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Deniz Gezer
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Journal Articles

Impact of Minimal Residual Disease on Progression-Free Survival in Patients with Newly Diagnosed Multiple Myeloma Treated with Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy in the Phase 3 GMMG-HD7 Trial

Elias K. Mai, Hans Salwender, Michael Hundemer, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Niels Weinhold, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc S. Raab, Martin Hoffmann, Katja C. Weisel, Hartmut Goldschmidt
Journal: Blood
Blood (2024) 144 (Supplement 1): 364.
https://doi.org/10.1182/blood-2024-194768
Published: 2024
Journal Articles

Isatuximab, Lenalidomide, Bortezomib and Dexamethasone Induction Therapy for Transplant-Eligible Patients with Newly Diagnosed Multiple Myeloma: Final Progression-Free Survival Analysis of Part 1 of an Open-Label, Multicenter, Randomized, Phase 3 Trial (GMMG-HD7)

Hartmut Goldschmidt, Uta Bertsch, Ema Pozek, Axel Benner, Roland Fenk, Britta Besemer, Christine Hanoun, Roland Schroers, Ivana von Metzler, Mathias Hänel, Christoph Mann, Lisa Leypoldt, Bernhard Heilmeier, Stefanie Huhn, Sabine Vogel, Michael Hundemer, Christof Scheid, Igor Wolfgang Blau, Steffen Luntz, Tobias A.W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Evgenii Shumilov, Wolfgang Knauf, Christian Sebastian Michel, Thomas Geer, Hendrik Riesenberg, Christoph Lutz, Marc-Steffen Raab, Martin Hoffmann, Katja C. Weisel, Hans Salwender, Elias K. Mai
Journal: Blood
Blood (2024) 144 (Supplement 1): 769.
https://doi.org/10.1182/blood-2024-193308
Published: 2024
Journal Articles

Real-World Analysis of Teclistamab in 115 RRMM Patients from Germany

Christine Riedhammer, Florian Bassermann, Britta Besemer, Moritz Bewarder, Franziska Brunner, Alexander Carpinteiro, Hermann Einsele, Josefine Faltin, Jan Frenking, Deniz Gezer, Sarah Goldman-Mazur, Mathias Hanel, Marion Hoegner, K. Martin Kortüm, Jan Krönke, Miriam Kull, Theo Leitner, Christoph Mann, Rabea Mecklenbrauck, Maximilian Merz, Anke Morgner, Axel Nogai, Marc S. Raab, Raphael Teipel, Ralph Wäsch, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 3329.
https://doi.org/10.1182/blood-2023-180032
Published: 2023
Journal Articles

Ruxolitinib Versus Best Available Therapy in Patients with Essential Thrombocythemia: Pre-Specified Interim Analysis of the Randomized Phase 2b Ruxobeat Clinical Trial of the German Study Group for Myeloproliferative Neoplasms (GSG-MPN)

Steffen Koschmieder, Susanne Isfort, Florian H. Heidel, Andreas Hochhaus, Heiko Becker, Philipp J. Jost, Philippe Schafhausen, Martin Griesshammer, Denise Wolleschak, Mathias Haenel, Joachim R Göthert, Lino L. Teichmann, Katja Sockel, Markus P. Radsak, Andreas Reiter, Konstanze Döhner, Sebastian Balleisen, Nadja Jaekel, Nikolas von Bubnoff, Frank Stegelmann, Deniz Gezer, Maike Kortmann, Julia Frank, Martin Hellmich, Tim H. Brümmendorf
Journal: Blood
Blood (2022) 140 (Supplement 1): 1790–1793.
https://doi.org/10.1182/blood-2022-157265
Published: 2022
Journal Articles

Addition of Isatuximab to Lenalidomide, Bortezomib and Dexamethasone As Induction Therapy for Newly-Diagnosed, Transplant-Eligible Multiple Myeloma Patients: The Phase III GMMG-HD7 Trial

Hartmut Goldschmidt, Elias K Mai, Eva Nievergall, Roland Fenk, Uta Bertsch, Diana Tichy, Britta Besemer, Jan Dürig, Roland Schroers, Ivana v. Metzler, Mathias Haenel, Christoph Mann, Anne-Marie Asemissen, Bernhard Heilmeier, Stefanie Huhn, Katharina Kriegsmann, Niels Weinhold, Steffen P. Luntz, Tobias A. W. Holderried, Karolin Trautmann-Grill, Deniz Gezer, Maika Klaiber-Hakimi, Martin Mueller, Cyrus Khandanpour, Wolfgang Knauf, Markus Munder, Thomas Geer, Hendrik Riesenberg, Joerg Thomalla, Martin Hoffmann, Marc-Steffen Raab, Hans Salwender, Katja Weisel
Journal: Blood
Blood (2021) 138 (Supplement 1): 463.
https://doi.org/10.1182/blood-2021-145097
Published: 2021
Journal Articles

JAK2 -mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms

Tata Nageswara Rao, Nils Hansen, Julian Hilfiker, Shivam Rai, Julia-Magdalena Majewska, Danijela Leković, Deniz Gezer, Nicola Andina, Serena Galli, Teresa Cassel, Florian Geier, Julien Delezie, Ronny Nienhold, Hui Hao-Shen, Christian Beisel, Serena Di Palma, Sarah Dimeloe, Jonel Trebicka, Dominik Wolf, Max Gassmann, Teresa W.-M. Fan, Andrew N. Lane, Christoph Handschin, Stefan Dirnhofer, Nicolaus Kröger, Christoph Hess, Thomas Radimerski, Steffen Koschmieder, Vladan P. Čokić, Radek C. Skoda
Journal: Blood
Blood (2019) 134 (21): 1832–1846.
https://doi.org/10.1182/blood.2019000162
Published: 2019
Includes: Supplemental data
Journal Articles

STAT1 Transcriptional Response Predicts Molecular Responses of PB-Derived Clonogenic Cells from MPN Patients to Interferon Alpha

Milena Kalmer, MSc, Kristina Feldberg, Deniz Gezer, Susanne Isfort, Tim H Brümmendorf, MD, Nicolas Chatain, Steffen Koschmieder
Journal: Blood
Blood (2019) 134 (Supplement_1): 1679.
https://doi.org/10.1182/blood-2019-122676
Published: 2019
Journal Articles

Ruxolitinib Shows Efficacy in Patients with Newly-Diagnosed Polycythemia Vera: Futility Analysis of the Randomized Ruxo-BEAT Clinical Trial of the German Study Group for Myeloproliferative Neoplasms

Steffen Koschmieder, Susanne Isfort, Dominik Wolf, Univ. Prof. Dr., Florian H. Heidel, Philippe Schafhausen, Martin Griesshammer, MD, Denise Wolleschak, Uwe Platzbecker, Konstanze Döhner, Philipp J. Jost, MD, Stefani B. Parmentier, Nikolas von Bubnoff, Frank Stegelmann, MD, Angela Maurer, Jeremy Franklin, Martina Crysandt, MD, Deniz Gezer, Martin Hellmich, Tim H Brümmendorf, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2944.
https://doi.org/10.1182/blood-2019-123985
Published: 2019
Journal Articles

Comorbidities Such As Thromboembolic Events Significantly Worsen Patient-Reported Quality of Life (QoL) and Symptoms in Myeloproliferative Neoplasms (MPN) - Data from the Bioregistry of the German Study Group for MPN (GSG-MPN)

Susanne Isfort, Frank Stegelmann, MD, Martine Klausmann, MD, Holger Schulz, Wiebke Hollburg, MD, Haifa Kathrin Al-Ali, Joachim R. Goethert, MD, Florian H. Heidel, MD, Christoph Maintz, MD, Mathias Haenel, MD, Uwe Platzbecker, Richard Hansen, MD, Andras Keszei, MD, Judith Gecht, Kim Kricheldorf, Andrea Kaifie, MD, Martina Crysandt, Deniz Gezer, MD, Martin Griesshammer, MD PhD, Tim H Brümmendorf, MD, Konstanze Döhner, MD, Steffen Koschmieder, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4292.
https://doi.org/10.1182/blood-2018-99-112377
Published: 2018
Journal Articles

Implication of Hypoxia-Inducible Factor-1 (HIF-1) As a New Therapeutic Target in JAK2 V617F Positive Myeloproliferative Neoplasms (MPN)

Julian Baumeister, MSc, Nicolas Chatain, PhD, Annika Hubrich, Caroline Küstermann, M.Sc., Stephanie Sontag, PhD, Kristin Seré, PhD, Martin Zenke, PhD, Tim H Brümmendorf, MD, Kamil Kranc, MD, Steffen Koschmieder, MD, Deniz Gezer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2018-99-113332
Published: 2018
Journal Articles

Eosinophil Differentiation and Viability in Hypereosinophilia Is Impaired By Genetic and Pharmacologic Targeting of LCP1 and PKC Beta

Guangxin Ma, Deniz Gezer, MD, Oliver Herrmann, Msc, Andreas Reiter, MD, Mohamad Jawhar, Mirle Schemionek, Tim H. Brümmendorf, MD, Steffen Koschmieder, MD, Nicolas Chatain, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4320.
https://doi.org/10.1182/blood-2018-99-114646
Published: 2018
Journal Articles

the IKZF1-IRF4 Axis Regulates Macrophage Polarization and Macrophage-Mediated Anti-Tumor Immunity

Heiko Bruns, PhD, Dimitrios Mougiakakos, Christian Bach, Martin Böttcher, Joerg Thomas Bittenbring, MD, Maike Büttner, Kolja Gelse, Michael Rehli, Julia Wimmer, Fabian Beier, MD, Deniz Gezer, Jan Krönke, MD, Heidi Balzer, Stephanie Moi, Bernd Spriewald, MD, Andreas Mackensen, MD, Leonhard Busch
Journal: Blood
Blood (2016) 128 (22): 2514.
https://doi.org/10.1182/blood.V128.22.2514.2514
Published: 2016
Journal Articles

Adult hematopoietic stem cells lacking Hif-1α self-renew normally

Brief Report
Milica Vukovic, Catarina Sepulveda, Chithra Subramani, Amélie V. Guitart, Jasmine Mohr, Lewis Allen, Theano I. Panagopoulou, Jasmin Paris, Hannah Lawson, Arnaud Villacreces, Alejandro Armesilla-Diaz, Deniz Gezer, Tessa L. Holyoake, Peter J. Ratcliffe, Kamil R. Kranc
Journal: Blood
Blood (2016) 127 (23): 2841–2846.
https://doi.org/10.1182/blood-2015-10-677138
Published: 2016
Includes: Supplemental data
Journal Articles

HIF-1α Is Not Essential For The Establishment Of MLL-Leukaemic Stem Cells

Deniz Gezer, Amelie V Guitart, Milica Vukovic, Chithra Subramani, Karen Dunn, Patrick Pollard, Peter J Ratcliffe, Tessa L. Holyoake, PhD, Kamil Kranc
Journal: Blood
Blood (2013) 122 (21): 3767.
https://doi.org/10.1182/blood.V122.21.3767.3767
Published: 2013
Journal Articles

Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance

Brief Report
Amelie V. Guitart, Chithra Subramani, Alejandro Armesilla-Diaz, Gillian Smith, Catarina Sepulveda, Deniz Gezer, Milica Vukovic, Karen Dunn, Patrick Pollard, Tessa L. Holyoake, Tariq Enver, Peter J. Ratcliffe, Kamil R. Kranc
Journal: Blood
Blood (2013) 122 (10): 1741–1745.
https://doi.org/10.1182/blood-2013-02-484923
Published: 2013
Includes: Supplemental data
Journal Articles

Epigenetic Inactivation of the Secreted Frizzled-Related Protein Gene Family in Multiple Myeloma.

Edgar Jost, MD, Deniz Gezer, Stefan Wilop, MD, James G. Herman, MD, Rainhardt Osieka, MD, Oliver Galm, MD
Journal: Blood
Blood (2007) 110 (11): 2131.
https://doi.org/10.1182/blood.V110.11.2131.2131
Published: 2007