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Kamil Kranc
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Journal Articles

Targeting HIF-Hydroxylases Compromises Disease Initiation and Propagation, and Synergises with Current Therapies to Eliminate Cancer Stem Cells in AML

Hannah Lawson, James Holt-Martyn, Vilma Dembitz, Jozef Durko, Yuka Kabayama, Lydia Wang, Louie Van De Lagemaat, Louis Dubusse, Laura Alunno, Amelie Guitart, Jürg Schwaller, Paolo Gallipoli, Dónal O'Carroll, Christopher Schofield, Kamil Kranc
Journal: Blood
Blood (2022) 140 (Supplement 1): 8731–8732.
https://doi.org/10.1182/blood-2022-165192
Published: 2022
Journal Articles

Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia

Vilma Dembitz, Hannah Lawson, Celine Philippe, Richard J. Burt, Sophie James, Aoife S.M. Magee, Keith Woodley, Jozef Durko, Joana Campos, Michael James Austin, Ana Rio-Machin, Pedro Casado Izquierdo, Findlay Bewicke-Copley, Giovanny Rodriguez Blanco, Bela Patel, Lori Hazlehurst, Barrie Peck, Andrew Finch, Pedro Cutillas, Jude Fitzgibbon, Mariia Yuneva, Kevin Rouault-Pierre, John Copland, III, Kamil Kranc, Paolo Gallipoli
Journal: Blood
Blood (2022) 140 (Supplement 1): 3058–3060.
https://doi.org/10.1182/blood-2022-166811
Published: 2022
Journal Articles

Genetic and Pharmacological Inhibition of TUT4/TUT7 Sensitizes AML Cells to BCL-2 Inhibition

Corey Fyfe, Gabriella Fiorentino, Michael Steinbaugh, Joana Campos, Hannah Lawson, Jozef Durko, Dónal O'Carroll, Kamil Kranc, Darren Harvey, Shomir Ghosh, Robert M Campbell
Journal: Blood
Blood (2022) 140 (Supplement 1): 12994.
https://doi.org/10.1182/blood-2022-169052
Published: 2022
Journal Articles

Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia

Denise Ragusa, Chun-Wai Suen, Gabriel Torregrosa, Liza Dijkhuis, Connor Byrne, Tina Balayo, Andrea Tavosanis, Jozef Durko, Kristen Place, Ana Filipa Domingues, Kamil Kranc, Jordi Garcia-Ojalvo, Alfonso Martinez Arias, Cristina Pina
Journal: Blood
Blood (2022) 140 (Supplement 1): 1684–1685.
https://doi.org/10.1182/blood-2022-169733
Published: 2022
Journal Articles

Implication of Hypoxia-Inducible Factor-1 (HIF-1) As a New Therapeutic Target in JAK2 V617F Positive Myeloproliferative Neoplasms (MPN)

Julian Baumeister, MSc, Nicolas Chatain, PhD, Annika Hubrich, Caroline Küstermann, M.Sc., Stephanie Sontag, PhD, Kristin Seré, PhD, Martin Zenke, PhD, Tim H Brümmendorf, MD, Kamil Kranc, MD, Steffen Koschmieder, MD, Deniz Gezer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2018-99-113332
Published: 2018
Journal Articles

HIF-1α Is Not Essential For The Establishment Of MLL-Leukaemic Stem Cells

Deniz Gezer, Amelie V Guitart, Milica Vukovic, Chithra Subramani, Karen Dunn, Patrick Pollard, Peter J Ratcliffe, Tessa L. Holyoake, PhD, Kamil Kranc
Journal: Blood
Blood (2013) 122 (21): 3767.
https://doi.org/10.1182/blood.V122.21.3767.3767
Published: 2013