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Journal Articles

Phase 3 randomized study of teclistamab plus daratumumab versus investigator’s choice of daratumumab and dexamethasone with either pomalidomide or Bortezomib (DPd/DVd) in patients (Pts) with relapsed refractory multiple myeloma (RRMM): Results of majestec-3

Free
María-Victoria Mateos, Nizar Bahlis, Aurore Perrot, Ajay Nooka, Jin Lu, Charlotte Pawlyn, Roberto Mina, Gaston Caeiro, Alain Kentos, Vania Hungria, Donna Reece, Ting Niu, Anne Mylin, Charlotte Hansen, Raphael Teipel, Britta Besemer, Meletios Dimopoulos, Elena Zamagni, Satoshi Yoshihara, Kihyun Kim, Chang-Ki Min, Paulus Geerts, Elena Van Leeuwen-Segarceanu, Agata Tyczynska, Juan Luis Reguera, Magnus Johansson, Markus Hansson, Mehmet Turgut, Mark Grey, Surbhi Sidana, Paula Rodriguez-Otero, Joaquin Martinez-Lopez, Hamza Hashmi, Robin Carson, Rachel Kobos, Weili Sun, Kristen Lantz, Anne Seifert, Debbie Briseno-Toomey, Lisa O'Rourke, Maria Rubin, Diego Vieyra, Lijuan Kang, Luciano Costa
Journal: Blood
Blood (2025) 146 (Supplement 2): LBA-6.
https://doi.org/10.1182/blood-2025-LBA-6
Published: 2025
Journal Articles

Isatuximab subcutaneous by on-body injector in Relapsed/Refractory multiple myeloma in the Phase 3 iraklia study: Effect of body weight on pharmacokinetics and clinical outcome

Free
Jin Lu, Albert Oriol, Alejandro Berkovits, Andrew Spencer, Cesar Gomez, Chunrui Li, Claudio Cerchione, Fei Li, Fredrik Schjesvold, Gurdeep Parmar, Ivan Špička, Marek Hus, Maria del Rosario Custidiano, Meletios Dimopoulos, Peter Rajnics, Sevgi Kalayoglu Besisik, Sikander Ailawadhi, Silvia Ling, Vania Hungria, Xavier Leleu, Florence Suzan Teisserenc, Maya Stefanova-Urena, Rick Zhang, Victorine Koch, Dorothee Semiond
Journal: Blood
Blood (2025) 146 (Supplement 1): 5812.
https://doi.org/10.1182/blood-2025-5812
Published: 2025
Journal Articles

Patient-reported outcomes from dreamm-7 and dreamm-8 using the EQ-5D-3L, patient global impression of severity, and patient global impression of change

Free
Suzanne Trudel, Vania Hungria, María-Victoria Mateos, Chee Paul Lin, Julie Byrne, James Parker, Molly Purser, Sandhya Sapra, Farrah Pompilus, Sumita Roy-Ghanta, Giulia Fulci, Joanna Opalinska, Neal Sule, Brandon Kremer, Meletios Dimopoulos
Journal: Blood
Blood (2025) 146 (Supplement 1): 5823.
https://doi.org/10.1182/blood-2025-5823
Published: 2025
Journal Articles

Functional high-risk Relapsed/Refractory multiple myeloma (RRMM) outcomes with belantamab mafodotin (belamaf): Dreamm-7 and dreamm-8 subgroup analysis

Free
María-Victoria Mateos, Vania Hungria, Meral Beksac, Pawel Robak, Kihyun Kim, Sergei Voloshin, Hanlon Sia, Esther González García, Gracia Martinez, Chang-Ki Min, Marcelo Pitombeira de Lacerda, Anna Sureda Balarí, Ivan Špička, Sosana Delimpasi, Marek Hus, Vera Zherebtsova, Christopher Ward, Phoebe Joy Ho, Roman Hajek, Sebastian Grosicki, Syed Zafar, Al-Ola Abdallah, Jorge Mouro, Zeyad Khalaf, Hena Baig, Ainslee Moore, Chee Paul Lin, Maureen Nichols, Ianire Garrobo-Calleja, Sybil Varghese, Nick Pirooz, Joe Lee, Lydia Eccersley, Elisabet Manasanch, Ludek Pour, Meletios Dimopoulos
Journal: Blood
Blood (2025) 146 (Supplement 1): 5820.
https://doi.org/10.1182/blood-2025-5820
Published: 2025
Journal Articles

Survival impact of anti-CD38-based quadruplet regimens in transplant-ineligible newly diagnosed multiple myeloma: A network meta-analysis and reconstructed individual patient data meta-analysis

Free
Joao Tadeu Damian Souto Filho, Lucas Oliveira Cantadori, Edvan De Queiroz Crusoe, Vania Hungria, Angelo Maiolino
Journal: Blood
Blood (2025) 146 (Supplement 1): 2277.
https://doi.org/10.1182/blood-2025-2277
Published: 2025
Journal Articles

Patients with Relapsed/Refractory multiple myeloma who achieved sustained minimal residual disease negativity in the dreamm-7 trial

Free
María-Victoria Mateos, Pawel Robak, Marek Hus, Vera Zherebtsova, Christopher Ward, Phoebe Joy Ho, Roman Hajek, Kihyun Kim, Sebastian Grosicki, Hanlon Sia, Adam Bryant, Marcelo Pitombeira de Lacerda, Gracia Martinez, Anna Sureda Balarí, Jie Ma, Yinjiao Ma, Maureen Nichols, Jorge Mouro, Zeyad Khalaf, Hena Baig, Benga Kazeem, Nick Pirooz, Sybil Varghese, Joe Lee, Lydia Eccersley, Vania Hungria
Journal: Blood
Blood (2025) 146 (Supplement 1): 2265.
https://doi.org/10.1182/blood-2025-2265
Published: 2025
Journal Articles

Daratumumab monotherapy versus active monitoring in patients with high-risk smoldering multiple myeloma: Aquila outcomes based on mayo 2018/IMWG 2020 risk stratification, IMWG 2020 plus cytogenetic criteria, and age

Free
Peter Voorhees, Meletios Dimopoulos, Yaël Cohen, Fredrik Schjesvold, Vania Hungria, Irwindeep Sandhu, Jindriska Lindsay, Ross Baker, Kenshi Suzuki, Hiroshi Kosugi, Mark-David Levin, Meral Beksac, Keith Stockerl-Goldstein, Hila Magen, Albert Oriol, Gabor Mikala, Gonzalo Garate, Koen Theunissen, Ivan Špička, Anne Mylin, Simon Hallam, Sara Bringhen, Katarina Uttervall, Bartosz Pula, Abdullah Khan, Eva Medvedova, J Christine Ye, Andrew Cowan, Philippe Moreau, María-Victoria Mateos, Hartmut Goldschmidt, Diego Vieyra, Ashta Raval, Linlin Sha, Liang Li, Els Rousseau, Robyn Dennis, Robin Carson, S. Vincent Rajkumar
Journal: Blood
Blood (2025) 146 (Supplement 1): 372.
https://doi.org/10.1182/blood-2025-372
Published: 2025
Journal Articles

Venous thromboembolism in multiple myeloma patients treated with BCMA-directed CAR T-cell therapy: A systematic review and meta-analysis

Free
Pedro Henrique Las Casas, Javier Marco Ayala, Thamiris Silva Soares, Mohammed Baghdadi, Patrick Van Dreden, Eleftheria Lefkou, Prakasha Kempaiah, Laurent Garderet, Vania Hungria, Jawed Fareed, Grigoris Gerotziafas
Journal: Blood
Blood (2025) 146 (Supplement 1): 2687.
https://doi.org/10.1182/blood-2025-2687
Published: 2025
Journal Articles

Long-term responders from the Phase 3 dreamm-7 study of belantamab mafodotin plus bortezomib and dexamethasone vs daratumumab plus bortezomib and dexamethasone in Relapsed/Refractory multiple myeloma

Free
Vania Hungria, Pawel Robak, Marek Hus, Vera Zherebtsova, Christopher Ward, Phoebe Joy Ho, Roman Hajek, Kihyun Kim, Sebastian Grosicki, Hanlon Sia, Adam Bryant, Marcelo Pitombeira de Lacerda, Gracia Martinez, Anna Sureda Balarí, Michał Mielnik, Maureen Nichols, Jorge Mouro, Zeyad Khalaf, Hena Baig, Margaret Polinkovsky, Nick Pirooz, Sybil Varghese, Joe Lee, Lydia Eccersley, María-Victoria Mateos
Journal: Blood
Blood (2025) 146 (Supplement 1): 2262.
https://doi.org/10.1182/blood-2025-2262
Published: 2025
Journal Articles

Impact of belantamab mafodotin–containing regimens on renal function in patients with Relapsed/Refractory multiple myeloma (RRMM) and mild/moderate renal impairment in the dreamm-7 and dreamm-8 trials

Free
Marcelo Pitombeira de Lacerda, Meletios Dimopoulos, Ludek Pour, Kihyun Kim, Sergei Voloshin, Hanlon Sia, Esther González García, Chang-Ki Min, Anna Sureda Balarí, Ivan Špička, Pawel Robak, Marek Hus, Vera Zherebtsova, Merit Hanna, Vinay Jadhav, Jorge Mouro, Zeyad Khalaf, Nick Pirooz, Ianire Garrobo-Calleja, Lydia Eccersley, Elisabet Manasanch, Vania Hungria, Meral Beksac
Journal: Blood
Blood (2025) 146 (Supplement 1): 2260.
https://doi.org/10.1182/blood-2025-2260
Published: 2025
Journal Articles

Efficacy Outcomes By Minimal Residual Disease (MRD) Negativity in Patients with Relapsed or Refractory Multiple Myeloma Treated with Belantamab Mafodotin Plus Bortezomib and Dexamethasone Vs Daratumumab, Bortezomib, and Dexamethasone: Analysis from the Dreamm-7 Trial

Free
Vania Hungria, Marek Hus, Pawel Robak, Vera Zherebtsova, Ana Carolina de Almeida Ribas, Marcelo Pitombeira de Lacerda, Kihyun Kim, Sebastian Grosicki, Irwindeep Sandhu, Christopher Ward, Astrid McKeown, Hena Baig, Jie Ma, Benjamin Lariviere, Benga Kazeem, Lydia Eccersley, Sumita Roy-Ghanta, Joanna Opalinska, Maria Victoria Mateos
Journal: Blood
Blood (2024) 144 (Supplement 1): 3359.
https://doi.org/10.1182/blood-2024-201543
Published: 2024
Journal Articles

Phase 3 Study of Teclistamab (Tec) in Combination with Lenalidomide (Len) and Tec Alone Versus Len Alone in Newly Diagnosed Multiple Myeloma (NDMM) As Maintenance Therapy Following Autologous Stem Cell Transplantation (ASCT): Safety Run-in (SRI) Results from the Majestec-4/EMN30 Trial

Free
Elena Zamagni, Tobias Silzle, Ivan Špička, Sabrin Tahri, Sarah Lonergan, Inger S. Nijhof, Antonietta Pia Falcone, Evangelos Terpos, Jakub Radocha, Roberto Mina, Guldane Cengiz Seval, Meral Beksac, Cesar Rodriguez, Marcelo C. Pasquini, Michel Delforge, Vania Hungria, Donna Reece, Philippe Moreau, Yael C. Cohen, Kihyun Kim, Dominik Dytfeld, Jiří Minařík, Irene Strassl, Jelena Bila, Martin Schreder, Janusz Krawczyk, Fredrik Schjesvold, Caroline Cicin-Sain, Christoph Driessen, Gordon Cook, Lugui Qiu, Gonzalo Martin Garate, Agoston Gyula Szabo, Roman Hájek, Marc S. Raab, Silvia Mangiacavalli, Hermann Einsele, Andrew Spencer, Mario Boccadoro, Helen Vassalou, Lixia Pei, Yingqi Shi, Maria Krevvata, Ryan Gruber, Caline Sakabedoyan, Margaret Cobb, Jagoda Jasielec, Himal Amin, Rachel Kobos, Pieter Sonneveld, Niels W.C.J. van de Donk
Journal: Blood
Blood (2024) 144 (Supplement 1): 494.
https://doi.org/10.1182/blood-2024-205608
Published: 2024
Journal Articles

Use of Teclistamab Outside of Clinical Trials in Latin America: Risk of Infections and Immunoglobulin Replacement

Free
Fernando Vieira Pericole, Edvan Crusoe, Glaciano Ribeiro, Juliana Lima, Erica Lammerhirt Ottoni, Rafael Cunha, Abel Costa, Priscilla Cury, James Maciel, Vania Hungria
Journal: Blood
Blood (2024) 144 (Supplement 1): 7847.
https://doi.org/10.1182/blood-2024-209492
Published: 2024
Journal Articles

Smoldering Multiple Myeloma in Latin America- Risk Stratification

Free
Edvan De Queiroz Crusoe, Alana Von Glasenapp, Glaciano Ribeiro, Leila Perobelli, Paola Ochoa, Fernando Vieira Pericole, Sergio Lopresti, Jayr Schmidt Filho, Cesar Samanez, Guillermina Remaggi, Emanuella Souza, Eloisa Riva, Javiera PAZ Donoso Pineda, Pedro Manoel Marques Garibaldi, Milton A. F. Aranha, Roberto Pessoa Magalhaes Filho, Aline Ramirez Alvarado, Dorotea Beatriz Eugenia Fantl, Kenny Galvez, Dani Laks, Jose Ramiro Espinoza Zamora, Juliana Lima, Rodrigo Ezequiel Vallejo, Camila Peña, Vania Hungria
Journal: Blood
Blood (2024) 144 (Supplement 1): 3774.
https://doi.org/10.1182/blood-2024-209038
Published: 2024
Journal Articles

Daratumumab-Based Quadruplet Versus Triplet Induction Regimens in Frontline Transplant-Eligible Newly Diagnosed Multiple Myeloma: A Systematic Review and Meta-Analysis

Free
Joao Tadeu Damian Souto Filho, Lucas Oliveira Cantadori, Edvan De Queiroz Crusoe, Vania Hungria, Angelo Maiolino
Journal: Blood
Blood (2024) 144 (Supplement 1): 258.
https://doi.org/10.1182/blood-2024-202677
Published: 2024
Journal Articles

Subcutaneous Daratumumab (DARA) + Bortezomib, Cyclophosphamide, and Dexamethasone (VCd) in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis: Overall Survival and Final Major Organ Deterioration Progression-Free Survival Results from the Phase 3 Andromeda Study

Free
Efstathios Kastritis, Giovanni O. Palladini, Monique C. Minnema, Ashutosh D. Wechalekar, Arnaud Jaccard, Hans C. Lee, Vaishali Sanchorawala, Peter Mollee, Jin Lu, Stefan Schönland, Moshe E Gatt, Kenshi Suzuki, Kihyun Kim, M. Teresa Cibeira, Manisha Bhutani, Meral Beksac, Edward Libby, Jason Valent, Vania Hungria, Michael Rosenzweig, Naresh Bumma, Antoine Huart, NamPhuong Tran, Jianping Wang, Yuping Chen, Sandra Y. Vasey, Jordan M. Schecter, Jessica Vermeulen, Raymond L. Comenzo, Giampaolo Merlini
Journal: Blood
Blood (2024) 144 (Supplement 1): 891.
https://doi.org/10.1182/blood-2024-205077
Published: 2024
Journal Articles

Phase 3 Randomized Study of Daratumumab Monotherapy Versus Active Monitoring in Patients with High-Risk Smoldering Multiple Myeloma: Primary Results of the Aquila Study

Free
Meletios-Athanasios Dimopoulos, Peter M. Voorhees, Fredrik Schjesvold, Yael C. Cohen, Vania Hungria, Irwindeep Sandhu, Jindriska Lindsay, Ross Ian Baker, Kenshi Suzuki, Hiroshi Kosugi, Mark-David Levin, Meral Beksac, Keith Stockerl-Goldstein, Albert Oriol, Gabor Mikala, Gonzalo Martin Garate, Koen Theunissen, Ivan Spicka, Anne K. Mylin, Sara Bringhen, Katarina Uttervall, Bartosz Michal Pula, Eva Medvedova, Andrew J. Cowan, Philippe Moreau, Maria-Victoria Mateos, Hartmut Goldschmidt, Tahamtan Ahmadi, Linlin Sha, Els Rousseau, Liang Li, Robyn M. Dennis, Robin Carson, Vincent Rajkumar
Journal: Blood
Blood (2024) 144 (Supplement 1): 773.
https://doi.org/10.1182/blood-2024-201057
Published: 2024
Journal Articles

Belantamab Mafodotin, Bortezomib, and Dexamethasone Vs Daratumumab, Bortezomib, and Dexamethasone in Relapsed/Refractory Multiple Myeloma: Overall Survival Analysis and Updated Efficacy Outcomes of the Phase 3 Dreamm-7 Trial

Free
Vania Hungria, Pawel Robak, Marek Hus, Vera Zherebtsova, Christopher Ward, Phoebe Joy Ho, Roman Hajek, Kihyun Kim, Sebastian Grosicki, Hanlon Sia, Adam Bryant, Marcelo Pitombeira de Lacerda, Gracia Aparecida Martinez, Anna Maria Sureda Balarí, Irwindeep Sandhu, Claudio Cerchione, Peter Ganly, Meletios Dimopoulos, Chengcheng Fu, Mamta Garg, Al-Ola Abdallah, Moshe E Gatt, Albert Oriol, Michele Cavo, Robert Rifkin, Tomoaki Fujisaki, Michał Mielnik, Nick Pirooz, Joe Lee, Astrid McKeown, Rachel Rogers, Hena Baig, Lydia Eccersley, Sumita Roy-Ghanta, Maria Victoria Mateos
Journal: Blood
Blood (2024) 144 (Supplement 1): 772.
https://doi.org/10.1182/blood-2024-200336
Published: 2024
Journal Articles

Phase 3 Randomized Study of Daratumumab (DARA) + Bortezomib, Lenalidomide and Dexamethasone (VRd) Versus Alone in Patients with Transplant-Ineligible Newly Diagnosed Multiple Myeloma or for Whom Transplant Is Not Planned As Initial Therapy: Analysis of Minimal Residual Disease in the Cepheus Trial

Free
Sonja Zweegman, Thierry Facon, Vania Hungria, Nizar J. Bahlis, Christopher P. Venner, Marc Braunstein, Luděk Pour, Josep Marti Tutusaus, Supratik Basu, Yael C. Cohen, Morio Matsumoto, Kenshi Suzuki, Cyrille Hulin, Sebastian Grosicki, Wojciech Maciej Legiec, Meral Beksac, Angelo Maiolino, Hiroyuki Takamatsu, Aurore Perrot, Mehmet Turgut, Weiping Liu, Jianping Wang, Katherine Chastain, Jessica Vermeulen, Maria Krevvata, Lorena Lopez-Masi, Jodi Carey, Melissa Rowe, Robin Carson, Saad Z. Usmani
Journal: Blood
Blood (2024) 144 (Supplement 1): 362.
https://doi.org/10.1182/blood-2024-200871
Published: 2024
Journal Articles

Prognostic value of minimal residual disease negativity in myeloma: combined analysis of POLLUX, CASTOR, ALCYONE, and MAIA

Free
Clinical Trials & Observations
Michele Cavo, Jesus San-Miguel, Saad Z. Usmani, Katja Weisel, Meletios A. Dimopoulos, Hervé Avet-Loiseau, Bruno Paiva, Nizar J. Bahlis, Torben Plesner, Vania Hungria, Philippe Moreau, Maria-Victoria Mateos, Aurore Perrot, Shinsuke Iida, Thierry Facon, Shaji Kumar, Niels W. C. J. van de Donk, Pieter Sonneveld, Andrew Spencer, Maria Krevvata, Christoph Heuck, Jianping Wang, Jon Ukropec, Rachel Kobos, Steven Sun, Mia Qi, Nikhil Munshi
Journal: Blood
Blood (2022) 139 (6): 835–844.
https://doi.org/10.1182/blood.2021011101
Published: 2022
Includes: Supplemental data