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Alexandra Schurer
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Journal Articles

Efficacy of a Novel BCL-XL Degrader, DT2216, in Preclinical Models of Post-Myeloproliferative Neoplasm Secondary AML

Zhe Wang, Anna Skwarska, Gowri Poigailwar, Sovira Chaudhry, Alba Rodriguez-Meira, Pinpin Sui, Emmanuel Olivier, Yannan Jia, Cassandra L. Ramage, Guangrong Zheng, Alexandra Schurer, Kira Gritsman, Eirini Papapetrou, Kapil N. Bhalla, Daohong Zhou, Adam J Mead, Raajit Rampal, Jeffrey W Tyner, Hussein A. Abbas, Naveen Pemmaraju, Qi Zhang Tatarata, Marina Konopleva
Journal: Blood
Blood (2024) 144 (Supplement 1): 2749.
https://doi.org/10.1182/blood-2024-194031
Published: 2024
Journal Articles

Differential Requirements for the RON Ligand Binding and Kinase Domains in Myeloproliferative Neoplasms

Alexandra Schurer, Lindsay Gurska, Yuxuan Wang, Allison Montoya, Swati Goel, Kira Gritsman
Journal: Blood
Blood (2024) 144 (Supplement 1): 1751.
https://doi.org/10.1182/blood-2024-210545
Published: 2024
Journal Articles

Dual IKZF2 and CK1α Degrader Targets Acute Myeloid Leukemia Cells

Sun Mi Park, David Miyamoto, Grace Han, Mandy Chan, Nicole Curnutt, Nathan Tran, Anthony Velleca, Jun Hyun Kim, Alexandra Schurer, Kathryn Chang, Christina M Woo, Michael G Kharas
Journal: Blood
Blood (2022) 140 (Supplement 1): 675–676.
https://doi.org/10.1182/blood-2022-167678
Published: 2022
Journal Articles

RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality

Florisela Herrejon Chavez, Paolo Cifani, Alli Pine, Karen L Chu, Ersilia Barin, Alexandra Schurer, Hanzhi Luo, Diu T.T. Nguyen, Alex Kentsis, Christina Leslie, Michael G Kharas, Ly P Vu
Journal: Blood
Blood (2021) 138 (Supplement 1): 296.
https://doi.org/10.1182/blood-2021-147575
Published: 2021
Journal Articles

Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia

Diu T.T. Nguyen, DPhil, Camila Prieto, PhD, Zhaoqi Liu, PhD, Justin Wheat, Alexendar Perez, Saroj Gourkanti, BA, Timothy Chou, BS, Ersilia Barin, Arthur Chow, BS, James Taggart, BA, Katerina Hoskova, Meera Dhodapkar, Alexandra Schurer, BS, Trevor Stephen Barlowe, BA, Ly Vu, PhD, Christina Leslie, PhD, Ulrich G. Steidl, MDPhD, Raul Rabadan, PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15.
https://doi.org/10.1182/blood-2020-142229
Published: 2020
Journal Articles

m 6 A Maintains Hematopoietic Stem and Progenitor Cell Identity

Yuanming Cheng, PhD, Hanzhi Luo, PhD, Franco Izzo, PhD, Brian F Pickering, PhD, Ly P Vu, PhD, Alexandra Schurer, BS, Saroj Gourkanti, BA, Samie R. Jaffrey, MD PhD, Dan A. Landau, MD PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 327.
https://doi.org/10.1182/blood-2018-99-117191
Published: 2018
Journal Articles

RNA Binding Protein Rbmx Is Required in Acute Myeloid Leukemia By Regulating the Transcriptional Activity of the Heterochromatin Protein HP1α

Camila Prieto, BA, Diu Nguyen, PhD, Ly P Vu, PhD, Alexendar Perez, PhD, Saroj Gourkanti, BA, Alexandra Schurer, BS, Timothy Chou, BS, Arthur Chow, BA, James Taggart, BA, Trevor Stephen Barlowe, BA, Christina Leslie, PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 883.
https://doi.org/10.1182/blood-2018-99-112543
Published: 2018
Journal Articles

Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia

Gerard Minuesa Dinares, PhD, Steven K. Albanese, BS, Arthur Chow, BA, Alexandra Schurer, BS, Sun Mi Park, PhD, Christina Z. Rotsides, PhD, James Taggart, BS, Andrea Rizzi, BS, Levi N. Naden, PhD, Timothy Chou, BS, Saroj Gourkanti, BA, Daniel Cappel, PhD, Maria C. Passarelli, BS, Lauren Fairchild, PhD, Carolina Adura, PhD, Joseph Fraser Glickman, MSPH, PhD, Jessica Schulman, Christopher Famulare, MS, Minal Patel, BA, Joseph K. Eibl, PhD, Gregory M. Ross, PhD, Derek Tan, PhD, Christina Leslie, PhD, Thijs Beuming, PhD, Yehuda Goldgur, PhD, John D. Chodera, PhD, Michael G. Kharas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 428.
https://doi.org/10.1182/blood-2018-99-118745
Published: 2018