Journal: Blood
Blood (2025) 146 (Supplement 1): 4050.
https://doi.org/10.1182/blood-2025-4050
Published: 2025
Journal Articles

Peripheral residual disease activity assessment by MALDI-TOF mass spectrometry in patients with newly-diagnosed multiple myeloma in the GMMG-HD7 study

Free
Jia xiang Jin, Varun Ginde, Stefanie Huhn, Philipp Reichert, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Thorsten Peters-Regehr, Christof Scheid, Igor Wolfgang Blau, Carsten Mueller-Tidow, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Müller, Evgenii Shumilov, Wolfgang Knauf, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Niels Weinhold, Martin Hoffmann, Axel Benner, Peter Findeisen, Katja Weisel, Hans Salwender, Elias K. Mai, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 920.
https://doi.org/10.1182/blood-2025-920
Published: 2025
Journal Articles

A comparison between subcutaneous isa-vrd from the isasocut study and intravenous isa-vrd from the imroz study in patients with transplant- ineligible newly diagnosed multiple myeloma

Free
Arthur Bobin, Mohamad Mohty, Philippe Moreau, Hartmut Goldschmidt, Meletios Dimopoulos, Robert Orlowski, Cyrille Touzeau, Aurore Perrot, Thomas Chalopin, Mamoun Dib, Lydia Montes, Umer Khan, Mony Morisse, Rick Zhang, Corina Oprea, Florence Suzan Teisserenc, Thierry Facon, Xavier Leleu
Journal: Blood
Blood (2025) 146 (Supplement 1): 7566.
https://doi.org/10.1182/blood-2025-7566
Published: 2025
Journal Articles

Phylogenetic reconstruction reveals early divergence and late expansion of focal lesions in multiple myeloma

Free
Alexandra Poos, Lukas John, Kylee Maclachlan, Marc-Andrea Baertsch, Nina Prokoph, Juan-Jose Garces, Nina Hildenbrand, Christoph Rehnitz, Jan Frenking, Elias K. Mai, Philipp Reichert, Stefanie Huhn, Alexander Brobeil, Carsten Mueller-Tidow, Hartmut Goldschmidt, Saad Usmani, Sandra Sauer, Leo Rasche, Marc Raab, Francesco Maura, Niels Weinhold
Journal: Blood
Blood (2025) 146 (Supplement 1): 685.
https://doi.org/10.1182/blood-2025-685
Published: 2025
Journal Articles

T cell fitness and tumor specificity predict immunotherapy response in multiple myeloma

Free
Niklas Kehl, Simon Steiger, Tim Wagner, Tamara Boschert, Michael Kilian, Carsten Mueller-Tidow, Niels Weinhold, Hartmut Goldschmidt, Karsten Rippe, Marc Raab, Michael Platten, Stefan Eichmueller, Mirco Friedrich
Journal: Blood
Blood (2025) 146 (Supplement 1): 1029.
https://doi.org/10.1182/blood-2025-1029
Published: 2025
Journal Articles

Reprogrammed regulatory T cells as cytotoxic effectors drive anti-tumor immunity under bispecific T cell engager therapy

Free
Julius Michel, Jan Frenking, Anna Metzler, Erin Meermeier, Antonia Schach, Vera Thiel, Tim Wagner, Niklas Kehl, Stefanie Huhn, Alexander Brobeil, Carsten Müller-Tidow, P. Leif Bergsagel, Hartmut Goldschmidt, Hermann Einsele, Leo Rasche, Marta Chesi, Marc Raab, Niels Weinhold, Mirco Friedrich
Journal: Blood
Blood (2025) 146 (Supplement 1): 3951.
https://doi.org/10.1182/blood-2025-3951
Published: 2025
Journal Articles

Daratumumab monotherapy versus active monitoring in patients with high-risk smoldering multiple myeloma: Aquila outcomes based on mayo 2018/IMWG 2020 risk stratification, IMWG 2020 plus cytogenetic criteria, and age

Free
Peter Voorhees, Meletios Dimopoulos, Yaël Cohen, Fredrik Schjesvold, Vania Hungria, Irwindeep Sandhu, Jindriska Lindsay, Ross Baker, Kenshi Suzuki, Hiroshi Kosugi, Mark-David Levin, Meral Beksac, Keith Stockerl-Goldstein, Hila Magen, Albert Oriol, Gabor Mikala, Gonzalo Garate, Koen Theunissen, Ivan Špička, Anne Mylin, Simon Hallam, Sara Bringhen, Katarina Uttervall, Bartosz Pula, Abdullah Khan, Eva Medvedova, J Christine Ye, Andrew Cowan, Philippe Moreau, María-Victoria Mateos, Hartmut Goldschmidt, Diego Vieyra, Ashta Raval, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, S. Vincent Rajkumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 372.
https://doi.org/10.1182/blood-2025-372
Published: 2025
Journal Articles

Health-related quality of life (HRQoL) in patients with newly diagnosed multiple myeloma (NDMM) eligible for transplantation and treated with isatuximab, lenalidomide, bortezomib, and dexamethasone (Isa-RVd) versus rvd alone: Results from part 1 of the GMMG-HD7 study

Free
Elias K. Mai, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Martin Hoffmann, Erin Comerford, Maeva Kyheng, Feng Lin, Stephanie Rhoten, Tatiana Lavrova, Hans Salwender, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 2263.
https://doi.org/10.1182/blood-2025-2263
Published: 2025
Journal Articles

Salvage autologous transplant in relapsed multiple myeloma: long-term follow-up of the phase 3 GMMG ReLApsE trial

Open Access
Clinical Trials & Observations Brief Report
Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias Karl Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Haenel, Ivana von Metzler, Hans W. Lindemann, Christof Scheid, Igor-Wolfgang Blau, Hans J. Salwender, Richard Noppeney, Britta Besemer, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 145 (16): 1780–1787.
https://doi.org/10.1182/blood.2024027342
Published: 2025
Includes: Supplemental data
Journal Articles

Efficacy and safety of daratumumab in intermediate/high-risk smoldering multiple myeloma: final analysis of CENTAURUS

Available to Purchase
Clinical Trials & Observations
Ola Landgren, Ajai Chari, Yael C. Cohen, Andrew Spencer, Peter M. Voorhees, Irwindeep Sandhu, Matthew W. Jenner, Dean Smith, Michele Cavo, Niels W. C. J. van de Donk, Meral Beksac, Philippe Moreau, Hartmut Goldschmidt, Diego Vieyra, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, Craig C. Hofmeister
Journal: Blood
Blood (2025) 145 (15): 1658–1669.
https://doi.org/10.1182/blood.2024025897
Published: 2025
Includes: Supplemental data
Journal Articles

Health-Related Quality of Life (HRQoL) in Patients with Newly Diagnosed Multiple Myeloma (NDMM) Ineligible for Transplantation and Treated with Isatuximab, Bortezomib, Lenalidomide, and Dexamethasone (Isa-VRd) Vs. Vrd Alone: Results from the Imroz Study

Free
Meletios Dimopoulos, Thierry Facon, Meral Beksac, Ludek Pour, Roman Hajek, Zhuogang Liu, Jiri Minarik, Philippe Moreau, Joanna Romejko-Jarosinska, Ivan Špička, Vladimir I. Vorobyev, Britta Besemer, Tadao Ishida, Wojciech Janowski, Sevgi Kalayoglu Besisik, Gurdeep Parmar, Pawel Robak, Elena Zamagni, Hartmut Goldschmidt, Thomas Martin, Salomon Manier, Mohamad Mohty, Robert Z. Orlowski, Erin Comerford, Claire Tian, Jérôme Msihid, Feng Lin, Stephanie Rhoten, Xavier. P Leleu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3352.
https://doi.org/10.1182/blood-2024-207087
Published: 2024
Journal Articles

Long-Term Follow-up Analysis of Progression-Free and Overall Survival in Newly Diagnosed Multiple Myeloma Patients from the GMMG Myeloma Registry Following the Randomized Phase III GMMG-HD6 Trial

Free
Anne-Valérie Keller, Marina Hajiyianni, Eileen Kurre, Elias Karl Mai, Uta Bertsch, Axel Benner, Steffen Luntz, Marc-Steffen Raab, Britta Besemer, Christian Sebastian Michel, Roland Schroers, Roland Fenk, Hans Salwender, Igor Wolfgang Blau, Mathias Hänel, Christoph Mann, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 5140.
https://doi.org/10.1182/blood-2024-194188
Published: 2024
Journal Articles

Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial

Free
Marc S. Raab, Niels Weinhold, K. Martin Kortüm, Jan Krönke, Lilli Podola, Uta Bertsch, Jan H. Frenking, Julia Mersi, Stefanie Huhn, Michael Hundemer, Gunhild Mechtersheimer, Roland Fenk, Katja C. Weisel, Natalie Schub, Florian Bassermann, Monika Engelhardt, Raphael Teipel, Mathias Hänel, Hans Salwender, Bas D Koster, Elena Ershova, Caline Sakabedoyan, Isobel Barrott, Agnes Balogh, Sanjay Vara, Tobias Kampfenkel, Hartmut Goldschmidt, Hermann Einsele, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 493.
https://doi.org/10.1182/blood-2024-206003
Published: 2024
Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Free
Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Development and Validation of Novel Machine Learning-Based Risk Scores for Multiple Myeloma: Insights from the Harmony Alliance Big Data Platform

Free
Adrian Mosquera Orgueira, Marta Sonia Gonzalez Perez, Mattia D'Agostino, David A. Cairns, Alessandra Larocca, Juan José Lahuerta Palacios, Ruth Wester, Uta Bertsch, Anders Waage, Elena Zamagni, Carlos Pérez Míguez, Niels W.C.J. Van De Donk, Graham Jackson, Davide Crucitti, Hans Salwender, Daniele Dall'Olio, Gastone Castellani, Manuel Piñeiro Fiel, Sara Bringhen, Sonja Zweegman, Michele Cavo, Jesus Maria Hernandez Rivas, Benedetto Bruno, Gordon Cook, Martin F Kaiser, Hartmut Goldschmidt, Pieter Sonneveld, Jesús F. San-Miguel, Mario Boccadoro, Maria- Victoria Mateos
Journal: Blood
Blood (2024) 144 (Supplement 1): 2226.
https://doi.org/10.1182/blood-2024-201448
Published: 2024
Journal Articles

MRD By Flow Cytometry and FDG-PET/CT for the Post-Induction Response Assessment in Patients with Multiple Myeloma Treated in the Phase 3 GMMG HD7 Study

Free
Marina Hajiyianni, Christos Sachpekidis, Annette Kopp-Schneider, Elias Karl Mai, Sandra Sauer, Ekaterina Menis, Michael Hundemer, Niels Weinhold, Jens Hillengass, Marc-Steffen Raab, Antonia Dimitrakopoulou-Strauss, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4701.
https://doi.org/10.1182/blood-2024-210171
Published: 2024
Journal Articles

Single Vs. Tandem Autologous Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma: A Real-World Multi-Center Study from the German Registry for Hematopoietic Stem Cell Transplantation and Cell Therapy (DRST)

Free
Nora Grieb, Alexander Oeser, Maximilian Ferle, Franziska Hanke, Sarah Flossdorf, Sandra Sauer, Hartmut Goldschmidt, Carsten Müller-Tidow, Hans Salwender, Roland Fenk, Monika Engelhardt, Robert Zeiser, Vladan Vucinic, Georg-Nikolaus Franke, Igor Wolfgang Blau, Daniel Teschner, Hermann Einsele, Christoph Richard Kimmich, Miriam Kull, Britta Besemer, Nico Gagelmann, Nicolaus Kröger, Thomas Neumuth, Uwe Platzbecker, Maximilian Merz
Journal: Blood
Blood (2024) 144 (Supplement 1): 708.
https://doi.org/10.1182/blood-2024-198638
Published: 2024
Journal Articles

Early Relapse in Patients with Newly-Diagnosed Multiple Myeloma: A European Myeloma Network/Harmony Alliance Analysis Including 10843 Patients

Free
Elias K. Mai, Andrea Manubens, Mattia D'Agostino, David A. Cairns, Alessandra Larocca, Juan José Lahuerta Palacios, Ruth Wester, Uta Bertsch, Anders Waage, Elena Zamagni, María-Victoria Mateos, Daniele Dall'Olio, Niels W.C.J. van de Donk, Graham Jackson, Serena Rocchi, Hans Salwender, Joan Bladé, Bronno van der Holt, Gastone Castellani, Katja C. Weisel, Francesca Gay, Sonja Zweegman, Michele Cavo, Jesus Maria Hernandez Rivas, Benedetto Bruno, Gordon Cook, Martin F Kaiser, Hartmut Goldschmidt, Mario Boccadoro, Jesús F. San-Miguel, Pieter Sonneveld
Journal: Blood
Blood (2024) 144 (Supplement 1): 898.
https://doi.org/10.1182/blood-2024-193310
Published: 2024
Journal Articles

Phase 3 Randomized Study of Daratumumab Monotherapy Versus Active Monitoring in Patients with High-Risk Smoldering Multiple Myeloma: Primary Results of the Aquila Study

Free
Meletios-Athanasios Dimopoulos, Peter M. Voorhees, Fredrik Schjesvold, Yael C. Cohen, Vania Hungria, Irwindeep Sandhu, Jindriska Lindsay, Ross Ian Baker, Kenshi Suzuki, Hiroshi Kosugi, Mark-David Levin, Meral Beksac, Keith Stockerl-Goldstein, Albert Oriol, Gabor Mikala, Gonzalo Martin Garate, Koen Theunissen, Ivan Spicka, Anne K. Mylin, Sara Bringhen, Katarina Uttervall, Bartosz Michal Pula, Eva Medvedova, Andrew J. Cowan, Philippe Moreau, Maria-Victoria Mateos, Hartmut Goldschmidt, Tahamtan Ahmadi, Linlin Sha, Els Rousseau, Liang Li, Robyn M. Dennis, Robin Carson, Vincent Rajkumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 773.
https://doi.org/10.1182/blood-2024-201057
Published: 2024