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Stefanie Huhn
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Journal Articles

Feasibility and efficacy of daratumumab-vcd in transplant-ineligible elderly patients with newly diagnosed multiple myeloma: First results from the multicenter GMMG-dada study

Free
Christof Scheid, Christina Thielen, Sandra Willms, Axel Benner, Kaya Miah, Mathias Hänel, Peter Staib, Britta Besemer, Yon-Dschun Ko, Martin Schmidt-Hieber, Florian Kaiser, Timon Hansen, Maika Klaiber-Hakimi, Sebastian Theurich, Swen Wessendorf, Neise Michael, Christian Schmitt, Ullrich Graeven, Manfred Hensel, Cyrus Khandanpour, Joanna Millo, Stefanie Huhn, Michael Hundemer, Niels Weinhold, Marc Raab, Hartmut Goldschmidt, Tim Richardson
Journal: Blood
Blood (2025) 146 (Supplement 1): 4050.
https://doi.org/10.1182/blood-2025-4050
Published: 2025
Journal Articles

Peripheral residual disease activity assessment by MALDI-TOF mass spectrometry in patients with newly-diagnosed multiple myeloma in the GMMG-HD7 study

Free
Jia xiang Jin, Varun Ginde, Stefanie Huhn, Philipp Reichert, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Thorsten Peters-Regehr, Christof Scheid, Igor Wolfgang Blau, Carsten Mueller-Tidow, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Müller, Evgenii Shumilov, Wolfgang Knauf, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Niels Weinhold, Martin Hoffmann, Axel Benner, Peter Findeisen, Katja Weisel, Hans Salwender, Elias K. Mai, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 920.
https://doi.org/10.1182/blood-2025-920
Published: 2025
Journal Articles

Phylogenetic reconstruction reveals early divergence and late expansion of focal lesions in multiple myeloma

Free
Alexandra Poos, Lukas John, Kylee Maclachlan, Marc-Andrea Baertsch, Nina Prokoph, Juan-Jose Garces, Nina Hildenbrand, Christoph Rehnitz, Jan Frenking, Elias K. Mai, Philipp Reichert, Stefanie Huhn, Alexander Brobeil, Carsten Mueller-Tidow, Hartmut Goldschmidt, Saad Usmani, Sandra Sauer, Leo Rasche, Marc Raab, Francesco Maura, Niels Weinhold
Journal: Blood
Blood (2025) 146 (Supplement 1): 685.
https://doi.org/10.1182/blood-2025-685
Published: 2025
Journal Articles

Reprogrammed regulatory T cells as cytotoxic effectors drive anti-tumor immunity under bispecific T cell engager therapy

Free
Julius Michel, Jan Frenking, Anna Metzler, Erin Meermeier, Antonia Schach, Vera Thiel, Tim Wagner, Niklas Kehl, Stefanie Huhn, Alexander Brobeil, Carsten Müller-Tidow, P. Leif Bergsagel, Hartmut Goldschmidt, Hermann Einsele, Leo Rasche, Marta Chesi, Marc Raab, Niels Weinhold, Mirco Friedrich
Journal: Blood
Blood (2025) 146 (Supplement 1): 3951.
https://doi.org/10.1182/blood-2025-3951
Published: 2025
Journal Articles

Health-related quality of life (HRQoL) in patients with newly diagnosed multiple myeloma (NDMM) eligible for transplantation and treated with isatuximab, lenalidomide, bortezomib, and dexamethasone (Isa-RVd) versus rvd alone: Results from part 1 of the GMMG-HD7 study

Free
Elias K. Mai, Uta Bertsch, Roland Fenk, Britta Besemer, Amelie Boquoi, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Christian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc Raab, Martin Hoffmann, Erin Comerford, Maeva Kyheng, Feng Lin, Stephanie Rhoten, Tatiana Lavrova, Hans Salwender, Katja Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2025) 146 (Supplement 1): 2263.
https://doi.org/10.1182/blood-2025-2263
Published: 2025
Journal Articles

Phase 2 Study of Teclistamab-Based Induction Regimens in Patients with Transplant-Eligible (TE) Newly Diagnosed Multiple Myeloma (NDMM): Results from the GMMG-HD10/DSMM-XX (MajesTEC-5) Trial

Free
Marc S. Raab, Niels Weinhold, K. Martin Kortüm, Jan Krönke, Lilli Podola, Uta Bertsch, Jan H. Frenking, Julia Mersi, Stefanie Huhn, Michael Hundemer, Gunhild Mechtersheimer, Roland Fenk, Katja C. Weisel, Natalie Schub, Florian Bassermann, Monika Engelhardt, Raphael Teipel, Mathias Hänel, Hans Salwender, Bas D Koster, Elena Ershova, Caline Sakabedoyan, Isobel Barrott, Agnes Balogh, Sanjay Vara, Tobias Kampfenkel, Hartmut Goldschmidt, Hermann Einsele, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 493.
https://doi.org/10.1182/blood-2024-206003
Published: 2024
Journal Articles

Impact of Clonal Heterogeneity in Newly Diagnosed, Transplant-Eligible Multiple Myeloma - Subgroup Analysis of the GMMG HD6 Phase III Trial

Free
Maximilian Merz, Ema Pozek, Kaya Miah, Uta Bertsch, Britta Besemer, Mathias Hänel, Julia Krzykalla, Roland Fenk, Jana Schlenzka, Markus Munder, Christine Hanoun, Christoph Mann, Niels Weinhold, Christof Scheid, Roland Schroers, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Manfred Hensel, Axel Benner, Andrea Seidel-Glätzer, Katja C. Weisel, Marc S. Raab, Hans Salwender, Hartmut Goldschmidt, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 84.
https://doi.org/10.1182/blood-2024-201972
Published: 2024
Journal Articles

Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy for Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Final Progression-Free Survival Analysis of Part 1 of an Open-Label, Multicenter, Randomized, Phase 3 Trial (GMMG-HD7)

Free
Hartmut Goldschmidt, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Michael Hundemer, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc-Steffen Raab, Martin Hoffmann, Katja C. Weisel, Hans Salwender, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 769.
https://doi.org/10.1182/blood-2024-193308
Published: 2024
Journal Articles

Impact of Minimal Residual Disease on Progression-Free Survival in Patients with Newly Diagnosed Multiple Myeloma Treated with Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy in the Phase 3 GMMG-HD7 Trial

Free
Elias K. Mai, Hans Salwender, Michael Hundemer, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Niels Weinhold, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc S. Raab, Martin Hoffmann, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 364.
https://doi.org/10.1182/blood-2024-194768
Published: 2024
Journal Articles

The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma

Free
Anthony M. Cirrincione, Alexandra M. Poos, Bachisio Ziccheddu, Marcella Kaddoura, Marc-Andrea Bärtsch, Kylee Maclachlan, Monika Chojnacka, Benjamin Diamond, Lukas John, Philipp Reichert, Stefanie Huhn, Patrick Blaney, Dylan Gagler, Karsten Rippe, Yanming Zhang, Ahmet Dogan, Alexander M. Lesokhin, Faith Davies, Hartmut Goldschmidt, Roland Fenk, Katja C. Weisel, Elias K. Mai, Neha Korde, Gareth J. Morgan, Saad Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (7): 771–783.
https://doi.org/10.1182/blood.2024024299
Published: 2024
Includes: Supplemental data
Journal Articles

Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis

Free
Alexandra M. Poos, Nina Prokoph, Moritz J. Przybilla, Jan-Philipp Mallm, Simon Steiger, Isabelle Seufert, Lukas John, Stephan M. Tirier, Katharina Bauer, Anja Baumann, Jennifer Rohleder, Umair Munawar, Leo Rasche, K. Martin Kortüm, Nicola Giesen, Philipp Reichert, Stefanie Huhn, Carsten Müller-Tidow, Hartmut Goldschmidt, Oliver Stegle, Marc S. Raab, Karsten Rippe, Niels Weinhold
Journal: Blood
Blood (2023) 142 (19): 1633–1646.
https://doi.org/10.1182/blood.2023019758
Published: 2023
Includes: Supplemental data
Journal Articles

Immunological Subgroups Predicting Efficacy of Elotuzumab in Multiple Myeloma Patients: Insights from the GMMG-HD6 Clinical Trial

Free
Gigi Nu Hoang Quy Ton, Katharina Kriegsmann, Mohamed H.S. Awwad, Axel Benner, Uta Bertsch, Britta Besemer, Mathias Hänel, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Andreas Neubauer, Niels Weinhold, Christof Scheid, Roland Schroers, Ivana von Metzler, Aneta Schieferdecker, Jörg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glätzer, Katja Weisel, Hans Salwender, Carsten Müller-Tidow, Marc S. Raab, Hartmut Goldschmidt, Elias K. Mai, Michael Hundemer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1991.
https://doi.org/10.1182/blood-2023-189169
Published: 2023
Journal Articles

Bone Marrow Immune Signatures in Multiple Myeloma Are Linked to Tumor Heterogeneity and Treatment Outcome

Free
Simon Steiger, Raphael Lutz, Nina Prokoph, Subarna Palit, Stephan M Tirier, Philipp Reichert, Anja Baumann, Nadine Hefner, Sabrina Schumacher, Dominik Vonficht, Florian Grünschläger, Alexandra M Poos, Lukas John, Laleh Haghverdi, Jan-Philipp Mallm, Elias K Mai, Mirco Friedrich, Katharina Kriegsmann, Mohamed H.S. Awwad, Anna Jauch, Uta Bertsch, Diana Tichy, Carsten Müller-Tidow, Roland Schroers, Hans Salwender, Britta Besemer, Roland Fenk, Katja Weisel, Hartmut Goldschmidt, Stefanie Huhn, Michael Hundemer, Karsten Rippe, Simon Haas, Niels Weinhold, Marc S Raab
Journal: Blood
Blood (2022) 140 (Supplement 1): 2083–2085.
https://doi.org/10.1182/blood-2022-168685
Published: 2022
Journal Articles

Single-Cell Multi-Omics Reveal Longitudinal Dynamics of Clonal Architecture and Microenvironment Interactions in Relapsed-Refractory Myeloma

Free
Alexandra M. Poos, Nina Prokoph, Moritz J. Przybilla, Jan-Philipp Mallm, Simon Steiger, Isabelle Lander, Lukas John, Stephan M Tirier, Katharina Bauer, Anja Baumann, Umair Munawar, Leo Rasche, Martin Kortuem, Nicola Giesen, Stefanie Huhn, Carsten Mueller-Tidow, Hartmut Goldschmidt, Oliver Stegle, Marc S Raab, Karsten Rippe, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 9987–9988.
https://doi.org/10.1182/blood-2022-166105
Published: 2022
Journal Articles

The Landscape of Small Nucleolar RNA Expression in Multiple Myeloma

Free
Duoduo Zhao, Christian Rohde, Fengbiao Zhou, Anna Luise Grab, Alexandra M Poos, Lukas John, Stefanie Huhn, Marc S Raab, Carsten Mueller-Tidow, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 10013–10014.
https://doi.org/10.1182/blood-2022-166268
Published: 2022
Journal Articles

Implications and Prognostic Impact of Mass Spectrometry in Patients with Newly-Diagnosed Multiple Myeloma

Free
Elias K Mai, Stefanie Huhn, Kaya Miah, Alexandra M Poos, Christof Scheid, Katja Weisel, Uta Bertsch, Markus Munder, Oscar Berlanga, Dirk Hose, Anja Seckinger, Anna Jauch, Igor Wolfgang Blau, Mathias Haenel, Hans Salwender, Axel Benner, Marc S Raab, Hartmut Goldschmidt, Niels Weinhold
Journal: Blood
Blood (2022) 140 (Supplement 1): 2341–2343.
https://doi.org/10.1182/blood-2022-156169
Published: 2022
Journal Articles

Elotuzumab in Combination with Lenalidomide, Bortezomib, Dexamethasone and Autologous Transplantation for Newly-Diagnosed Multiple Myeloma: Results from the Randomized Phase III GMMG-HD6 Trial

Free
Hartmut Goldschmidt, Elias K Mai, Uta Bertsch, Britta Besemer, Mathias Haenel, Kaya Miah, Roland Fenk, Jana Schlenzka, Markus Munder, Jan Dürig, Igor Wolfgang Blau, Stefanie Huhn, Dirk Hose, Anna Jauch, Christina Kunz, Andreas Neubauer, Christof Scheid, Roland Schroers, Ivana v. Metzler, Aneta Schieferdecker, Joerg Thomalla, Peter Reimer, Rolf Mahlberg, Ullrich Graeven, Stephan Kremers, Uwe M. Martens, Christian Kunz, Manfred Hensel, Andrea Seidel-Glaetzer, Katja Weisel, Marc-Steffen Raab, Hans Salwender
Journal: Blood
Blood (2021) 138 (Supplement 1): 486.
https://doi.org/10.1182/blood-2021-147323
Published: 2021
Journal Articles

Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients: The Phase III GMMG-HD7 Trial

Free
Hartmut Goldschmidt, Elias K Mai, Eva Nievergall, Roland Fenk, Uta Bertsch, Diana Tichy, Britta Besemer, Jan Dürig, Roland Schroers, Ivana v. Metzler, Mathias Haenel, Christoph Mann, Anne-Marie Asemissen, Bernhard Heilmeier, Stefanie Huhn, Katharina Kriegsmann, Niels Weinhold, Steffen P. Luntz, Tobias A. W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Cyrus Khandanpour, Wolfgang Knauf, Markus Munder, Thomas Geer, Hendrik Riesenberg, Joerg Thomalla, Martin Hoffmann, Marc-Steffen Raab, Hans Salwender, Katja Weisel
Journal: Blood
Blood (2021) 138 (Supplement 1): 463.
https://doi.org/10.1182/blood-2021-145097
Published: 2021
Journal Articles

The Spatial Heterogeneity in Newly Diagnosed Multiple Myeloma Patients - from Sub-Clonal Architecture to the Immune Microenvironment

Free
Lukas John, Alexandra Poos, Stephan M Tirier, Jan-Philipp Mallm, Nina Prokoph, Alexander Brobeil, Raphael Lutz, Sabrina Schumacher, Simon Steiger, Katharina Bauer, Anja Baumann, Christoph Rehnitz, Carsten Müller-Tidow, Hartmut Goldschmidt, Stefanie Huhn, Karsten Rippe, Marc-Steffen Raab, Sandra Sauer, Niels Weinhold
Journal: Blood
Blood (2021) 138 (Supplement 1): 729.
https://doi.org/10.1182/blood-2021-150937
Published: 2021
Journal Articles

Comprehensive Comparison of Early Relapse and End-Stage Relapsed Refractory Multiple Myeloma

Free
Alexandra M Poos, PhD, Nicola Giesen, MD, Calogerina Catalano, PhD, Nagarajan Paramasivam, PhD, Daniel Huebschmann, MDPhD, Lukas John, Anja Baumann, Jason Hochhaus, Carsten Mueller-Tidow, MD, Sandra Sauer, MD, Stefanie Huhn, PhD, Matthias Schlesner, PhD, Benedikt Brors, PhD, Hartmut Goldschmidt, MD, Marc S. Raab, MD, Niels Weinhold, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
https://doi.org/10.1182/blood-2020-141611
Published: 2020